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Search results 1 to 100 out of 102 for Far1

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
84188 | FAR1
Type: gene
Organism: human
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Gene
100038270 | far1
Type: gene
Organism: frog, western clawed
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Gene
293173 | Far1
Type: gene
Organism: rat
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Gene
476863 | FAR1
Type: gene
Organism: dog, domestic
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Gene
451036 | FAR1
Type: gene
Organism: chimpanzee
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Gene
525262 | FAR1
Type: gene
Organism: cattle
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Gene
423028 | FAR1
Type: gene
Organism: chicken
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Gene
406829 | far1
Type: gene
Organism: zebrafish
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Gene
699947 | FAR1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1914670 | Far1
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
106478978 | FAR1-IT1
Type: gene
Organism: human
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Publication
37039784 | J:339470
First Author: Pan B
Year: 2023
Journal: FASEB J
Title: Disrupted intercellular bridges and spermatogenesis in fatty acyl-CoA reductase 1 knockout mice: A new model of ether lipid deficiency.
Volume: 37
Issue: 5
Pages: e22908
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Publication
15220348 | J:92394
First Author: Cheng JB
Year: 2004
Journal: J Biol Chem
Title: Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions.
Volume: 279
Issue: 36
Pages: 37789-97
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Protein Coding Gene
MGP_CAROLIEiJ_G0030342 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032876 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032859 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032791 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032864 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032574 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1914670 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033370 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031902 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032547 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032699 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032652 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032793 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032684 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033390 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031609 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032015 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013554 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031457 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
15220349 | J:92651
First Author: Cheng JB
Year: 2004
Journal: J Biol Chem
Title: Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family.
Volume: 279
Issue: 36
Pages: 37798-807
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Publication
20562862 | J:161922
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
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Publication
- | J:171883
     
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
18715961 | -
First Author: Lin R
Year: 2008
Journal: Plant Physiol
Title: Discrete and essential roles of the multiple domains of Arabidopsis FHY3 in mediating phytochrome A signal transduction.
Volume: 148
Issue: 2
Pages: 981-92
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Protein Domain
IPR004330 | FAR1_DNA_bnd_dom
Type: Domain
Description: Phytochrome A is the primary photoreceptor for mediating various far-red light-induced responses in higher plants. It has been found that the proteins governing this response, which include FAR-RED ELONGATED HYPOCOTYL3 (FHY3) and FAR-RED-IMPAIRED RESPONSE1 (FAR1), are a pair of homologous proteins sharing significant sequence homology to mutator-like transposases. These proteins appear to be novel transcription factors, which are essential for activating the expression of FHY1 and FHL (for FHY1-like) and related genes, whose products are required for light-induced phytochrome A nuclear accumulation and subsequent light responses in plants.The FRS (FAR1 Related Sequences) family of proteins share a similar domain structure to mutator-like transposases, including an N-terminal C2H2 zinc finger domain, a central putative core transposase domain, and a C-terminal SWIM motif (named after SWI2/SNF and MuDR transposases). It seems plausible that the FRS family represent transcription factors derived from mutator-like transposases [, ]. This entry represents a domain found in FAR1 and FRS proteins. It contains a WRKY like fold and is therefore most likely a zinc binding DNA-binding domain.
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Publication
15591448 | -
First Author: Lin R
Year: 2004
Journal: Plant Physiol
Title: Arabidopsis FHY3/FAR1 gene family and distinct roles of its members in light control of Arabidopsis development.
Volume: 136
Issue: 4
Pages: 4010-22
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Allele
Far1<em1(IMPC)Wtsi> | MGI:6153339
Name: fatty acyl CoA reductase 1; endonuclease-mediated mutation 1, Wellcome Trust Sanger Institute
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
11080155 | -
First Author: Blondel M
Year: 2000
Journal: EMBO J
Title: Nuclear-specific degradation of Far1 is controlled by the localization of the F-box protein Cdc4.
