Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6251497 |
Assay Type: |
RT-PCR |
Annotation Date: |
2018-11-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:6251523 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
FcgR1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6251497 |
Assay Type: |
RT-PCR |
Annotation Date: |
2018-11-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684624 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6251524 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
FcgR1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6251497 |
Assay Type: |
RT-PCR |
Annotation Date: |
2018-11-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684626 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6251525 |
Age: |
embryonic day 19.5 |
|
|
Specimen Label: |
FcgR1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamaji K |
Year: |
2005 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Evidence for Cd101 but not Fcgr1 as candidate for type 1 diabetes locus, Idd10. |
Volume: |
331 |
Issue: |
2 |
Pages: |
536-42 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
330
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Prins JB |
Year: |
1993 |
Journal: |
Science |
Title: |
Linkage on chromosome 3 of autoimmune diabetes and defective Fc receptor for IgG in NOD mice. |
Volume: |
260 |
Issue: |
5108 |
Pages: |
695-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bersellini Farinotti A |
Year: |
2019 |
Journal: |
J Exp Med |
Title: |
Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons. |
Volume: |
216 |
Issue: |
8 |
Pages: |
1904-1924 |
|
•
•
•
•
•
|
Publication |
First Author: |
Podolin PL |
Year: |
1997 |
Journal: |
J Immunol |
Title: |
Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1. |
Volume: |
159 |
Issue: |
4 |
Pages: |
1835-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gavin AL |
Year: |
2000 |
Journal: |
Immunogenetics |
Title: |
Mouse FcgammaRI: identification and functional characterization of five new alleles. |
Volume: |
51 |
Issue: |
3 |
Pages: |
206-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang L |
Year: |
2019 |
Journal: |
J Clin Invest |
Title: |
Neuronal FcγRI mediates acute and chronic joint pain. |
Volume: |
129 |
Issue: |
9 |
Pages: |
3754-3769 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ikegami H |
Year: |
2003 |
Journal: |
Ann N Y Acad Sci |
Title: |
Congenic mapping and candidate sequencing of susceptibility genes for Type 1 diabetes in the NOD mouse. |
Volume: |
1005 |
|
Pages: |
196-204 |
|
•
•
•
•
•
|
Publication |
First Author: |
Scott CL |
Year: |
2018 |
Journal: |
Immunity |
Title: |
The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages. |
Volume: |
49 |
Issue: |
2 |
Pages: |
312-325.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kotov DI |
Year: |
2023 |
Journal: |
Cell |
Title: |
Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis. |
Volume: |
186 |
Issue: |
25 |
Pages: |
5536-5553.e22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Van Hove H |
Year: |
2019 |
Journal: |
Nat Neurosci |
Title: |
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment. |
Volume: |
22 |
Issue: |
6 |
Pages: |
1021-1035 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ben-Shaanan TL |
Year: |
2024 |
Journal: |
Dev Cell |
Title: |
Dermal TRPV1 innervations engage a macrophage- and fibroblast-containing pathway to activate hair growth in mice. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2023 |
Journal: |
Nature |
Title: |
Reprogramming tumour-associated macrophages to outcompete cancer cells. |
Volume: |
619 |
Issue: |
7970 |
Pages: |
616-623 |
|
•
•
•
•
•
|
Allele |
Name: |
deletion, Chr 3, Synbal 1 |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
No functional change |
|
•
•
•
•
•
|
Publication |
First Author: |
Mutant Mouse Regional Resource Centers |
Year: |
2004 |
Journal: |
Unpublished |
Title: |
Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Poole A |
Year: |
1997 |
Journal: |
EMBO J |
Title: |
The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen. |
Volume: |
16 |
Issue: |
9 |
Pages: |
2333-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamasaki S |
Year: |
2008 |
Journal: |
Nat Immunol |
Title: |
Mincle is an ITAM-coupled activating receptor that senses damaged cells. |
Volume: |
9 |
Issue: |
10 |
Pages: |
1179-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nimmerjahn F |
Year: |
2005 |
Journal: |
Immunity |
Title: |
FcgammaRIV: a novel FcR with distinct IgG subclass specificity. |
Volume: |
23 |
Issue: |
1 |
Pages: |
