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Search results 1 to 100 out of 371 for Fcgrt

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Hits by Strain

Hits by Category

Type Details Score
Gene
2217 | FCGRT
Type: gene
Organism: human
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Gene
338062 | FCGRT
Type: gene
Organism: cattle
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Gene
114674122 | FCGRT
Type: gene
Organism: macaque, rhesus
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Gene
29558 | Fcgrt
Type: gene
Organism: rat
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Gene
476414 | FCGRT
Type: gene
Organism: dog, domestic
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Gene
456208 | FCGRT
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:103017 | Fcgrt
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
33025844 | J:296090
First Author: Low BE
Year: 2020
Journal: MAbs
Title: Functional humanization of immunoglobulin heavy constant gamma 1 Fc domain human FCGRT transgenic mice.
Volume: 12
Issue: 1
Pages: 1829334
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Publication
24550358 | J:229512
First Author: Powner MB
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Expression of neonatal Fc receptor in the eye.
Volume: 55
Issue: 3
Pages: 1607-15
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Publication
20012394 | J:170668
 
First Author: Roopenian DC
Year: 2010
Journal: Methods Mol Biol
Title: Human FcRn transgenic mice for pharmacokinetic evaluation of therapeutic antibodies.
Volume: 602
Pages: 93-104
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Publication
35118359 | J:336495
First Author: Grevys A
Year: 2022
Journal: iScience
Title: Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life.
Volume: 25
Issue: 2
Pages: 103746
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Publication
24357670 | J:309917
First Author: Olaru F
Year: 2014
Journal: J Am Soc Nephrol
Title: Neonatal Fc receptor promotes immune complex-mediated glomerular disease.
Volume: 25
Issue: 5
Pages: 918-25
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Publication
12646614 | J:94189
First Author: Roopenian DC
Year: 2003
Journal: J Immunol
Title: The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgG-Fc-coupled drugs.
Volume: 170
Issue: 7
Pages: 3528-33
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Publication
27232760 | J:287666
First Author: Avery LB
Year: 2016
Journal: MAbs
Title: Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies.
Volume: 8
Issue: 6
Pages: 1064-78
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Publication
21256596 | J:170957
First Author: Wang W
Year: 2011
Journal: Mol Immunol
Title: Impact of methionine oxidation in human IgG1 Fc on serum half-life of monoclonal antibodies.
Volume: 48
Issue: 6-7
Pages: 860-6
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Publication
22193411 | J:179989
First Author: Stein C
Year: 2012
Journal: Mamm Genome
Title: Clinical chemistry of human FcRn transgenic mice.
Volume: 23
Issue: 3-4
Pages: 259-69
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Publication
36870576 | J:337544
 
First Author: Conner CM
Year: 2023
Journal: Biochem Pharmacol
Title: A precisely humanized FCRN transgenic mouse for preclinical pharmacokinetics studies.
Volume: 210
Pages: 115470
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Publication
24652290 | J:336471
First Author: Andersen JT
Year: 2014
Journal: J Biol Chem
Title: Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding.
Volume: 289
Issue: 19
Pages: 13492-502
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Publication
32461366 | J:289872
First Author: Borghi S
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: FcRn, but not FcγRs, drives maternal-fetal transplacental transport of human IgG antibodies.
Volume: 117
Issue: 23
Pages: 12943-12951
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Publication
36202799 | J:335978
First Author: Parzych EM
Year: 2022
Journal: Nat Commun
Title: DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2.
Volume: 13
Issue: 1
Pages: 5886
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Publication
33055243 | J:296594
 
First Author: Bern M
Year: 2020
Journal: Sci Transl Med
Title: An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics.
Volume: 12
Issue: 565
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Publication
25654695 | J:220803
First Author: Roopenian DC
Year: 2015
Journal: MAbs
Title: Albumin-deficient mouse models for studying metabolism of human albumin and pharmacokinetics of albumin-based drugs.
Volume: 7
Issue: 2
Pages: 344-51
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Publication
32313072 | J:288626
First Author: Nilsen J
Year: 2020
Journal: Commun Biol
Title: An intact C-terminal end of albumin is required for its long half-life in humans.
Volume: 3
Issue: 1
Pages: 181
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Publication
17077181 | J:133048
First Author: Petkova SB
Year: 2006
Journal: Int Immunol
Title: Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease.
Volume: 18
Issue: 12
Pages: 1759-69
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Publication
33032297 | J:300310
First Author: Bournazos S
Year: 2020
Journal: Nature
Title: Fc-optimized antibodies elicit CD8 immunity to viral respiratory infection.
Volume: 588
Issue: 7838
Pages: 485-490
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Publication
- | J:308648
     
