| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tian Y |
| Year: |
2015 |
| Journal: |
Eur J Oral Sci |
| Title: |
Inactivation of Fam20B in the dental epithelium of mice leads to supernumerary incisors. |
| Volume: |
123 |
| Issue: |
6 |
| Pages: |
396-402 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu X |
| Year: |
2018 |
| Journal: |
Eur J Oral Sci |
| Title: |
Inactivation of Fam20b in the neural crest-derived mesenchyme of mouse causes multiple craniofacial defects. |
| Volume: |
126 |
| Issue: |
5 |
| Pages: |
433-436 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ma P |
| Year: |
2016 |
| Journal: |
Sci Rep |
| Title: |
Inactivation of Fam20B in Joint Cartilage Leads to Chondrosarcoma and Postnatal Ossification Defects. |
| Volume: |
6 |
|
| Pages: |
29814 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Saiyin W |
| Year: |
2019 |
| Journal: |
Biochim Biophys Acta Mol Basis Dis |
| Title: |
Inactivation of FAM20B causes cell fate changes in annulus fibrosus of mouse intervertebral disc and disc defects via the alterations of TGF-β and MAPK signaling pathways. |
| Volume: |
1865 |
| Issue: |
12 |
| Pages: |
165555 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nalbant D |
| Year: |
2005 |
| Journal: |
BMC Genomics |
| Title: |
FAM20: an evolutionarily conserved family of secreted proteins expressed in hematopoietic cells. |
| Volume: |
6 |
|
| Pages: |
11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vogel P |
| Year: |
2012 |
| Journal: |
Vet Pathol |
| Title: |
Amelogenesis imperfecta and other biomineralization defects in Fam20a and Fam20c null mice. |
| Volume: |
49 |
| Issue: |
6 |
| Pages: |
998-1017 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen X |
| Year: |
2023 |
| Journal: |
Int J Mol Sci |
| Title: |
Deficiency of Fam20b-Catalyzed Glycosaminoglycan Chain Synthesis in Neural Crest Leads to Cleft Palate. |
| Volume: |
24 |
| Issue: |
11 |
|
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4887998 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-02-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3514928 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:4888029 |
| Age: |
postnatal |
|
|
| Specimen Label: |
Wt |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4887998 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-02-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3514928 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:4888029 |
| Age: |
postnatal |
|
|
| Specimen Label: |
+/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4887998 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-02-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3514928 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:4888029 |
| Age: |
postnatal |
|
|
| Specimen Label: |
-/- |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6404763 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2020-04-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1790622 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:6404891 |
| Age: |
embryonic day 14.5 |
| Image: |
1 |
|
| Specimen Label: |
Diastema |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6404763 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2020-04-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1791822 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:6404891 |
| Age: |
embryonic day 14.5 |
| Image: |
1 |
|
| Specimen Label: |
Incisor |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6404763 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2020-04-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1792122 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:6404891 |
| Age: |
embryonic day 14.5 |
| Image: |
1 |
|
| Specimen Label: |
Molar |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
O'Sullivan J |
| Year: |
2011 |
| Journal: |
Am J Hum Genet |
| Title: |
Whole-Exome sequencing identifies FAM20A mutations as a cause of amelogenesis imperfecta and gingival hyperplasia syndrome. |
| Volume: |
88 |
| Issue: |
5 |
| Pages: |
616-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ishikawa HO |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
The Raine syndrome protein FAM20C is a Golgi kinase that phosphorylates bio-mineralization proteins. |
| Volume: |
7 |
| Issue: |
8 |
| Pages: |
e42988 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Watanabe Y |
| Year: |
2010 |
| Journal: |
Biochem J |
| Title: |
Chondroitin sulfate N-acetylgalactosaminyltransferase-1 is required for normal cartilage development. |
| Volume: |
432 |
| Issue: |
1 |
| Pages: |
47-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu J |
| Year: |
2020 |
| Journal: |
BMC Biol |
| Title: |
FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling. |
| Volume: |
18 |
| Issue: |
1 |
| Pages: |
87 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rios JJ |
| Year: |
2021 |
| Journal: |
J Bone Miner Res |
| Title: |
Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice. |
| Volume: |
36 |
| Issue: |
8 |
| Pages: |
1548-1565 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu J |
| Year: |
2020 |
| Journal: |
Gene Expr Patterns |
| Title: |
The spatiotemporal expression pattern of Syndecans in murine embryonic teeth. |
| Volume: |
36 |
|
| Pages: |
119109 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brommage R |
| Year: |
2014 |
| Journal: |
Bone Res |
| Title: |
High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes. |
| Volume: |
2 |
|
| Pages: |
14034 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Naba A |
| Year: |
2017 |
| Journal: |
Sci Rep |
| Title: |
Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. |
| Volume: |
7 |
|
| Pages: |
40495 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Abonnenc M |
| Year: |
2013 |
| Journal: |
Circ Res |
| Title: |
Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. |
| Volume: |
113 |
| Issue: |
10 |
| Pages: |
1138-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
MGC Data curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Friedel RH |
| Year: |
2007 |
| Journal: |
Brief Funct Genomic Proteomic |
| Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
| Volume: |
6 |
| Issue: |
3 |
| Pages: |
180-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wellcome Trust Sanger Institute |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zambrowicz BP |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
100 |
| Issue: |
24 |
| Pages: |
14109-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Skarnes WC |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
| Volume: |
474 |
| Issue: |
7351 |
| Pages: |
337-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
|
| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Koike T |
| Year: |
2009 |
| Journal: |
Biochem J |
| Title: |
FAM20B is a kinase that phosphorylates xylose in the glycosaminoglycan-protein linkage region. |
| Volume: |
421 |
| Issue: |
2 |
| Pages: |
157-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hao J |
| Year: |
2007 |
| Journal: |
J Biol Chem |
| Title: |
Dentin matrix protein 4, a novel secretory calcium-binding protein that modulates odontoblast differentiation. |
| Volume: |
282 |
| Issue: |
21 |
| Pages: |
15357-65 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
203
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Simpson MA |
| Year: |
2007 |
| Journal: |
Am J Hum Genet |
| Title: |
Mutations in FAM20C are associated with lethal osteosclerotic bone dysplasia (Raine syndrome), highlighting a crucial molecule in bone development. |
| Volume: |
81 |
| Issue: |
5 |
| Pages: |
906-12 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
FAM20 is a family of secreted proteins with a potential role in regulating differentiation and function of hematopoietic and other tissues. Proteins in this family include FAM20A [], FAM20B or glycosaminoglycan xylosylkinase [], and FAM20C or dentin matrix protein 4 [, ]. |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
579
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
541
 |
| Fragment?: |
false |
|
•
•
•
•
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|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
409
 |
| Fragment?: |
false |
|
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•
•
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