41-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mancardi DA |
Year: |
2008 |
Journal: |
J Clin Invest |
Title: |
FcgammaRIV is a mouse IgE receptor that resembles macrophage FcepsilonRI in humans and promotes IgE-induced lung inflammation. |
Volume: |
118 |
Issue: |
11 |
Pages: |
3738-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jakus Z |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Critical but overlapping role of FcgammaRIII and FcgammaRIV in activation of murine neutrophils by immobilized immune complexes. |
Volume: |
180 |
Issue: |
1 |
Pages: |
618-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Syed SN |
Year: |
2009 |
Journal: |
Eur J Immunol |
Title: |
Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a. |
Volume: |
39 |
Issue: |
12 |
Pages: |
3343-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
DiLillo DJ |
Year: |
2014 |
Journal: |
Nat Med |
Title: |
Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo. |
Volume: |
20 |
Issue: |
2 |
Pages: |
143-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Negishi-Koga T |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
Immune complexes regulate bone metabolism through FcRγ signalling. |
Volume: |
6 |
|
Pages: |
6637 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hogarth PM |
Year: |
1987 |
Journal: |
Immunogenetics |
Title: |
The mouse Fc receptor for IgG (Ly-17): molecular cloning and specificity. |
Volume: |
26 |
Issue: |
3 |
Pages: |
161-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hibbs ML |
Year: |
1986 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The murine Fc receptor for immunoglobulin: purification, partial amino acid sequence, and isolation of cDNA clones. |
Volume: |
83 |
Issue: |
18 |
Pages: |
6980-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhalerao J |
Year: |
1995 |
Journal: |
J Biol Chem |
Title: |
Molecular cloning, characterization, and genetic mapping of the cDNA coding for a novel secretory protein of mouse. Demonstration of alternative splicing in skin and cartilage. |
Volume: |
270 |
Issue: |
27 |
Pages: |
16385-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sears DW |
Year: |
1990 |
Journal: |
J Immunol |
Title: |
Molecular cloning and expression of the mouse high affinity Fc receptor for IgG. |
Volume: |
144 |
Issue: |
1 |
Pages: |
371-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Osman N |
Year: |
1992 |
Journal: |
J Immunol |
Title: |
Structure and mapping of the gene encoding mouse high affinity Fc gamma RI and chromosomal location of the human Fc gamma RI gene. |
Volume: |
148 |
Issue: |
5 |
Pages: |
1570-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quilliam AL |
Year: |
1993 |
Journal: |
Immunology |
Title: |
Biochemical characterization of murine Fc gamma RI. |
Volume: |
78 |
Issue: |
3 |
Pages: |
358-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barnes N |
Year: |
2002 |
Journal: |
Immunity |
Title: |
FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses. |
Volume: |
16 |
Issue: |
3 |
Pages: |
379-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ioan-Facsinay A |
Year: |
2002 |
Journal: |
Immunity |
Title: |
FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. |
Volume: |
16 |
Issue: |
3 |
Pages: |
391-402 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou H |
Year: |
2004 |
Journal: |
J Immunol |
Title: |
Microtubule-associated serine/threonine kinase-205 kDa and Fc gamma receptor control IL-12 p40 synthesis and NF-kappa B activation. |
Volume: |
172 |
Issue: |
4 |
Pages: |
2559-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ikegami H |
Year: |
1995 |
Journal: |
J Clin Invest |
Title: |
Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping. |
Volume: |
96 |
Issue: |
4 |
Pages: |
1936-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
van Vugt MJ |
Year: |
1996 |
Journal: |
Blood |
Title: |
FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo. |
Volume: |
87 |
Issue: |
9 |
Pages: |
3593-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
He L |
Year: |
2015 |
Journal: |
J Neurosci |
Title: |
Anti-Ganglioside Antibodies Induce Nodal and Axonal Injury via Fcγ Receptor-Mediated Inflammation. |
Volume: |
35 |
Issue: |
17 |
Pages: |
6770-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jönsson F |
Year: |
2012 |
Journal: |
Blood |
Title: |
Human FcγRIIA induces anaphylactic and allergic reactions. |
Volume: |
119 |
Issue: |
11 |
Pages: |
2533-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Godau J |
Year: |
2004 |
Journal: |
J Immunol |
Title: |
