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Search results 1 to 100 out of 362 for Faah

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
2166 | FAAH
Type: gene
Organism: human
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Gene
540007 | FAAH
Type: gene
Organism: cattle
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Gene
100911581 | Faah
Type: gene
Organism: rat
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Gene
424614 | FAAH
Type: gene
Organism: chicken
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Gene
569067 | faah
Type: gene
Organism: zebrafish
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Gene
708850 | FAAH
Type: gene
Organism: macaque, rhesus
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Gene
482510 | FAAH
Type: gene
Organism: dog, domestic
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Gene
456559 | FAAH
Type: gene
Organism: chimpanzee
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Protein Domain
IPR030560 | FAAH
Type: Family
Description: Fatty-acid amide hydrolase 1 (FAAH) is a mammalian integral membrane enzyme that degrades the fatty acid amide family of endogenous signalling lipids, which includes the endogenous cannabinoid anandamide and the sleep-inducing substance oleamide [].
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Protein Coding Gene
MGI:109609 | Faah
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:981324
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825839
Age: embryonic day 14.5
Image: Additional file 4 Faah
Specimen Label: Additional file 4 Faah
Detected: true
Specimen Num: 1
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Publication
25731744 | J:221783
 
First Author: Dincheva I
Year: 2015
Journal: Nat Commun
Title: FAAH genetic variation enhances fronto-amygdala function in mouse and human.
Volume: 6
Pages: 6395
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Publication
18987328 | J:146011
First Author: Sun X
Year: 2009
Journal: Biol Reprod
Title: Genetic loss of Faah compromises male fertility in mice.
Volume: 80
Issue: 2
Pages: 235-42
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Publication
16448676 | J:109633
First Author: Basavarajappa BS
Year: 2006
Journal: Neuropharmacology
Title: Increased ethanol consumption and preference and decreased ethanol sensitivity in female FAAH knockout mice.
Volume: 50
Issue: 7
Pages: 834-44
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Publication
22442717 | J:224207
First Author: Vaitheesvaran B
Year: 2012
Journal: PLoS One
Title: Peripheral effects of FAAH deficiency on fuel and energy homeostasis: role of dysregulated lysine acetylation.
Volume: 7
Issue: 3
Pages: e33717
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Publication
19918051 | J:155578
First Author: Long JZ
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo.
Volume: 106
Issue: 48
Pages: 20270-5
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Publication
15209515 | J:115495
First Author: Ortega-Gutiérrez S
Year: 2004
Journal: Biochemistry
Title: Comparison of anandamide transport in FAAH wild-type and knockout neurons: evidence for contributions by both FAAH and the CB1 receptor to anandamide uptake.
Volume: 43
Issue: 25
Pages: 8184-90
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Protein
O08914
Organism: Mus musculus/domesticus
Length: 579  
Fragment?: false
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Protein
Q8BRM1
Organism: Mus musculus/domesticus
Length: 745  
Fragment?: false
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Protein
Q8K4H2
Organism: Mus musculus/domesticus
Length: 65  
Fragment?: true
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Protein
Q8C541
Organism: Mus musculus/domesticus
Length: 579  
Fragment?: false
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Protein
Q3UUF0
Organism: Mus musculus/domesticus
Length: 534  
Fragment?: true
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Publication
15952893 | -
 
First Author: McKinney MK
Year: 2005
Journal: Annu Rev Biochem
Title: Structure and function of fatty acid amide hydrolase.
Volume: 74
Pages: 411-32
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GXD Expression
GXD Expression
   