First Author: Halwe S
Year: 2021
Journal: bioRxiv
Title: Intranasal administration of a monoclonal neutralizing antibody protects mice against SARS-CoV-2 infection.
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Publication
35604122 | J:336510
First Author: Wells AI
Year: 2022
Journal: mBio
Title: Enterovirus Replication and Dissemination Are Differentially Controlled by Type I and III Interferons in the Gastrointestinal Tract.
Volume: 13
Issue: 3
Pages: e0044322
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Publication
28330995 | J:242029
First Author: Pyzik M
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury.
Volume: 114
Issue: 14
Pages: E2862-E2871
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Protein Coding Gene
MGP_CAROLIEiJ_G0029696 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032199 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032178 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032114 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032190 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031906 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_103017 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032682 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031234 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031870 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032028 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031979 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032106 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032016 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032698 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030957 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031351 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0012921 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030794 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
7538537 | J:25532
First Author: Kandil E
Year: 1995
Journal: J Immunol
Title: Structural and phylogenetic analysis of the MHC class I-like Fc receptor gene.
Volume: 154
Issue: 11
Pages: 5907-18
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Publication
27225131 | J:336377
First Author: Iijima N
Year: 2016
Journal: Nature
Title: Access of protective antiviral antibody to neuronal tissues requires CD4 T-cell help.
Volume: 533
Issue: 7604
Pages: 552-6
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Publication
35687695 | J:338906
First Author: Sanidad KZ
Year: 2022
Journal: Sci Immunol
Title: Maternal gut microbiome-induced IgG regulates neonatal gut microbiome and immunity.
Volume: 7
Issue: 72
Pages: eabh3816
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Publication
21628593 | J:173310
First Author: Baker K
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells.
Volume: 108
Issue: 24
Pages: 9927-32
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Publication
33370294 | J:300128
First Author: Dylewski JF
Year: 2020
Journal: PLoS One
Title: Podocyte-specific knockout of the neonatal Fc receptor (FcRn) results in differential protection depending on the model of glomerulonephritis.
Volume: 15
Issue: 12
Pages: e0230401
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Publication
19188594 | J:146640
First Author: Montoyo HP
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice.
Volume: 106
Issue: 8
Pages: 2788-93
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Publication
25918233 | J:247168
First Author: Culina S
Year: 2015
Journal: Diabetes
Title: Materno-Fetal Transfer of Preproinsulin Through the Neonatal Fc Receptor Prevents Autoimmune Diabetes.
Volume: 64
Issue: 10
Pages: 3532-42
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Publication
37932271 | J:342391
First Author: Li W
Year: 2023
Journal: Nat Commun
Title: An FcRn-targeted mucosal vaccine against SARS-CoV-2 infection and transmission.
Volume: 14
Issue: 1
Pages: 7114
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Publication
33084569 | J:336343
   
First Author: Wang Z
Year: 2020
Journal: Elife
Title: A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch.
Volume: 9
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Publication
30326650 | J:295607
 
First Author: Li T
Year: 2018
Journal: Biomolecules
Title: FcRn Expression in Wildtype Mice, Transgenic Mice, and in Human Tissues.
Volume: 8
Issue: 4
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Publication
34731029 | J:332880
First Author: Pannek A
Year: 2022
Journal: Mol Biol Cell
Title: Dynamics of intracellular neonatal Fc receptor-ligand interactions in primary macrophages using biophysical fluorescence techniques.
Volume: 33
Issue: 1
Pages: ar6
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Publication
31695028 | J:336357
First Author: Lee CH
Year: 2019
Journal: Nat Commun
Title: An engineered human Fc domain that behaves like a pH-toggle switch for ultra-long circulation persistence.
Volume: 10
Issue: 1
Pages: 5031
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Publication
22570488 | J:188378
First Author: Andersen JT
Year: 2012
Journal: J Biol Chem
Title: Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life.
Volume: 287
Issue: 27
Pages: 22927-37
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Publication
25918417 | J:336376
First Author: Schoch A
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics.
Volume: 112
Issue: 19
Pages: 5997-6002
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Publication
20081867 | J:161273
First Author: Zalevsky J
Year: 2010
Journal: Nat Biotechnol
Title: Enhanced antibody half-life improves in vivo activity.
Volume: 28
Issue: 2
Pages: 157-9
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Publication
31444284 | J:336358
 
