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Search results 1 to 100 out of 289 for Ezh1

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Type Details Score
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: human
Protein Domain
Type: Family
Description: The Polycomb Repressive Complex 2 (PRC2) is a chromatin modifying complex that consists of three core components: EED, SUZ12 and one of the two histone H3K27 methyltransferases, EZH1 or EZH2 []. The PRC2 complex catalyses di- and trimethylation of histone H3 lysine 27 (H3K37me2/3), which has a repressive role. Even though EZH1 and EZH2 form similar PRC2 complexes, they exhibit contrasting repressive roles. In terms of their expression in mice, EZH1 is more abundant in nonproliferative adult organs, while EZH2 expression is tightly associated with proliferation [].This family consists of EZH1 [].
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Shen X
Year: 2008
Journal: Mol Cell
Title: EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency.
Volume: 32
Issue: 4
Pages: 491-502
Publication
First Author: Margueron R
Year: 2008
Journal: Mol Cell
Title: Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms.
Volume: 32
Issue: 4
Pages: 503-18
Protein
Organism: Mus musculus/domesticus
Length: 747  
Fragment?: false
Publication
First Author: Zhang Y
Year: 2014
Journal: Blood
Title: The polycomb repressive complex 2 governs life and death of peripheral T cells.
Volume: 124
Issue: 5
Pages: 737-49
Protein
Organism: Mus musculus/domesticus
Length: 750  
Fragment?: false
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Laible G
Year: 1999
Journal: Mamm Genome
Title: The murine polycomb-group genes Ezh1 and Ezh2 map close to Hox gene clusters on mouse chromosomes 11 and 6.
Volume: 10
Issue: 3
Pages: 311-4
Publication
First Author: Arai D
Year: 2010
Journal: Dev Biol
Title: Polycomb group protein Ezh1 represses Nodal and maintains the left-right axis.
Volume: 341
Issue: 2
Pages: 459-63
Publication
First Author: Ai S
Year: 2017
Journal: Circ Res
Title: Divergent Requirements for EZH1 in Heart Development Versus Regeneration.
Volume: 121
Issue: 2
Pages: 106-112
Publication  
First Author: Aoyama K
Year: 2018
Journal: iScience
Title: Ezh1 Targets Bivalent Genes to Maintain Self-Renewing Stem Cells in Ezh2-Insufficient Myelodysplastic Syndrome.
Volume: 9
Pages: 161-174
Publication
First Author: Mu W
Year: 2017
Journal: Dev Biol
Title: EZH1 in germ cells safeguards the function of PRC2 during spermatogenesis.
Volume: 424
Issue: 2
Pages: 198-207
Publication
First Author: Hidalgo I
Year: 2012
Journal: Cell Stem Cell
Title: Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest.
Volume: 11
Issue: 5
Pages: 649-62
Publication
First Author: Son J
Year: 2013
Journal: Genes Dev
Title: Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin.
Volume: 27
Issue: 24
Pages: 2663-77
Publication  
First Author: Lui JC
Year: 2016
Journal: Nat Commun
Title: EZH1 and EZH2 promote skeletal growth by repressing inhibitors of chondrocyte proliferation and hypertrophy.
Volume: 7
Pages: 13685
Publication  
First Author: Henriquez B
Year: 2013
Journal: Mol Cell Neurosci
Title: Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in developing hippocampal neurons.
Volume: 57
Pages: 130-43
Publication
First Author: Bardot ES
Year: 2013
Journal: EMBO J
Title: Polycomb subunits Ezh1 and Ezh2 regulate the Merkel cell differentiation program in skin stem cells.
Volume: 32
Issue: 14
Pages: 1990-2000
Publication
First Author: Lau-Corona D
Year: 2020
Journal: PLoS Genet
Title: Sex-biased genetic programs in liver metabolism and liver fibrosis are controlled by EZH1 and EZH2.
Volume: 16
Issue: 5
Pages: e1008796
Publication
First Author: Ezhkova E
Year: 2011
Journal: Genes Dev
Title: EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair.