Probe: MGI:6172371
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190248
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Faah
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6172371
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190248
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Faah
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6172371
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190248
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Faah
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6172371
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190248
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Faah
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6172371
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190248
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Faah
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6172371
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190248
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Faah
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6172371
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190248
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Faah
Detected: true
Specimen Num: 7
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Publication
9122178 | J:39332
First Author: Giang DK
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Molecular characterization of human and mouse fatty acid amide hydrolases.
Volume: 94
Issue: 6
Pages: 2238-42
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Publication
15533037 | J:94013
First Author: Saghatelian A
Year: 2004
Journal: Biochemistry
Title: Assignment of endogenous substrates to enzymes by global metabolite profiling.
Volume: 43
Issue: 45
Pages: 14332-9
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Publication
32095523 | J:287149
First Author: Burgdorf CE
Year: 2020
Journal: Sci Adv
Title: Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice.
Volume: 6
Issue: 7
Pages: eaay1502
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Publication
22912404 | J:189878
First Author: Brown WH
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism.
Volume: 109
Issue: 37
Pages: 14966-71
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Publication
24215562 | J:208387
First Author: Dainese E
Year: 2014
Journal: Biochem J
Title: Membrane lipids are key modulators of the endocannabinoid-hydrolase FAAH.
Volume: 457
Issue: 3
Pages: 463-72
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Publication
16571781 | J:111498
First Author: Bilsland LG
Year: 2006
Journal: FASEB J
Title: Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice.
Volume: 20
Issue: 7
Pages: 1003-5
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Publication
28749428 | J:326319
 
First Author: Helfand AI
Year: 2017
Journal: Int J Mol Sci
Title: Cannabinoid Receptor 1 and Fatty Acid Amide Hydrolase Contribute to Operant Sensation Seeking in Mice.
Volume: 18
Issue: 8
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Publication
26362942 | J:232248
First Author: Vázquez C
Year: 2015
Journal: Neurobiol Aging
Title: Endocannabinoid regulation of amyloid-induced neuroinflammation.
Volume: 36
Issue: 11
Pages: 3008-3019
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Publication
27001846 | J:232134
First Author: Gee DG
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Individual differences in frontolimbic circuitry and anxiety emerge with adolescent changes in endocannabinoid signaling across species.
Volume: 113
Issue: 16
Pages: 4500-5
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Publication
11470906 | J:70666
First Author: Cravatt BF
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase.
Volume: 98
Issue: 16
Pages: 9371-6
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Publication
23241405 | J:216906
First Author: Lenglet S
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice.
Volume: 33
Issue: 2
Pages: 215-23
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Publication
16866345 | J:111608
First Author: Saghatelian A
Year: 2006
Journal: Biochemistry
Title: A FAAH-regulated class of N-acyl taurines that activates TRP ion channels.
Volume: 45
Issue: 30
Pages: 9007-15
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Publication
21070851 | J:167473
First Author: Mukhopadhyay P
Year: 2011
Journal: Free Radic Biol Med
Title: Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury.
Volume: 50
Issue: 1
Pages: 179-95
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Publication
15576840 | J:96690
First Author: Patel S
Year: 2005
Journal: J Lipid Res
Title: The postmortal accumulation of brain N-arachidonylethanolamine (anandamide) is dependent upon fatty acid amide hydrolase activity.
Volume: 46
Issue: 2
Pages: 342-9
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Publication
15157693 | J:102816
First Author: Lichtman AH
Year: 2004
Journal: Pain
Title: Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia.
Volume: 109
Issue: 3
Pages: 319-27
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Publication
25575795 | J:219741
 
First Author: Wang ZY
Year: 2015
Journal: Neurosci Lett
Title: Activation of cannabinoid receptor 1 inhibits increased bladder activity induced by nerve growth factor.
Volume: 589
Pages: 19-24
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Publication
16418162 | J:112211
First Author: Siegmund SV
Year: 2006
Journal: J Biol Chem
Title: Fatty acid amide hydrolase determines anandamide-induced cell death in the liver.
Volume: 281
Issue: 15
Pages: 10431-8
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Publication
28768662 | J:281386
First Author: Ahmad A
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: Stimulation of diuresis and natriuresis by renomedullary infusion of a dual inhibitor of fatty acid amide hydrolase and monoacylglycerol lipase.
Volume: 313
Issue: 5
Pages: F1068-F1076
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Publication
12736361 | J:85395
First Author: Clement AB
Year: 2003
Journal: J Neurosci
Title: Increased seizure susceptibility and proconvulsant activity of anandamide in mice lacking fatty acid amide hydrolase.
Volume: 23
Issue: 9
Pages: 3916-23
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Publication
16886060 | J:113105
First Author: Wang H
Year: 2006
Journal: J Clin Invest
Title: Fatty acid amide hydrolase deficiency limits early pregnancy events.
Volume: 116
Issue: 8
Pages: 2122-31
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Publication
21097653 | J:180845
First Author: Long JZ
Year: 2011
Journal: J Lipid Res
Title: An anatomical and temporal portrait of physiological substrates for fatty acid amide hydrolase.
Volume: 52
Issue: 2
Pages: 337-44
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Publication
15482903 | J:103496
First Author: Egertová M
Year: 2004
Journal: J Chem Neuroanat
Title: Fatty acid amide hydrolase in brain ventricular epithelium: mutually exclusive patterns of expression in mouse and rat.
Volume: 28
Issue: 3
Pages: 171-81
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Publication
17709120 | J:179568
First Author: Moreira FA
Year: 2008
Journal: Neuropharmacology
Title: Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors.
Volume: 54
Issue: 1
Pages: 141-50
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Publication
19524055 | J:154412
First Author: Wise LE
Year: 2009
Journal: Neurobiol Learn Mem
Title: Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task.
Volume: 92
Issue: 4
Pages: 597-601
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Publication
15821037 | J:100316
First Author: Pacher P
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: Hemodynamic profile, responsiveness to anandamide, and baroreflex sensitivity of mice lacking fatty acid amide hydrolase.
Volume: 289
Issue: 2
Pages: H533-41
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Publication
25534441 | J:230786
 
