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Search results 1 to 100 out of 313 for F8

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
2157 | F8
Type: gene
Organism: human
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Gene
100493411 | f8
Type: gene
Organism: frog, western clawed
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Gene
302470 | F8
Type: gene
Organism: rat
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Gene
473838 | F8
Type: gene
Organism: chimpanzee
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Gene
403875 | F8
Type: gene
Organism: dog, domestic
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Gene
100271720 | F8
Type: gene
Organism: cattle
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Gene
422199 | F8
Type: gene
Organism: chicken
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Gene
100302404 | f8
Type: gene
Organism: zebrafish
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Gene
100424151 | F8
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:88383 | F8
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
108004545 | LOC108004545
Type: gene
Organism: human
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Allele
f8ga | MGI:3578532
 
Name: f8 gastrulation arrest
Allele Type: Chemically induced (ENU)
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Publication
31843008 | J:285277
First Author: Zhang JP
Year: 2019
Journal: Genome Biol
Title: Curing hemophilia A by NHEJ-mediated ectopic F8 insertion in the mouse.
Volume: 20
Issue: 1
Pages: 276
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Cell Line
Cell Line
Name: F8
Derivation . Parent Cell Line . Name: D3H
Cell Line Type: ES Cell
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Publication
26588198 | J:266699
First Author: Chao BN
Year: 2016
Journal: J Thromb Haemost
Title: Characterization of a genetically engineered mouse model of hemophilia A with complete deletion of the F8 gene.
Volume: 14
Issue: 2
Pages: 346-55
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Heritable Phenotypic Marker
MGI:3578179 | f8ga
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
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Protein Domain
IPR008726 | Poxvirus_F8
Type: Family
Description: This family consists of several poxvirus F8 proteins. The function of this family is unknown.
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GXD Expression
GXD Expression
     
