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Search results 1 to 100 out of 784 for Fgf23

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Type Details Score
Gene
8074 | FGF23
Type: gene
Organism: human
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Gene
530239 | FGF23
Type: gene
Organism: cattle
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Gene
428104 | FGF23
Type: gene
Organism: chicken
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Gene
494456 | fgf23
Type: gene
Organism: zebrafish
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Gene
710643 | FGF23
Type: gene
Organism: macaque, rhesus
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Gene
100233219 | fgf23
Type: gene
Organism: frog, western clawed
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Gene
170583 | Fgf23
Type: gene
Organism: rat
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Gene
611773 | FGF23
Type: gene
Organism: dog, domestic
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Gene
747164 | FGF23
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1891427 | Fgf23
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR028304 | FGF23
Type: Family
Description: Fibroblast growth factors (FGFs) [, ]are a family of multifunctional proteins, often referred to as 'promiscuous growth factors' due to their diverse actions on multiple cell types [, ]. FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The function of FGFs in developmental processes include mesoderm induction, anterior-posterior patterning, limb development, and neural induction and development. In mature tissues, they are involved in diverse processes including keratinocyte organisation and wound healing [, , , , , ]. FGF involvement is critical during normal development of both vertebrates and invertebrates, and irregularities in their function leads to a range of developmental defects [, , , ]. Fibroblast growth factors are heparin-binding proteins and interactions with cell-surface-associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs have internal pseudo-threefold symmetry (β-trefoil topology) []. There are currently over 20 different FGF family members that have been identified in mammals, all of which are structurally related signaling molecules [, ]. They exert their effects through four distinct membrane fibroblast growth factor receptors (FGFRs), FGFR1 to FGFR4 [], which belong to the tyrosine kinase superfamily. Upon binding to FGF, the receptors dimerize and their intracellular tyrosine kinase domains become active [].This entry represents fibroblast growth factor 23 (FGF23), which is secreted by osteoblasts and osteoclasts []. FGF23 acts on kidneys, where it decreases the expression of NPT2, a sodium-phosphate cotransporter in the proximal tubule []. FGF23 is responsible for phosphate metabolism, decreasing the reabsorption and increasing excretion of phosphate []. FGF23 is involved in the pathogenesis of three hypophosphatemic disorders; oncogenic osteomalacia (OOM), X-linked hypophosphatemia (XLH) and autosomal dominant hypophosphatemic rickets (ADHR). These conditions are characterised by hypophosphatemia, decreased renal phosphate reabsorption, normal or low serum calcitriol concentrations and defective skeletal mineralisation [, , ].
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Publication
11062477 | J:65463
First Author: ADHR Consortium.
Year: 2000
Journal: Nat Genet
Title: Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23.
Volume: 26
Issue: 3
Pages: 345-8
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Publication
11276432 | J:67832
First Author: Ornitz DM
Year: 2001
Journal: Genome Biol
Title: Fibroblast growth factors.
Volume: 2
Issue: 3
Pages: REVIEWS3005
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Publication
21985788 | J:178443
First Author: Faul C
Year: 2011
Journal: J Clin Invest
Title: FGF23 induces left ventricular hypertrophy.
Volume: 121
Issue: 11
Pages: 4393-408
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Publication
16449303 | J:110579
First Author: Liu S
Year: 2006
Journal: Am J Physiol Endocrinol Metab
Title: Pathogenic role of Fgf23 in Hyp mice.
Volume: 291
Issue: 1
Pages: E38-49
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Publication
18559986 | J:140067
First Author: Liu S
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Pathogenic role of Fgf23 in Dmp1-null mice.
Volume: 295
Issue: 2
Pages: E254-61
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Publication
37943605 | J:345899
 