Volume: 25
Issue: 5
Pages: 485-98
Publication
First Author: Laible G
Year: 1997
Journal: EMBO J
Title: Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres.
Volume: 16
Issue: 11
Pages: 3219-32
Publication
First Author: Grindheim JM
Year: 2019
Journal: Gastroenterology
Title: Polycomb Repressive Complex 2 Proteins EZH1 and EZH2 Regulate Timing of Postnatal Hepatocyte Maturation and Fibrosis by Repressing Genes With Euchromatic Promoters in Mice.
Volume: 156
Issue: 6
Pages: 1834-1848
Publication
First Author: Ogawa M
Year: 1998
Journal: Biochim Biophys Acta
Title: Cloning and expression of a human/mouse Polycomb group gene, ENX-2/Enx-2.
Volume: 1395
Issue: 2
Pages: 151-8
Publication
First Author: Ragazzini R
Year: 2019
Journal: Nat Commun
Title: EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells.
Volume: 10
Issue: 1
Pages: 3858
Publication
First Author: Walker E
Year: 2010
Journal: Cell Stem Cell
Title: Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation.
Volume: 6
Issue: 2
Pages: 153-66
Publication
First Author: Mochizuki-Kashio M
Year: 2015
Journal: Blood
Title: Ezh2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an Ezh1-dependent manner.
Volume: 126
Issue: 10
Pages: 1172-83
Publication
First Author: Bae WK
Year: 2015
Journal: FASEB J
Title: The methyltransferases enhancer of zeste homolog (EZH) 1 and EZH2 control hepatocyte homeostasis and regeneration.
Volume: 29
Issue: 5
Pages: 1653-62
Publication
First Author: Mochizuki-Kashio M
Year: 2011
Journal: Blood
Title: Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells.
Volume: 118
Issue: 25
Pages: 6553-61
Publication
First Author: Vo LT
Year: 2018
Journal: Nature
Title: Regulation of embryonic haematopoietic multipotency by EZH1.
Volume: 553
Issue: 7689
Pages: 506-510
Publication
First Author: Abel KJ
Year: 1996
Journal: Genomics
Title: Characterization of EZH1, a human homolog of Drosophila Enhancer of zeste near BRCA1.
Volume: 37
Issue: 2
Pages: 161-71
Publication
First Author: Aoyama K
Year: 2021
Journal: Leukemia
Title: PRC2 insufficiency causes p53-dependent dyserythropoiesis in myelodysplastic syndrome.
Volume: 35
Issue: 4
Pages: 1156-1165
Publication  
First Author: Zhao Y
Year: 2022
Journal: Development
Title: Maternal Ezh1/2 deficiency in oocyte delays H3K27me2/3 restoration and impairs epiblast development responsible for embryonic sub-lethality in mouse.
Volume: 149
Issue: 15
Publication
First Author: Ehringer MA
Year: 2001
Journal: Mamm Genome
Title: High-throughput sequence identification of gene coding variants within alcohol-related QTLs.