Probe: MGI:2179073
Assay Type: RT-PCR
Annotation Date: 2002-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:2179079
Age: embryonic day 7.5
Specimen Label: F8
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2179073
Assay Type: RT-PCR
Annotation Date: 2002-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2179080
Age: postnatal adult
Specimen Label: F8
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2681703
Assay Type: RT-PCR
Annotation Date: 2003-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:2681778
Age: postnatal day 21
Specimen Label: F8
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:2681702
Assay Type: RT-PCR
Annotation Date: 2003-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:2681779
Age: postnatal day 21
Specimen Label: F8
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:2681701
Assay Type: RT-PCR
Annotation Date: 2003-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:2681780
Age: postnatal day 21
Specimen Label: F8
Detected: true
Specimen Num: 6
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Publication
34290295 | J:313828
First Author: Hayakawa M
Year: 2021
Journal: Sci Rep
Title: Characterization and visualization of murine coagulation factor VIII-producing cells in vivo.
Volume: 11
Issue: 1
Pages: 14824
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Publication
21705497 | J:176909
First Author: van Helden PM
Year: 2011
Journal: Blood
Title: Maintenance and break of immune tolerance against human factor VIII in a new transgenic hemophilic mouse model.
Volume: 118
Issue: 13
Pages: 3698-707
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Publication
20852129 | J:167399
First Author: Greene TK
Year: 2010
Journal: Blood
Title: In vivo efficacy of platelet-delivered, high specific activity factor VIII variants.
Volume: 116
Issue: 26
Pages: 6114-22
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Gene
100537224 | adgrf8
Type: gene
Organism: zebrafish
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Publication
24719406 | J:213133
First Author: Everett LA
Year: 2014
Journal: Blood
Title: Murine coagulation factor VIII is synthesized in endothelial cells.
Volume: 123
Issue: 24
Pages: 3697-705
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Publication
28827327 | J:244506
First Author: Westrick RJ
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Sensitized mutagenesis screen in Factor V Leiden mice identifies thrombosis suppressor loci.
Volume: 114
Issue: 36
Pages: 9659-9664
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Protein
B7ZNH8
Organism: Mus musculus/domesticus
Length: 2247  
Fragment?: false
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Protein
B2RRC9
Organism: Mus musculus/domesticus
Length: 2249  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0033194 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035856 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035843 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035764 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035825 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035535 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_88383 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0036355 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034821 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035508 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035666 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035607 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035748 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035641 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0036381 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034518 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034960 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031738 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0034354 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
8314577 | J:4959
First Author: Elder B
Year: 1993
Journal: Genomics
Title: Sequence of the murine factor VIII cDNA.
Volume: 16
Issue: 2
Pages: 374-9
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Publication
22368271 | J:186576
First Author: Follenzi A
Year: 2012
Journal: Blood
Title: Role of bone marrow transplantation for correcting hemophilia A in mice.
Volume: 119
Issue: 23
Pages: 5532-42
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Publication
7647782 | J:24941
First Author: Bi L
Year: 1995
Journal: Nat Genet
Title: Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A.
Volume: 10
Issue: 1
Pages: 119-21
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Publication
21788339 | J:177079
First Author: Pordes AG
Year: 2011
Journal: Blood
Title: T cell-independent restimulation of FVIII-specific murine memory B cells is facilitated by dendritic cells together with toll-like receptor 7 agonist.
Volume: 118
Issue: 11
Pages: 3154-62
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Publication
26668132 | J:232594
First Author: Chen Y
Year: 2016
Journal: Blood
Title: The immunogenicity of platelet-derived FVIII in hemophilia A mice with or without preexisting anti-FVIII immunity.
Volume: 127
Issue: 10
Pages: 1346-54
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Publication
20889922 | J:170788
First Author: Allacher P
Year: 2011
Journal: Blood
Title: Stimulation and inhibition of FVIII-specific memory B-cell responses by CpG-B (ODN 1826), a ligand for Toll-like receptor 9.
Volume: 117
Issue: 1
Pages: 259-67
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Publication
29109275 | J:254329
First Author: Nielsen AL
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Engineering of a membrane-triggered activity switch in coagulation factor VIIa.
Volume: 114
Issue: 47
Pages: 12454-12459
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Publication
18495954 | J:140154
First Author: Shi Q
Year: 2008
Journal: Blood
Title: Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity.
Volume: 112
Issue: 7
Pages: 2713-21
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Publication
27034428 | J:234697
First Author: Lai JD
Year: 2016
Journal: Blood
Title: Concurrent influenza vaccination reduces anti-FVIII antibody responses in murine hemophilia A.
Volume: 127
Issue: 26
Pages: 3439-49
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Publication
10557319 | J:58518
First Author: Lipshutz GS
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Short-term correction of factor VIII deficiency in a murine model of hemophilia A after delivery of adenovirus murine factor VIII in utero.
Volume: 96
Issue: 23
Pages: 13324-9
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Publication
8896409 | J:36698
First Author: Bi L
Year: 1996
Journal: Blood
Title: Further characterization of factor VIII-deficient mice created by gene targeting: RNA and protein studies.
Volume: 88
Issue: 9
Pages: 3446-50
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Publication
21041718 | J:168395
First Author: Ward NJ
Year: 2011
Journal: Blood
Title: Codon optimization of human factor VIII cDNAs leads to high-level expression.
Volume: 117
Issue: 3
Pages: 798-807
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Publication
22498747 | J:185146
First Author: Wroblewska A
Year: 2012
Journal: Blood
Title: Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice.
Volume: 119
Issue: 22
Pages: 5294-300
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Publication
22394599 | J:183893
First Author: Steinitz KN
Year: 2012
Journal: Blood
Title: CD4+ T-cell epitopes associated with antibody responses after intravenously and subcutaneously applied human FVIII in humanized hemophilic E17 HLA-DRB1*1501 mice.
Volume: 119
Issue: 17
Pages: 4073-82
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Publication
10666206 | J:110275
First Author: Qian J
Year: 2000
Journal: Blood
Title: Prevention and treatment of factor VIII inhibitors in murine hemophilia A.
Volume: 95
Issue: 4
Pages: 1324-9
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Publication
29395036 | J:306010
 