First Author: Courbon G
Year: 2023
Journal: JCI Insight
Title: FGF23 directly inhibits osteoprogenitor differentiation in Dmp1-knockout mice.
Volume: 8
Issue: 24
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Publication
25051439 | J:218346
First Author: Ichikawa S
Year: 2014
Journal: Endocrinology
Title: Genetic rescue of glycosylation-deficient Fgf23 in the Galnt3 knockout mouse.
Volume: 155
Issue: 10
Pages: 3891-8
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Publication
29718273 | J:262478
First Author: Meo Burt P
Year: 2018
Journal: Endocrinology
Title: FGF23 Regulates Wnt/β-Catenin Signaling-Mediated Osteoarthritis in Mice Overexpressing High-Molecular-Weight FGF2.
Volume: 159
Issue: 6
Pages: 2386-2396
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Publication
31420162 | J:291415
First Author: Tamamura Y
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Notch signaling is involved in Fgf23 upregulation in osteocytes.
Volume: 518
Issue: 2
Pages: 233-238
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Publication
19556340 | J:225037
First Author: Liu S
Year: 2009
Journal: Mol Endocrinol
Title: Novel regulators of Fgf23 expression and mineralization in Hyp bone.
Volume: 23
Issue: 9
Pages: 1505-18
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Publication
17942069 | J:129885
First Author: Onishi T
Year: 2008
Journal: Arch Oral Biol
Title: Phex mutation causes overexpression of FGF23 in teeth.
Volume: 53
Issue: 2
Pages: 99-104
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Publication
32065590 | J:297941
First Author: Simic P
Year: 2020
Journal: J Clin Invest
Title: Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney.
Volume: 130
Issue: 3
Pages: 1513-1526
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Publication
24068282 | J:324434
First Author: Li Y
Year: 2013
Journal: Calcif Tissue Int
Title: FGF23 affects the lineage fate determination of mesenchymal stem cells.
Volume: 93
Issue: 6
Pages: 556-64
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Publication
31801907 | J:285265
 
First Author: Xiao Z
Year: 2019
Journal: JCI Insight
Title: FGF23 expression is stimulated in transgenic α-Klotho longevity mouse model.
Volume: 4
Issue: 23
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Publication
27871077 | J:324436
First Author: Umbach AT
Year: 2016
Journal: Kidney Blood Press Res
Title: Impact of Annexin A 7 Deficiency on FGF23 Plasma Concentrations.
Volume: 41
Issue: 6
Pages: 828-836
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Publication
23187128 | J:194201
First Author: Smith RC
Year: 2012
Journal: J Clin Invest
Title: Circulating αKlotho influences phosphate handling by controlling FGF23 production.
Volume: 122
Issue: 12
Pages: 4710-5
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Publication
24434184 | J:206448
First Author: Andrukhova O
Year: 2014
Journal: EMBO J
Title: FGF23 promotes renal calcium reabsorption through the TRPV5 channel.
Volume: 33
Issue: 3
Pages: 229-46
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Publication
24797667 | J:232068
First Author: Andrukhova O
Year: 2014
Journal: EMBO Mol Med
Title: FGF23 regulates renal sodium handling and blood pressure.
Volume: 6
Issue: 6
Pages: 744-59
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Publication
27498418 | J:249256
 
First Author: Andrukhova O
Year: 2016
Journal: Mol Cell Endocrinol
Title: Fgf23 and parathyroid hormone signaling interact in kidney and bone.
Volume: 436
Pages: 224-39
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Publication
18984852 | J:145616
First Author: Bai X
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Klotho ablation converts the biochemical and skeletal alterations in FGF23 (R176Q) transgenic mice to a Klotho-deficient phenotype.
Volume: 296
Issue: 1
Pages: E79-88
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Publication
14966565 | J:88172
First Author: Shimada T
Year: 2004
Journal: J Clin Invest
Title: Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism.
Volume: 113
Issue: 4
Pages: 561-8
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GXD Expression
GXD Expression
     
