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Search results 1 to 100 out of 103 for Farp2

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0.062s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Toyofuku T
Year: 2005
Journal: Nat Neurosci
Title: FARP2 triggers signals for Sema3A-mediated axonal repulsion.
Volume: 8
Issue: 12
Pages: 1712-9
Publication
First Author: Su Z
Year: 2009
Journal: Arterioscler Thromb Vasc Biol
Title: Farp2 and Stk25 are candidate genes for the HDL cholesterol locus on mouse chromosome 1.
Volume: 29
Issue: 1
Pages: 107-13
Publication
First Author: He X
Year: 2013
Journal: Structure
Title: Structural basis for autoinhibition of the guanine nucleotide exchange factor FARP2.
Volume: 21
Issue: 3
Pages: 355-64
Publication
First Author: Kubo T
Year: 2002
Journal: J Neurosci
Title: A novel FERM domain including guanine nucleotide exchange factor is involved in Rac signaling and regulates neurite remodeling.
Volume: 22
Issue: 19
Pages: 8504-13
Publication
First Author: Takegahara N
Year: 2010
Journal: FASEB J
Title: Integral roles of a guanine nucleotide exchange factor, FARP2, in osteoclast podosome rearrangements.
Volume: 24
Issue: 12
Pages: 4782-92
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Kawakita A
Year: 2003
Journal: Brain Res Dev Brain Res
Title: Developmental regulation of FERM domain including guanine nucleotide exchange factor gene expression in the mouse brain.
Volume: 144
Issue: 2
Pages: 181-9
GXD Expression      
Probe: MGI:3028568
Assay Type: Northern blot
Annotation Date: 2004-02-22
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3028574
Age: postnatal adult
Image: 2
Specimen Num: 5
GXD Expression      
Probe: MGI:3028568
Assay Type: Northern blot
Annotation Date: 2004-02-22
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3028574
Age: postnatal adult
Image: 2
Specimen Num: 6
GXD Expression    
Probe: MGI:3028568
Assay Type: Northern blot
Annotation Date: 2004-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3028574
Age: embryonic day 13.0
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3028568
Assay Type: Northern blot
Annotation Date: 2004-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:3028574
Age: embryonic day 17.0
Image: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3028568
Assay Type: Northern blot
Annotation Date: 2004-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3028574
Age: postnatal day 7
Image: 2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3028568
Assay Type: Northern blot
Annotation Date: 2004-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3028574
Age: postnatal adult
Image: 2
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945630
Age: embryonic day 11.5
Image: g01165 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945630
Age: embryonic day 15.5
Image: g01165 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945630
Age: embryonic day 15.5
Image: g01165 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945630
Age: postnatal day 42
Image: g01165 Adult
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945630
Age: embryonic day 11.5
Image: g01165 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945630
Age: embryonic day 15.5
Image: g01165 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945630
Age: postnatal day 42
Image: g01165 Adult
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945630
Age: postnatal day 42
Image: g01165 Adult
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945630
Age: embryonic day 15.5
Image: g01165 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945630
Age: postnatal day 42
Image: g01165 Adult
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945630
Age: embryonic day 15.5
Image: g01165 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945630
Age: postnatal day 42
Image: g01165 Adult
Note: Expression was region specific and scattered.
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945630
Age: postnatal day 42
Image: g01165 Adult
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945630
Age: postnatal day 42
Image: g01165 Adult
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945630
Age: embryonic day 11.5
Image: g01165 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945630
Age: embryonic day 15.5
Image: g01165 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945630
Age: postnatal day 42
Image: g01165 Adult
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945630
Age: postnatal day 42
Image: g01165 Adult
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945630
Age: postnatal day 42
Image: g01165 Adult
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945630
Age: embryonic day 11.5
Image: g01165 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945630
Age: postnatal day 42
Image: g01165 Adult
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945630
Age: embryonic day 15.5
Image: g01165 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945630
Age: postnatal day 42
Image: g01165 Adult
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945630
Age: embryonic day 15.5
Image: g01165 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945630
Age: embryonic day 15.5
Image: g01165 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884376
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945630
Age: postnatal day 42
Image: g01165 Adult
Note: Expression was region specific and scattered.
