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Search results 1 to 100 out of 313 for Ewsr1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Domain
Type: Family
Description: RNA-binding protein EWS (also known as EWSR1) participates in transcriptional regulation and RNA processing. It is structurally and functionally related to FUS (TLS) protein []. EWSR1 gene rearrangements are often observed in myoepithelial tumours [, ].TAF15/EWS/TLS family members include human FUS (Fused in liposarcoma), EWS (Ewing Sarcoma) and TAF15 (TATA binding associated factor 15), and the Drosophila orthologue Cabeza. They are RNA binding proteins that contain a transcriptional-activation domain (EAD), 3 glycine-arginine (RGG) rich regions, an RNA-binding domain (RBD), and a zinc finger domain [, ]. They are involved in transcription and alternative splicing. They are subjected to different environmental signals that induce post-translational modifications in their RBD and in the RGG domains, thus modulating their activity []. TAF15/EWS/TLS play important roles in oncogenesis and neuronal disease [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication  
First Author: Tian H
Year: 2021
Journal: Development
Title: Mouse EWSR1 is crucial for spermatid post-meiotic transcription and spermiogenesis.
Volume: 148
Issue: 11
Publication
First Author: Kim Y
Year: 2015
Journal: Autophagy
Title: Uvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiency.
Volume: 11
Issue: 5
Pages: 796-811
Publication
First Author: Wang Y
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Gammaherpesvirus-mediated repression reveals EWSR1 to be a negative regulator of B cell responses.
Volume: 119
Issue: 32
Pages: e2123362119
Publication  
First Author: Tanaka M
Year: 2015
Journal: Sci Rep
Title: Somatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model.
Volume: 5
Pages: 7826
Publication
First Author: Jung JW
Year: 2023
Journal: Sci Rep
Title: In-depth proteome analysis of brain tissue from Ewsr1 knockout mouse by multiplexed isobaric tandem mass tag labeling.
Volume: 13
Issue: 1
Pages: 15261
Publication
First Author: Tian H
Year: 2021
Journal: Mol Biol Cell
Title: EWSR1 affects PRDM9-dependent histone 3 methylation and provides a link between recombination hotspots and the chromosome axis protein REC8.
Volume: 32
Issue: 1
Pages: 1-14
Publication
First Author: Yamamoto-Shiraishi Y
Year: 2014
Journal: Dev Biol
Title: Etv1 and Ewsr1 cooperatively regulate limb mesenchymal Fgf10 expression in response to apical ectodermal ridge-derived fibroblast growth factor signal.
Volume: 394
Issue: 1
Pages: 181-90
Publication  
First Author: Luo Y
Year: 2015
Journal: BMC Genomics
Title: EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions.
Volume: 16
Pages: 929
Publication
First Author: Huang SC
Year: 2015
Journal: Genes Chromosomes Cancer
Title: Novel FUS-KLF17 and EWSR1-KLF17 fusions in myoepithelial tumors.
Volume: 54
Issue: 5
Pages: 267-75
Publication
First Author: Agaram NP
Year: 2015
Journal: Genes Chromosomes Cancer
Title: EWSR1-PBX3: a novel gene fusion in myoepithelial tumors.
Volume: 54
Issue: 2
Pages: 63-71
Protein
Organism: Mus musculus/domesticus
Length: 325  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 354  
Fragment?: false
Publication
First Author: Chau BL
Year: 2016
Journal: Transcription
Title: RGG boxes within the TET/FET family of RNA-binding proteins are functionally distinct.
Volume: 7
Issue: 4
Pages: 141-51
Publication
First Author: Svetoni F
Year: 2016
Journal: RNA Biol
Title: Role of FET proteins in neurodegenerative disorders.
Volume: 13
Issue: 11
Pages: 1089-1102
Publication
First Author: Hoell JI
Year: 2011
Journal: Nat Struct Mol Biol
Title: RNA targets of wild-type and mutant FET family proteins.
Volume: 18
Issue: 12
Pages: 1428-31
Protein
Organism: Mus musculus/domesticus
Length: 655  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 333  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 655  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 618  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 661  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 656  
Fragment?: false
Publication
First Author: Yoon Y
Year: 2018
Journal: Exp Neurobiol
Title: Genetic Ablation of EWS RNA Binding Protein 1 (EWSR1) Leads to Neuroanatomical Changes and Motor Dysfunction in Mice.
Volume: 27
Issue: 2
Pages: 103-111
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Plougastel B
Year: 1994
Journal: Genomics
Title: Cloning and chromosome localization of the mouse Ews gene.
Volume: 23
Issue: 1
Pages: 278-81
Publication
First Author: Kang HJ
Year: 2014
Journal: Cancer Res
Title: EWS-WT1 oncoprotein activates neuronal reprogramming factor ASCL1 and promotes neural differentiation.