Probe: MGI:6172877
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190268
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Fgf23
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6172877
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190268
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Fgf23
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6172877
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6190268
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Fgf23
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6172877
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190268
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Fgf23
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6172877
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190268
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Fgf23
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6172877
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190268
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Fgf23
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6172877
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190268
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Fgf23
Detected: false
Specimen Num: 7
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Publication
33475190 | J:324471
First Author: Daryadel A
Year: 2021
Journal: FASEB J
Title: Systemic Jak1 activation provokes hepatic inflammation and imbalanced FGF23 production and cleavage.
Volume: 35
Issue: 2
Pages: e21302
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Publication
28183805 | J:274617
First Author: Kaludjerovic J
Year: 2017
Journal: FASEB J
Title: Klotho expression in long bones regulates FGF23 production during renal failure.
Volume: 31
Issue: 5
Pages: 2050-2064
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Publication
24302726 | J:324437
First Author: Kawai M
Year: 2014
Journal: J Biol Chem
Title: Sympathetic activation induces skeletal Fgf23 expression in a circadian rhythm-dependent manner.
Volume: 289
Issue: 3
Pages: 1457-66
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Publication
23577141 | J:199936
First Author: Lindberg K
Year: 2013
Journal: PLoS One
Title: Arterial klotho expression and FGF23 effects on vascular calcification and function.
Volume: 8
Issue: 4
Pages: e60658
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Publication
15869926 | J:123814
First Author: Yu X
Year: 2005
Journal: Bone
Title: Genetic dissection of phosphate- and vitamin D-mediated regulation of circulating Fgf23 concentrations.
Volume: 36
Issue: 6
Pages: 971-7
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Publication
23038738 | J:192371
First Author: Karaplis AC
Year: 2012
Journal: Endocrinology
Title: Mineralizing enthesopathy is a common feature of renal phosphate-wasting disorders attributed to FGF23 and is exacerbated by standard therapy in hyp mice.
Volume: 153
Issue: 12
Pages: 5906-17
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Publication
17174939 | J:117241
First Author: Fukuda T
Year: 2007
Journal: Biochem Biophys Res Commun
Title: FGF23 induces expression of two isoforms of NAB2, which are corepressors of Egr-1.
Volume: 353
Issue: 1
Pages: 147-51
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Publication
25243481 | J:223412
First Author: Lysaght AC
Year: 2014
Journal: PLoS One
Title: FGF23 deficiency leads to mixed hearing loss and middle ear malformation in mice.
Volume: 9
Issue: 9
Pages: e107681
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Publication
30830862 | J:288013
 
First Author: Clinkenbeard EL
Year: 2019
Journal: JCI Insight
Title: Increased FGF23 protects against detrimental cardio-renal consequences during elevated blood phosphate in CKD.
Volume: 4
Issue: 4
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Publication
18346951 | J:136859
First Author: Hollberg K
Year: 2008
Journal: Bone
Title: Osteoclast polarization is not required for degradation of bone matrix in rachitic FGF23 transgenic mice.
Volume: 42
Issue: 6
Pages: 1111-21
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Publication
23873717 | J:233246
First Author: Clinkenbeard EL
Year: 2014
Journal: J Bone Miner Res
Title: Neonatal iron deficiency causes abnormal phosphate metabolism by elevating FGF23 in normal and ADHR mice.
Volume: 29
Issue: 2
Pages: 361-9
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Publication
22249518 | -
First Author: Quarles LD
Year: 2012
Journal: Nat Rev Endocrinol
Title: Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism.
Volume: 8
Issue: 5
Pages: 276-86
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Publication
21346724 | -
 
First Author: Jüppner H
Year: 2011
Journal: Kidney Int Suppl
Title: Phosphate and FGF-23.
Issue: 121
Pages: S24-7
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Publication
18310961 | -
First Author: Fukumoto S
Year: 2008
Journal: Intern Med
Title: Physiological regulation and disorders of phosphate metabolism--pivotal role of fibroblast growth factor 23.
Volume: 47
Issue: 5
Pages: 337-43
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Publication
11409890 | -
First Author: Bowe AE
Year: 2001
Journal: Biochem Biophys Res Commun
Title: FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate.
Volume: 284
Issue: 4
Pages: 977-81
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Publication
37256933 | J:336374
First Author: Aprile A
Year: 2023
Journal: Sci Transl Med
Title: Inhibition of FGF23 is a therapeutic strategy to target hematopoietic stem cell niche defects in β-thalassemia.
Volume: 15
Issue: 698
Pages: eabq3679
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Publication
28900153 | J:256537
First Author: Slavic S
Year: 2017
Journal: Sci Rep
Title: Genetic Ablation of Fgf23 or Klotho Does not Modulate Experimental Heart Hypertrophy Induced by Pressure Overload.
Volume: 7
Issue: 1
Pages: 11298
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Publication
33853949 | J:332456
 
