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Search results 1 to 100 out of 108 for Fastk

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0.046s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Jourdain AA
Year: 2015
Journal: Cell Rep
Title: A mitochondria-specific isoform of FASTK is present in mitochondrial RNA granules and regulates gene expression and function.
Volume: 10
Issue: 7
Pages: 1110-21
Publication
First Author: García Del Río A
Year: 2018
Journal: J Immunol
Title: The Mitochondrial Isoform of FASTK Modulates Nonopsonic Phagocytosis of Bacteria by Macrophages via Regulation of Respiratory Complex I.
Volume: 201
Issue: 10
Pages: 2977-2985
Publication
First Author: Simarro M
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Fast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respiration.
Volume: 401
Issue: 3
Pages: 440-6
Publication
First Author: Zhang F
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Genetic ablation of Fas-activated serine/threonine kinase ameliorates obesity-related hepatic glucose and lipid metabolic disorders via sirtuin-1 signaling.
Volume: 529
Issue: 4
Pages: 1066-1072
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Simarro M
Year: 2010
Journal: J Immunol
Title: Fas-activated serine/threonine phosphoprotein promotes immune-mediated pulmonary inflammation.
Volume: 184
Issue: 9
Pages: 5325-32
Publication
First Author: Simarro M
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing.
Volume: 104
Issue: 27
Pages: 11370-5
GXD Expression    
Probe: MGI:5641037
Assay Type: RT-PCR
Annotation Date: 2015-06-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5641051
Age: postnatal day 15
Image: S7
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5641037
Assay Type: RT-PCR
Annotation Date: 2015-06-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5641051
Age: postnatal day 15
Image: S7
Detected: true
Specimen Num: 2
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853631
Note: kidney
Detected: true
Specimen Num: 11
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853622
Note: kidney
Detected: true
Specimen Num: 1
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853623
Note: kidney
Detected: true
Specimen Num: 2
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853624
Note: kidney
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1697428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853629
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3519728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853634
Detected: true
Specimen Num: 14
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Absent
Sex: Male
Emaps: EMAPS:1868128
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853637
Note: vas deferens
Detected: false
Specimen Num: 17
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853628
Note: vas deferens
Detected: true
Specimen Num: 8
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Absent
Sex: Female
Emaps: EMAPS:1898428
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853643
Detected: false
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1866628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853633
Detected: true
Specimen Num: 13
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853635
Detected: true
Specimen Num: 15
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853625
Detected: true
Specimen Num: 5
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1802528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853639
Note: chest bone
Detected: true
Specimen Num: 19
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853632
Detected: true
Specimen Num: 12
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853636
Detected: true
Specimen Num: 16
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853626
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853627
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853638
Detected: true
Specimen Num: 18
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691685
Age: postnatal adult
Image: UC Davis_1853630
Detected: true
Specimen Num: 10
Publication
First Author: Haines RR
Year: 2018
Journal: J Immunol
Title: The Histone Demethylase LSD1 Regulates B Cell Proliferation and Plasmablast Differentiation.
Volume: 201
Issue: 9
Pages: 2799-2811
Publication
First Author: West DB
Year: 2016
Journal: PLoS Genet
Title: Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression.
Volume: 12
Issue: 2
Pages: e1005691
Publication
First Author: Nakano Y
Year: 2012
Journal: PLoS Genet
Title: A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.
Volume: 8
Issue: 10
Pages: e1002966
Publication
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication
First Author: Jourdain AA
Year: 2017
Journal: Nucleic Acids Res
Title: The FASTK family of proteins: emerging regulators of mitochondrial RNA biology.
Volume: 45
Issue: 19
Pages: 10941-10947
GO Term
Protein
Organism: Mus musculus
Length: 101  
Fragment?: true
Protein
Organism: Mus musculus
Length: 606  
Fragment?: true
Protein Domain
Type: Domain
Description: This entry represents a conserved region of eukaryotic Fas-activated serine/threonine (FAST) kinases that contains several conserved leucine residues. This domain can be found in the FASTK family members, including FASTK, FASTKD1, FASTKD2 and FASTKD5. FAST kinase has been shown to be rapidly activated during Fas-mediated apoptosis, when it phosphorylates TIA-1, a nuclear RNA-binding protein that has been implicated as an effector of apoptosis []. However, a critical active site residues are not conserved within the family and their kinase activity has been questioned []. FASTK localizes to nucleus, cytosol and mitochondria. FASTKD1, FASTKD2 and FASTKD5 localizes to mitochondria. FASTK has been shown to bind ND6 mRNA and cooperate with the mitochondrial degradosome to ensure regulated ND6 mRNA biogenesis []. FASTKD1, FASTKD2 and FASTKD5 are involved in mitochondrial RNA stability [].
Publication
First Author: Li W
Year: 2004
Journal: Biochem Biophys Res Commun
Title: FAST is a BCL-X(L)-associated mitochondrial protein.
Volume: 318
Issue: 1
Pages: 95-102
Protein Domain
Type: Family
Description: This entry consists of proteins related to the eukaryotic Fas-activated serine/threonine (FAST) kinases that contain several conserved leucine residues. FAST kinase is rapidly activated during Fas-mediated apoptosis, when it phosphorylates TIA-1, a nuclear RNA-binding protein that has been implicated as an effector of apoptosis []. However, a critical active site residues are not conserved within the family and its kinase activity has been questioned. FASTK localizes to nucleus, cytosol and mitochondria. In mitochondria, FASTK concentrates in mitochondrial RNA granules, where it interacts with the G-rich se-quence factor 1 (GRSF1) and MT-ND6 mRNA [].
Publication
First Author: Tian Q
Year: 1995
Journal: J Exp Med
Title: Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis.
Volume: 182
Issue: 3
Pages: 865-74
Protein
Organism: Mus musculus
Length: 689  
Fragment?: false
Protein
Organism: Mus musculus
Length: 553  
Fragment?: false
Protein
Organism: Mus musculus
Length: 511  
Fragment?: false
Protein
Organism: Mus musculus
Length: 516  
Fragment?: false
Protein
Organism: Mus musculus
Length: 511  
Fragment?: false
Protein
Organism: Mus musculus
Length: 545  
Fragment?: false