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Search results 1 to 92 out of 92 for Fchsd2

0.022s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: F-BAR proteins have been identified as important coordinators for membrane curvatures, which regulate cellular processes such as endocytosis, phagocytosis, adhesion and migration []. They bind to cell membrane via a N-terminal F-BAR domain, which associates with membrane phospholipids []. F-BAR and double SH3 domains protein 2 (FCHSD2), also known as carom, contains an N-terminal F-BAR domain and two SH3 domains at the C terminus []. It may mediate receptor endocytosis and transport [].
Publication
First Author: Cao H
Year: 2013
Journal: PLoS One
Title: FCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro.
Volume: 8
Issue: 2
Pages: e56516
Publication  
First Author: Xu Y
Year: 2017
Journal: Front Biosci (Landmark Ed)
Title: Endocytosis and membrane receptor internalization: implication of F-BAR protein Carom.
Volume: 22
Pages: 1439-1457
Publication  
First Author: Aspenström P
Year: 2009
Journal: Int Rev Cell Mol Biol
Title: Roles of F-BAR/PCH proteins in the regulation of membrane dynamics and actin reorganization.
Volume: 272
Pages: 1-31
Protein
Organism: Mus musculus
Length: 740  
Fragment?: false
Publication
First Author: Frost A
Year: 2009
Journal: Cell
Title: The BAR domain superfamily: membrane-molding macromolecules.
Volume: 137
Issue: 2
Pages: 191-6
Protein
Organism: Mus musculus
Length: 266  
Fragment?: true
Protein
Organism: Mus musculus
Length: 179  
Fragment?: true
Publication
First Author: Ohno H
Year: 2003
Journal: Oncogene
Title: Carom: a novel membrane-associated guanylate kinase-interacting protein with two SH3 domains.
Volume: 22
Issue: 52
Pages: 8422-31
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1837223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_05
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1837223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_06
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1837223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_07
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1837223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_08
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1837223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_09
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1837223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_10
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1837223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_11
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1837223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_13
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1837223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_14
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1837223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_15
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1837223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_16
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_03
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_04
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_05
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_06
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_07
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_16
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_17
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_18
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:1035501
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824819
Age: embryonic day 14.5
Image: euxassay_001442_19
Detected: true
Specimen Num: 16
Publication
First Author: Becalska AN
Year: 2013
Journal: Mol Biol Cell
Title: Formation of membrane ridges and scallops by the F-BAR protein Nervous Wreck.
Volume: 24
Issue: 15
Pages: 2406-18
Publication
First Author: Bulfone A
Year: 2005
Journal: J Neurosci
Title: Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
Volume: 25
Issue: 33
Pages: 7586-600
Publication
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 1
Pages: 35-48
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication
First Author: Katoh M
Year: 2004
Journal: Int J Mol Med
Title: Identification and characterization of human FCHSD1 and FCHSD2 genes in silico.
Volume: 13
Issue: 5
Pages: 749-54
Publication
First Author: Rodal AA
Year: 2008
Journal: J Neurosci
Title: Nervous wreck and Cdc42 cooperate to regulate endocytic actin assembly during synaptic growth.
Volume: 28
Issue: 33
Pages: 8316-25
Protein Domain
Type: Domain
Description: This entry represents the first SH3 domain found in the F-BAR and double SH3 domains proteins, including FCHSD1 and FCHSD2. These proteins have a common domain structure consisting of an N-terminal F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs), two SH3, and C-terminal proline-rich domains []. FCHSD1 and FCHSD2 are expressed in cochlear sensory hair cells. FCHSD2 interacts with WASP and N-WASP, and stimulates F-actin assembly in vitro. FCHSD1 does not bind to WASP, but binds via its F-BAR domain to the SH3 domain of Sorting Nexin 9, a BAR protein that has been shown to promote WASP-Arp2/3-dependent F-actin polymerization []. FCHSD2 has been implicated in receptor endocytosis and transport []. The insect protein nervous wreck, which acts as a regulator of synaptic growth signaling [], also contains this domain.
Protein Domain
Type: Family
Description: F-BAR proteins been identified as important coordinators for membrane curvatures, which regulate cellular processes such as endocytosis, phagocytosis, adhesion and migration []. They bind to cell membrane via a N-terminal F-BAR domain, which associates with membrane phospholipids []. FCHSD1 and FCHSD2 are homologous proteins containing an amino-terminal F-BAR domain and two SH3 domains near their carboxyl-termini. FCHSD1 is expressed in cochlear sensory hair cells, and has been shown to bind via its F-BAR domain to the SH3 domain of Sorting Nexin 9, a BAR protein that has been shown to promote WASP-Arp2/3-dependent F-actin polymerization [].
Publication
First Author: Almeida-Souza L
Year: 2018
Journal: Cell
Title: A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits.
Volume: 174
Issue: 2
Pages: 325-337.e14
Publication
First Author: Katoh M
Year: 2004
Journal: Int J Mol Med
Title: Identification and characterization of human FCHO2 and mouse Fcho2 genes in silico.
Volume: 14
Issue: 2
Pages: 327-31
Protein
Organism: Mus musculus
Length: 688  
Fragment?: false
Protein
Organism: Mus musculus
Length: 57  
Fragment?: false
Protein
Organism: Mus musculus
Length: 137  
Fragment?: true
Protein
Organism: Mus musculus
Length: 108  
Fragment?: true