|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 221 for Fam3c

<< First    < Previous  |  Next >    Last >>
0.06s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein Domain
Type: Family
Description: Protein FAM3C, also known as interleukin-like EMT inducer (ILEI), participates in the formation of TGF-beta1-induced renal tubular epithelial-to-mesenchymal transition (EMT) and has been linked to EMT in some diseases []. It is a hepatokine that suppresses hepatic gluconeogenic gene expression and insulin-independent gluconeogenesis by activating the HSF1-CaM-Akt pathway. It activates transcriptor heat shock factor 1 (HSF1) to induce CALM1 gene expression and increase calmodulin (CaM) protein level. An increase in CaM protein level suppresses glucose production by inducing Akt activation [, ].
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Chen Z
Year: 2017
Journal: Diabetes
Title: Hepatic Activation of the FAM3C-HSF1-CaM Pathway Attenuates Hyperglycemia of Obese Diabetic Mice.
Volume: 66
Issue: 5
Pages: 1185-1197
Protein
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 99  
Fragment?: false
Gene
Type: gene
Organism: human
Protein
Organism: Mus musculus/domesticus
Length: 303  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 227  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 197  
Fragment?: false
Publication  
First Author: Pilipenko VV
Year: 2004
Journal: Gene
Title: Genomic organization and expression analysis of the murine Fam3c gene.
Volume: 335
Pages: 159-68
Publication
First Author: Chen Z
Year: 2017
Journal: Oncotarget
Title: FAM3C activates HSF1 to suppress hepatic gluconeogenesis and attenuate hyperglycemia of type 1 diabetic mice.
Volume: 8
Issue: 62
Pages: 106038-106049
Publication
First Author: Zhao X
Year: 2018
Journal: Cell Biochem Funct
Title: ILEI is an important intermediate participating in the formation of TGF-β1-induced renal tubular EMT.
Volume: 36
Issue: 2
Pages: 46-55
Publication
First Author: Katahira T
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Secreted factor FAM3C (ILEI) is involved in retinal laminar formation.
Volume: 392
Issue: 3
Pages: 301-6
Publication
First Author: Zhu Y
Year: 2002
Journal: Genomics
Title: Cloning, expression, and initial characterization of a novel cytokine-like gene family.
Volume: 80
Issue: 2
Pages: 144-50
Publication  
First Author: Määttä JA
Year: 2016
Journal: Bonekey Rep
Title: Fam3c modulates osteogenic cell differentiation and affects bone volume and cortical bone mineral density.
Volume: 5
Pages: 787
UniProt Feature
Begin: 25
Description: Protein FAM3C
Type: chain
End: 227
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Malik B
Year: 2023
Journal: EMBO Mol Med
Title: FAM3C/ILEI protein is elevated in psoriatic lesions and triggers psoriasiform hyperproliferation in mice.
Volume: 15
Issue: 7
Pages: e16758
Publication
First Author: Schmidt U
Year: 2023
Journal: PLoS One
Title: Inducible overexpression of a FAM3C/ILEI transgene has pleiotropic effects with shortened life span, liver fibrosis and anemia in mice.
Volume: 18
Issue: 9
Pages: e0286256
GXD Expression      
Probe: MGI:1331890
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:1331891
Age: embryonic day 7.5
Specimen Label: 1x
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1331890
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:1331891
Age: embryonic day 7.5
Specimen Label: 10x
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1331890
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:1331891
Age: embryonic day 7.5
Specimen Label: 100x
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:1331890
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:1331891
Age: embryonic day 7.5
Specimen Label: 1x
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1331890
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:1331891
Age: embryonic day 7.5
Specimen Label: 10x
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:1331890
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:1331891
Age: embryonic day 7.5
Specimen Label: 100x
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:7435571
Assay Type: RT-PCR
Annotation Date: 2023-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7435603
Age: postnatal month 2
Specimen Label: Wild-type
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7435571
Assay Type: RT-PCR
Annotation Date: 2023-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7435603
Age: postnatal month 2
Specimen Label: Nrl<-/->
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7494065
Age: postnatal
Specimen Label: Mouse brain
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7494066
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7494066
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7494066
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271528
Stage: TS28
Assay Id: MGI:7494066
Age: postnatal adult
Specimen Label: Muscle
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:7494066
Age: postnatal adult
Specimen Label: Pancreas
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7494066
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:7494066
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7494066
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:7494066
Age: postnatal adult
Specimen Label: Thymus
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:7494066
Age: postnatal adult
Specimen Label: Intestine
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:7494066
Age: postnatal adult
Specimen Label: Colon
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7494067
Age: postnatal adult
Specimen Label: Cerebral cortex
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:7494067
Age: postnatal adult
Specimen Label: Striatum
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Stage: TS28
Assay Id: MGI:7494067
Age: postnatal adult
Specimen Label: Thalamus
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:7494067
Age: postnatal adult
Specimen Label: Cerebellum
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7494067
Age: postnatal adult
Specimen Label: Hippocampus
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Stage: TS28
Assay Id: MGI:7494067
Age: postnatal adult
Specimen Label: Brainstem
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Stage: TS28
Assay Id: MGI:7494067
Age: postnatal adult
Specimen Label: Hypothalamus
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283728
Stage: TS28
Assay Id: MGI:7494067
Age: postnatal adult
Specimen Label: Septum
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7494078
Age: postnatal adult
Specimen Label: H
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:7494081
Age: embryonic day 17.5
Specimen Label: E17.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7494081
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7494081
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7494081
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7494081
Age: postnatal day 14
Specimen Label: P14
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7494081
Age: postnatal day 21
Specimen Label: P21
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7494081
Age: postnatal month 6
Specimen Label: 6m
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7494081
Age: postnatal month 13
Specimen Label: 13m
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:7494082
Age: embryonic day 17.5
Specimen Label: E17.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7494082
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7494082
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7494082
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7494082
Age: postnatal day 14
Specimen Label: P14
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7494082
Age: postnatal day 21
Specimen Label: P21
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7494082
Age: postnatal month 6
Specimen Label: 6m
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7494056
Assay Type: Western blot
Annotation Date: 2023-06-29
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7494082
Age: postnatal month 13
Specimen Label: 13m
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:7494056
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-29
Strength: Weak
Sex: Male
Emaps: EMAPS:3569828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7494068
Age: postnatal adult
Specimen Label: not shown
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:7494056
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-29
Strength: Moderate
Sex: Male
Emaps: EMAPS:3592328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7494068
Age: postnatal adult
Specimen Label: not shown
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:7494056
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-29
Strength: Present
Sex: Male
Emaps: EMAPS:1689528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7494068
Age: postnatal adult
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7494056
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-29
Strength: Present
Sex: Male
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7494068
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7494056
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-29
Strength: Very strong
Sex: Male
Emaps: EMAPS:3519628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7494068
Age: postnatal adult
Specimen Label: 2F
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7494056
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-29
Strength: Weak
Sex: Male
Emaps: EMAPS:3554328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7494068
Age: postnatal adult
Specimen Label: not shown
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:7494056
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-29
Strength: Weak
Sex: Male
Emaps: EMAPS:1909528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7494068
Age: postnatal adult
Specimen Label: not shown
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:7494056
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-29
Strength: Present
Sex: Male
Emaps: EMAPS:3660828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7494073
Age: postnatal adult
Specimen Label: 5B
Detected: true
Specimen Num: 5