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Search results 1 to 100 out of 1376 for Fgf4

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Type Details Score
Gene
2249 | FGF4
Type: gene
Organism: human
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Gene
618474 | FGF4
Type: gene
Organism: cattle
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Gene
428857 | FGF4
Type: gene
Organism: chicken
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Gene
570435 | fgf4
Type: gene
Organism: zebrafish
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Gene
709016 | FGF4
Type: gene
Organism: macaque, rhesus
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Gene
100217325 | fgf4
Type: gene
Organism: frog, western clawed
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Gene
116499 | Fgf4
Type: gene
Organism: rat
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Gene
483680 | FGF4
Type: gene
Organism: dog, domestic
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Gene
747727 | FGF4
Type: gene
Organism: chimpanzee
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Protein Domain
IPR028239 | FGF4
Type: Family
Description: Fibroblast growth factors (FGFs) [, ]are a family of multifunctional proteins, often referred to as 'promiscuous growth factors' due to their diverse actions on multiple cell types [, ]. FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The function of FGFs in developmental processes include mesoderm induction, anterior-posterior patterning, limb development, and neural induction and development. In mature tissues, they are involved in diverse processes including keratinocyte organisation and wound healing [, , , , , ]. FGF involvement is critical during normal development of both vertebrates and invertebrates, and irregularities in their function leads to a range of developmental defects [, , , ]. Fibroblast growth factors are heparin-binding proteins and interactions with cell-surface-associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs have internal pseudo-threefold symmetry (β-trefoil topology) []. There are currently over 20 different FGF family members that have been identified in mammals, all of which are structurally related signaling molecules [, ]. They exert their effects through four distinct membrane fibroblast growth factor receptors (FGFRs), FGFR1 to FGFR4 [], which belong to the tyrosine kinase superfamily. Upon binding to FGF, the receptors dimerize and their intracellular tyrosine kinase domains become active [].This entry represents fibroblast growth factor 4 (FGF4), also known as heparin secretory transforming protein 1. This protein plays an important role in the regulation of embryonic development, cell proliferation and differentiation []. Studies on the mouse protein suggest a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway [, ].
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Protein Coding Gene
MGI:95518 | Fgf4
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
109117330 | LOC109117330
Type: gene
Organism: human
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Gene
109117331 | LOC109117331
Type: gene
Organism: human
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Publication
9477322 | J:47321
First Author: Kim HJ
Year: 1998
Journal: Development
Title: FGF-, BMP- and Shh-mediated signalling pathways in the regulation of cranial suture morphogenesis and calvarial bone development.
Volume: 125
Issue: 7
Pages: 1241-51
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Publication
23172713 | J:320733
First Author: Yan XR
Year: 2013
Journal: Cell Biochem Funct
Title: Expression of FGF4 mRNA is mediated by mating behaviours in mice.
Volume: 31
Issue: 6
Pages: 526-31
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Publication
21368122 | J:170831
First Author: Naiche LA
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: FGF4 and FGF8 comprise the wavefront activity that controls somitogenesis.
Volume: 108
Issue: 10
Pages: 4018-23
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Publication
36702076 | J:346350
 
First Author: Jiang H
Year: 2023
Journal: Int Immunopharmacol
Title: FGF4 improves hepatocytes ferroptosis in autoimmune hepatitis mice via activation of CISD3.
Volume: 116
Pages: 109762
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Publication
34719815 | J:324241
First Author: Zelarayan L
Year: 2022
Journal: Dev Dyn
Title: Inactivation of Fgf3 and Fgf4 within the Fgf3/Fgf4/Fgf15 gene cluster reveals their redundant requirement for mouse inner ear induction and embryonic survival.
Volume: 251
Issue: 5
Pages: 877-884
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Publication
12748966 | J:83729
First Author: Goldin SN
Year: 2003
Journal: Genesis
Title: Paracrine action of FGF4 during periimplantation development maintains trophectoderm and primitive endoderm.
Volume: 36
Issue: 1
Pages: 40-7
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Publication
10802662 | J:61886
First Author: Sun X
Year: 2000
Journal: Nat Genet
Title: Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development.
Volume: 25
Issue: 1
Pages: 83-6
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Publication
15328019 | J:93163
First Author: Boulet AM
Year: 2004
Journal: Dev Biol
Title: The roles of Fgf4 and Fgf8 in limb bud initiation and outgrowth.
Volume: 273
Issue: 2
Pages: 361-72
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Publication
11430695 | J:71525
First Author: Hayes C
Year: 2001
Journal: J Anat
Title: Retinoic acid specifically downregulates Fgf4 and inhibits posterior cell proliferation in the developing mouse autopod.
