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Search results 1 to 100 out of 349 for Fah

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
2184 | FAH
Type: gene
Organism: human
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Gene
467738 | FAH
Type: gene
Organism: chimpanzee
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Gene
508724 | FAH
Type: gene
Organism: cattle
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Gene
100855836 | FAH
Type: gene
Organism: dog, domestic
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Gene
415482 | FAH
Type: gene
Organism: chicken
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Gene
322372 | fah
Type: gene
Organism: zebrafish
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Gene
712716 | FAH
Type: gene
Organism: macaque, rhesus
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Gene
100135385 | fah
Type: gene
Organism: frog, western clawed
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Gene
29383 | Fah
Type: gene
Organism: rat
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Protein Coding Gene
MGI:95482 | Fah
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
31611405 | J:282284
First Author: Yang S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Tissue-specific FAH deficiency alters sleep-wake patterns and results in chronic tyrosinemia in mice.
Volume: 116
Issue: 44
Pages: 22229-22236
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Publication
29527263 | J:284926
First Author: Junge N
Year: 2018
Journal: World J Hepatol
Title: Homologous recombination mediates stable Fah gene integration and phenotypic correction in tyrosinaemia mouse-model.
Volume: 10
Issue: 2
Pages: 277-286
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Publication
28006671 | J:262087
 
First Author: Winer BY
Year: 2017
Journal: Virology
Title: Recapitulation of treatment response patterns in a novel humanized mouse model for chronic hepatitis B virus infection.
Volume: 502
Pages: 63-72
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Publication
9101289 | J:41529
First Author: St-Louis M
Year: 1997
Journal: Hum Mutat
Title: Mutations in the fumarylacetoacetate hydrolase gene causing hereditary tyrosinemia type I: overview.
Volume: 9
Issue: 4
Pages: 291-9
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Publication
2344618 | J:10522
First Author: Ruppert S
Year: 1990
Journal: Cell
Title: Two genetically defined trans-acting loci coordinately regulate overlapping sets of liver-specific genes.
Volume: 61
Issue: 5
Pages: 895-904
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Publication
24681508 | J:207452
First Author: Yin H
Year: 2014
Journal: Nat Biotechnol
Title: Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.
Volume: 32
Issue: 6
Pages: 551-3
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Publication
2697636 | J:30930
First Author: McKnight SL
Year: 1989
Journal: Genes Dev
Title: Is CCAAT/enhancer-binding protein a central regulator of energy metabolism?
Volume: 3
Issue: 12B
Pages: 2021-4
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Publication
1741389 | J:2947
First Author: Klebig ML
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Murine fumarylacetoacetate hydrolase (Fah) gene is disrupted by a neonatally lethal albino deletion that defines the hepatocyte-specific developmental regulation 1 (hsdr-1) locus.
Volume: 89
Issue: 4
Pages: 1363-7
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Publication
1520318 | J:2147
First Author: Collins JC
Year: 1992
Journal: Biochem Biophys Res Commun
Title: Metabolic studies in a mouse model of hepatorenal tyrosinemia: absence of perinatal abnormalities.
Volume: 187
Issue: 1
Pages: 340-6
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Publication
8253378 | J:16046
First Author: Grompe M
Year: 1993
Journal: Genes Dev
Title: Loss of fumarylacetoacetate hydrolase is responsible for the neonatal hepatic dysfunction phenotype of lethal albino mice.
Volume: 7
Issue: 12A
Pages: 2298-307
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Publication
7545495 | J:27735
First Author: Grompe M
Year: 1995
Journal: Nat Genet
Title: Pharmacological correction of neonatal lethal hepatic dysfunction in a murine model of hereditary tyrosinaemia type I.
Volume: 10
Issue: 4
Pages: 453-60
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Publication
31887661 | J:338671
First Author: Krooss SA
Year: 2020
Journal: iScience
Title: Ex Vivo/In vivo Gene Editing in Hepatocytes Using "All-in-One" CRISPR-Adeno-Associated Virus Vectors with a Self-Linearizing Repair Template.
Volume: 23
Issue: 1
Pages: 100764
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Publication
8589717 | J:31758
First Author: Overturf K
Year: 1996
Journal: Nat Genet
Title: Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I.
Volume: 12
Issue: 3
Pages: 266-73
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Publication
9095403 | J:40279
First Author: Overturf K
Year: 1997
Journal: Hum Gene Ther
Title: Adenovirus-mediated gene therapy in a mouse model of hereditary tyrosinemia type I.
Volume: 8
Issue: 5
Pages: 513-21
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Publication
18023223 | J:131342
First Author: Langlois C
Year: 2008
Journal: Mol Genet Metab
Title: Rescue from neonatal death in the murine model of hereditary tyrosinemia by glutathione monoethylester and vitamin C treatment.
Volume: 93
Issue: 3
Pages: 306-13
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Publication
18435462 | J:265383
First Author: Wangensteen KJ
Year: 2008
Journal: Hepatology
Title: A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver.
Volume: 47
Issue: 5
Pages: 1714-24
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Publication
26360553 | J:231399
First Author: Angileri F
Year: 2015
Journal: Biochim Biophys Acta
Title: Molecular changes associated with chronic liver damage and neoplastic lesions in a murine model of hereditary tyrosinemia type 1.
Volume: 1852
Issue: 12
Pages: 2603-17
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Publication
19229314 | J:146785
First Author: Duncan AW
Year: 2009
Journal: PLoS Genet
Title: Ploidy reductions in murine fusion-derived hepatocytes.
Volume: 5
Issue: 2
Pages: e1000385
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Publication
20162619 | J:207453
First Author: Paulk NK
Year: 2010
Journal: Hepatology
Title: Adeno-associated virus gene repair corrects a mouse model of hereditary tyrosinemia in vivo.
Volume: 51
Issue: 4
Pages: 1200-8
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Publication
1297646 | J:4991
 
