Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
guinea pig |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6251500 |
Assay Type: |
RT-PCR |
Annotation Date: |
2018-11-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:6251529 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
FcgR3 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6251500 |
Assay Type: |
RT-PCR |
Annotation Date: |
2018-11-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684624 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6251530 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
FcgR3 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6251500 |
Assay Type: |
RT-PCR |
Annotation Date: |
2018-11-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684626 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6251531 |
Age: |
embryonic day 19.5 |
|
|
Specimen Label: |
FcgR3 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Ichii O |
Year: |
2008 |
Journal: |
Kidney Int |
Title: |
Altered balance of inhibitory and active Fc gamma receptors in murine autoimmune glomerulonephritis. |
Volume: |
74 |
Issue: |
3 |
Pages: |
339-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ferraro TN |
Year: |
2004 |
Journal: |
Mamm Genome |
Title: |
Fine mapping of a seizure susceptibility locus on mouse Chromosome 1: nomination of Kcnj10 as a causative gene. |
Volume: |
15 |
Issue: |
4 |
Pages: |
239-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamasaki S |
Year: |
2008 |
Journal: |
Nat Immunol |
Title: |
Mincle is an ITAM-coupled activating receptor that senses damaged cells. |
Volume: |
9 |
Issue: |
10 |
Pages: |
1179-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hurskainen TL |
Year: |
1999 |
Journal: |
J Biol Chem |
Title: |
ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family. |
Volume: |
274 |
Issue: |
36 |
Pages: |
25555-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mechetina LV |
Year: |
2002 |
Journal: |
Immunogenetics |
Title: |
Identification of CD16-2, a novel mouse receptor homologous to CD16/Fc gamma RIII. |
Volume: |
54 |
Issue: |
7 |
Pages: |
463-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nimmerjahn F |
Year: |
2005 |
Journal: |
Immunity |
Title: |
FcgammaRIV: a novel FcR with distinct IgG subclass specificity. |
Volume: |
23 |
Issue: |
1 |
Pages: |
41-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hirano M |
Year: |
2007 |
Journal: |
Nat Immunol |
Title: |
IgEb immune complexes activate macrophages through FcgammaRIV binding. |
Volume: |
8 |
Issue: |
7 |
Pages: |
762-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mancardi DA |
Year: |
2008 |
Journal: |
J Clin Invest |
Title: |
FcgammaRIV is a mouse IgE receptor that resembles macrophage FcepsilonRI in humans and promotes IgE-induced lung inflammation. |
Volume: |
118 |
Issue: |
11 |
Pages: |
3738-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jakus Z |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Critical but overlapping role of FcgammaRIII and FcgammaRIV in activation of murine neutrophils by immobilized immune complexes. |
Volume: |
180 |
Issue: |
1 |
Pages: |
618-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Syed SN |
Year: |
2009 |
Journal: |
Eur J Immunol |
Title: |
Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a. |
Volume: |
39 |
Issue: |
12 |
Pages: |
3343-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
DiLillo DJ |
Year: |
2014 |
Journal: |
Nat Med |
Title: |
Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo. |
Volume: |
20 |
Issue: |
2 |
Pages: |
143-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Negishi-Koga T |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
Immune complexes regulate bone metabolism through FcRγ signalling. |
Volume: |
6 |
|
Pages: |
6637 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ravetch JV |
Year: |
1986 |
Journal: |
Science |
Title: |
Structural heterogeneity and functional domains of murine immunoglobulin G Fc receptors. |
Volume: |
234 |
Issue: |
4777 |
Pages: |
718-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ioan-Facsinay A |
Year: |
2002 |
Journal: |
Immunity |
Title: |
FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. |
Volume: |
16 |
Issue: |
3 |
Pages: |
391-402 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huppi K |
Year: |
1989 |
Journal: |
Nucleic Acids Res |
Title: |
Sequence and organization of the mouse poly (ADP-ribose) polymerase gene. |
Volume: |
17 |
Issue: |
9 |
Pages: |
3387-401 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baniyash M |
Year: |
1989 |
Journal: |
J Biol Chem |
Title: |
The isolation and characterization of the murine T cell antigen receptor zeta chain gene. |
Volume: |
264 |
Issue: |
22 |
Pages: |
13252-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Feinman R |
Year: |
1994 |
Journal: |
EMBO J |
Title: |
PU.1 and an HLH family member contribute to the myeloid-specific transcription of the Fc gamma RIIIA promoter. |
Volume: |
13 |
Issue: |
16 |
Pages: |