Volume: 74
Issue: 16
Pages: 4526-35
Publication
First Author: Codrington R
Year: 2005
Journal: PLoS Biol
Title: The Ews-ERG fusion protein can initiate neoplasia from lineage-committed haematopoietic cells.
Volume: 3
Issue: 8
Pages: e242
Publication
First Author: Li H
Year: 2007
Journal: J Clin Invest
Title: Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development.
Volume: 117
Issue: 5
Pages: 1314-23
Publication
First Author: Sohn EJ
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Accumulation of pre-let-7g and downregulation of mature let-7g with the depletion of EWS.
Volume: 426
Issue: 1
Pages: 89-93
Publication
First Author: Hume DA
Year: 2008
Journal: J Immunol
Title: The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene.
Volume: 180
Issue: 10
Pages: 6733-42
Publication
First Author: Kim KY
Year: 2014
Journal: Cell Death Differ
Title: A multifunctional protein EWS regulates the expression of Drosha and microRNAs.
Volume: 21
Issue: 1
Pages: 136-45
GXD Expression      
Probe: MGI:2667637
Assay Type: Western blot
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2667646
Age: postnatal adult
Specimen Label: Muscle
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2667637
Assay Type: Western blot
Annotation Date: 2003-07-29
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2667646
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2667637
Assay Type: Western blot
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2667646
Age: postnatal adult
Specimen Label: Thymus
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2667637
Assay Type: Western blot
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2667646
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2667637
Assay Type: Western blot
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2667646
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2667637
Assay Type: Western blot
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2667646
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2667637
Assay Type: Western blot
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:2667646
Age: postnatal adult
Specimen Label: Cerebellum
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2667637
Assay Type: Western blot
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2667646
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:2667637
Assay Type: Western blot
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2667646
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:2667637
Assay Type: Western blot
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2667646
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:2667637
Assay Type: Western blot
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2667651
Age: postnatal adult
Specimen Label: Adult Brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2667637
Assay Type: Western blot
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2667651
Age: postnatal newborn
Specimen Label: PN Brain
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2667642
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2667656
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2667642
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2667656
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2667642
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2667656
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2667642
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:2667660
Age: embryonic day 11.5
Specimen Label: E11.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2667642
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Stage: TS20
Assay Id: MGI:2667660
Age: embryonic day 12.5
Specimen Label: E12.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2667642
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:2667660
Age: embryonic day 13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2667642
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:2667660
Age: embryonic day 14.5
Specimen Label: E14.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2667642
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:2667660
Age: embryonic day 15.5
Specimen Label: E15.5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2667642
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:2667660
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2667642
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:2667660
Age: embryonic day 17.5
Specimen Label: E17.5
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2667642
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2667660
Age: postnatal newborn
Specimen Label: PN
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:2667642
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2667660
Age: postnatal adult
Specimen Label: adult
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:2667643
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:2667661
Age: embryonic day 11.5
Specimen Label: E11.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2667643
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Stage: TS20
Assay Id: MGI:2667661
Age: embryonic day 12.5
Specimen Label: E12.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2667643
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:2667661
Age: embryonic day 13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2667643
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:2667661
Age: embryonic day 14.5
Specimen Label: E14.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2667643
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:2667661
Age: embryonic day 15.5
Specimen Label: E15.5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2667643
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:2667661
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2667643
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:2667661
Age: embryonic day 17.5
Specimen Label: E17.5
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2667643
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2667661
Age: postnatal newborn
Specimen Label: PN
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:2667643
Assay Type: RT-PCR
Annotation Date: 2003-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2667661
Age: postnatal adult
Specimen Label: adult
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:464795
Assay Type: Northern blot
Annotation Date: 2005-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:3604360
Age: embryonic day 7.0
Specimen Label: 7
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:464795
Assay Type: Northern blot
Annotation Date: 2005-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:3604360
Age: embryonic day 11.0
Specimen Label: 11
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:464795
Assay Type: Northern blot
Annotation Date: 2005-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3604360
Age: embryonic day 15.0
Specimen Label: 15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:464795
Assay Type: Northern blot
Annotation Date: 2005-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3604360
Age: embryonic day 17.0
Specimen Label: 17
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3614792
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3616650
Age: embryonic day 13.5
Specimen Label: RT-PCR E13.5 brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3614792
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3616650
Age: postnatal day 0
Specimen Label: RT-PCR P0 brain
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2667637
Assay Type: Western blot
Annotation Date: 2009-05-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3845540
Age: postnatal adult
Specimen Label: not shown
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2667637
Assay Type: Western blot
Annotation Date: 2009-05-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737327
Stage: TS27
Assay Id: MGI:3845540
Age: postnatal newborn
Specimen Label: not shown
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2667637
Assay Type: Western blot
Annotation Date: 2009-05-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3845540
Age: postnatal adult
Specimen Label: not shown
Detected: true
Specimen Num: 3