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Search results 1 to 100 out of 116 for Fbxw8

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
26259 | FBXW8
Type: gene
Organism: human
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Gene
100294668 | fbxw8
Type: gene
Organism: frog, western clawed
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Gene
106557503 | FBXW8
Type: gene
Organism: dog, domestic
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Gene
304522 | Fbxw8
Type: gene
Organism: rat
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Gene
452285 | FBXW8
Type: gene
Organism: chimpanzee
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Gene
787118 | FBXW8
Type: gene
Organism: cattle
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Gene
417024 | FBXW8
Type: gene
Organism: chicken
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Gene
100136859 | fbxw8
Type: gene
Organism: zebrafish
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Gene
693388 | FBXW8
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1923041 | Fbxw8
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25790475 | J:242443
First Author: Halbach MV
Year: 2015
Journal: PLoS One
Title: Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated.
Volume: 10
Issue: 3
Pages: e0121089
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Publication
16880526 | J:111403
First Author: Tsunematsu R
Year: 2006
Journal: Mol Cell Biol
Title: Fbxw8 is essential for Cul1-Cul7 complex formation and for placental development.
Volume: 26
Issue: 16
Pages: 6157-69
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Publication
17998335 | J:130238
First Author: Tsutsumi T
Year: 2008
Journal: Mol Cell Biol
Title: Disruption of the Fbxw8 gene results in pre- and postnatal growth retardation in mice.
Volume: 28
Issue: 2
Pages: 743-51
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Publication
22956915 | J:188118
First Author: Damrath E
Year: 2012
Journal: PLoS Genet
Title: ATXN2-CAG42 sequesters PABPC1 into insolubility and induces FBXW8 in cerebellum of old ataxic knock-in mice.
Volume: 8
Issue: 8
Pages: e1002920
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Protein
Q9D5H7
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
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Publication
17332328 | J:118603
First Author: Skaar JR
Year: 2007
Journal: Cancer Res
Title: PARC and CUL7 form atypical cullin RING ligase complexes.
Volume: 67
Issue: 5
Pages: 2006-14
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Publication
21572988 | J:197512
First Author: Litterman N
Year: 2011
Journal: PLoS Biol
Title: An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning.
Volume: 9
Issue: 5
Pages: e1001060
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Protein Coding Gene
MGP_CAROLIEiJ_G0027649 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029993 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029957 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029896 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029968 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029688 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1923041 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030423 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029097 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029656 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029806 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029762 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029894 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029793 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030464 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028810 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024230 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028648 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3776748
Age: postnatal month 3
Specimen Label: Li-W
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3776748
Age: postnatal month 3
Specimen Label: Li-K
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3776748
Age: postnatal month 3
Specimen Label: Sp-W
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3776748
Age: postnatal month 3
Specimen Label: Sp-K
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3776748
Age: postnatal month 3
Specimen Label: Ki-W
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3776748
Age: postnatal month 3
Specimen Label: Ki-K
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3776748
Age: postnatal month 3
Specimen Label: Br-W
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3776748
Age: postnatal month 3
Specimen Label: Br-K
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3776748
Age: postnatal month 3
Specimen Label: Lu-W
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3776748
Age: postnatal month 3
Specimen Label: Lu-K
Detected: false
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3776748
Age: postnatal month 3
Specimen Label: He-W
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3776748
Age: postnatal month 3
Specimen Label: He-K
Detected: false
Specimen Num: 12
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:3776788
Age: embryonic day 18.5
Specimen Label: +/+
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:3776788
Age: embryonic day 18.5
Specimen Label: -/-
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:3776788
Age: embryonic day 18.5
Specimen Label: -/-
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:3776788
Age: embryonic day 18.5
Specimen Label: +/+
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:3776788
Age: embryonic day 18.5
Specimen Label: -/-
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3776747
Assay Type: Western blot
Annotation Date: 2008-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:3776788
Age: embryonic day 18.5
Specimen Label: -/-
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1737326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3776753
Age: embryonic day 18.5
Specimen Label: Not shown
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1619826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3776753
Age: embryonic day 18.5
Specimen Label: Not shown
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3776753
Age: embryonic day 18.5
Note: Expression is intense in the labyrinthine layer and moderate in the spongiotrophoblast layer.
Specimen Label: 3H
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3776753
Age: embryonic day 18.5
Note: Expression is intense in the labyrinthine layer and moderate in the spongiotrophoblast layer.
Specimen Label: 3I
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1721326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3776753
Age: embryonic day 18.5
Note: Expression is present in bone, especially in the epiphysis of tubular bone corresponding to cartilage. It is not present in the diaphysis, where the formation of bone has occured.
Specimen Label: 3E
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1721326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3776753
Age: embryonic day 18.5
Note: Expression is present in bone, especially in the epiphysis of tubular bone corresponding to cartilage. It is not present in the diaphysis, where the formation of bone has occured.
Specimen Label: 3F
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1770126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3776753
Age: embryonic day 18.5
Specimen Label: 3C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
       