First Author: Radhakrishnan K
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Orphan nuclear receptor ERR-γ regulates hepatic FGF23 production in acute kidney injury.
Volume: 118
Issue: 16
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Publication
38479224 | J:346441
 
First Author: Jung YS
Year: 2024
Journal: Redox Biol
Title: ERRγ-inducible FGF23 promotes alcoholic liver injury through enhancing CYP2E1 mediated hepatic oxidative stress.
Volume: 71
Pages: 103107
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Publication
31758181 | J:287936
 
First Author: Matthias J
Year: 2020
Journal: Endocrinology
Title: Extra-Large Gα Protein (XLαs) Deficiency Causes Severe Adenine-Induced Renal Injury with Massive FGF23 Elevation.
Volume: 161
Issue: 1
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Publication
26428657 | J:237599
First Author: Fan Y
Year: 2016
Journal: FASEB J
Title: Parathyroid hormone 1 receptor is essential to induce FGF23 production and maintain systemic mineral ion homeostasis.
Volume: 30
Issue: 1
Pages: 428-40
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Publication
15998839 | J:101456
First Author: Shimada T
Year: 2005
Journal: Am J Physiol Renal Physiol
Title: Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism.
Volume: 289
Issue: 5
Pages: F1088-95
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Publication
15885032 | J:117597
First Author: Inoue Y
Year: 2005
Journal: Biochem J
Title: Role of the vitamin D receptor in FGF23 action on phosphate metabolism.
Volume: 390
Issue: Pt 1
Pages: 325-31
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Publication
17099775 | J:117377
First Author: Masuyama R
Year: 2006
Journal: J Clin Invest
Title: Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts.
Volume: 116
Issue: 12
Pages: 3150-9
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Publication
24348262 | J:207518
First Author: Olauson H
Year: 2013
Journal: PLoS Genet
Title: Parathyroid-specific deletion of Klotho unravels a novel calcineurin-dependent FGF23 signaling pathway that regulates PTH secretion.
Volume: 9
Issue: 12
Pages: e1003975
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Publication
32729975 | J:307389
First Author: Bøllehuus Hansen L
Year: 2020
Journal: FASEB J
Title: Influence of FGF23 and Klotho on male reproduction: Systemic vs direct effects.
Volume: 34
Issue: 9
Pages: 12436-12449
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Publication
22970174 | J:286318
First Author: Dai B
Year: 2012
Journal: PLoS One
Title: A comparative transcriptome analysis identifying FGF23 regulated genes in the kidney of a mouse CKD model.
Volume: 7
Issue: 9
Pages: e44161
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Publication
25053401 | J:215598
First Author: Silswal N
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: FGF23 directly impairs endothelium-dependent vasorelaxation by increasing superoxide levels and reducing nitric oxide bioavailability.
Volume: 307
Issue: 5
Pages: E426-36
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Publication
23443925 | J:196066
First Author: Touchberry CD
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: FGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy.
Volume: 304
Issue: 8
Pages: E863-73
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Publication
27035636 | J:232398
First Author: Murali SK
Year: 2016
Journal: PLoS Biol
Title: Excessive Osteocytic Fgf23 Secretion Contributes to Pyrophosphate Accumulation and Mineralization Defect in Hyp Mice.
Volume: 14
Issue: 4
Pages: e1002427
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Publication
23235154 | J:315922
First Author: Kawai M
Year: 2013
Journal: J Biol Chem
Title: FGF23 suppresses chondrocyte proliferation in the presence of soluble α-Klotho both in vitro and in vivo.
Volume: 288
Issue: 4
Pages: 2414-27
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Publication
26235988 | J:324438
First Author: Murali SK
Year: 2016
Journal: J Bone Miner Res
Title: FGF23 Regulates Bone Mineralization in a 1,25(OH)2 D3 and Klotho-Independent Manner.
Volume: 31
Issue: 1
Pages: 129-42
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Publication
28425622 | J:312342
First Author: Kamiya N
Year: 2017
Journal: J Bone Miner Res
Title: Targeted Disruption of NF1 in Osteocytes Increases FGF23 and Osteoid With Osteomalacia-like Bone Phenotype.
Volume: 32
Issue: 8
Pages: 1716-1726
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Publication
25007710 | J:215638
 
