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Search results 1 to 100 out of 494 for Fap

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Ramirez-Montagut T
Year: 2004
Journal: Oncogene
Title: FAPalpha, a surface peptidase expressed during wound healing, is a tumor suppressor.
Volume: 23
Issue: 32
Pages: 5435-46
Publication
First Author: Niedermeyer J
Year: 1998
Journal: Eur J Biochem
Title: Mouse fibroblast-activation protein--conserved Fap gene organization and biochemical function as a serine protease.
Volume: 254
Issue: 3
Pages: 650-4
Publication
First Author: Zhao W
Year: 1999
Journal: J Biol Chem
Title: Characterization of the fibronectin binding motif for a unique mycobacterial fibronectin attachment protein, FAP.
Volume: 274
Issue: 8
Pages: 4521-6
Publication
First Author: Yang X
Year: 2016
Journal: Cancer Res
Title: FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling.
Volume: 76
Issue: 14
Pages: 4124-35
Publication
First Author: Niedermeyer J
Year: 1997
Journal: Int J Cancer
Title: Mouse fibroblast activation protein: molecular cloning, alternative splicing and expression in the reactive stroma of epithelial cancers.
Volume: 71
Issue: 3
Pages: 383-9
Publication
First Author: Niedermeyer J
Year: 2001
Journal: Int J Dev Biol
Title: Expression of the fibroblast activation protein during mouse embryo development.
Volume: 45
Issue: 2
Pages: 445-7
Publication
First Author: Niedermeyer J
Year: 2000
Journal: Mol Cell Biol
Title: Targeted disruption of mouse fibroblast activation protein.
Volume: 20
Issue: 3
Pages: 1089-94
Protein
Organism: Mus musculus/domesticus
Length: 63  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 761  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 47  
Fragment?: true
Publication
First Author: Dunshee DR
Year: 2016
Journal: J Biol Chem
Title: Fibroblast Activation Protein Cleaves and Inactivates Fibroblast Growth Factor 21.
Volume: 291
Issue: 11
Pages: 5986-96
Publication  
First Author: Blomberg R
Year: 2019
Journal: Matrix Biol
Title: Fibroblast activation protein restrains adipogenic differentiation and regulates matrix-mediated mTOR signaling.
Volume: 83
Pages: 60-76
Protein
Organism: Mus musculus/domesticus
Length: 736  
Fragment?: false
Publication
First Author: Tan SY
Year: 2017
Journal: PLoS One
Title: Fibroblast activation protein is dispensable in the anti-influenza immune response in mice.
Volume: 12
Issue: 2
Pages: e0171194
Publication
First Author: Gunderson AJ
Year: 2019
Journal: PLoS One
Title: Blockade of fibroblast activation protein in combination with radiation treatment in murine models of pancreatic adenocarcinoma.
Volume: 14
Issue: 2
Pages: e0211117
Publication
First Author: Hoffmann DB
Year: 2021
Journal: PLoS One
Title: Genetic ablation of fibroblast activation protein alpha attenuates left ventricular dilation after myocardial infarction.
Volume: 16
Issue: 3
Pages: e0248196
Publication
First Author: Kimura T
Year: 2019
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Loss of cells expressing fibroblast activation protein has variable effects in models of TGF-β and chronic bleomycin-induced fibrosis.
Volume: 317
Issue: 2
Pages: L271-L282
Publication
First Author: Fan MH
Year: 2016
Journal: J Biol Chem
Title: Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice.
Volume: 291
Issue: 15
Pages: 8070-89
Publication
First Author: Bainbridge TW
Year: 2017
Journal: Sci Rep
Title: Selective Homogeneous Assay for Circulating Endopeptidase Fibroblast Activation Protein (FAP).
Volume: 7
Issue: 1
Pages: 12524
Publication
First Author: Stein S
Year: 2021
Journal: Cardiovasc Res
Title: Deletion of fibroblast activation protein provides atheroprotection.
Volume: 117
Issue: 4
Pages: 1060-1069
Publication
First Author: Wei H
Year: 2020
Journal: Cell Rep
Title: Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target.
Volume: 33
Issue: 2
Pages: 108252
Protein
Organism: Mus musculus/domesticus
Length: 728  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 756  
Fragment?: false
Publication
First Author: Santos AM
Year: 2009
Journal: J Clin Invest
Title: Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice.
Volume: 119
Issue: 12
Pages: 3613-25
Publication
First Author: Muliaditan T
Year: 2018
Journal: Nat Commun
Title: Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis.
Volume: 9
Issue: 1
Pages: 2951
Publication
First Author: Monslow J
Year: 2020
Journal: Am J Pathol
Title: Fibroblast Activation Protein Regulates Lesion Burden and the Fibroinflammatory Response in Apoe-Deficient Mice in a Sexually Dimorphic Manner.
Volume: 190
Issue: 5
Pages: 1118-1136
UniProt Feature
Begin: 11
Description: FAP motif
Type: short sequence motif
End: 13
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication  
First Author: Li X
Year: 2021
Journal: Cancer Lett
Title: Targeting FAPα-expressing tumor-associated mesenchymal stromal cells inhibits triple-negative breast cancer pulmonary metastasis.
