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Search results 1 to 80 out of 80 for Fancb

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
2187 | FANCB
Type: gene
Organism: human
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Gene
100497907 | fancb
Type: gene
Organism: frog, western clawed
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Gene
108179053 | fancb
Type: gene
Organism: zebrafish
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Gene
501552 | Fancb
Type: gene
Organism: rat
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Gene
737001 | FANCB
Type: gene
Organism: chimpanzee
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Gene
616549 | FANCB
Type: gene
Organism: cattle
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Gene
100687493 | FANCB
Type: gene
Organism: dog, domestic
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Gene
418628 | FANCB
Type: gene
Organism: chicken
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Gene
712083 | FANCB
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2448558 | Fancb
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR033333 | FANCB
Type: Family
Description: FANCB (also known as FAAP95) is a component of the Fanconi anemia (FA) core complex []. The FA core complex mediates FANCD2 ubiquitination, a key activation step in the FA DNA damage response pathway [, , ]. The FANCB and the FA pathway also play a critical role in germ cell development []and in the maintenance of hematopoietic stem cell function [].FA is a recessive genetic disorder characterised by congenital abnormalities, progressive bone marrow failure and cancer susceptibility []. Eight proteins (FANCA, B, C, E, F, G, L and M) encoded by the FA causative genes have been demonstrated to form the FA nuclear core complex.
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Publication
26658157 | J:244681
 
First Author: Du W
Year: 2015
Journal: Sci Rep
Title: Fancb deficiency impairs hematopoietic stem cell function.
Volume: 5
Pages: 18127
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Publication
26123487 | J:224588
First Author: Kato Y
Year: 2015
Journal: Hum Mol Genet
Title: FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis.
Volume: 24
Issue: 18
Pages: 5234-49
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Protein
Q497Q5
Organism: Mus musculus/domesticus
Length: 236  
Fragment?: true
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Publication
35596251 | J:333943
First Author: Cen C
Year: 2022
Journal: Biol Reprod
Title: Fancb deficiency causes premature ovarian insufficiency in mice†.
Volume: 107
Issue: 3
Pages: 790-799
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Publication
15611632 | -
First Author: Fei P
Year: 2005
Journal: Cell Cycle
Title: New advances in the DNA damage response network of Fanconi anemia and BRCA proteins. FAAP95 replaces BRCA2 as the true FANCB protein.
Volume: 4
Issue: 1
Pages: 80-6
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Protein
Q5XJY6
Organism: Mus musculus/domesticus
Length: 703  
Fragment?: false
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Protein
Q3TEX6
Organism: Mus musculus/domesticus
Length: 853  
Fragment?: false
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Protein
B1AW75
Organism: Mus musculus/domesticus
Length: 706  
Fragment?: false
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Publication
16720839 | -
First Author: Medhurst AL
Year: 2006
Journal: Blood
Title: Evidence for subcomplexes in the Fanconi anemia pathway.
Volume: 108
Issue: 6
Pages: 2072-80
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Publication
24910428 | -
First Author: Huang Y
Year: 2014
Journal: Cell Rep
Title: Modularized functions of the Fanconi anemia core complex.
Volume: 7
Issue: 6
Pages: 1849-57
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Publication
19264559 | -
First Author: Alpi AF
Year: 2009
Journal: DNA Repair (Amst)
Title: Monoubiquitylation in the Fanconi anemia DNA damage response pathway.
Volume: 8
Issue: 4
Pages: 430-5
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Publication
16357213 | -
First Author: Kennedy RD
Year: 2005
Journal: Genes Dev
Title: The Fanconi Anemia/BRCA pathway: new faces in the crowd.
Volume: 19
Issue: 24
Pages: 2925-40
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Protein Coding Gene
MGP_CAROLIEiJ_G0033566 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0036260 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0036230 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0036158 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0036223 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035930 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2448558 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0036746 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0035218 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035904 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0036070 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0036002 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0036155 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0036034 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0036785 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034916 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0035353 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0032106 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0034737 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:3219489
Assay Type: RNA in situ
Annotation Date: 2024-05-29
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7643322
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3219489
Assay Type: RNA in situ
Annotation Date: 2024-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7643322
Age: embryonic day 14.5
Note: Ventricular zone expression was greater than in the cortical plate.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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Publication
25520194 | J:223244
First Author: Kim TM
Year: 2015
Journal: Nucleic Acids Res
Title: RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway.
Volume: 43
Issue: 2
Pages: 893-903
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Publication
27760317 | J:240753
First Author: Alavattam KG
Year: 2016
Journal: Cell Rep
Title: Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.
Volume: 17
Issue: 4
Pages: 1141-1157
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Publication
12477932 | J:82808
First Author: Strausberg RL
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Volume: 99
Issue: 26
Pages: 16899-903
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q8K3C9
Organism: Mus musculus/domesticus
Length: 63  
Fragment?: false
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DO Term
DOID:0111098 | Fanconi anemia complementation group B
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DO Term
DOID:0111766 | X-linked VACTERL association
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Gene
7547 | ZIC3
Type: gene
Organism: human
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Publication
27986371 | J:253010
First Author: van Twest S
Year: 2017
Journal: Mol Cell
Title: Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway.
Volume: 65
Issue: 2
Pages: 247-259
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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