First Author: Reilly AM
Year: 2014
Journal: Bone
Title: Nicotinamide treatment in a murine model of familial tumoral calcinosis reduces serum Fgf23 and raises heart calcium.
Volume: 67
Pages: 139-44
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Publication
24259513 | J:206158
First Author: Gattineni J
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Regulation of renal phosphate transport by FGF23 is mediated by FGFR1 and FGFR4.
Volume: 306
Issue: 3
Pages: F351-8
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Publication
22615579 | J:185208
First Author: Wang X
Year: 2012
Journal: PLoS Genet
Title: Inactivation of a novel FGF23 regulator, FAM20C, leads to hypophosphatemic rickets in mice.
Volume: 8
Issue: 5
Pages: e1002708
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Publication
33150413 | J:298845
 
First Author: Sellars KB
Year: 2021
Journal: Endocrinology
Title: Murine Fetal Serum Phosphorus is Set Independent of FGF23 and PTH, Except in the Presence of Maternal Phosphate Loading.
Volume: 162
Issue: 1
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Publication
29073196 | J:246521
First Author: Flamme I
Year: 2017
Journal: PLoS One
Title: FGF23 expression in rodents is directly induced via erythropoietin after inhibition of hypoxia inducible factor proline hydroxylase.
Volume: 12
Issue: 10
Pages: e0186979
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Publication
19966287 | J:156501
First Author: Goetz R
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation.
Volume: 107
Issue: 1
Pages: 407-12
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Publication
28794403 | J:309449
First Author: Sakurai A
Year: 2017
Journal: Biomed Res
Title: Chronological immunolocalization of sclerostin and FGF23 in the mouse metaphyseal trabecular and cortical bone.
Volume: 38
Issue: 4
Pages: 257-267
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Protein
Q9EPC2
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: false
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Protein
Q3U1V5
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: false
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Protein
Q0VBJ8
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: false
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Publication
22370560 | J:197702
First Author: Wu X
Year: 2012
Journal: J Mol Biol
Title: A unique FGF23 with the ability to activate FGFR signaling through both αKlotho and βKlotho.
Volume: 418
Issue: 1-2
Pages: 82-9
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Publication
22647968 | J:192420
First Author: Andrukhova O
Year: 2012
Journal: Bone
Title: FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2-SGK1 signaling pathway.
Volume: 51
Issue: 3
Pages: 621-8
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Publication
29635291 | J:261402
First Author: Liu ES
Year: 2018
Journal: Endocrinology
Title: Increased Circulating FGF23 Does Not Lead to Cardiac Hypertrophy in the Male Hyp Mouse Model of XLH.
Volume: 159
Issue: 5
Pages: 2165-2172
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Publication
31097591 | J:276542
First Author: Takashi Y
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Activation of unliganded FGF receptor by extracellular phosphate potentiates proteolytic protection of FGF23 by its O-glycosylation.
Volume: 116
Issue: 23
Pages: 11418-11427
•
•
•
•
•
Publication
33731726 | J:304841
First Author: Egli-Spichtig D
Year: 2021
Journal: Sci Rep