Volume: 198
Issue: Pt 5
Pages: 561-8
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Publication
26498204 | J:316798
First Author: Ogawa H
Year: 2016
Journal: J Reprod Dev
Title: Cell proliferation potency is independent of FGF4 signaling in trophoblast stem cells derived from androgenetic embryos.
Volume: 62
Issue: 1
Pages: 51-8
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Publication
19531481 | J:153457
First Author: Gao F
Year: 2009
Journal: J Biol Chem
Title: PARP1 poly(ADP-ribosyl)ates Sox2 to control Sox2 protein levels and FGF4 expression during embryonic stem cell differentiation.
Volume: 284
Issue: 33
Pages: 22263-73
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Publication
9851853 | J:51545
First Author: Fraidenraich D
Year: 1998
Journal: Dev Biol
Title: Distinct regulatory elements govern Fgf4 gene expression in the mouse blastocyst, myotomes, and developing limb.
Volume: 204
Issue: 1
Pages: 197-209
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Publication
16308330 | J:104411
First Author: Lu P
Year: 2006
Journal: Development
Title: Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function.
Volume: 133
Issue: 1
Pages: 33-42
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GXD Expression
GXD Expression
Probe: MGI:17265
Assay Type: RNA in situ
Annotation Date: 2018-04-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677917
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6149011
Age: embryonic day 10.5
Image: 2F
Note: Authors report ectopic Fgf4 expression
Specimen Label: 2F
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:17265
Assay Type: RNA in situ
Annotation Date: 2018-04-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677917
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6149011
Age: embryonic day 10.5
Image: 2H
Note: Authors report ectopic Fgf4 expression
Specimen Label: 2H
Detected: true
Specimen Num: 10
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Publication
22954964 | J:190545
First Author: Boulet AM
Year: 2012
Journal: Dev Biol
Title: Signaling by FGF4 and FGF8 is required for axial elongation of the mouse embryo.
Volume: 371
Issue: 2
Pages: 235-45
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Publication
8663044 | -
First Author: Ornitz DM
Year: 1996
Journal: J Biol Chem
Title: Receptor specificity of the fibroblast growth factor family.
Volume: 271
Issue: 25
Pages: 15292-7
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Protein
P11403
Organism: Mus musculus/domesticus
Length: 202  
Fragment?: false
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Protein
A0A140LIV6
Organism: Mus musculus/domesticus
Length: 52  
Fragment?: true
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Protein
A0A7U3JW80
Organism: Mus musculus/domesticus
Length: 202  
Fragment?: false
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Publication
2549857 | -
 
First Author: Burgess WH
Year: 1989
Journal: Annu Rev Biochem
Title: The heparin-binding (fibroblast) growth factor family of proteins.
Volume: 58
Pages: 575-606
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Publication
7583099 | -
First Author: Wilkie AO
Year: 1995
Journal: Curr Biol
Title: Functions of fibroblast growth factors and their receptors.
Volume: 5
Issue: 5
Pages: 500-7
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Publication
3072709 | -
First Author: Thomas KA
Year: 1988
Journal: Trends Biochem Sci
Title: Transforming potential of fibroblast growth factor genes.
Volume: 13
Issue: 9
Pages: 327-8
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Publication
11276432 | J:67832
First Author: Ornitz DM
Year: 2001
Journal: Genome Biol
Title: Fibroblast growth factors.
Volume: 2
Issue: 3
Pages: REVIEWS3005
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Publication
10830168 | -
First Author: Plotnikov AN
Year: 2000
Journal: Cell
Title: Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity.
Volume: 101
Issue: 4
Pages: 413-24
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Publication
8652550 | -
First Author: Blaber M
Year: 1996
Journal: Biochemistry
Title: X-ray crystal structure of human acidic fibroblast growth factor.
Volume: 35
Issue: 7
Pages: 2086-94
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Publication
1705486 | -
First Author: Vlodavsky I
Year: 1990
Journal: Cancer Metastasis Rev
Title: Extracellular matrix-resident growth factors and enzymes: possible involvement in tumor metastasis and angiogenesis.
Volume: 9
Issue: 3
Pages: 203-26
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Publication
8760337 | -
First Author: Green PJ
Year: 1996
Journal: Bioessays
Title: Promiscuity of fibroblast growth factor receptors.
Volume: 18
Issue: 8
Pages: 639-46
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Publication
23000357 | -
First Author: Yardley N
Year: 2012
Journal: Dev Biol
Title: FGF signaling transforms non-neural ectoderm into neural crest.