First Author: Peyron I
Year: 2018
Journal: Cell Immunol
Title: Oxidation of factor VIII increases its immunogenicity in mice with severe hemophilia A.
Volume: 325
Pages: 64-68
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Publication
25534204 | J:230274
First Author: Bhatt S
Year: 2015
Journal: Exp Hematol
Title: Hepatic stellate cell-conditioned myeloid cells provide a novel therapy for prevention of factor VIII antibody formation in mice.
Volume: 43
Issue: 4
Pages: 277-85
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Publication
22655063 | J:187309
First Author: Sack BK
Year: 2012
Journal: PLoS One
Title: Transient B cell depletion or improved transgene expression by codon optimization promote tolerance to factor VIII in gene therapy.
Volume: 7
Issue: 5
Pages: e37671
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Publication
22031860 | J:181577
First Author: Milanov P
Year: 2012
Journal: Blood
Title: Engineered factor IX variants bypass FVIII and correct hemophilia A phenotype in mice.
Volume: 119
Issue: 2
Pages: 602-11
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Publication
23426947 | J:196695
First Author: McIntosh J
Year: 2013
Journal: Blood
Title: Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant.
Volume: 121
Issue: 17
Pages: 3335-44
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Publication
25849132 | J:228247
First Author: Sehgal A
Year: 2015
Journal: Nat Med
Title: An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia.
Volume: 21
Issue: 5
Pages: 492-7
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Publication
10779424 | J:61846
First Author: Fakharzadeh SS
Year: 2000
Journal: Blood
Title: Correction of the coagulation defect in hemophilia A mice through factor VIII expression in skin.
Volume: 95
Issue: 9
Pages: 2799-805
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Publication
35821634 | J:349023
First Author: Butterfield JSS
Year: 2022
Journal: Mol Ther
Title: IL-15 blockade and rapamycin rescue multifactorial loss of factor VIII from AAV-transduced hepatocytes in hemophilia A mice.
Volume: 30
Issue: 12
Pages: 3552-3569
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Publication
19458355 | J:150739
First Author: Matsui H
Year: 2009
Journal: Blood
Title: A murine model for induction of long-term immunologic tolerance to factor VIII does not require persistent detectable levels of plasma factor VIII and involves contributions from Foxp3+ T regulatory cells.
Volume: 114
Issue: 3
Pages: 677-85
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Publication
30064978 | J:265977
First Author: Muczynski V
Year: 2018
Journal: Blood
Title: A factor VIII-nanobody fusion protein forming an ultrastable complex with VWF: effect on clearance and antibody formation.
Volume: 132
Issue: 11
Pages: 1193-1197
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Publication
25126862 | J:221006
First Author: Matsui H
Year: 2014
Journal: PLoS One
Title: Delivery of full-length factor VIII using a piggyBac transposon vector to correct a mouse model of hemophilia A.
Volume: 9
Issue: 8
Pages: e104957
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Publication
28837614 | J:248312
First Author: Kiouptsi K
Year: 2017
Journal: PLoS One
Title: Mice deficient in the anti-haemophilic coagulation factor VIII show increased von Willebrand factor plasma levels.
Volume: 12
Issue: 8
Pages: e0183590
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Publication
29656466 | J:271959
First Author: Mishra A
Year: 2018
Journal: Int J Exp Pathol
Title: Evaluation of high-fat high-fructose diet treatment in factor VIII (coagulation factor)-deficient mouse model.
Volume: 99
Issue: 1
Pages: 46-53
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Publication
19139414 | J:143861
First Author: Xu D
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Phenotypic correction of murine hemophilia A using an iPS cell-based therapy.
Volume: 106
Issue: 3
Pages: 808-13
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Publication
26825708 | J:232631
First Author: Eubanks J
Year: 2016
Journal: Blood
Title: A subset of high-titer anti-factor VIII A2 domain antibodies is responsive to treatment with factor VIII.
Volume: 127
Issue: 16
Pages: 2028-34
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Publication
23372167 | J:197469
First Author: Siner JI
Year: 2013
Journal: Blood
Title: Minimal modification in the factor VIII B-domain sequence ameliorates the murine hemophilia A phenotype.
Volume: 121
Issue: 21
Pages: 4396-403
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Publication
35143636 | J:326166
First Author: Magisetty J
Year: 2022
Journal: Blood
Title: Selective inhibition of activated protein C anticoagulant activity protects against hemophilic arthropathy in mice.
Volume: 139
Issue: 18
Pages: 2830-2841
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Publication
30021767 | J:264325
First Author: Zhang AH
Year: 2018
Journal: J Immunol
Title: Targeting Antigen-Specific B Cells Using Antigen-Expressing Transduced Regulatory T Cells.
Volume: 201
Issue: 5
Pages: 1434-1441
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Publication
37116753 | J:340101
First Author: Cooke EJ
Year: 2023
Journal: J Thromb Haemost
Title: Maladaptive lymphangiogenesis is associated with synovial iron accumulation and delayed clearance in factor VIII-deficient mice after induced hemarthrosis.
Volume: 21
Issue: 9
Pages: 2390-2404
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Publication
19463774 | J:151239
First Author: Ragni MV
Year: 2009
Journal: Exp Hematol
Title: Factor VIII-pulsed dendritic cells reduce anti-factor VIII antibody formation in the hemophilia A mouse model.
Volume: 37
Issue: 6
Pages: 744-54
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Publication
26775174 | J:234667
 