3852-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mutant Mouse Regional Resource Centers |
Year: |
2004 |
Journal: |
Unpublished |
Title: |
Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Aloulou M |
Year: |
2012 |
Journal: |
Blood |
Title: |
IgG1 and IVIg induce inhibitory ITAM signaling through FcγRIII controlling inflammatory responses. |
Volume: |
119 |
Issue: |
13 |
Pages: |
3084-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jang JE |
Year: |
2012 |
Journal: |
Circ Res |
Title: |
Intravenous immunoglobulins modulate neutrophil activation and vascular injury through FcγRIII and SHP-1. |
Volume: |
110 |
Issue: |
8 |
Pages: |
1057-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park-Min KH |
Year: |
2007 |
Journal: |
Immunity |
Title: |
FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin. |
Volume: |
26 |
Issue: |
1 |
Pages: |
67-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Syenina A |
Year: |
2015 |
Journal: |
Elife |
Title: |
Dengue vascular leakage is augmented by mast cell degranulation mediated by immunoglobulin Fcγ receptors. |
Volume: |
4 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Obata-Ninomiya K |
Year: |
2013 |
Journal: |
J Exp Med |
Title: |
The skin is an important bulwark of acquired immunity against intestinal helminths. |
Volume: |
210 |
Issue: |
12 |
Pages: |
2583-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pozniak CD |
Year: |
2013 |
Journal: |
J Exp Med |
Title: |
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration. |
Volume: |
210 |
Issue: |
12 |
Pages: |
2553-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jönsson F |
Year: |
2012 |
Journal: |
Blood |
Title: |
Human FcγRIIA induces anaphylactic and allergic reactions. |
Volume: |
119 |
Issue: |
11 |
Pages: |
2533-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Balbino B |
Year: |
2017 |
Journal: |
J Allergy Clin Immunol |
Title: |
Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis. |
Volume: |
139 |
Issue: |
2 |
Pages: |
584-596.e10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Grimbaldeston MA |
Year: |
2007 |
Journal: |
Nat Immunol |
Title: |
Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B. |
Volume: |
8 |
Issue: |
10 |
Pages: |
1095-104 |
|
•
•
•
•
•
|
Publication |
First Author: |
Strait RT |
Year: |
2006 |
Journal: |
J Clin Invest |
Title: |
IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and Fc gamma RIIb cross-linking. |
Volume: |
116 |
Issue: |
3 |
Pages: |
833-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sadik CD |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and FcγR signaling. |
Volume: |
109 |
Issue: |
46 |
Pages: |
E3177-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Corr M |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
The role of FcgammaR signaling in the K/B x N serum transfer model of arthritis. |
Volume: |
169 |
Issue: |
11 |
Pages: |
6604-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Anderson AL |
Year: |
2006 |
Journal: |
Infect Immun |
Title: |
Pathogenesis of B-cell superantigen-induced immune complex-mediated inflammation. |
Volume: |
74 |
Issue: |
2 |
Pages: |
1196-203 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stokol T |
Year: |
2004 |
Journal: |
J Exp Med |
Title: |
C1q governs deposition of circulating immune complexes and leukocyte Fcgamma receptors mediate subsequent neutrophil recruitment. |
Volume: |
200 |
Issue: |
7 |
Pages: |
835-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Binstadt BA |
Year: |
2006 |
Journal: |
Nat Immunol |
Title: |
Particularities of the vasculature can promote the organ specificity of autoimmune attack. |
Volume: |
7 |
Issue: |
3 |
Pages: |
284-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nigrovic PA |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1. |
Volume: |
104 |
Issue: |
7 |
Pages: |
2325-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boross P |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
The inhibiting Fc receptor for IgG, FcγRIIB, is a modifier of autoimmune susceptibility. |
Volume: |
187 |
Issue: |
3 |
Pages: |
1304-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kikuchi S |
Year: |
2006 |
Journal: |
J Immunol |
Title: |
Contribution of NZB autoimmunity 2 to Y-linked autoimmune acceleration-induced monocytosis in association with murine systemic lupus. |
Volume: |
176 |
Issue: |
5 |
Pages: |
3240-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ren L |
Year: |
2016 |
Journal: |
J Biol Chem |
Title: |
Analysis of the Effects of the Bruton's tyrosine kinase (Btk) Inhibitor Ibrutinib on Monocyte Fcγ Receptor (FcγR) Function. |
Volume: |
291 |
Issue: |
6 |
Pages: |
3043-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bruhns P |
Year: |
2003 |
Journal: |
Immunity |
Title: |
Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease. |
Volume: |
18 |
Issue: |
4 |
Pages: |
573-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kang S |
Year: |
2016 |
Journal: |
J Immunol |
Title: |
