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Search results 1 to 100 out of 103 for Fancg

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Hits by Pathway

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Type Details Score
Gene
2189 | FANCG
Type: gene
Organism: human
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Gene
465067 | FANCG
Type: gene
Organism: chimpanzee
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Gene
615352 | FANCG
Type: gene
Organism: cattle
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Gene
378893 | FANCG
Type: gene
Organism: chicken
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Gene
402936 | fancg
Type: gene
Organism: zebrafish
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Gene
698837 | FANCG
Type: gene
Organism: macaque, rhesus
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Gene
100145235 | fancg
Type: gene
Organism: frog, western clawed
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Gene
691105 | Fancg
Type: gene
Organism: rat
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Gene
611887 | FANCG
Type: gene
Organism: dog, domestic
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Protein Domain
IPR039684 | FANCG
Type: Family
Description: Fanconi anemia (FA) is a human disorder characterized by cancer susceptibility and cellular sensitivity to DNA crosslinks and other damages. This entry represents FANCG, which is part of the FA core complex required for the monoubiquitylation of FANCD2 and the FANCI heterodimer. The FA complex coordinates activities of the downstream DNA repair pathway including nucleotide excision repair, translesion synthesis, and homologous recombination []. Besides being part of the FA complex, FANCG also promotes formation of a protein complex containing BRCA2, FANCD2 and XRCC3 [].
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Protein Coding Gene
MGI:1926471 | Fancg
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q80X51
Organism: Mus musculus/domesticus
Length: 258  
Fragment?: false
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Protein
A4QPC9
Organism: Mus musculus/domesticus
Length: 616  
Fragment?: false
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Publication
18212739 | -
First Author: Wilson JB
Year: 2008
Journal: Oncogene
Title: FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3.
Volume: 27
Issue: 26
Pages: 3641-52
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Publication
20606166 | J:165874
First Author: Pulliam-Leath AC
Year: 2010
Journal: Blood
Title: Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.
Volume: 116
Issue: 16
Pages: 2915-20
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Protein
Q9EQR6
Organism: Mus musculus/domesticus
Length: 623  
Fragment?: false
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Protein
B9EJ17
Organism: Mus musculus/domesticus
Length: 623  
Fragment?: false
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Publication
29017571 | -
First Author: Bhattacharjee S
Year: 2017
Journal: Cell Commun Signal
Title: DNA damage response and cancer therapeutics through the lens of the Fanconi Anemia DNA repair pathway.
Volume: 15
Issue: 1
Pages: 41
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Publication
21968513 | J:178857
First Author: Barroca V
Year: 2012
Journal: Hum Mol Genet
Title: Impaired functionality and homing of Fancg-deficient hematopoietic stem cells.
Volume: 21
Issue: 1
Pages: 121-35
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Publication
15319283 | J:95292
First Author: Franco S
Year: 2004
Journal: Blood
Title: Telomere dynamics in Fancg-deficient mouse and human cells.
Volume: 104
Issue: 13
Pages: 3927-35
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Publication
11719385 | J:72945
First Author: Yang Y
Year: 2001
Journal: Blood
Title: Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9.
Volume: 98
Issue: 12
Pages: 3435-40
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Publication
19129541 | J:146189
First Author: Li Y
Year: 2009
Journal: Blood
Title: Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg-/- mice in vivo.
Volume: 113
Issue: 10
Pages: 2342-51
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Publication
37446306 | J:338032
 
