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Search results 1 to 100 out of 148 for Ffar2

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0.041s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression  
Probe: MGI:4415954
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825960
Age: embryonic day 14.5
Image: Additional file 4 Ffar2
Specimen Label: Additional file 4 Ffar2
Detected: true
Specimen Num: 1
Publication
First Author: Chun E
Year: 2019
Journal: Immunity
Title: Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity.
Volume: 51
Issue: 5
Pages: 871-884.e6
Publication
First Author: Pan P
Year: 2018
Journal: Int J Cancer
Title: Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors.
Volume: 143
Issue: 4
Pages: 886-896
Publication
First Author: Nøhr MK
Year: 2013
Journal: Endocrinology
Title: GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neurons and FFAR2 in enteric leukocytes.
Volume: 154
Issue: 10
Pages: 3552-64
Publication
First Author: Sencio V
Year: 2020
Journal: Cell Rep
Title: Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production.
Volume: 30
Issue: 9
Pages: 2934-2947.e6
Publication
First Author: Bjursell M
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet.
Volume: 300
Issue: 1
Pages: E211-20
Publication
First Author: Fuller M
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: The short-chain fatty acid receptor, FFA2, contributes to gestational glucose homeostasis.
Volume: 309
Issue: 10
Pages: E840-51
Publication
First Author: Fuller M
Year: 2016
Journal: PLoS One
Title: FFA2 Contribution to Gestational Glucose Tolerance Is Not Disrupted by Antibiotics.
Volume: 11
Issue: 12
Pages: e0167837
Publication
First Author: Tolhurst G
Year: 2012
Journal: Diabetes
Title: Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2.
Volume: 61
Issue: 2
Pages: 364-71
Publication
First Author: Shimizu H
Year: 2019
Journal: Sci Rep
Title: Dietary short-chain fatty acid intake improves the hepatic metabolic condition via FFAR3.
Volume: 9
Issue: 1
Pages: 16574
Publication
First Author: Pan P
Year: 2017
Journal: Carcinogenesis
Title: Loss of free fatty acid receptor 2 enhances colonic adenoma development and reduces the chemopreventive effects of black raspberries in ApcMin/+ mice.
Volume: 38
Issue: 1
Pages: 86-93
Publication
First Author: Erny D
Year: 2015
Journal: Nat Neurosci
Title: Host microbiota constantly control maturation and function of microglia in the CNS.
Volume: 18
Issue: 7
Pages: 965-77
Publication
First Author: Engelstoft MS
Year: 2013
Journal: Mol Metab
Title: Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells.
Volume: 2
Issue: 4
Pages: 376-92
Publication
First Author: Tang C
Year: 2015
Journal: Nat Med
Title: Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes.
Volume: 21
Issue: 2
Pages: 173-7
Publication
First Author: Lavoie S
Year: 2020
Journal: Gastroenterology
Title: Expression of Free Fatty Acid Receptor 2 by Dendritic Cells Prevents Their Expression of Interleukin 27 and Is Required for Maintenance of Mucosal Barrier and Immune Response Against Colorectal Tumors in Mice.
Volume: 158
Issue: 5
Pages: 1359-1372.e9
Publication
First Author: Priyadarshini M
Year: 2015
Journal: Mol Endocrinol
Title: An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion.
Volume: 29
Issue: 7
Pages: 1055-66
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Ge H
Year: 2008
Journal: Endocrinology
Title: Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids.
Volume: 149
Issue: 9
Pages: 4519-26
Publication
First Author: Sina C
Year: 2009
Journal: J Immunol
Title: G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation.
Volume: 183
Issue: 11
Pages: 7514-22
Publication
First Author: Maslowski KM
Year: 2009
Journal: Nature
Title: Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43.
Volume: 461
Issue: 7268
Pages: 1282-6
Publication
First Author: Hudson BD
Year: 2013
Journal: J Biol Chem
Title: Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor.
Volume: 288
Issue: 24
Pages: 17296-312
Publication
First Author: Miyamoto J
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Ketone body receptor GPR43 regulates lipid metabolism under ketogenic conditions.
Volume: 116
Issue: 47
Pages: 23813-23821
Publication  
First Author: Kimura I
Year: 2013
Journal: Nat Commun
Title: The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43.
Volume: 4
Pages: 1829
Publication
First Author: Wu W
Year: 2017
Journal: Mucosal Immunol
Title: Microbiota metabolite short-chain fatty acid acetate promotes intestinal IgA response to microbiota which is mediated by GPR43.
Volume: 10
Issue: 4
Pages: 946-956
Publication
First Author: Forbes S
Year: 2015
Journal: Diabetes
Title: Selective FFA2 Agonism Appears to Act via Intestinal PYY to Reduce Transit and Food Intake but Does Not Improve Glucose Tolerance in Mouse Models.
Volume: 64
Issue: 11
Pages: 3763-71
Publication
First Author: Antunes KH
Year: 2019
Journal: Nat Commun
Title: Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response.