First Author: Kelsey G
Year: 1992
Journal: J Cell Sci Suppl
Title: Multiple effects on liver-specific gene expression in albino lethal mice caused by deficiency of an enzyme in tyrosine metabolism.
Volume: 16
Pages: 117-22
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Publication
8253377 | J:16056
First Author: Kelsey G
Year: 1993
Journal: Genes Dev
Title: Rescue of mice homozygous for lethal albino deletions: implications for an animal model for the human liver disease tyrosinemia type 1.
Volume: 7
Issue: 12A
Pages: 2285-97
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Publication
17064256 | J:118549
First Author: Bateman RL
Year: 2007
Journal: Biochem J
Title: Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics.
Volume: 402
Issue: 2
Pages: 251-60
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Publication
10518553 | J:77295
First Author: Manning K
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: In vivo suppressor mutations correct a murine model of hereditary tyrosinemia type I.
Volume: 96
Issue: 21
Pages: 11928-33
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Publication
21374658 | J:308846
First Author: Keng VW
Year: 2011
Journal: Hepatology
Title: Modeling hepatitis B virus X-induced hepatocellular carcinoma in mice with the Sleeping Beauty transposon system.
Volume: 53
Issue: 3
Pages: 781-90
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Publication
7767008 | J:22809
First Author: Potter MD
Year: 1995
Journal: Mamm Genome
Title: Genetic and physical mapping of the fitness 1 (fit1) locus within the Fes-Hbb region of mouse chromosome 7.
Volume: 6
Issue: 2
Pages: 70-5
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Publication
22863619 | J:191301
First Author: Duncan AW
Year: 2012
Journal: J Clin Invest
Title: Aneuploidy as a mechanism for stress-induced liver adaptation.
Volume: 122
Issue: 9
Pages: 3307-15
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Publication
12899938 | J:119177
First Author: Dieter MZ
Year: 2003
Journal: Free Radic Biol Med
Title: Pharmacological rescue of the 14CoS/14CoS mouse: hepatocyte apoptosis is likely caused by endogenous oxidative stress.
Volume: 35
Issue: 4
Pages: 351-67
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Publication
1644288 | J:1836
First Author: Ruppert S
Year: 1992
Journal: Genes Dev
Title: Deficiency of an enzyme of tyrosine metabolism underlies altered gene expression in newborn liver of lethal albino mice.
Volume: 6
Issue: 8
Pages: 1430-43
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Publication
9305902 | J:43207
First Author: Endo F
Year: 1997
Journal: J Biol Chem
Title: Complete rescue of lethal albino c14CoS mice by null mutation of 4-hydroxyphenylpyruvate dioxygenase and induction of apoptosis of hepatocytes in these mice by in vivo retrieval of the tyrosine catabolic pathway.
Volume: 272
Issue: 39
Pages: 24426-32
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Publication
21917493 | J:178220
First Author: Hamman KJ
Year: 2011
Journal: Mol Genet Metab
Title: Hepatocytes from wild-type or heterozygous donors are equally effective in achieving successful therapeutic liver repopulation in murine phenylketonuria (PKU).
Volume: 104
Issue: 3
Pages: 235-40
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Publication
29348399 | J:288213
First Author: Wang MJ
Year: 2018
Journal: Cell Death Dis
Title: Insulin-like growth factor 2 is a key mitogen driving liver repopulation in mice.
Volume: 9
Issue: 2
Pages: 26
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Publication
11209059 | J:67045
First Author: Aponte JL
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Point mutations in the murine fumarylacetoacetate hydrolase gene: Animal models for the human genetic disorder hereditary tyrosinemia type 1.
Volume: 98
Issue: 2
Pages: 641-5
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Publication
35259493 | J:324041
First Author: Wang H
Year: 2022
Journal: Cell Mol Gastroenterol Hepatol
Title: Coordinated Cross-Talk Between the Myc and Mlx Networks in Liver Regeneration and Neoplasia.
Volume: 13
Issue: 6
Pages: 1785-1804
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Publication
10665936 | J:60506
First Author: Sun MS
Year: 2000
Journal: J Am Soc Nephrol
Title: A mouse model of renal tubular injury of tyrosinemia type 1: development of de Toni Fanconi syndrome and apoptosis of renal tubular cells in Fah/Hpd double mutant mice.
Volume: 11
Issue: 2
Pages: 291-300
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Publication
9168903 | J:40515
First Author: Vasiliou V
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Extrahepatic expression of NAD(P)H:menadione oxidoreductase, UDP glucuronosyltransferase-1A6, microsomal aldehyde dehydrogenase, and hepatic nuclear factor-1 alpha mRNAs in ch/ch and 14CoS/14CoS mice.
Volume: 233
Issue: 3
Pages: 631-6
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Publication
25575590 | J:278569
First Author: Pircher H
Year: 2015
Journal: J Biol Chem
Title: Identification of FAH domain-containing protein 1 (FAHD1) as oxaloacetate decarboxylase.
Volume: 290
Issue: 11
Pages: 6755-62
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Protein Coding Gene
MGP_CAROLIEiJ_G0029948 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032459 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032436 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032373 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032449 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032163 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_95482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032940 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031489 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032128 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032283 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032237 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032364 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032274 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032960 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031210 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031606 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013169 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031052 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1524868 | J:2852
First Author: Grompe M
Year: 1992
Journal: Biochem Med Metab Biol
Title: Nucleotide sequence of a cDNA encoding murine fumarylacetoacetate hydrolase.
Volume: 48
Issue: 1
Pages: 26-31
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Publication
38490194 | J:346584
First Author: Zwirner S
Year: 2024
Journal: Cell
Title: First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure.
Volume: 187
Issue: 7
Pages: 1666-1684.e26
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Publication
28993411 | J:252310
First Author: Tschida BR
Year: 2017
Journal: Cancer Res
Title: Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors.
Volume: 77
Issue: 23
Pages: 6576-6588
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Publication
28961327 | J:298030
First Author: Riordan JD
Year: 2018
Journal: Hepatology
Title: Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma in mice.
Volume: 67
Issue: 3
Pages: 924-939
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Publication
29760381 | J:311527
First Author: Wang C
Year: 2018
Journal: Cell Death Dis
Title: The extent of liver injury determines hepatocyte fate toward senescence or cancer.
Volume: 9
Issue: 5
Pages: 575
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Publication
22996664 | J:191751
First Author: Vaughan AM
Year: 2012
Journal: J Clin Invest
Title: Complete Plasmodium falciparum liver-stage development in liver-chimeric mice.
Volume: 122
Issue: 10
Pages: 3618-28
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Publication
16317004 | J:109228
First Author: Bergeron A
Year: 2006
Journal: J Biol Chem
Title: Involvement of endoplasmic reticulum stress in hereditary tyrosinemia type I.
Volume: 281
Issue: 9
Pages: 5329-34
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Publication
25191899 | J:221527
First Author: Qi Z
Year: 2014
Journal: PLoS One
Title: Bone marrow transplantation concurrently reconstitutes donor liver and immune system across host species barrier in mice.
Volume: 9
Issue: 9
Pages: e106791
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Publication
34557483 | J:311452
 