First Author: Toh WH
Year: 2019
Journal: J Cell Sci
Title: FcRn mediates fast recycling of endocytosed albumin and IgG from early macropinosomes in primary macrophages.
Volume: 133
Issue: 5
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Publication
27479095 | J:336360
First Author: Shan L
Year: 2016
Journal: PLoS One
Title: Generation and Characterization of an IgG4 Monomeric Fc Platform.
Volume: 11
Issue: 8
Pages: e0160345
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Publication
26539983 | J:245979
First Author: Sloan DD
Year: 2015
Journal: PLoS Pathog
Title: Targeting HIV Reservoir in Infected CD4 T Cells by Dual-Affinity Re-targeting Molecules (DARTs) that Bind HIV Envelope and Recruit Cytotoxic T Cells.
Volume: 11
Issue: 11
Pages: e1005233
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Publication
30808762 | J:272837
First Author: Morosky S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: The neonatal Fc receptor is a pan-echovirus receptor.
Volume: 116
Issue: 9
Pages: 3758-3763
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Publication
21690327 | J:178025
First Author: Patel DA
Year: 2011
Journal: J Immunol
Title: Neonatal Fc receptor blockade by Fc engineering ameliorates arthritis in a murine model.
Volume: 187
Issue: 2
Pages: 1015-22
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Publication
15124024 | J:95104
First Author: Akilesh S
Year: 2004
Journal: J Clin Invest
Title: The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease.
Volume: 113
Issue: 9
Pages: 1328-33
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Publication
17717602 | J:305927
First Author: Jaggi JS
Year: 2007
Journal: J Clin Invest
Title: Improved tumor imaging and therapy via i.v. IgG-mediated time-sequential modulation of neonatal Fc receptor.
Volume: 117
Issue: 9
Pages: 2422-30
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Publication
20362552 | J:160346
First Author: Nakata K
Year: 2010
Journal: Biochem Biophys Res Commun
Title: The transfer of maternal antigen-specific IgG regulates the development of allergic airway inflammation early in life in an FcRn-dependent manner.
Volume: 395
Issue: 2
Pages: 238-43
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Publication
30323819 | J:301702
 