Volume: 10
Issue: 1
Pages: 3273
Publication
First Author: Andrade SP
Year: 1997
Journal: Microvasc Res
Title: Sponge-induced angiogenesis in mice and the pharmacological reactivity of the neovasculature quantitated by a fluorimetric method.
Volume: 54
Issue: 3
Pages: 253-61
Publication  
First Author: Galvão I
Year: 2018
Journal: Front Immunol
Title: The Metabolic Sensor GPR43 Receptor Plays a Role in the Control of Klebsiella pneumoniae Infection in the Lung.
Volume: 9
Pages: 142
Publication      
First Author: Canesso MCC
Year: 2023
Journal: J Invest Dermatol
Title: Dietary Fiber Improves Skin Wound Healing and Scar Formation through the Metabolite-Sensing Receptor GPR43.
Publication  
First Author: Villa SR
Year: 2016
Journal: Sci Rep
Title: Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival.
Volume: 6
Pages: 28159
Publication
First Author: Caengprasath N
Year: 2020
Journal: iScience
Title: Internalization-Dependent Free Fatty Acid Receptor 2 Signaling Is Essential for Propionate-Induced Anorectic Gut Hormone Release.
Volume: 23
Issue: 9
Pages: 101449
Publication
First Author: Zhao Y
Year: 2018
Journal: Mucosal Immunol
Title: GPR43 mediates microbiota metabolite SCFA regulation of antimicrobial peptide expression in intestinal epithelial cells via activation of mTOR and STAT3.
Volume: 11
Issue: 3
Pages: 752-762
Publication
First Author: McNelis JC
Year: 2015
Journal: Diabetes
Title: GPR43 Potentiates β-Cell Function in Obesity.
Volume: 64
Issue: 9
Pages: 3203-17
Publication
First Author: Yang W
Year: 2019
Journal: J Immunol
Title: Microbiota Metabolite Short-Chain Fatty Acids Facilitate Mucosal Adjuvant Activity of Cholera Toxin through GPR43.
Volume: 203
Issue: 1
Pages: 282-292
Publication
First Author: Lu J
Year: 2022
Journal: Int J Biol Sci
Title: GPR43 activation-mediated lipotoxicity contributes to podocyte injury in diabetic nephropathy by modulating the ERK/EGR1 pathway.
Volume: 18
Issue: 1
Pages: 96-111
Publication
First Author: Nakajima A
Year: 2017
Journal: PLoS One
Title: The short chain fatty acid receptor GPR43 regulates inflammatory signals in adipose tissue M2-type macrophages.
Volume: 12
Issue: 7
Pages: e0179696
Publication
First Author: D'Souza WN
Year: 2017
Journal: PLoS One
Title: Differing roles for short chain fatty acids and GPR43 agonism in the regulation of intestinal barrier function and immune responses.
Volume: 12
Issue: 7
Pages: e0180190
Publication
First Author: Kamp ME
Year: 2016
Journal: PLoS One
Title: G Protein-Coupled Receptor 43 Modulates Neutrophil Recruitment during Acute Inflammation.
Volume: 11
Issue: 9
Pages: e0163750
Publication
First Author: Sergeev E
Year: 2017
Journal: Sci Rep
Title: A single extracellular amino acid in Free Fatty Acid Receptor 2 defines antagonist species selectivity and G protein selection bias.
Volume: 7
Issue: 1
Pages: 13741
Publication
First Author: Schofield ZV
Year: 2020
Journal: FASEB J
Title: Acetate protects against intestinal ischemia-reperfusion injury independent of its cognate free fatty acid 2 receptor.
Volume: 34
Issue: 8
Pages: 10418-10430
GXD Expression    
Probe: MGI:5056070
Assay Type: RT-PCR
Annotation Date: 2011-08-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1844128
Stage: TS28
Assay Id: MGI:5056107
Age: postnatal day 49
Image: S1
Specimen Label: Gpr43 WT
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5056070
Assay Type: RT-PCR
Annotation Date: 2011-08-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1844128
Stage: TS28
Assay Id: MGI:5056108
Age: postnatal day 49
Image: S1
Specimen Label: Gpr43 WT
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4415954
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824833
Age: embryonic day 14.5
Image: euxassay_011368_06
Specimen Label: euxassay_011368_06
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4415954
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824833
Age: embryonic day 14.5
Image: euxassay_011368_07
Specimen Label: euxassay_011368_07
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4415954
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824833
Age: embryonic day 14.5
Image: euxassay_011368_08
Specimen Label: euxassay_011368_08
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4415954
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824833
Age: embryonic day 14.5
Image: euxassay_011368_09
Specimen Label: euxassay_011368_09
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4415954
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824833
Age: embryonic day 14.5
Image: euxassay_011368_10
Specimen Label: euxassay_011368_10
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4415954
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824833
Age: embryonic day 14.5
Image: euxassay_011368_11
Specimen Label: euxassay_011368_11
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4415954
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824833
Age: embryonic day 14.5
Image: euxassay_011368_12
Specimen Label: euxassay_011368_12
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4415954
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824833
Age: embryonic day 14.5
Image: euxassay_011368_13
Specimen Label: euxassay_011368_13
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4415954
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824833
Age: embryonic day 14.5
Image: euxassay_011368_14
Specimen Label: euxassay_011368_14
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4415954
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824833
Age: embryonic day 14.5
Image: euxassay_011368_15
Specimen Label: euxassay_011368_15
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4415954
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824833
Age: embryonic day 14.5
Image: euxassay_011368_16
Specimen Label: euxassay_011368_16
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4415954
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824833
Age: embryonic day 14.5
Image: euxassay_011368_17
Specimen Label: euxassay_011368_17
Detected: true
Specimen Num: 12
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692597
Age: postnatal adult
Image: JAX_1288155
Specimen Label: JAX_1288155
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692597
Age: postnatal adult
Image: JAX_1288153
Specimen Label: JAX_1288153
Detected: true
Specimen Num: 2
Publication
First Author: Xiu W
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Microbiota-derived short chain fatty acid promotion of Amphiregulin expression by dendritic cells is regulated by GPR43 and Blimp-1.