First Author: Lu F
Year: 2021
Journal: Front Cell Dev Biol
Title: A Three-Dimensional Imaging Method for the Quantification and Localization of Dynamic Cell Tracking Posttransplantation.
Volume: 9
Pages: 698795
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Publication
11825062 | J:74405
First Author: Al-Dhalimy M
Year: 2002
Journal: Mol Genet Metab
Title: Long-term therapy with NTBC and tyrosine-restricted diet in a murine model of hereditary tyrosinemia type I.
Volume: 75
Issue: 1
Pages: 38-45
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Publication
16581029 | J:111141
First Author: Langlois C
Year: 2006
Journal: Biochem Pharmacol
Title: Evaluation of dichloroacetate treatment in a murine model of hereditary tyrosinemia type 1.
Volume: 71
Issue: 11
Pages: 1648-61
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Publication
14767996 | J:105440
First Author: Vogel A
Year: 2004
Journal: Hepatology
Title: Chronic liver disease in murine hereditary tyrosinemia type 1 induces resistance to cell death.
Volume: 39
Issue: 2
Pages: 433-43
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Publication
22209984 | J:182711
First Author: van Dyk E
Year: 2012
Journal: Gene
Title: Impaired DNA repair and genomic stability in hereditary tyrosinemia type 1.
Volume: 495
Issue: 1
Pages: 56-61
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Publication
20861837 | J:232920
First Author: Duncan AW
Year: 2010
Journal: Nature
Title: The ploidy conveyor of mature hepatocytes as a source of genetic variation.
Volume: 467
Issue: 7316
Pages: 707-10
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Publication
21632826 | J:194657
First Author: Dorrell C
Year: 2011
Journal: Genes Dev
Title: Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice.
Volume: 25
Issue: 11
Pages: 1193-203
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Publication
11062533 | J:65494
First Author: Lagasse E
Year: 2000
Journal: Nat Med
Title: Purified hematopoietic stem cells can differentiate into hepatocytes in vivo.
Volume: 6
Issue: 11
Pages: 1229-34
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Publication
29091290 | J:255667
     
