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Search results 1 to 98 out of 98 for Ethe1

0.188s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
23474 | ETHE1
Type: gene
Organism: human
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Gene
612416 | ETHE1
Type: gene
Organism: dog, domestic
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Gene
456093 | ETHE1
Type: gene
Organism: chimpanzee
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Gene
509150 | ETHE1
Type: gene
Organism: cattle
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Gene
405865 | ethe1
Type: gene
Organism: zebrafish
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Gene
718089 | ETHE1
Type: gene
Organism: macaque, rhesus
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Gene
448221 | ethe1
Type: gene
Organism: frog, western clawed
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Gene
292710 | Ethe1
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1913321 | Ethe1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
19136963 | J:146537
First Author: Tiranti V
Year: 2009
Journal: Nat Med
Title: Loss of ETHE1, a mitochondrial dioxygenase, causes fatal sulfide toxicity in ethylmalonic encephalopathy.
Volume: 15
Issue: 2
Pages: 200-5
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Protein Coding Gene
MGP_CAROLIEiJ_G0029342 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031836 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031815 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031744 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031821 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031541 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1913321 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032284 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030882 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031506 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031660 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031613 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031739 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031650 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032316 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030606 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030985 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021193 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030436 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304872
Note: kidney
Specimen Label: MRC Harwell_1304872
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1666528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304866
Specimen Label: MRC Harwell_1304866
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:1706828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304868
Specimen Label: MRC Harwell_1304868
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1006477
Assay Type: RNA in situ
Annotation Date: 2023-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7525209
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1925228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304869
Specimen Label: MRC Harwell_1304869
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1898428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304873
Specimen Label: MRC Harwell_1304873
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3667028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304863
Specimen Label: MRC Harwell_1304863
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1720228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304865
Specimen Label: MRC Harwell_1304865
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1860128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304870
Specimen Label: MRC Harwell_1304870
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304867
Specimen Label: MRC Harwell_1304867
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304871
Specimen Label: MRC Harwell_1304871
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:1006477
Assay Type: RNA in situ
Annotation Date: 2023-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7525209
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3590528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304872
Specimen Label: MRC Harwell_1304872
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3590528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304874
Specimen Label: MRC Harwell_1304874
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304871
Specimen Label: MRC Harwell_1304871
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304875
Specimen Label: MRC Harwell_1304875
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304868
Specimen Label: MRC Harwell_1304868
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304873
Specimen Label: MRC Harwell_1304873
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304861
Specimen Label: MRC Harwell_1304861
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304862
Specimen Label: MRC Harwell_1304862
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691646
Age: postnatal adult
Image: MRC Harwell_1304864
Specimen Label: MRC Harwell_1304864
Detected: true
Specimen Num: 12
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Publication
14651853 | J:86816
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
30391543 | J:270374
First Author: Sahebekhtiari N
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Deficiency of the mitochondrial sulfide regulator ETHE1 disturbs cell growth, glutathione level and causes proteome alterations outside mitochondria.
Volume: 1865
Issue: 1
Pages: 126-135
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Publication
22786886 | -
First Author: Holdorf MM
Year: 2012
Journal: Plant Physiol
Title: Arabidopsis ETHE1 encodes a sulfur dioxygenase that is essential for embryo and endosperm development.
Volume: 160
Issue: 1
Pages: 226-36
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Protein
Q9DCM0
Organism: Mus musculus/domesticus
Length: 254  
Fragment?: false
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Allele
Ethe1<tm1.1Zev> | MGI:3838184
Name: ethylmalonic encephalopathy 1; targeted mutation 1.1, Massimo Zeviani
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Ethe1/Ethe1
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0060640 | ethylmalonic encephalopathy
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Publication
26082492 | -
First Author: Sattler SA
Year: 2015
Journal: J Biol Chem
Title: Characterizations of Two Bacterial Persulfide Dioxygenases of the Metallo-β-lactamase Superfamily.
Volume: 290
Issue: 31
Pages: 18914-23
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Publication
25596185 | -
First Author: Pettinati I
Year: 2015
Journal: Hum Mol Genet
Title: Crystal structure of human persulfide dioxygenase: structural basis of ethylmalonic encephalopathy.
Volume: 24
Issue: 9
Pages: 2458-69
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Protein Domain
IPR044528 | POD-like_MBL-fold
Type: Domain
Description: Persulfide dioxygenase (PDO, also known as sulfur dioxygenase, SDO, ) is a non-heme iron-dependent oxygenase that catalyses the oxidation of glutathione persulfide (GSSH) to glutathione (GSH) and persulfite and play important and varied roles in all kingdoms, including sulfide detoxification []. These enzymes belong to the metallo-beta-lactamase (MBL) superfamily as they consist of the same structural fold of two β-sheets surrounded by α-helices, which supports the metal-binding feature. The PDOs share high sequence and structural similarity with glyoxalases II (classical di-zinc MBL hydrolase), specially at the metal-binding centre. PDOs have a Fe2 binding site and a secondary coordination sphere-based hydrogen bond network that is absent in glyoxalases II, in which the corresponding residues are involved in coordinating a second metal ion. This suggests that PDOs may evolve from a hydrolytic enzyme with two coordinated ions []. Based on sequence analysis, three subclasses of PDO were described: ETHE1, which is present in animals, plants, and bacteria (in the latter they are also called type 1 PDOs), persulfide dioxygenase A (PDOA, or type 2 PDOs), also known as sulfur dioxygenase A (SdoA), which is common in Proteobacteria, and Blh, which is an acronym for beta-lactamase-like hydrolase []. In humans, mutations in PDO ETHE1 cause a rare autosomal recessive metabolic disorder called ethylmalonic encephalopathy []. In Arabidopsis thaliana, ETHE1 is essential for embryo and endosperm development [].This entry represents the MBL-fold metallo-hydrolase domain.
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