Apoptotic Debris Accumulates on Hematopoietic Cells and Promotes Disease in Murine and Human Systemic Lupus Erythematosus. |
Volume: |
196 |
Issue: |
10 |
Pages: |
4030-9 |
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•
•
•
•
|
Publication |
First Author: |
Jodo S |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
Anti-CD95-induced lethality requires radioresistant Fcgamma RII+ cells. A novel mechanism for fulminant hepatic failure. |
Volume: |
278 |
Issue: |
9 |
Pages: |
7553-7 |
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•
•
•
•
|
Publication |
First Author: |
Seldin MF |
Year: |
1988 |
Journal: |
Curr Top Microbiol Immunol |
Title: |
A molecular genetic approach to gld "autoimmune" disease. |
Volume: |
137 |
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Pages: |
227-32 |
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•
•
•
•
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Publication |
First Author: |
Norkina O |
Year: |
2005 |
Journal: |
BMC Genet |
Title: |
Potential genetic modifiers of the cystic fibrosis intestinal inflammatory phenotype on mouse chromosomes 1, 9, and 10. |
Volume: |
6 |
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Pages: |
29 |
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•
•
•
•
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Publication |
First Author: |
Khmaladze Ia |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Mannan induces ROS-regulated, IL-17A-dependent psoriasis arthritis-like disease in mice. |
Volume: |
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Issue: |
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Pages: |
E3669-78 |
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Publication |
First Author: |
Frenkel D |
Year: |
2016 |
Journal: |
PLoS Pathog |
Title: |
Trypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B Cells. |
Volume: |
12 |
Issue: |
7 |
Pages: |
e1005733 |
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Publication |
First Author: |
Feng HM |
Year: |
2004 |
Journal: |
Infect Immun |
Title: |
Mechanisms of immunity to Ehrlichia muris: a model of monocytotropic ehrlichiosis. |
Volume: |
72 |
Issue: |
2 |
Pages: |
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•
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Publication |
First Author: |
Chouchakova N |
Year: |
2001 |
Journal: |
J Immunol |
Title: |
Fc gamma RIII-mediated production of TNF-alpha induces immune complex alveolitis independently of CXC chemokine generation. |
Volume: |
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8 |
Pages: |
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Publication |
First Author: |
Rivera J |
Year: |
2005 |
Journal: |
Infect Immun |
Title: |
Antibody-mediated protection against Cryptococcus neoformans pulmonary infection is dependent on B cells. |
Volume: |
73 |
Issue: |
2 |
Pages: |
1141-50 |
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•
•
•
•
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Publication |
First Author: |
Ozaki H |
Year: |
2009 |
Journal: |
Clin Immunol |
Title: |
Autoimmune thyroiditis in Fcgamma receptor-deficient nonobese diabetic mice. |
Volume: |
132 |
Issue: |
2 |
Pages: |
291-3 |
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•
•
•
•
|
Publication |
First Author: |
Hernández-Vargas P |
Year: |
2006 |
Journal: |
Circ Res |
Title: |
Fcgamma receptor deficiency confers protection against atherosclerosis in apolipoprotein E knockout mice. |
Volume: |
99 |
Issue: |
11 |
Pages: |
1188-96 |
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•
•
•
•
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Publication |
First Author: |
Zhu X |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
Scavenger receptor function of mouse Fcγ receptor III contributes to progression of atherosclerosis in apolipoprotein E hyperlipidemic mice. |
Volume: |
193 |
Issue: |
5 |
Pages: |
2483-95 |
|
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•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
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•
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•
•
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Publication |
First Author: |
Sanapala S |
Year: |
2012 |
Journal: |
Infect Immun |
Title: |
Perforin- and granzyme-mediated cytotoxic effector functions are essential for protection against Francisella tularensis following vaccination by the defined F. tularensis subsp. novicida ΔfopC vaccine strain. |
Volume: |
80 |
Issue: |
6 |
Pages: |
2177-85 |
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•
•
•
•
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Publication |
First Author: |
Shores E |
Year: |
1997 |
Journal: |
J Immunol |
Title: |
Fc epsilonRI gamma can support T cell development and function in mice lacking endogenous TCR zeta-chain. |
Volume: |
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Issue: |
1 |
Pages: |
222-30 |
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