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Search results 1 to 100 out of 178 for Fanca

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0.036s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: Fanconi anemia (FA) is a human disorder characterized by cancer susceptibility and cellular sensitivity to DNA crosslinks and other damages. The FA complex repairs the interstrand cross-linking (ICL) lesions and coordinates activities of the downstream DNA repair pathway including nucleotide excision repair, translesion synthesis, and homologous recombination. It is required for the monoubiquitylation of FANCD2 and FANCI heterodimer. The FA core complex consists of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL, FANCM, FANCT (UBET2), FAAP100 and FAAP24 [, ].This entry represents FANCA [].
Publication
First Author: Du W
Year: 2014
Journal: Blood
Title: Deletion of Fanca or Fancd2 dysregulates Treg in mice.
Volume: 123
Issue: 12
Pages: 1938-47
Publication
First Author: Abdul-Sater Z
Year: 2015
Journal: Exp Hematol
Title: FANCA safeguards interphase and mitosis during hematopoiesis in vivo.
Volume: 43
Issue: 12
Pages: 1031-1046.e12
Publication
First Author: Nguyen TV
Year: 2014
Journal: J Exp Med
Title: Fanca deficiency reduces A/T transitions in somatic hypermutation and alters class switch recombination junctions in mouse B cells.
Volume: 211
Issue: 6
Pages: 1011-8
Publication
First Author: van de Vrugt HJ
Year: 2000
Journal: Mamm Genome
Title: Cloning and characterization of murine fanconi anemia group A gene: Fanca protein is expressed in lymphoid tissues, testis, and ovary.
Volume: 11
Issue: 4
Pages: 326-31
Protein
Organism: Mus musculus
Length: 169  
Fragment?: true
Protein
Organism: Mus musculus
Length: 1439  
Fragment?: false
Protein
Organism: Mus musculus
Length: 771  
Fragment?: true
Protein
Organism: Mus musculus
Length: 481  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1439  
Fragment?: false
Publication
First Author: Yan Z
Year: 2010
Journal: Mol Cell
Title: A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability.
Volume: 37
Issue: 6
Pages: 865-78
Publication
First Author: Bhattacharjee S
Year: 2017
Journal: Cell Commun Signal
Title: DNA damage response and cancer therapeutics through the lens of the Fanconi Anemia DNA repair pathway.
Volume: 15
Issue: 1
Pages: 41
DO Term
Publication
First Author: Pawlikowska P
Year: 2014
Journal: Blood
Title: Defective endomitosis during megakaryopoiesis leads to thrombocytopenia in Fanca-/- mice.
Volume: 124
Issue: 24
Pages: 3613-23
Publication
First Author: Yang YG
Year: 2005
Journal: Carcinogenesis
Title: The Fanconi anemia group A protein modulates homologous repair of DNA double-strand breaks in mammalian cells.
Volume: 26
Issue: 10
Pages: 1731-40
Publication
First Author: Abu-Issa R
Year: 1999
Journal: Blood
Title: Expression of the Fanconi anemia group A gene (Fanca) during mouse embryogenesis.
Volume: 94
Issue: 2
Pages: 818-24
Publication
First Author: Wong JC
Year: 2000
Journal: Genomics
Title: Cloning and analysis of the mouse Fanconi anemia group A cDNA and an overlapping penta zinc finger cDNA.
Volume: 67
Issue: 3
Pages: 273-83
Publication
First Author: Du W
Year: 2013
Journal: J Immunol
Title: Inflammation-mediated notch signaling skews fanconi anemia hematopoietic stem cell differentiation.
Volume: 191
Issue: 5
Pages: 2806-17
Publication
First Author: Sii-Felice K
Year: 2008
Journal: EMBO J
Title: Fanconi DNA repair pathway is required for survival and long-term maintenance of neural progenitors.
Volume: 27
Issue: 5
Pages: 770-81
Publication
First Author: Du W
Year: 2017
Journal: Leukemia
Title: The immune receptor Trem1 cooperates with diminished DNA damage response to induce preleukemic stem cell expansion.
Volume: 31
Issue: 2
Pages: 423-433
Publication
First Author: Noll M
Year: 2002
Journal: Exp Hematol
Title: Fanconi anemia group A and C double-mutant mice: functional evidence for a multi-protein Fanconi anemia complex.
Volume: 30
Issue: 7
Pages: 679-88
Publication
First Author: Zhang T
Year: 2015
Journal: Stem Cells
Title: Loss of Faap20 Causes Hematopoietic Stem and Progenitor Cell Depletion in Mice Under Genotoxic Stress.
Volume: 33
Issue: 7
Pages: 2320-30
Publication
First Author: Xu J
Year: 2018
Journal: Stem Cells
Title: Reduced Cell Division Control Protein 42 Activity Compromises Hematopoiesis-Supportive Function of Fanconi Anemia Mesenchymal Stromal Cells.
Volume: 36
Issue: 5
Pages: 785-795
Publication
First Author: Wong JC
Year: 2003
Journal: Hum Mol Genet
Title: Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia.
Volume: 12
Issue: 16
Pages: 2063-76
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Cheng NC
Year: 2000
Journal: Hum Mol Genet
Title: Mice with a targeted disruption of the Fanconi anemia homolog Fanca.
Volume: 9
Issue: 12
Pages: 1805-11
Publication
First Author: Nakanishi K
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair.