Volume: 372
Issue: 2
Pages: 166-77
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Publication
15689573 | -
First Author: Böttcher RT
Year: 2005
Journal: Endocr Rev
Title: Fibroblast growth factor signaling during early vertebrate development.
Volume: 26
Issue: 1
Pages: 63-77
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Publication
10441498 | J:56785
First Author: Koga C
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Characterization of a novel member of the FGF family, XFGF-20, in Xenopus laevis.
Volume: 261
Issue: 3
Pages: 756-65
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Publication
23108135 | -
First Author: Nakamizo S
Year: 2013
Journal: Skin Pharmacol Physiol
Title: Topical treatment with basic fibroblast growth factor promotes wound healing and barrier recovery induced by skin abrasion.
Volume: 26
Issue: 1
Pages: 22-9
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Publication
23016864 | -
First Author: Kumar SB
Year: 2013
Journal: Curr Pharm Des
Title: Fibroblast growth factor receptor inhibitors.
Volume: 19
Issue: 4
Pages: 687-701
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Publication
1649700 | -
First Author: Amaya E
Year: 1991
Journal: Cell
Title: Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos.
Volume: 66
Issue: 2
Pages: 257-70
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Publication
11746231 | -
First Author: Borland CZ
Year: 2001
Journal: Bioessays
Title: Fibroblast growth factor signaling in Caenorhabditis elegans.
Volume: 23
Issue: 12
Pages: 1120-30
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Publication
14745970 | -
First Author: Coumoul X
Year: 2003
Journal: Birth Defects Res C Embryo Today
Title: Roles of FGF receptors in mammalian development and congenital diseases.
Volume: 69
Issue: 4
Pages: 286-304
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Publication
8978613 | -
First Author: Sutherland D
Year: 1996
Journal: Cell
Title: branchless encodes a Drosophila FGF homolog that controls tracheal cell migration and the pattern of branching.
Volume: 87
Issue: 6
Pages: 1091-101
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Publication
8001146 | -
First Author: Laufer E
Year: 1994
Journal: Cell
Title: Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud.
Volume: 79
Issue: 6
Pages: 993-1003
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GXD Expression
GXD Expression
     
Probe: MGI:6172883
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190270
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Fgf4
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6172883
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190270
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Fgf4
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6172883
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6190270
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Fgf4
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6172883
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190270
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Fgf4
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6172883
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190270
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Fgf4
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6172883
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190270
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Fgf4
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6172883
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190270
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Fgf4
Detected: false
Specimen Num: 7
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Publication
24063807 | J:203997
First Author: Krawchuk D
Year: 2013
Journal: Dev Biol
Title: FGF4 is a limiting factor controlling the proportions of primitive endoderm and epiblast in the ICM of the mouse blastocyst.
Volume: 384
Issue: 1
Pages: 65-71
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Publication
10985858 | J:64867
First Author: Fraidenraich D
Year: 2000
Journal: Dev Biol
Title: Activation of fgf4 gene expression in the myotomes is regulated by myogenic bHLH factors and by sonic hedgehog.
Volume: 225
Issue: 2
Pages: 392-406
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Publication
23193166 | J:191065
First Author: Kang M
Year: 2013
Journal: Development
Title: FGF4 is required for lineage restriction and salt-and-pepper distribution of primitive endoderm factors but not their initial expression in the mouse.
Volume: 140
Issue: 2
Pages: 267-79
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Publication
28806497 | J:252458
First Author: Hamidi K
Year: 2017
Journal: Anat Rec (Hoboken)
Title: Tooth Morphogenesis and FGF4 Expression During Development of Molar Tooth in Three Muroid Rodents: Calomyscus elburzensis (Calomyscidae), Mesocricetus auratus (Cricetidae) and Mus musculus (Muridae).
Volume: 300
Issue: 12
Pages: 2138-2149
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Publication
15183731 | J:92206
First Author: Iwahori A
Year: 2004
Journal: Dev Biol
Title: A conserved enhancer element that drives FGF4 gene expression in the embryonic myotomes is synergistically activated by GATA and bHLH proteins.
Volume: 270
Issue: 2
Pages: 525-37
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GXD Expression
GXD Expression
Probe: MGI:1310046
Assay Type: RNA in situ
Annotation Date: 1998-11-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:1310051
Age: embryonic day 10.5
Image: 2A
Note: Fgf4 was expressed in a posterior AER domain.
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:17265
Assay Type: RNA in situ
Annotation Date: 2018-04-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1640617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6149011
Age: embryonic day 10.5
Image: 2C
Note: Low levels of Fgf4 in posterior part of limb bud.