Title: Renal Dnase1 expression is regulated by FGF23 but loss of Dnase1 does not alter renal phosphate handling.
Volume: 11
Issue: 1
Pages: 6175
•
•
•
•
•
Publication
24601885 | J:210730
First Author: Ma Y
Year: 2014
Journal: Endocrinology
Title: Neither absence nor excess of FGF23 disturbs murine fetal-placental phosphorus homeostasis or prenatal skeletal development and mineralization.
Volume: 155
Issue: 5
Pages: 1596-605
•
•
•
•
•
Publication
22294750 | J:183813
First Author: Streicher C
Year: 2012
Journal: Endocrinology
Title: Long-term Fgf23 deficiency does not influence aging, glucose homeostasis, or fat metabolism in mice with a nonfunctioning vitamin D receptor.
Volume: 153
Issue: 4
Pages: 1795-805
•
•
•
•
•
Publication
22031097 | J:329780
First Author: Stubbs JR
Year: 2012
Journal: J Bone Miner Res
Title: Longitudinal evaluation of FGF23 changes and mineral metabolism abnormalities in a mouse model of chronic kidney disease.
Volume: 27
Issue: 1
Pages: 38-46
•
•
•
•
•
Publication
19213845 | J:151805
First Author: Ichikawa S
Year: 2009
Journal: Endocrinology
Title: Ablation of the Galnt3 gene leads to low-circulating intact fibroblast growth factor 23 (Fgf23) concentrations and hyperphosphatemia despite increased Fgf23 expression.
Volume: 150
Issue: 6
Pages: 2543-50
•
•
•
•
•
Publication
19933269 | J:159949
First Author: Xiao L
Year: 2010
Journal: J Biol Chem
Title: Nuclear isoforms of fibroblast growth factor 2 are novel inducers of hypophosphatemia via modulation of FGF23 and KLOTHO.
Volume: 285
Issue: 4
Pages: 2834-46
•
•
•
•
•
Publication
27929669 | J:246176
First Author: Ma Y
Year: 2017
Journal: Endocrinology
Title: FGF23 Is Not Required to Regulate Fetal Phosphorus Metabolism but Exerts Effects Within 12 Hours After Birth.
Volume: 158
Issue: 2
Pages: 252-263
•
•
•
•
•
Publication
22930691 | J:225089
First Author: Martin A
Year: 2012
Journal: Mol Endocrinol
Title: Overexpression of the DMP1 C-terminal fragment stimulates FGF23 and exacerbates the hypophosphatemic rickets phenotype in Hyp mice.
Volume: 26
Issue: 11
Pages: 1883-95
•
•
•
•
•
Publication
19515808 | J:150719
First Author: Gattineni J
Year: 2009
Journal: Am J Physiol Renal Physiol
Title: FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.
Volume: 297
Issue: 2
Pages: F282-91
•
•
•
•
•
Publication
17848631 | J:129380
First Author: Liu S
Year: 2007
Journal: Am J Physiol Endocrinol Metab
Title: Distinct roles for intrinsic osteocyte abnormalities and systemic factors in regulation of FGF23 and bone mineralization in Hyp mice.
Volume: 293
Issue: 6
Pages: E1636-44
•
•
•
•
•
Publication
26751835 | J:323234
First Author: Liu ES
Year: 2016
Journal: J Bone Miner Res
Title: 1,25-Dihydroxyvitamin D Alone Improves Skeletal Growth, Microarchitecture, and Strength in a Murine Model of XLH, Despite Enhanced FGF23 Expression.
Volume: 31
Issue: 5
Pages: 929-39
•
•
•
•
•
Publication
2549857 | -
 
First Author: Burgess WH
Year: 1989
Journal: Annu Rev Biochem
Title: The heparin-binding (fibroblast) growth factor family of proteins.
Volume: 58
Pages: 575-606
•
•
•
•
•
Publication
7583099 | -
First Author: Wilkie AO
Year: 1995
Journal: Curr Biol
Title: Functions of fibroblast growth factors and their receptors.
Volume: 5
Issue: 5
Pages: 500-7
•
•
•
•
•
Publication
3072709 | -
First Author: Thomas KA
Year: 1988
Journal: Trends Biochem Sci
Title: Transforming potential of fibroblast growth factor genes.
Volume: 13
Issue: 9
Pages: 327-8
•
•
•
•
•




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