Volume: 102
Issue: 4
Pages: 1110-5
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2002-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2179485
Age: postnatal adult
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2016-10-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5805212
Age: postnatal week 10
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2016-10-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5805212
Age: postnatal week 10
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2002-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2179485
Age: postnatal adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2179500
Assay Type: RT-PCR
Annotation Date: 2002-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2179529
Age: postnatal adult
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5475277
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3291019
Stage: TS19
Assay Id: MGI:5475291
Age: embryonic day 11.5
Image: 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5475277
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Female
Emaps: EMAPS:2890922
Stage: TS22
Assay Id: MGI:5475291
Age: embryonic day 14.5
Image: 1
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2002-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2179485
Age: postnatal adult
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2179500
Assay Type: RT-PCR
Annotation Date: 2002-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2179529
Age: postnatal adult
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2002-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2179485
Age: postnatal adult
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2002-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2179496
Age: embryonic day 17.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2002-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2179496
Age: embryonic day 15.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2002-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2179496
Age: embryonic day 11.0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2002-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2179496
Age: embryonic day 7.0
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5804677
Assay Type: RT-PCR
Annotation Date: 2016-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:5805234
Age: embryonic day 8.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5804677
Assay Type: RT-PCR
Annotation Date: 2016-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:5805234
Age: embryonic day 10.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5475277
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674419
Stage: TS19
Assay Id: MGI:5475291
Age: embryonic day 11.5
Image: 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5475277
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Male
Emaps: EMAPS:1674424
Stage: TS24
Assay Id: MGI:5475291
Age: embryonic day 16.5
Image: 1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5475277
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Female
Emaps: EMAPS:1674424
Stage: TS24
Assay Id: MGI:5475291
Age: embryonic day 16.5
Image: 1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5475277
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Male
Emaps: EMAPS:2913822
Stage: TS22
Assay Id: MGI:5475291
Age: embryonic day 14.5
Image: 1
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2002-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2179485
Age: postnatal adult
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5475277
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797222
Stage: TS22
Assay Id: MGI:5475291
Age: embryonic day 14.5
Image: 1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5475277
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:5475291
Age: embryonic day 16.5
Image: 1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5804677
Assay Type: RT-PCR
Annotation Date: 2016-10-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5805209
Age: postnatal week 10
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5804677
Assay Type: RT-PCR
Annotation Date: 2016-10-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5805209
Age: postnatal week 10
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:5804677
Assay Type: RT-PCR
Annotation Date: 2016-10-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5805209
Age: postnatal week 10
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5804678
Assay Type: RT-PCR
Annotation Date: 2016-10-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5805211
Age: postnatal week 10
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5804678
Assay Type: RT-PCR
Annotation Date: 2016-10-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5805211
Age: postnatal week 10
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5804678
Assay Type: RT-PCR
Annotation Date: 2016-10-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5805211
Age: postnatal week 10
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2016-10-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5805212
Age: postnatal week 10
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2016-10-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5805212
Age: postnatal week 10
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2002-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:2179485
Age: postnatal adult
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2179500
Assay Type: RT-PCR
Annotation Date: 2002-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:2179529
Age: postnatal adult
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2002-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:2179485
Age: postnatal adult
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2179500
Assay Type: RT-PCR
Annotation Date: 2002-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:2179529
Age: postnatal adult
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5475277
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:5475291
Age: embryonic day 11.5
Image: 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2002-05-28
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:2179485
Age: postnatal adult
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:2179483
Assay Type: Northern blot
Annotation Date: 2002-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2179485
Age: postnatal adult
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2179500
Assay Type: RT-PCR
Annotation Date: 2002-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2179529
Age: postnatal adult
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5475277
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Female
Emaps: EMAPS:1796222
Stage: TS22
Assay Id: MGI:5475291
Age: embryonic day 14.5
Image: 1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5475277
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Female
Emaps: EMAPS:1796224
Stage: TS24
Assay Id: MGI:5475291
Age: embryonic day 16.5
Image: 1
Detected: true
Specimen Num: 5
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-10-25
Strength: Absent
Sex: Male
Emaps: EMAPS:3148428
Stage: TS28
Assay Id: MGI:5805219
Age: postnatal week 10
Note: No expression in stage VI spermatocytes.
Detected: false
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-10-25
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5805219
Age: postnatal week 10
Note: Expresse in stage VIII spermatocytes.
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-10-25
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5805219
Age: postnatal week 10
Note: Expressed in stage X spermatocytes.
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2179483
Assay Type: RNA in situ
Annotation Date: 2016-10-25
Strength: Strong
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5805242
Age: postnatal week 10
Detected: true
Specimen Num: 1
GXD Expression        
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-10-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:5805219
Age: embryonic day 7.5
Detected: false
Specimen Num: 6
GXD Expression        
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-10-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:5805219
Age: embryonic day 7.5
Detected: false
Specimen Num: 7
GXD Expression        
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-10-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5805219
Age: embryonic day 13.5
Detected: false
Specimen Num: 8
GXD Expression        
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-10-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5805219
Age: embryonic day 13.5
Detected: false
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-10-25
Strength: Present
Sex: Male
Emaps: EMAPS:3147628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5805219
Age: postnatal week 10
Note: Expressed in segments in a periodic pattern.
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-10-25
Strength: Present
Sex: Male
Emaps: EMAPS:3147628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5805219
Age: postnatal week 10
Note: Expressed in segments in a periodic pattern.
Detected: true
Specimen Num: 2