Volume: 19
Issue: 22
Pages: 6085-97
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DO Term
DOID:0081243 | rhizomelic chondrodysplasia punctate type 4
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Publication
22634759 | -
First Author: Tang W
Year: 2012
Journal: Plant Cell
Title: Transposase-derived proteins FHY3/FAR1 interact with PHYTOCHROME-INTERACTING FACTOR1 to regulate chlorophyll biosynthesis by modulating HEMB1 during deetiolation in Arabidopsis.
Volume: 24
Issue: 5
Pages: 1984-2000
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Publication
23946351 | -
First Author: Tang W
Year: 2013
Journal: Plant Physiol
Title: FAR-RED ELONGATED HYPOCOTYL3 and FAR-RED IMPAIRED RESPONSE1 transcription factors integrate light and abscisic acid signaling in Arabidopsis.
Volume: 163
Issue: 2
Pages: 857-66
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Protein Domain
IPR040018 | XPO5
Type: Family
Description: Exportin-5 mediates the nuclear export of proteins bearing a double-stranded RNA binding domain (dsRBD) and double-stranded RNAs (cargos) []. Exportin-5 yeast homologue, also known as Msn5, is involved in nuclear import of replication protein A and export of Far1 and transcription factors Swi5, Swi6, Msn2, and Pho4 [, , ]. Its Arabidopsis homologue, HASTY 1, is involved in the nuclear export of microRNAs (miRNAs) [].
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Protein Domain
IPR031052 | FHY3/FAR1
Type: Family
Description: This entry represents a group of plant and fungal proteins, including a number of Arbidopsis FHY3/FAR1-related proteins []. FHY3 (FAR-RED ELONGATED HYPOCOTYL3) and FAR1 (FAR-RED IMPAIRED RESPONSE1) are transcription factors derived from ancient transposases during evolution. They are involved in chlorophyll biosynthesis via the activation of HEMB1 gene expression []. They can also integrate light and abscisic acid signaling in Arabidopsis []and may have broad functions in plant growth and development [].
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Publication
22555597 | -
First Author: Verheggen C
Year: 2012
Journal: Nucleus
Title: CRM1 plays a nuclear role in transporting snoRNPs to nucleoli in higher eukaryotes.
Volume: 3
Issue: 2
Pages: 132-7
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Publication
15574332 | -
First Author: Boulon S
Year: 2004
Journal: Mol Cell
Title: PHAX and CRM1 are required sequentially to transport U3 snoRNA to nucleoli.
Volume: 16
Issue: 5
Pages: 777-87
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Protein Domain
IPR045065 | XPO1/5
Type: Family
Description: This entry includes exportin-1/5 from eukaryotes.Exportin-1, also known as CRM1, is a nuclear export receptor that have been shown to be involved in U3 snoRNA transport from Cajal bodies to nucleoli []. It also controls the composition of many nucleoplasmic complexes [].Exportin-5 mediates the nuclear export of proteins bearing a double-stranded RNA binding domain (dsRBD) and double-stranded RNAs (cargos) []. Exportin-5 yeast homologue, also known as Msn5, is involved in nuclear import of replication protein A and export of Far1 and transcription factors Swi5, Swi6, Msn2, and Pho4 [, , ]. Its Arabidopsis homologue, HASTY 1, is involved in the nuclear export of microRNAs (miRNAs) [].
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Publication
11777942 | -
First Author: Brownawell AM
Year: 2002
Journal: J Cell Biol
Title: Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins.
Volume: 156
Issue: 1
Pages: 53-64
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Publication
12697814 | -
First Author: Queralt E
Year: 2003
Journal: Mol Cell Biol
Title: Cell cycle activation of the Swi6p transcription factor is linked to nucleocytoplasmic shuttling.
Volume: 23
Issue: 9
Pages: 3126-40
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Publication
22374135 | -
First Author: Taberner FJ
Year: 2012
Journal: Biochim Biophys Acta
Title: Regulation of cell cycle transcription factor Swi5 by karyopherin Msn5.
Volume: 1823
Issue: 4
Pages: 959-70
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Publication
35238077 | J:329410
First Author: Otsuka K
Year: 2022
Journal: FASEB J
Title: Formation of fatty alcohols-components of meibum lipids-by the fatty acyl-CoA reductase FAR2 is essential for dry eye prevention.