Specimen Label: 2C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:17265
Assay Type: RNA in situ
Annotation Date: 2018-04-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1640617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6149011
Age: embryonic day 10.5
Image: 2C'
Note: Low levels of Fgf4 in posterior part of limb bud.
Specimen Label: 2C'
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:17265
Assay Type: RNA in situ
Annotation Date: 2018-04-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689217
Pattern: Widespread
Stage: TS17
Assay Id: MGI:6149011
Age: embryonic day 10.5
Image: 2F
Note: Fgf4 expression extended throughout the apical ectodermal ridge.
Specimen Label: 2F
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:1330983
Assay Type: RNA in situ
Annotation Date: 1999-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1725119
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331127
Age: embryonic day 11.5
Image: 3A
Note: Fgf4 expression is detected in the posterior AER.
Specimen Label: 3A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:1330983
Assay Type: RNA in situ
Annotation Date: 1999-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1724719
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331127
Age: embryonic day 11.5
Image: 3A
Note: Fgf4 expression is detected in the posterior AER.
Specimen Label: 3A
Detected: true
Specimen Num: 1
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Publication
37471320 | J:338267
First Author: Goissis MD
Year: 2023
Journal: PLoS One
Title: Influence of FGF4 and BMP4 on FGFR2 dynamics during the segregation of epiblast and primitive endoderm cells in the pre-implantation mouse embryo.
Volume: 18
Issue: 7
Pages: e0279515
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Publication
11180951 | J:67731
First Author: Revest JM
Year: 2001
Journal: Dev Biol
Title: Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 and is required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1, or Bmp4.
Volume: 231
Issue: 1
Pages: 47-62
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GXD Expression
GXD Expression
Probe: MGI:17265
Assay Type: RNA in situ
Annotation Date: 2018-04-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6149011
Age: embryonic day 10.5
Image: 2B
Note: Authors report ectopic expression of Fgf4 in the anterior part of the apical ectodermal ridge.
Specimen Label: 2B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:17265
Assay Type: RNA in situ
Annotation Date: 2018-04-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1640617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6149011
Age: embryonic day 10.5
Image: 2D'
Note: Expression reduced posteriorly in limb bud. Authors report ectopic anterior spot of Fgf4 expression.
Specimen Label: 2D'
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:1330983
Assay Type: RNA in situ
Annotation Date: 1999-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1725119
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331127
Age: embryonic day 11.5
Image: 3B
Note: Fgf4 was ectopically expressed in the anterior AER of both fore- and hindlimb buds.
Specimen Label: 3B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1330983
Assay Type: RNA in situ
Annotation Date: 1999-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1724719
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331127
Age: embryonic day 11.5
Image: 3B
Note: Fgf4 was ectopically expressed in the anterior AER of both fore- and hindlimb buds.
Specimen Label: 3B
Detected: true
Specimen Num: 2
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Publication
33210601 | J:313582
   
First Author: Anderson MJ
Year: 2020
Journal: Elife
Title: Fgf4 maintains Hes7 levels critical for normal somite segmentation clock function.
Volume: 9
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GXD Expression
GXD Expression
Probe: MGI:6281183
Assay Type: RNA in situ
Annotation Date: 2019-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160414
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6281420
Age: embryonic day 3.5
Image: 5A +/-
Note: Expressed in early epiblast progenitors. The proportions of cells expressing Fgf4 were significantly higher compared with wild type.
Specimen Label: 5A +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6281183
Assay Type: RNA in situ
Annotation Date: 2019-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Pattern: Not Specified
Stage: TS05
Assay Id: MGI:6281420
Age: embryonic day 3.75
Note: Expressed in early epiblast progenitors. The proportions of cells expressing Fgf4 were significantly higher compared with wild type.
Specimen Label: not shown
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:6281183
Assay Type: RNA in situ
Annotation Date: 2019-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160414
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6281420
Age: embryonic day 3.25
Note: Expressed in early epiblast progenitors. The proportions of cells expressing Fgf4 were significantly higher compared with wild type. A precocious induction of epiblast cells was shown.
Specimen Label: not shown
Detected: true
Specimen Num: 4
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Publication
26666435 | J:229949
First Author: Anderson MJ
Year: 2016
Journal: Genesis
Title: Fgf3-Fgf4-cis: A new mouse line for studying Fgf functions during mouse development.
Volume: 54
Issue: 2
Pages: 91-8
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•
•
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Publication
7809630 | J:22275
First Author: Feldman B
Year: 1995
Journal: Science
Title: Requirement of FGF-4 for postimplantation mouse development.