First Author: Ativie F
Year: 2015
Journal: Life Sci
Title: Enhanced microglial activity in FAAH(-/-) animals.
Volume: 138
Pages: 52-6
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Publication
18501510 | J:137058
First Author: Webb M
Year: 2008
Journal: Neurosci Lett
Title: Genetic deletion of Fatty Acid Amide Hydrolase results in improved long-term outcome in chronic autoimmune encephalitis.
Volume: 439
Issue: 1
Pages: 106-10
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Publication
15247426 | J:91564
First Author: Cravatt BF
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Functional disassociation of the central and peripheral fatty acid amide signaling systems.
Volume: 101
Issue: 29
Pages: 10821-6
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Publication
23570577 | J:198350
First Author: Rashid MA
Year: 2013
Journal: J Neurochem
Title: N-Docosahexaenoylethanolamine is a potent neurogenic factor for neural stem cell differentiation.
Volume: 125
Issue: 6
Pages: 869-84
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Publication
34375644 | J:313025
First Author: Yaghootfam C
Year: 2021
Journal: J Biol Chem
Title: Deletion of fatty acid amide hydrolase reduces lyso-sulfatide levels but exacerbates metachromatic leukodystrophy in mice.
Volume: 297
Issue: 3
Pages: 101064
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Publication
17434980 | J:126029
First Author: Bátkai S
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase.
Volume: 293
Issue: 2
Pages: H909-18
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Publication
27178246 | J:322104
   