Detected: true
Specimen Num: 3
Publication
First Author: Danelon V
Year: 2020
Journal: J Neurosci
Title: Modular and Distinct Plexin-A4/FARP2/Rac1 Signaling Controls Dendrite Morphogenesis.
Volume: 40
Issue: 28
Pages: 5413-5430
Publication
First Author: Coccia E
Year: 2020
Journal: Cell Death Dis
Title: SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L.
Volume: 11
Issue: 2
Pages: 82
Publication
First Author: Yoshizawa M
Year: 2003
Journal: Gene Expr Patterns
Title: Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain.
Volume: 3
Issue: 3
Pages: 375-81
Publication
First Author: DiTommaso T
Year: 2014
Journal: PLoS Genet
Title: Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse.
Volume: 10
Issue: 10
Pages: e1004705
Publication  
First Author: Liakath-Ali K
Year: 2014
Journal: Nat Commun
Title: Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.
Volume: 5
Pages: 3540
Publication      
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Kuo YC
Year: 2018
Journal: Sci Rep
Title: Structural analyses of FERM domain-mediated membrane localization of FARP1.
Volume: 8
Issue: 1
Pages: 10477
Publication  
First Author: Liu Z
Year: 2013
Journal: Mol Vis
Title: A novel missense mutation in the FERM domain containing 7 (FRMD7) gene causing X-linked idiopathic congenital nystagmus in a Chinese family.
Volume: 19
Pages: 1834-40
Protein Domain
Type: Domain
Description: The FERM domain has a cloverleaf tripart structure composed of: (1) FERM_N (A-lobe or F1); (2) FERM_M (B-lobe, or F2); and (3) FERM_C (C-lobe or F3). The C-lobe/F3 within the FERM domain is part of the PH domain family. Like most other ERM members they have a phosphoinositide-binding site in their FERM domain. The FERM C domain is the third structural domain within the FERM domain. The FERM domain is found in the cytoskeletal-associated proteins such as ezrin, moesin, radixin, 4.1R, and merlin. These proteins provide a link between the membrane and cytoskeleton and are involved in signal transduction pathways. The FERM domain is also found in protein tyrosine phosphatases (PTPs) , the tyrosine kinases FAK and JAK, in addition to other proteins involved in signaling. This domain is structurally similar to the PH and PTB domains and consequently is capable of binding to both peptides and phospholipids at different sites [, ].Proteins containing this domain include FARP1, FARP2 and FRMD7. FARP1 and FARP2 are members of the Dbl family guanine nucleotide exchange factors (GEFs) which are upstream positive regulators of Rho GTPases []. FARP1 has increased expression in differentiated chondrocytes. FARP2 is thought to regulate neurite remodeling by mediating the signaling pathways from membrane proteins to Rac. It is found in brain, lung, and testis, as well as embryonic hippocampal and cortical neurons []. They are composed of a N-terminal FERM domain, a proline-rich (PR) domain, Dbl-homology (DH), and two C-terminal PH domains.FRMD7 (FERM domain-containing protein 7) and Caenorhabditis elegans CFRM3 have a FERM domain that is closely related to that in FARP1 and FARP2. Both have unknown functions. They contain an N-terminal FERM domain, a PH domain, followed by a FA (FERM adjacent) domain []. FRMD7 has been linked to Idiopathic congenital nystagmus , an infant-onset disease with the typical features of bilateral ocular oscillations, visual impairment, and abnormal head movement [].
Publication
First Author: Mlechkovich G
Year: 2014
Journal: Sci Signal
Title: Distinct cytoplasmic domains in Plexin-A4 mediate diverse responses to semaphorin 3A in developing mammalian neurons.
Volume: 7
Issue: 316
Pages: ra24
Publication
First Author: Kitano K
Year: 2006
Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun
Title: Structure of dimerized radixin FERM domain suggests a novel masking motif in C-terminal residues 295-304.
Volume: 62
Issue: Pt 4
Pages: 340-5
Protein
Organism: Mus musculus
Length: 835  
Fragment?: true
Publication
First Author: Tepass U
Year: 2009
Journal: Curr Opin Genet Dev
Title: FERM proteins in animal morphogenesis.
Volume: 19
Issue: 4
Pages: 357-67
Protein
Organism: Mus musculus
Length: 1048  
Fragment?: false