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3526928
Stage: TS28
Assay Id: MGI:3776753
Age: embryonic day 18.5
Specimen Label: 3H
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
       
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3526928
Stage: TS28
Assay Id: MGI:3776753
Age: embryonic day 18.5
Specimen Label: 3I
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3598826
Pattern: Non-Uniform
Stage: TS26
Assay Id: MGI:3776753
Age: embryonic day 18.5
Note: There is high expression in the skeletal muscle, with intense staining observed in the intercostals and abdominal walls. Muscles in the extremities are also stained.
Specimen Label: 3C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3776753
Age: embryonic day 18.5
Note: The expression patterns are similar to those seen in -/- animals, but the levels of expression are reduced.
Specimen Label: Not shown
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3776753
Age: embryonic day 14.5
Note: The expression patterns are similar to those seen at E18.5.
Specimen Label: Not shown
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3271726
Stage: TS26
Assay Id: MGI:3776753
Age: embryonic day 18.5
Note: There is slight, if any, expression in the smooth muscle.
Specimen Label: 3C
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3269326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3776753
Age: embryonic day 18.5
Specimen Label: 3G
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3776753
Age: embryonic day 18.5
Specimen Label: Not shown
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2008-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3776753
Age: embryonic day 18.5
Note: There is little, if any, expression in the brain.
Specimen Label: Not shown
Detected: false
Specimen Num: 7
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Publication
24219910 | J:223190
First Author: Scheufele F
Year: 2014
Journal: Cell Signal
Title: Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling.
Volume: 26
Issue: 2
Pages: 233-239
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Publication
22124152 | J:183656
First Author: Kanie T
Year: 2012
Journal: Mol Cell Biol
Title: Genetic reevaluation of the role of F-box proteins in cyclin D1 degradation.
Volume: 32
Issue: 3
Pages: 590-605
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Publication
29153991 | J:259122
First Author: Bae KB
Year: 2017
Journal: Stem Cell Reports
Title: Serine 347 Phosphorylation by JNKs Negatively Regulates OCT4 Protein Stability in Mouse Embryonic Stem Cells.
Volume: 9
Issue: 6
Pages: 2050-2064
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Publication
23142081 | J:193983
First Author: Kim SJ
Year: 2012
Journal: Mol Cell
Title: mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8.
Volume: 48
Issue: 6
Pages: 875-87
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Publication
30735494 | J:271760
First Author: Gobé C
Year: 2019
Journal: PLoS Genet
Title: Dual role of DMXL2 in olfactory information transmission and the first wave of spermatogenesis.
Volume: 15
Issue: 2
Pages: e1007909
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Publication
15520277 | J:93441
First Author: Jin J
Year: 2004
Journal: Genes Dev
Title: Systematic analysis and nomenclature of mammalian F-box proteins.
Volume: 18
Issue: 21
Pages: 2573-80
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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