Volume: 503
Pages: 32-42
Publication
First Author: Roberts EW
Year: 2013
Journal: J Exp Med
Title: Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia.
Volume: 210
Issue: 6
Pages: 1137-51
Publication
First Author: Denton AE
Year: 2019
Journal: J Exp Med
Title: Embryonic FAP+ lymphoid tissue organizer cells generate the reticular network of adult lymph nodes.
Volume: 216
Issue: 10
Pages: 2242-2252
GXD Expression        
Probe: MGI:2662725
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2662738
Age: embryonic day 7.0
Specimen Label: None
Specimen Num: 1
GXD Expression        
Probe: MGI:2662725
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2662738
Age: embryonic day 11.0
Specimen Label: None
Specimen Num: 2
GXD Expression      
Probe: MGI:2662725
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:2662738
Age: embryonic day 14.0
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2662725
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2662738
Age: embryonic day 17.0
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression        
Probe: MGI:2662725
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:2662738
Age: embryonic day 19.0
Specimen Label: None
Specimen Num: 5
GXD Expression        
Probe: MGI:2662725
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:2576527
Stage: TS27
Assay Id: MGI:2662738
Age: postnatal day 1
Specimen Label: None
Specimen Num: 6
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2662770
Age: embryonic day 7.0
Specimen Label: None
Specimen Num: 1
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2662770
Age: embryonic day 11.0
Specimen Label: None
Specimen Num: 2
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2662770
Age: embryonic day 11.0
Specimen Label: None
Specimen Num: 3
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2662770
Age: embryonic day 11.0
Specimen Label: None
Specimen Num: 5
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:2662770
Age: embryonic day 14.0
Specimen Label: None
Specimen Num: 6
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3185822
Stage: TS22
Assay Id: MGI:2662770
Age: embryonic day 14.0
Specimen Label: None
Specimen Num: 7
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3185722
Stage: TS22
Assay Id: MGI:2662770
Age: embryonic day 14.0
Specimen Label: None
Specimen Num: 8
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2662770
Age: embryonic day 14.0
Specimen Label: None
Specimen Num: 9
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3185825
Stage: TS25
Assay Id: MGI:2662770
Age: embryonic day 17.0
Specimen Label: None
Specimen Num: 11
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3185725
Stage: TS25
Assay Id: MGI:2662770
Age: embryonic day 17.0
Specimen Label: None
Specimen Num: 12
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2662770
Age: embryonic day 17.0
Specimen Label: None
Specimen Num: 13
GXD Expression      
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2662776
Age: embryonic day 7.0
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2662776
Age: embryonic day 11.0
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2662776
Age: embryonic day 11.0
Specimen Label: None
Specimen Num: 3
GXD Expression      
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2662776
Age: embryonic day 11.0
Specimen Label: None
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:2662776
Age: embryonic day 14.0
Specimen Label: None
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185822
Stage: TS22
Assay Id: MGI:2662776
Age: embryonic day 14.0
Specimen Label: None
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185722
Stage: TS22
Assay Id: MGI:2662776
Age: embryonic day 14.0
Specimen Label: None
Detected: true
Specimen Num: 8
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2662776
Age: embryonic day 14.0
Specimen Label: None
Specimen Num: 9
GXD Expression      
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185825
Stage: TS25
Assay Id: MGI:2662776
Age: embryonic day 17.0
Specimen Label: None
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185725
Stage: TS25
Assay Id: MGI:2662776
Age: embryonic day 17.0
Specimen Label: None
Detected: true
Specimen Num: 12
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2662776
Age: embryonic day 17.0
Specimen Label: None
Specimen Num: 13
GXD Expression        
Probe: MGI:2662725
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:2662822
Age: postnatal adult
Specimen Label: Colon
Specimen Num: 1
GXD Expression        
Probe: MGI:2662725
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2662822
Age: postnatal adult
Specimen Label: Kidney
Specimen Num: 2
GXD Expression        
Probe: MGI:2662725
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2662822
Age: postnatal adult
Specimen Label: Liver
Specimen Num: 3
GXD Expression        
Probe: MGI:2662725
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2662822
Age: postnatal adult
Specimen Label: Lung
Specimen Num: 4
GXD Expression        
Probe: MGI:2662725
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:2662822
Age: postnatal adult
Specimen Label: Ovary
Specimen Num: 5
GXD Expression        
Probe: MGI:2662725
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:2662822
Age: postnatal adult
Specimen Label: Pancreas
Specimen Num: 6
GXD Expression        
Probe: MGI:2662725
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:2662822
Age: postnatal adult
Specimen Label: Skin
Specimen Num: 7
GXD Expression      
Probe: MGI:2662725
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:2662822
Age: embryonic day 14.0
Specimen Label: E14
Detected: true
Specimen Num: 14
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:2662770
Age: postnatal
Specimen Label: None
Specimen Num: 4
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:2662770
Age: postnatal
Specimen Label: None
Specimen Num: 10
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:2662770
Age: postnatal
Specimen Label: None
Specimen Num: 14
GXD Expression        
Probe: MGI:2662728
Assay Type: RT-PCR
Annotation Date: 2003-06-16
Strength: Not Specified
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:2662776
Age: postnatal
Specimen Label: None
Specimen Num: 4