First Author: Carey LM
Year: 2016
Journal: Mol Pain
Title: A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase.
Volume: 12
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Publication
29846106 | J:280717
First Author: Ahmad A
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Modulation of mean arterial pressure and diuresis by renomedullary infusion of a selective inhibitor of fatty acid amide hydrolase.
Volume: 315
Issue: 4
Pages: F967-F976
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Publication
28488728 | J:245655
First Author: Lin L
Year: 2017
Journal: J Neurochem
Title: Fatty acid amide hydrolase (FAAH) regulates hypercapnia/ischemia-induced increases in n-acylethanolamines in mouse brain.
Volume: 142
Issue: 5
Pages: 662-671
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Publication
10208977 | J:54459
First Author: Paria BC
Year: 1999
Journal: Biol Reprod
Title: Fatty-acid amide hydrolase is expressed in the mouse uterus and embryo during the periimplantation period.
Volume: 60
Issue: 5
Pages: 1151-7
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Publication
24167249 | J:202900
First Author: Wenzel D
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction.
Volume: 110
Issue: 46
Pages: 18710-5
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Publication
16143133 | J:104632
First Author: Capasso R
Year: 2005
Journal: Gastroenterology
Title: Fatty acid amide hydrolase controls mouse intestinal motility in vivo.
Volume: 129
Issue: 3
Pages: 941-51
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Publication
12065702 | J:125564
First Author: Lichtman AH
Year: 2002
Journal: J Pharmacol Exp Ther
Title: Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo.
Volume: 302
Issue: 1
Pages: 73-9
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Publication
17944864 | J:128913
First Author: Vinod KY
Year: 2008
Journal: J Neurochem
Title: Manipulation of fatty acid amide hydrolase functional activity alters sensitivity and dependence to ethanol.
Volume: 104
Issue: 1
Pages: 233-43
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Publication
26900150 | J:232718
First Author: Sun X
Year: 2016
Journal: J Biol Chem
Title: Sustained Endocannabinoid Signaling Compromises Decidual Function and Promotes Inflammation-induced Preterm Birth.
Volume: 291
Issue: 15
Pages: 8231-40
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Publication
28065729 | J:250924
First Author: Alhouayek M
Year: 2017
Journal: Biochim Biophys Acta
Title: N-acylethanolamine-hydrolyzing acid amidase and fatty acid amide hydrolase inhibition differentially affect N-acylethanolamine levels and macrophage activation.
Volume: 1862
Issue: 5
Pages: 474-484
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Publication
31740614 | J:282520
First Author: Grevengoed TJ
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis.
Volume: 116
Issue: 49
Pages: 24770-24778
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Publication
20484813 | J:161640
First Author: Freigang S
Year: 2010
Journal: J Clin Invest
Title: Fatty acid amide hydrolase shapes NKT cell responses by influencing the serum transport of lipid antigen in mice.
Volume: 120
Issue: 6
Pages: 1873-84
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Publication
29967158 | J:264211
First Author: Balsevich G
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Role for fatty acid amide hydrolase (FAAH) in the leptin-mediated effects on feeding and energy balance.
Volume: 115
Issue: 29
Pages: 7605-7610
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Publication
20862299 | J:165113
 
First Author: Mallet C
Year: 2010
Journal: PLoS One
Title: TRPV1 in brain is involved in acetaminophen-induced antinociception.
Volume: 5
Issue: 9
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Publication
27412859 | J:235151
First Author: Sasso O
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Endogenous N-acyl taurines regulate skin wound healing.
Volume: 113
Issue: 30
Pages: E4397-406
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Publication
27893106 | J:254677
First Author: Miller S
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Evidence for a GPR18 Role in Diurnal Regulation of Intraocular Pressure.
Volume: 57
Issue: 14
Pages: 6419-6426
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Publication
23806692 | J:205325
First Author: Siegmund SV
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Fatty acid amide hydrolase but not monoacyl glycerol lipase controls cell death induced by the endocannabinoid 2-arachidonoyl glycerol in hepatic cell populations.
Volume: 437
Issue: 1
Pages: 48-54
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Publication
22321194 | J:322090
First Author: Benito C
Year: 2012
Journal: Br J Pharmacol
Title: β-Amyloid exacerbates inflammation in astrocytes lacking fatty acid amide hydrolase through a mechanism involving PPAR-α, PPAR-γ and TRPV1, but not CB₁ or CB₂ receptors.
Volume: 166
Issue: 4
Pages: 1474-89
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Publication
27109320 | J:321479
 
First Author: Leishman E
Year: 2016
Journal: Pharmacol Res
Title: Broad impact of deleting endogenous cannabinoid hydrolyzing enzymes and the CB1 cannabinoid receptor on the endogenous cannabinoid-related lipidome in eight regions of the mouse brain.
Volume: 110
Pages: 159-172
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Publication
9878243 | J:52080
First Author: Wan M
Year: 1998
Journal: Genomics
Title: Conserved chromosomal location and genomic structure of human and mouse fatty-acid amide hydrolase genes and evaluation of clasper as a candidate neurological mutation.
Volume: 54
Issue: 3
Pages: 408-14
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Protein Coding Gene
MGP_CAROLIEiJ_G0026321 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028614 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028575 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028524 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028596 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0028310 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_109609 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029037 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027744 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0028277 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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•
•
•
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Protein Coding Gene
MGP_DBA2J_G0028425 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0028393 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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•
•
•
•
Protein Coding Gene
MGP_LPJ_G0028527 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0028420 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0029074 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0027470 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0027823 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0028653 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0027293 | -
Type: protein_coding_gene
Organism: Mus spretus
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•
•
•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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