First Author: Krishnamoorthy S
Year: 2016
Journal: Cell Immunol
Title: Recombinant factor VIII Fc (rFVIIIFc) fusion protein reduces immunogenicity and induces tolerance in hemophilia A mice.
Volume: 301
Pages: 30-9
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Publication
26687613 | J:234671
 
First Author: Zhang AH
Year: 2016
Journal: Cell Immunol
Title: Tolerogenic nanoparticles to induce immunologic tolerance: Prevention and reversal of FVIII inhibitor formation.
Volume: 301
Pages: 74-81
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Publication
35595575 | J:332201
 
First Author: Mashausi DS
Year: 2022
Journal: Biochem Biophys Res Commun
Title: A high efficient FVIII variant corrects bleeding in hemophilia A mouse model.
Volume: 637
Pages: 358-364
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Publication
25331117 | J:220788
First Author: Leong L
Year: 2015
Journal: Blood
Title: Noncovalent stabilization of the factor VIII A2 domain enhances efficacy in hemophilia A mouse vascular injury models.
Volume: 125
Issue: 2
Pages: 392-8
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Publication
27144769 | J:252467
First Author: Staber JM
Year: 2016
Journal: PLoS One
Title: Shortened Lifespan and Lethal Hemorrhage in a Hemophilia A Mouse Model.
Volume: 11
Issue: 5
Pages: e0154857
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Publication
15576475 | J:105059
First Author: Ohlfest JR
Year: 2005
Journal: Blood
Title: Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system.
Volume: 105
Issue: 7
Pages: 2691-8
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Publication
11313267 | J:70448
First Author: Rossi G
Year: 2001
Journal: Blood
Title: Long-term induction of immune tolerance after blockade of CD40-CD40L interaction in a mouse model of hemophilia A.
Volume: 97
Issue: 9
Pages: 2750-7
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Publication
15728582 | J:99097
First Author: Purohit VS
Year: 2005
Journal: J Biol Chem
Title: Lower inhibitor development in hemophilia A mice following administration of recombinant factor VIII-O-phospho-L-serine complex.
Volume: 280
Issue: 18
Pages: 17593-600
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Publication
24825864 | J:214325
First Author: Sherman A
Year: 2014
Journal: Blood
Title: Suppression of inhibitor formation against FVIII in a murine model of hemophilia A by oral delivery of antigens bioencapsulated in plant cells.
Volume: 124
Issue: 10
Pages: 1659-68
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Publication
32369559 | J:304769
First Author: Ferrière S
Year: 2020
Journal: Blood
Title: A hemophilia A mouse model for the in vivo assessment of emicizumab function.
Volume: 136
Issue: 6
Pages: 740-748
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Publication
18815284 | J:144256
First Author: Waters B
Year: 2009
Journal: Blood
Title: Anti-CD3 prevents factor VIII inhibitor development in hemophilia A mice by a regulatory CD4+CD25+-dependent mechanism and by shifting cytokine production to favor a Th1 response.
Volume: 113
Issue: 1
Pages: 193-203
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Publication
23231432 | J:195442
First Author: Sen D
Year: 2013
Journal: J Thromb Haemost
Title: Nuclear factor (NF)-κB and its associated pathways are major molecular regulators of blood-induced joint damage in a murine model of hemophilia.
Volume: 11
Issue: 2
Pages: 293-306
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Publication
16493498 | J:178969
First Author: Bril WS
Year: 2006
Journal: Thromb Haemost
Title: Tolerance to factor VIII in a transgenic mouse expressing human factor VIII cDNA carrying an Arg(593) to Cys substitution.
Volume: 95
Issue: 2
Pages: 341-7
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Publication
9576953 | J:47661
First Author: Evans GL
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Genetic induction of immune tolerance to human clotting factor VIII in a mouse model for hemophilia A.
Volume: 95
Issue: 10
Pages: 5734-9
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Publication
24358271 | J:209857
First Author: Tatsumi K
Year: 2013
Journal: PLoS One
Title: A novel cell-sheet technology that achieves durable factor VIII delivery in a mouse model of hemophilia A.
Volume: 8
Issue: 12
Pages: e83280
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Publication
18559671 | J:139175
First Author: Neyman M
Year: 2008
Journal: Blood
Title: Analysis of the spatial and temporal characteristics of platelet-delivered factor VIII-based clots.
Volume: 112
Issue: 4
Pages: 1101-8
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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