First Author: Shah R
Year: 2023
Journal: Int J Mol Sci
Title: A C57BL/6J Fancg-KO Mouse Model Generated by CRISPR/Cas9 Partially Captures the Human Phenotype.
Volume: 24
Issue: 13
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Publication
11823446 | J:74737
First Author: Koomen M
Year: 2002
Journal: Hum Mol Genet
Title: Reduced fertility and hypersensitivity to mitomycin C characterize Fancg/Xrcc9 null mice.
Volume: 11
Issue: 3
Pages: 273-81
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Publication
28341737 | J:285820
First Author: Zhou Y
Year: 2017
Journal: Haematologica
Title: An abnormal bone marrow microenvironment contributes to hematopoietic dysfunction in Fanconi anemia.
Volume: 102
Issue: 6
Pages: 1017-1027
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Publication
21118969 | J:167132
First Author: Reliene R
Year: 2010
Journal: Cancer Res
Title: Genomic instability in mice is greater in Fanconi anemia caused by deficiency of Fancd2 than Fancg.
Volume: 70
Issue: 23
Pages: 9703-10
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Publication
16946306 | J:140439
First Author: Si Y
Year: 2006
Journal: Blood
Title: Continuous in vivo infusion of interferon-gamma (IFN-gamma) enhances engraftment of syngeneic wild-type cells in Fanca-/- and Fancg-/- mice.
Volume: 108
Issue: 13
Pages: 4283-7
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Publication
22036606 | J:330492
First Author: van de Vrugt HJ
Year: 2011
Journal: DNA Repair (Amst)
Title: Evidence for complete epistasis of null mutations in murine Fanconi anemia genes Fanca and Fancg.
Volume: 10
Issue: 12
Pages: 1252-61
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Protein Coding Gene
MGP_CAROLIEiJ_G0025926 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028197 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028153 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028105 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028173 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027895 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1926471 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028614 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027335 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027861 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0028010 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027977 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028109 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0028001 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028650 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027061 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027415 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024071 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026887 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:5475279
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3291019
Stage: TS19
Assay Id: MGI:5475294
Age: embryonic day 11.5
Image: 1
Specimen Label: E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5475279
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674419
Stage: TS19
Assay Id: MGI:5475294
Age: embryonic day 11.5
Image: 1
Specimen Label: E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5475279
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:5475294
Age: embryonic day 11.5
Image: 1
Specimen Label: E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5475279
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Male
Emaps: EMAPS:2913822
Stage: TS22
Assay Id: MGI:5475294
Age: embryonic day 14.5
Image: 1
Specimen Label: E14.5 Male
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5475279
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797222
Stage: TS22
Assay Id: MGI:5475294
Age: embryonic day 14.5
Image: 1
Specimen Label: E14.5 Male
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5475279
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Male
Emaps: EMAPS:1674424
Stage: TS24
Assay Id: MGI:5475294
Age: embryonic day 16.5
Image: 1
Specimen Label: E16.5 Male
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5475279
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:5475294
Age: embryonic day 16.5
Image: 1
Specimen Label: E16.5 Male
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5475279
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Female
Emaps: EMAPS:2890922
Stage: TS22
Assay Id: MGI:5475294
Age: embryonic day 14.5
Image: 1
Specimen Label: E14.5 Female
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5475279
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Present
Sex: Female
Emaps: EMAPS:1796222
Stage: TS22
Assay Id: MGI:5475294
Age: embryonic day 14.5
Image: 1
Specimen Label: E14.5 Female
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5475279
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Absent
Sex: Female
Emaps: EMAPS:1674424
Stage: TS24
Assay Id: MGI:5475294
Age: embryonic day 16.5
Image: 1
Specimen Label: E16.5 Female
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5475279
Assay Type: RT-PCR
Annotation Date: 2013-04-25
Strength: Absent
Sex: Female
Emaps: EMAPS:1796224
Stage: TS24
Assay Id: MGI:5475294
Age: embryonic day 16.5
Image: 1
Specimen Label: E16.5 Female
Detected: false
Specimen Num: 5
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Publication
- | J:70955
   
First Author: Tipping AJ
Year: 2001
Journal: GenBank Submission
Title: Mus musculus Fanconi anemia group G protein mRNA, complete cds
Pages: AF112439
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Publication
24799500 | J:213121
First Author: Nguyen TV
Year: 2014
Journal: J Exp Med
Title: Fanca deficiency reduces A/T transitions in somatic hypermutation and alters class switch recombination junctions in mouse B cells.
Volume: 211
Issue: 6
Pages: 1011-8
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Publication
17431503 | J:122036
First Author: Kennedy RD
Year: 2007
Journal: J Clin Invest
Title: Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated.
Volume: 117
Issue: 5
Pages: 1440-9
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Publication
20921626 | J:166938
First Author: Vinciguerra P
Year: 2010
Journal: J Clin Invest
Title: Cytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cells.
Volume: 120
Issue: 11
Pages: 3834-42
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Publication
12135664 | J:77903
First Author: Noll M
Year: 2002
Journal: Exp Hematol
Title: Fanconi anemia group A and C double-mutant mice: functional evidence for a multi-protein Fanconi anemia complex.
Volume: 30
Issue: 7
Pages: 679-88
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Publication
12627171 | J:163809
First Author: Yang Y
Year: 2003
Journal: Nat Biotechnol
Title: Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes.
Volume: 21
Issue: 4
Pages: 447-51
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Publication
10951504 | J:64334
First Author: Nadler JJ
Year: 2000
Journal: Genesis
Title: Fanconi anemia complementation group C is required for proliferation of murine primordial germ cells.
Volume: 27
Issue: 3
Pages: 117-23
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Publication
23806336 | J:199241
First Author: Park E
Year: 2013
Journal: Mol Cell
Title: FANCD2 activates transcription of TAp63 and suppresses tumorigenesis.
Volume: 50
Issue: 6
Pages: 908-18
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Publication
18239686 | J:131848
First Author: Sii-Felice K
Year: 2008
Journal: EMBO J
Title: Fanconi DNA repair pathway is required for survival and long-term maintenance of neural progenitors.
Volume: 27
Issue: 5
Pages: 770-81
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Publication
12360237 | J:79958
First Author: Cooke HJ
Year: 2002
Journal: Nat Rev Genet
Title: Mouse models of male infertility.
Volume: 3
Issue: 10
Pages: 790-801
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Publication
15970507 | J:103183
 
First Author: Naz RK
Year: 2005
Journal: Front Biosci
Title: Gene knockouts that cause female infertility: search for novel contraceptive targets.
Volume: 10
Pages: 2447-59
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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