First Author: Wangensteen KJ
Year: 2017
Journal: Hepatology
Title: Combinatorial genetics in liver repopulation and carcinogenesis with a novel in vivo CRISPR activation platform.
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Publication
35361222 | J:326591
First Author: Kopasz AG
Year: 2022
Journal: BMC Biol
Title: A versatile transposon-based technology to generate loss- and gain-of-function phenotypes in the mouse liver.
Volume: 20
Issue: 1
Pages: 74
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Publication
37025950 | J:339460
 
First Author: Imre G
Year: 2023
Journal: Mol Ther Methods Clin Dev
Title: Prolonged activity of the transposase helper may raise safety concerns during DNA transposon-based gene therapy.
Volume: 29
Pages: 145-159
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Publication
31740768 | J:285822
First Author: Song CQ
Year: 2020
Journal: Nat Biomed Eng
Title: Adenine base editing in an adult mouse model of tyrosinaemia.
Volume: 4
Issue: 1
Pages: 125-130
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Publication
29787760 | J:272481
First Author: Shin JH
Year: 2018
Journal: Biochem Biophys Res Commun
Title: In vivo gene correction with targeted sequence substitution through microhomology-mediated end joining.
Volume: 502
Issue: 1
Pages: 116-122
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Publication
32332735 | J:292332
First Author: Jiang T
Year: 2020
Journal: Nat Commun
Title: Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope.
Volume: 11
Issue: 1
Pages: 1979
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Publication
30976745 | J:285267
First Author: VanLith CJ
Year: 2019
Journal: Hepatol Commun
Title: Ex Vivo Hepatocyte Reprograming Promotes Homology-Directed DNA Repair to Correct Metabolic Disease in Mice After Transplantation.
Volume: 3
Issue: 4
Pages: 558-573
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Publication
23444141 | J:231263
First Author: Moriarity BS
Year: 2013
Journal: Nucleic Acids Res
Title: Modular assembly of transposon integratable multigene vectors using RecWay assembly.
Volume: 41
Issue: 8
Pages: e92
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GXD Expression
GXD Expression
     
Probe: MGI:5292483
Assay Type: RT-PCR
Annotation Date: 2011-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:5292384
Age: embryonic day 14.5
Specimen Label: e14.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5292483
Assay Type: RT-PCR
Annotation Date: 2011-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:5292384
Age: embryonic day 14.5
Specimen Label: e14.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5292483
Assay Type: RT-PCR
Annotation Date: 2011-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:5292384
Age: embryonic day 16.5
Specimen Label: e16.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5292483
Assay Type: RT-PCR
Annotation Date: 2011-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:5292384
Age: embryonic day 16.5
Specimen Label: e16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5292483
Assay Type: RT-PCR
Annotation Date: 2011-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684626
Stage: TS26
Assay Id: MGI:5292384
Age: embryonic day 18.5
Specimen Label: e18.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5292483
Assay Type: RT-PCR
Annotation Date: 2011-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684626
Stage: TS26
Assay Id: MGI:5292384
Age: embryonic day 18.5
Specimen Label: e18.5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:5309914
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3516422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423240
Age: embryonic day 14.5
Image: EB1227; Specimen B505
Specimen Label: EB1227; Specimen B505
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309914
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716122
Stage: TS22
Assay Id: MGI:5423240
Age: embryonic day 14.5
Specimen Label: EB1227; Specimen B505
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5309914
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423240
Age: embryonic day 14.5
Image: EB1227; Specimen B505
Specimen Label: EB1227; Specimen B505
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309914
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1760622
Stage: TS22
Assay Id: MGI:5423240
Age: embryonic day 14.5
Specimen Label: EB1227; Specimen B505
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309914
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737322
Stage: TS22
Assay Id: MGI:5423240
Age: embryonic day 14.5
Specimen Label: EB1227; Specimen B505
Detected: false
Specimen Num: 1
•
•
•
•
•




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