Volume: 533
Issue: 3
Pages: 282-288
Publication
First Author: Sun M
Year: 2018
Journal: Nat Commun
Title: Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis.
Volume: 9
Issue: 1
Pages: 3555
Publication
First Author: Tsugawa H
Year: 2020
Journal: PLoS Biol
Title: Short-chain fatty acids bind to apoptosis-associated speck-like protein to activate inflammasome complex to prevent Salmonella infection.
Volume: 18
Issue: 9
Pages: e3000813
Publication  
First Author: Li YJ
Year: 2023
Journal: Front Cell Dev Biol
Title: Short-chain fatty acids directly exert anti-inflammatory responses in podocytes and tubular epithelial cells exposed to high glucose.
Volume: 11
Pages: 1182570
Publication
First Author: Hayashi A
Year: 2021
Journal: J Immunol
Title: The Butyrate-Producing Bacterium Clostridium butyricum Suppresses Clostridioides difficile Infection via Neutrophil- and Antimicrobial Cytokine-Dependent but GPR43/109a-Independent Mechanisms.
Volume: 206
Issue: 7
Pages: 1576-1585
Publication
First Author: Li YJ
Year: 2020
Journal: J Am Soc Nephrol
Title: Dietary Fiber Protects against Diabetic Nephropathy through Short-Chain Fatty Acid-Mediated Activation of G Protein-Coupled Receptors GPR43 and GPR109A.
Volume: 31
Issue: 6
Pages: 1267-1281
Publication
First Author: Kaye DM
Year: 2020
Journal: Circulation
Title: Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease.
Volume: 141
Issue: 17
Pages: 1393-1403
Publication
First Author: Hudson BD
Year: 2012
Journal: J Biol Chem
Title: Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3.
Volume: 287
Issue: 49
Pages: 41195-209
Publication
First Author: Kim MH
Year: 2013
Journal: Gastroenterology
Title: Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice.
Volume: 145
Issue: 2
Pages: 396-406.e1-10
Publication
First Author: Hong YH
Year: 2005
Journal: Endocrinology
Title: Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43.
Volume: 146
Issue: 12
Pages: 5092-9
Publication
First Author: Teng F
Year: 2021
Journal: Cell Rep
Title: ILC3s control airway inflammation by limiting T cell responses to allergens and microbes.
Volume: 37
Issue: 8
Pages: 110051
Publication
First Author: Bachem A
Year: 2019
Journal: Immunity
Title: Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells.
Volume: 51
Issue: 2
Pages: 285-297.e5
Publication  
First Author: Mishra SP
Year: 2024
Journal: JCI Insight
Title: Abnormalities in microbiota/butyrate/FFAR3 signaling in aging gut impair brain function.
Volume: 9
Issue: 3
Publication
First Author: Prado C
Year: 2023
Journal: J Neuroinflammation
Title: GPR43 stimulation on TCRαβ(+) intraepithelial colonic lymphocytes inhibits the recruitment of encephalitogenic T-cells into the central nervous system and attenuates the development of autoimmunity.
Volume: 20
Issue: 1
Pages: 135
Publication
First Author: Mariño E
Year: 2017
Journal: Nat Immunol
Title: Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes.
Volume: 18
Issue: 5
Pages: 552-562
Publication
First Author: Smith PM
Year: 2013
Journal: Science
Title: The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis.
Volume: 341
Issue: 6145
Pages: 569-73
Publication
First Author: Luu M
Year: 2021
Journal: Nat Commun
Title: Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer.
Volume: 12
Issue: 1
Pages: 4077
Publication
First Author: Fujiwara H
Year: 2018
Journal: Nat Commun
Title: Microbial metabolite sensor GPR43 controls severity of experimental GVHD.
Volume: 9
Issue: 1
Pages: 3674