C5a initiates the inflammatory cascade in immune complex peritonitis. |
Volume: |
173 |
Issue: |
5 |
Pages: |
3437-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bruhns P |
Year: |
2003 |
Journal: |
Immunity |
Title: |
Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease. |
Volume: |
18 |
Issue: |
4 |
Pages: |
573-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Monteith AJ |
Year: |
2016 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Defects in lysosomal maturation facilitate the activation of innate sensors in systemic lupus erythematosus. |
Volume: |
113 |
Issue: |
15 |
Pages: |
E2142-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kang S |
Year: |
2016 |
Journal: |
J Immunol |
Title: |
Apoptotic Debris Accumulates on Hematopoietic Cells and Promotes Disease in Murine and Human Systemic Lupus Erythematosus. |
Volume: |
196 |
Issue: |
10 |
Pages: |
4030-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gray CA |
Year: |
2002 |
Journal: |
Eur J Immunol |
Title: |
A role for antibody and Fc receptor in the clearance of Brugia malayi microfilariae. |
Volume: |
32 |
Issue: |
4 |
Pages: |
1114-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hernández-Vargas P |
Year: |
2006 |
Journal: |
Circ Res |
Title: |
Fcgamma receptor deficiency confers protection against atherosclerosis in apolipoprotein E knockout mice. |
Volume: |
99 |
Issue: |
11 |
Pages: |
1188-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shores E |
Year: |
1997 |
Journal: |
J Immunol |
Title: |
Fc epsilonRI gamma can support T cell development and function in mice lacking endogenous TCR zeta-chain. |
Volume: |
159 |
Issue: |
1 |
Pages: |
222-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Strait RT |
Year: |
2011 |
Journal: |
J Exp Med |
Title: |
MHC class I-specific antibody binding to nonhematopoietic cells drives complement activation to induce transfusion-related acute lung injury in mice. |
Volume: |
208 |
Issue: |
12 |
Pages: |
2525-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bevaart L |
Year: |
2006 |
Journal: |
Cancer Res |
Title: |
The high-affinity IgG receptor, FcgammaRI, plays a central role in antibody therapy of experimental melanoma. |
Volume: |
66 |
Issue: |
3 |
Pages: |
1261-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boross P |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Destructive arthritis in the absence of both FcgammaRI and FcgammaRIII. |
Volume: |
180 |
Issue: |
7 |
Pages: |
5083-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stein MP |
Year: |
2000 |
Journal: |
J Immunol |
Title: |
C-reactive protein binding to murine leukocytes requires Fc gamma receptors. |
Volume: |
164 |
Issue: |
3 |
Pages: |
1514-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kozicky LK |
Year: |
2015 |
Journal: |
J Leukoc Biol |
Title: |
Intravenous immunoglobulin skews macrophages to an anti-inflammatory, IL-10-producing activation state. |
Volume: |
98 |
Issue: |
6 |
Pages: |
983-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hannani D |
Year: |
2014 |
Journal: |
Cell Death Differ |
Title: |
Contribution of humoral immune responses to the antitumor effects mediated by anthracyclines. |
Volume: |
21 |
Issue: |
1 |
Pages: |
50-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pilling D |
Year: |
2014 |
Journal: |
J Leukoc Biol |
Title: |
Inhibition of murine fibrocyte differentiation by cross-linked IgG is dependent on FcγRI. |
Volume: |
96 |
Issue: |
2 |
Pages: |
275-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zaytseva OO |
Year: |
2020 |
Journal: |
Front Cell Dev Biol |
Title: |
Fc-Linked IgG N-Glycosylation in FcγR Knock-Out Mice. |
Volume: |
8 |
|
Pages: |
67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saylor CA |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
Murine IgG1 and IgG3 isotype switch variants promote phagocytosis of Cryptococcus neoformans through different receptors. |
Volume: |
184 |
Issue: |
1 |
Pages: |
336-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chu N |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
IgG1 is pathogenic in Leishmania mexicana infection. |
Volume: |
185 |
Issue: |
11 |
Pages: |
6939-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bournazos S |
Year: |
2014 |
Journal: |
Cell |
Title: |
Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity. |
Volume: |
158 |
Issue: |
6 |
Pages: |
1243-1253 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mancardi DA |
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2011 |
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