First Author: Castaneda DC
Year: 2018
Journal: Front Immunol
Title: Lack of FcRn Impairs Natural Killer Cell Development and Functions in the Tumor Microenvironment.
Volume: 9
Pages: 2259
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Publication
23923029 | J:301615
First Author: Mohanty S
Year: 2013
Journal: PLoS One
Title: Abundant intracellular IgG in enterocytes and endoderm lacking FcRn.
Volume: 8
Issue: 7
Pages: e70863
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Publication
19661163 | J:166328
First Author: Sarav M
Year: 2009
Journal: J Am Soc Nephrol
Title: Renal FcRn reclaims albumin but facilitates elimination of IgG.
Volume: 20
Issue: 9
Pages: 1941-52
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Publication
31915378 | J:293354
First Author: Zheng W
Year: 2020
Journal: Nature
Title: Microbiota-targeted maternal antibodies protect neonates from enteric infection.
Volume: 577
Issue: 7791
Pages: 543-548
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Publication
24290911 | J:209206
First Author: Baker K
Year: 2013
Journal: Immunity
Title: Neonatal Fc receptor expression in dendritic cells mediates protective immunity against colorectal cancer.
Volume: 39
Issue: 6
Pages: 1095-107
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Publication
18198272 | J:131366
First Author: Akilesh S
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Podocytes use FcRn to clear IgG from the glomerular basement membrane.
Volume: 105
Issue: 3
Pages: 967-72
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Publication
18542899 | J:306440
First Author: Sesarman A
Year: 2008
Journal: J Mol Med (Berl)
Title: Neonatal Fc receptor deficiency protects from tissue injury in experimental epidermolysis bullosa acquisita.
Volume: 86
Issue: 8
Pages: 951-9
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Publication
16415101 | J:106617
First Author: Crowley H
Year: 2006
Journal: Int Immunol
Title: The MHC class I-related FcRn ameliorates murine Lyme arthritis.
Volume: 18
Issue: 3
Pages: 409-14
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Publication
22089027 | J:306754
First Author: Ben Suleiman Y
Year: 2012
Journal: Mucosal Immunol
Title: Neonatal Fc receptor for IgG (FcRn) expressed in the gastric epithelium regulates bacterial infection in mice.
Volume: 5
Issue: 1
Pages: 87-98
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Publication
17878355 | J:152349
First Author: Akilesh S
Year: 2007
Journal: J Immunol
Title: Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism.
Volume: 179
Issue: 7
Pages: 4580-8
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Publication
16210471 | J:106048
First Author: Kim J
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Albumin turnover: FcRn-mediated recycling saves as much albumin from degradation as the liver produces.
Volume: 290
Issue: 2
Pages: G352-60
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Publication
22042859 | J:180229
First Author: Bai Y
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Intracellular neutralization of viral infection in polarized epithelial cells by neonatal Fc receptor (FcRn)-mediated IgG transport.
Volume: 108
Issue: 45
Pages: 18406-11
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Publication
19234152 | J:146267
First Author: Kim J
Year: 2009
Journal: J Immunol
Title: FcRn in the yolk sac endoderm of mouse is required for IgG transport to fetus.
Volume: 182
Issue: 5
Pages: 2583-9
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Publication
10657638 | J:60330
First Author: Kacskovics I
Year: 2000
Journal: J Immunol
Title: Cloning and characterization of the bovine MHC class I-like Fc receptor.
Volume: 164
Issue: 4
Pages: 1889-97
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Publication
10998088 | J:64804
First Author: Mikulska JE
Year: 2000
Journal: Eur J Immunogenet
Title: Cloning and analysis of the gene encoding the human neonatal Fc receptor.
Volume: 27
Issue: 4
Pages: 231-40
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Publication
11090878 | J:66154
First Author: Adamski FM
Year: 2000
Journal: Mol Immunol
Title: Expression of the Fc receptor in the mammary gland during lactation in the marsupial Trichosurus vulpecula (brushtail possum).
Volume: 37
Issue: 8
Pages: 435-44
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Publication
7964511 | J:20509
First Author: Story CM
Year: 1994
Journal: J Exp Med
Title: A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetus.
Volume: 180
Issue: 6
Pages: 2377-81
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Publication
15644205 | J:96144
First Author: Zhou J
Year: 2005
Journal: J Mol Biol
Title: Conferring the binding properties of the mouse MHC class I-related receptor, FcRn, onto the human ortholog by sequential rounds of site-directed mutagenesis.
Volume: 345
Issue: 5
Pages: 1071-81
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Publication
16139891 | J:108118
First Author: Gurbaxani B
Year: 2006
Journal: Mol Immunol
Title: Analysis of a family of antibodies with different half-lives in mice fails to find a correlation between affinity for FcRn and serum half-life.
Volume: 43
Issue: 9
Pages: 1462-73
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Publication
16183124 | J:108120
First Author: Gurbaxani BM
Year: 2006
Journal: Mol Immunol
Title: Development of new models for the analysis of Fc-FcRn interactions.
Volume: 43
Issue: 9
Pages: 1379-89
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Publication
21368166 | J:170825
First Author: Li Z
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Transfer of IgG in the female genital tract by MHC class I-related neonatal Fc receptor (FcRn) confers protective immunity to vaginal infection.
Volume: 108
Issue: 11
Pages: 4388-93
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Publication
21402891 | J:172524
First Author: Liu X
Year: 2011
Journal: J Immunol
Title: The neonatal FcR-mediated presentation of immune-complexed antigen is associated with endosomal and phagosomal pH and antigen stability in macrophages and dendritic cells.
Volume: 186
Issue: 8
Pages: 4674-86
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Publication
31553647 | J:281664
First Author: Tonsawan P
Year: 2019
Journal: Am J Physiol Cell Physiol
Title: Knockout of the neonatal Fc receptor in cultured podocytes alters IL-6 signaling and the actin cytoskeleton.
Volume: 317
Issue: 5
Pages: C1048-C1060
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Publication
18599440 | J:344911
First Author: Qiao SW
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Dependence of antibody-mediated presentation of antigen on FcRn.
Volume: 105
Issue: 27
Pages: 9337-42
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Publication
37071647 | J:345543
First Author: Haddad G
Year: 2023
Journal: PLoS One
Title: Knockout of the neonatal Fc receptor alters immune complex trafficking and lysosomal function in cultured podocytes.
Volume: 18
Issue: 4
Pages: e0284636
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GXD Expression
GXD Expression
     
Probe: MGI:2654641
Assay Type: RT-PCR
Annotation Date: 2003-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:2654773
Age: embryonic day 1.0
Specimen Label: 2c
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7484732
Assay Type: RT-PCR
Annotation Date: 2023-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283426
Stage: TS26
Assay Id: MGI:7484764
Age: embryonic day 18.5
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7484732
Assay Type: RT-PCR
Annotation Date: 2023-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283426
Stage: TS26
Assay Id: MGI:7484764
Age: embryonic day 18.5
Specimen Label: KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2654641
Assay Type: RT-PCR
Annotation Date: 2003-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:2654773
Age: embryonic day 2.5
Specimen Label: 8c
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2654641
Assay Type: RT-PCR
Annotation Date: 2003-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2654757
Age: postnatal adult
Specimen Label: Uncut
Detected: true
Specimen Num: 1
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