Volume: 36
Issue: 4
Pages: e22216
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Publication
22582101 | -
First Author: Chen F
Year: 2012
Journal: Plant Cell
Title: Phosphorylation of FAR-RED ELONGATED HYPOCOTYL1 is a key mechanism defining signaling dynamics of phytochrome A under red and far-red light in Arabidopsis.
Volume: 24
Issue: 5
Pages: 1907-20
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Publication
25071219 | -
First Author: Chen F
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Photoreceptor partner FHY1 has an independent role in gene modulation and plant development under far-red light.
Volume: 111
Issue: 32
Pages: 11888-93
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Publication
18670649 | -
First Author: Genoud T
Year: 2008
Journal: PLoS Genet
Title: FHY1 mediates nuclear import of the light-activated phytochrome A photoreceptor.
Volume: 4
Issue: 8
Pages: e1000143
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Publication
21969386 | -
First Author: Sokolova V
Year: 2012
Journal: Plant Physiol
Title: Missense mutation in the amino terminus of phytochrome A disrupts the nuclear import of the photoreceptor.
Volume: 158
Issue: 1
Pages: 107-18
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Publication
22374392 | -
First Author: Kami C
Year: 2012
Journal: Plant Cell
Title: Nuclear phytochrome A signaling promotes phototropism in Arabidopsis.
Volume: 24
Issue: 2
Pages: 566-76
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Publication
17566111 | -
First Author: Rösler J
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Arabidopsis fhl/fhy1 double mutant reveals a distinct cytoplasmic action of phytochrome A.
Volume: 104
Issue: 25
Pages: 10737-42
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Protein Domain
IPR037766 | FHY1
Type: Family
Description: This entry represents a group of plant proteins, including FHY1 (At2g37678) from Arabidopsis. Phytochrome A (phyA) is the photoreceptor in Arabidopsis that mediates the far-red light high radiance response. AtFHY1 is a key regulator of far red/red (FR/R) spectrum-specific responses by regulating phyA shuttling from the cytoplasm to the nucleus and by directly regulating the expression of some target genes. AtFHY1 phosphorylation is induced by the R signal, is part of the FR/R spectrum sensing mechanism that ensures its optimal response to specific light quality []. AtFHY1 also has an independent role in gene modulation and plant development under far-red light [].This entry also includes FHL (FHY1 Like). FHL is essential for light-regulated PHYA nuclear accumulation and subsequent PHYA phototropic signaling processes [, , ]. The transcription of FHY1 and FHL are controlled by FHY3 (Far-red elongated HYpocotyl 3) and FAR1 (FAr-red impaired Response 1), a related pair of transcription factors [].
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Publication
11266464 | -
First Author: Yoshida K
Year: 2001
Journal: J Cell Biol
Title: The karyopherin Kap142p/Msn5p mediates nuclear import and nuclear export of different cargo proteins.
Volume: 152
Issue: 4
Pages: 729-40
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Publication
15738428 | -
First Author: Park MY
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Nuclear processing and export of microRNAs in Arabidopsis.
Volume: 102
Issue: 10
Pages: 3691-6
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Publication
29557170 | J:292571
First Author: Kimura T
Year: 2018
Journal: Biochemistry
Title: Substantial Decrease in Plasmalogen in the Heart Associated with Tafazzin Deficiency.
Volume: 57
Issue: 14
Pages: 2162-2175
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Protein
Q9CZR7
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: false
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Protein
Q8BPF7
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: false
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Protein
A2AKT6
Organism: Mus musculus/domesticus
Length: 59  
Fragment?: true
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Protein
Q924C1
Organism: Mus musculus/domesticus
Length: 1204  
Fragment?: false
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Protein
A2RRJ4
Organism: Mus musculus/domesticus
Length: 1204  
Fragment?: false
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Protein
Q921J0
Organism: Mus musculus/domesticus
Length: 564  
Fragment?: false
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Protein
Q8BYY5
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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Cambridge CB2 3EH, United Kingdom