Volume: 12
Issue: 8
Pages: 657-63
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:2655188
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2655713
Age: embryonic day 7.0
Specimen Label: E7
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2655188
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2655713
Age: embryonic day 11.0
Specimen Label: E11
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2655188
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2655713
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2655188
Assay Type: Northern blot
Annotation Date: 2003-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2655713
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2657030
Assay Type: Northern blot
Annotation Date: 2003-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2657034
Age: postnatal adult
Specimen Label: KI
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2657032
Assay Type: RNase protection
Annotation Date: 2003-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:2657036
Age: embryonic day 9.5
Specimen Label: E9.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2657032
Assay Type: RNase protection
Annotation Date: 2003-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:2657036
Age: embryonic day 13.0
Specimen Label: E13 FL
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2657032
Assay Type: RNase protection
Annotation Date: 2003-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:2657036
Age: embryonic day 13.0
Specimen Label: E13 BR
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2657032
Assay Type: RNase protection
Annotation Date: 2003-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598821
Stage: TS21
Assay Id: MGI:2657036
Age: embryonic day 13.0
Specimen Label: E13 SM
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2657032
Assay Type: RNase protection
Annotation Date: 2003-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684625
Stage: TS25
Assay Id: MGI:2657036
Age: embryonic day 17.0
Specimen Label: E17 FL
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2657032
Assay Type: RNase protection
Annotation Date: 2003-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:2657036
Age: embryonic day 17.0
Specimen Label: E17 BR
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:2657032
Assay Type: RNase protection
Annotation Date: 2003-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598825
Stage: TS25
Assay Id: MGI:2657036
Age: embryonic day 17.0
Specimen Label: E17 SM
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:2657032
Assay Type: RNase protection
Annotation Date: 2003-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2657036
Age: postnatal week 6-8
Specimen Label: adult KI
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:2657032
Assay Type: RNase protection
Annotation Date: 2003-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2657036
Age: postnatal week 6-8
Specimen Label: adult SP
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:2657032
Assay Type: RNase protection
Annotation Date: 2003-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2657036
Age: postnatal week 6-8
Specimen Label: adult LI
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:2657032
Assay Type: RNase protection
Annotation Date: 2003-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2657036
Age: postnatal week 6-8
Specimen Label: adult TH
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:2657032
Assay Type: RNase protection
Annotation Date: 2003-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2657036
Age: postnatal week 6-8
Specimen Label: adult BR
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:2657032
Assay Type: RNase protection
Annotation Date: 2003-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2657036
Age: postnatal week 6-8
Specimen Label: adult SM
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:3521650
Assay Type: RT-PCR
Annotation Date: 2005-01-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1675215
Stage: TS15
Assay Id: MGI:3521695
Age: embryonic day 9.5
Image: 3
Specimen Label: PSM
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3521650
Assay Type: RT-PCR
Annotation Date: 2005-01-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618415
Stage: TS15
Assay Id: MGI:3521695
Age: embryonic day 9.5
Image: 3
Specimen Label: SOM
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6266934
Assay Type: RT-PCR
Annotation Date: 2018-12-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608517
Stage: TS17
Assay Id: MGI:6266940
Age: embryonic day 10.5
Image: 4
Specimen Label: YS
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:2663457
Age: embryonic day 4.0
Specimen Label: B
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:2663457
Age: embryonic day 7.3
Specimen Label: 7.3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603916
Stage: TS16
Assay Id: MGI:2663457
Age: embryonic day 10.0
Specimen Label: 10
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:2663457
Age: embryonic day 12.0
Specimen Label: 12
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:2663457
Age: embryonic day 14.0
Specimen Label: 14
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185824
Stage: TS24
Assay Id: MGI:2663457
Age: embryonic day 16.0
Specimen Label: 16h
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185724
Stage: TS24
Assay Id: MGI:2663457
Age: embryonic day 16.0
Specimen Label: 16b
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185826
Stage: TS26
Assay Id: MGI:2663457
Age: embryonic day 18.0
Specimen Label: 18h
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185726
Stage: TS26
Assay Id: MGI:2663457
Age: embryonic day 18.0
Specimen Label: 18b
Detected: true
Specimen Num: 10
GXD Expression        
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:2663457
Age: postnatal adult
Specimen Label: Co
Specimen Num: 12
GXD Expression        
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2663457
Age: postnatal adult
Specimen Label: He
Specimen Num: 13
GXD Expression        
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2663457
Age: postnatal adult
Specimen Label: Br
Specimen Num: 14
GXD Expression        
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2663457
Age: postnatal adult
Specimen Label: Li
Specimen Num: 15
GXD Expression      
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2663457
Age: postnatal adult
Specimen Label: Lu
Detected: true
Specimen Num: 16
GXD Expression      
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3552328
Stage: TS28
Assay Id: MGI:2663457
Age: postnatal adult
Specimen Label: Ln
Detected: true
Specimen Num: 17
GXD Expression      
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2663457
Age: postnatal adult
Specimen Label: Sp
Detected: true
Specimen Num: 18
GXD Expression      
Probe: MGI:2663300
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2663457
Age: postnatal adult
Specimen Label: Ki
Detected: true
Specimen Num: 19