|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 57 out of 57 for Fchsd1

0.019s

Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: F-BAR proteins been identified as important coordinators for membrane curvatures, which regulate cellular processes such as endocytosis, phagocytosis, adhesion and migration []. They bind to cell membrane via a N-terminal F-BAR domain, which associates with membrane phospholipids []. FCHSD1 and FCHSD2 are homologous proteins containing an amino-terminal F-BAR domain and two SH3 domains near their carboxyl-termini. FCHSD1 is expressed in cochlear sensory hair cells, and has been shown to bind via its F-BAR domain to the SH3 domain of Sorting Nexin 9, a BAR protein that has been shown to promote WASP-Arp2/3-dependent F-actin polymerization [].
Publication
First Author: Cao H
Year: 2013
Journal: PLoS One
Title: FCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro.
Volume: 8
Issue: 2
Pages: e56516
Publication  
First Author: Aspenström P
Year: 2009
Journal: Int Rev Cell Mol Biol
Title: Roles of F-BAR/PCH proteins in the regulation of membrane dynamics and actin reorganization.
Volume: 272
Pages: 1-31
Protein
Organism: Mus musculus
Length: 57  
Fragment?: false
Protein
Organism: Mus musculus
Length: 688  
Fragment?: false
Protein
Organism: Mus musculus
Length: 137  
Fragment?: true
Protein
Organism: Mus musculus
Length: 108  
Fragment?: true
Publication
First Author: Frost A
Year: 2009
Journal: Cell
Title: The BAR domain superfamily: membrane-molding macromolecules.
Volume: 137
Issue: 2
Pages: 191-6
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Becalska AN
Year: 2013
Journal: Mol Biol Cell
Title: Formation of membrane ridges and scallops by the F-BAR protein Nervous Wreck.
Volume: 24
Issue: 15
Pages: 2406-18
Publication
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
Publication      
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication
First Author: Katoh M
Year: 2004
Journal: Int J Mol Med
Title: Identification and characterization of human FCHSD1 and FCHSD2 genes in silico.
Volume: 13
Issue: 5
Pages: 749-54
Publication
First Author: Rodal AA
Year: 2008
Journal: J Neurosci
Title: Nervous wreck and Cdc42 cooperate to regulate endocytic actin assembly during synaptic growth.
Volume: 28
Issue: 33
Pages: 8316-25
Protein Domain
Type: Domain
Description: This entry represents the first SH3 domain found in the F-BAR and double SH3 domains proteins, including FCHSD1 and FCHSD2. These proteins have a common domain structure consisting of an N-terminal F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs), two SH3, and C-terminal proline-rich domains []. FCHSD1 and FCHSD2 are expressed in cochlear sensory hair cells. FCHSD2 interacts with WASP and N-WASP, and stimulates F-actin assembly in vitro. FCHSD1 does not bind to WASP, but binds via its F-BAR domain to the SH3 domain of Sorting Nexin 9, a BAR protein that has been shown to promote WASP-Arp2/3-dependent F-actin polymerization []. FCHSD2 has been implicated in receptor endocytosis and transport []. The insect protein nervous wreck, which acts as a regulator of synaptic growth signaling [], also contains this domain.
Publication  
First Author: Xu Y
Year: 2017
Journal: Front Biosci (Landmark Ed)
Title: Endocytosis and membrane receptor internalization: implication of F-BAR protein Carom.
Volume: 22
Pages: 1439-1457
Protein
Organism: Mus musculus
Length: 740  
Fragment?: false