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Search results 1 to 65 out of 65 for Fchsd1

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Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
89848 | FCHSD1
Type: gene
Organism: human
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Gene
100489010 | fchsd1
Type: gene
Organism: frog, western clawed
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Gene
307482 | Fchsd1
Type: gene
Organism: rat
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Gene
487187 | FCHSD1
Type: gene
Organism: dog, domestic
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Gene
462147 | FCHSD1
Type: gene
Organism: chimpanzee
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Gene
529296 | FCHSD1
Type: gene
Organism: cattle
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Gene
427616 | FCHSD1
Type: gene
Organism: chicken
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Gene
701267 | FCHSD1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2441771 | Fchsd1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR034935 | FCHSD1
Type: Family
Description: F-BAR proteins been identified as important coordinators for membrane curvatures, which regulate cellular processes such as endocytosis, phagocytosis, adhesion and migration []. They bind to cell membrane via a N-terminal F-BAR domain, which associates with membrane phospholipids []. FCHSD1 and FCHSD2 are homologous proteins containing an amino-terminal F-BAR domain and two SH3 domains near their carboxyl-termini. FCHSD1 is expressed in cochlear sensory hair cells, and has been shown to bind via its F-BAR domain to the SH3 domain of Sorting Nexin 9, a BAR protein that has been shown to promote WASP-Arp2/3-dependent F-actin polymerization [].
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Publication
23437151 | J:283192
First Author: Cao H
Year: 2013
Journal: PLoS One
Title: FCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro.
Volume: 8
Issue: 2
Pages: e56516
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Publication
34168078 | J:343811
 
First Author: Kawasaki T
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Loss of FCHSD1 leads to amelioration of chronic obstructive pulmonary disease.
Volume: 118
Issue: 26
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Publication
19121815 | -
 
First Author: Aspenström P
Year: 2009
Journal: Int Rev Cell Mol Biol
Title: Roles of F-BAR/PCH proteins in the regulation of membrane dynamics and actin reorganization.
Volume: 272
Pages: 1-31
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Protein
E9QA76
Organism: Mus musculus/domesticus
Length: 57  
Fragment?: false
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Protein
Q6PFY1
Organism: Mus musculus/domesticus
Length: 688  
Fragment?: false
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Protein
E9PVQ1
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: true
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Protein
E9Q363
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: true
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Publication
19379681 | -
First Author: Frost A
Year: 2009
Journal: Cell
Title: The BAR domain superfamily: membrane-molding macromolecules.
Volume: 137
Issue: 2
Pages: 191-6
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Protein Coding Gene
MGP_CAROLIEiJ_G0022205 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0024357 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0024324 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024293 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0024324 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0024090 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2441771 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024766 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023565 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0024060 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024190 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024156 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024274 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024187 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024815 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023309 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023628 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018938 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0023114 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
23761074 | J:269553
First Author: Becalska AN
Year: 2013
Journal: Mol Biol Cell
Title: Formation of membrane ridges and scallops by the F-BAR protein Nervous Wreck.
Volume: 24
Issue: 15
Pages: 2406-18
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Publication
20562862 | J:161922
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
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Publication
- | J:171883
     
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
15067381 | -
First Author: Katoh M
Year: 2004
Journal: Int J Mol Med
Title: Identification and characterization of human FCHSD1 and FCHSD2 genes in silico.
Volume: 13
Issue: 5
Pages: 749-54
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Publication
18701694 | -
First Author: Rodal AA
Year: 2008
Journal: J Neurosci
Title: Nervous wreck and Cdc42 cooperate to regulate endocytic actin assembly during synaptic growth.
Volume: 28
Issue: 33
Pages: 8316-25
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Protein Domain
IPR035460 | FCHSD_SH3_1
Type: Domain
Description: This entry represents the first SH3 domain found in the F-BAR and double SH3 domains proteins, including FCHSD1 and FCHSD2. These proteins have a common domain structure consisting of an N-terminal F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs), two SH3, and C-terminal proline-rich domains []. FCHSD1 and FCHSD2 are expressed in cochlear sensory hair cells. FCHSD2 interacts with WASP and N-WASP, and stimulates F-actin assembly in vitro. FCHSD1 does not bind to WASP, but binds via its F-BAR domain to the SH3 domain of Sorting Nexin 9, a BAR protein that has been shown to promote WASP-Arp2/3-dependent F-actin polymerization []. FCHSD2 has been implicated in receptor endocytosis and transport []. The insect protein nervous wreck, which acts as a regulator of synaptic growth signaling [], also contains this domain.
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Publication
28199211 | -
 
First Author: Xu Y
Year: 2017
Journal: Front Biosci (Landmark Ed)
Title: Endocytosis and membrane receptor internalization: implication of F-BAR protein Carom.
Volume: 22
Pages: 1439-1457
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Protein
Q3USJ8
Organism: Mus musculus/domesticus
Length: 740  
Fragment?: false
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