Volume: 267
Issue: 5195
Pages: 246-9
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•
•
•
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Publication
11146552 | J:66389
First Author: Morini M
Year: 2000
Journal: Oncogene
Title: Hyperplasia and impaired involution in the mammary gland of transgenic mice expressing human FGF4.
Volume: 19
Issue: 52
Pages: 6007-14
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Publication
24082130 | J:201993
First Author: Melidoni AN
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Selecting antagonistic antibodies that control differentiation through inducible expression in embryonic stem cells.
Volume: 110
Issue: 44
Pages: 17802-7
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•
•
•
Publication
24292013 | J:208289
First Author: Ohnishi Y
Year: 2014
Journal: Nat Cell Biol
Title: Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages.
Volume: 16
Issue: 1
Pages: 27-37
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Publication
9626498 | J:47965
First Author: Carlton MB
Year: 1998
Journal: Dev Dyn
Title: Crouzon-like craniofacial dysmorphology in the mouse is caused by an insertional mutation at the Fgf3/Fgf4 locus.
Volume: 212
Issue: 2
Pages: 242-9
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Publication
19384958 | J:148406
First Author: Eloy-Trinquet S
Year: 2009
Journal: Dev Dyn
Title: Fgf signaling components are associated with muscles and tendons during limb development.
Volume: 238
Issue: 5
Pages: 1195-206
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Publication
15505202 | J:93446
First Author: Guzman-Ayala M
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment.
Volume: 101
Issue: 44
Pages: 15656-60
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Publication
31320324 | J:293567
 
First Author: Azami T
Year: 2019
Journal: Development
Title: Regulation of the ERK signalling pathway in the developing mouse blastocyst.
Volume: 146
Issue: 14
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Publication
21839920 | J:176064
First Author: Shimokawa K
Year: 2011
Journal: Dev Cell
Title: Cell surface heparan sulfate chains regulate local reception of FGF signaling in the mouse embryo.
Volume: 21
Issue: 2
Pages: 257-72
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Publication
18265010 | J:132122
First Author: Delgado I
Year: 2008
Journal: Dev Dyn
Title: The incomplete inactivation of Fgf8 in the limb ectoderm affects the morphogenesis of the anterior autopod through BMP-mediated cell death.
Volume: 237
Issue: 3
Pages: 649-58
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Publication
10725233 | J:60985
First Author: Wells JM
Year: 2000
Journal: Development
Title: Early mouse endoderm is patterned by soluble factors from adjacent germ layers.
Volume: 127
Issue: 8
Pages: 1563-72
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Publication
10669750 | J:64686
First Author: Kobayashi A
Year: 2000
Journal: Mol Cell Biol
Title: A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/POZ domain.
Volume: 20
Issue: 5
Pages: 1733-46
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Publication
24912677 | J:224277
First Author: Han A
Year: 2014
Journal: Mol Cell Biol
Title: ALK5-mediated transforming growth factor β signaling in neural crest cells controls craniofacial muscle development via tissue-tissue interactions.
Volume: 34
Issue: 16
Pages: 3120-31
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Publication
32561646 | J:291438
First Author: Guzzetta A
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation.
Volume: 117
Issue: 27
Pages: 15712-15723
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Publication
12701101 | J:83305
First Author: Zhang Q
Year: 2003
Journal: Dev Dyn
Title: Loss of the Tg737 protein results in skeletal patterning defects.
Volume: 227
Issue: 1
Pages: 78-90
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Publication
12175489 | J:76826
First Author: Zuniga A
Year: 2002
Journal: Mech Dev
Title: Mouse Twist is required for fibroblast growth factor-mediated epithelial-mesenchymal signalling and cell survival during limb morphogenesis.
Volume: 114
Issue: 1-2
Pages: 51-9
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Publication
12152071 | J:78402
First Author: Sun X
Year: 2002
Journal: Nature
Title: Functions of FGF signalling from the apical ectodermal ridge in limb development.
Volume: 418
Issue: 6897
Pages: 501-8
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Publication
12514105 | J:81180
First Author: Avilion AA
Year: 2003
Journal: Genes Dev
Title: Multipotent cell lineages in early mouse development depend on SOX2 function.
Volume: 17
Issue: 1
Pages: 126-40
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Publication
17309607 | J:121913
First Author: Cho SW
Year: 2007
Journal: Differentiation
Title: The primary enamel knot determines the position of the first buccal cusp in developing mice molars.
Volume: 75
Issue: 5
Pages: 441-51
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Publication
10662638 | J:60091
First Author: Moon AM
Year: 2000
Journal: Development
Title: Normal limb development in conditional mutants of Fgf4.
Volume: 127
Issue: 5
Pages: 989-96
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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