| Type | 
            Details | 
            Score | 
          
          
              | Gene | 
              
                  
              
              
                |  Type: | 
                    gene | 
                     
              
                |  Organism: | 
                    human | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Gene | 
              
                  
              
              
                |  Type: | 
                    gene | 
                     
              
                |  Organism: | 
                    frog, western clawed | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Gene | 
              
                  
              
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Gene | 
              
                  
              
              
                |  Type: | 
                    gene | 
                     
              
                |  Organism: | 
                    chimpanzee | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Gene | 
              
                  
              
              
                |  Type: | 
                    gene | 
                     
              
                |  Organism: | 
                    dog, domestic | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Gene | 
              
                  
              
              
                |  Type: | 
                    gene | 
                     
              
                |  Organism: | 
                    cattle | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Gene | 
              
                  
              
              
                |  Type: | 
                    gene | 
                     
              
                |  Organism: | 
                    chicken | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Gene | 
              
                  
              
              
                |  Type: | 
                    gene | 
                     
              
                |  Organism: | 
                    zebrafish | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Gene | 
              
                  
              
              
                |  Type: | 
                    gene | 
                     
              
                |  Organism: | 
                    macaque, rhesus | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Protein | 
              
                  
              
              
                |  Organism: | 
                    Mus musculus/domesticus | 
                     
              
                |  Length: | 
                     
  
  
    
  
    
     
    
        277
    
  
  
    
  
   | 
                   
              
                |  Fragment?: | 
                    false | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Protein Coding Gene | 
              
                  
              
              
                |  Type: | 
                    protein_coding_gene | 
                     
              
                |  Organism: | 
                    mouse, laboratory | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:5556218 | 
                     
              
                |  Assay Type: | 
                    Northern blot | 
                     
              
                |  Annotation Date: | 
                    2014-04-09 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Not Specified | 
                     
              
                |  Emaps: | 
                    EMAPS:1737323 | 
                     
              
                 | 
                    
                            
              
                |  Stage: | 
                    TS23 | 
                     
              
                |  Assay Id: | 
                    MGI:5556255 | 
                     
              
                |  Age: | 
                    embryonic day 15.5 | 
                     
              
                 | 
                    
                            
              
                 | 
                    
                            
              
                |  Specimen Label: | 
                    Fgfr2 | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    2 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Gong SG | 
                     
              
                |  Year: | 
                    2012 | 
                     
              
                |  Journal: | 
                    Childs Nerv Syst | 
                     
              
                |  Title: | 
                    The Fgfr2 W290R mouse model of Crouzon syndrome. | 
                     
              
                |  Volume: | 
                    28 | 
                     
              
                |  Issue: | 
                    9 | 
                     
              
                |  Pages: | 
                    1495-503 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:3639883 | 
                     
              
                |  Assay Type: | 
                    RNA in situ | 
                     
              
                |  Annotation Date: | 
                    2006-08-04 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Not Specified | 
                     
              
                |  Emaps: | 
                    EMAPS:1755022 | 
                     
              
                |  Pattern: | 
                    Regionally restricted | 
                     
              
                |  Stage: | 
                    TS22 | 
                     
              
                |  Assay Id: | 
                    MGI:3639929 | 
                     
              
                |  Age: | 
                    embryonic day 14.5 | 
                     
              
                 | 
                    
                            
              
                |  Note: | 
                    Expression was detected in the inferior olivary nucleus. | 
                     
              
                |  Specimen Label: | 
                    6P Fgfr2 | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    1 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:3639883 | 
                     
              
                |  Assay Type: | 
                    RNA in situ | 
                     
              
                |  Annotation Date: | 
                    2006-08-04 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Not Specified | 
                     
              
                |  Emaps: | 
                    EMAPS:1755022 | 
                     
              
                |  Pattern: | 
                    Regionally restricted | 
                     
              
                |  Stage: | 
                    TS22 | 
                     
              
                |  Assay Id: | 
                    MGI:3639929 | 
                     
              
                |  Age: | 
                    embryonic day 14.5 | 
                     
              
                 | 
                    
                            
              
                |  Note: | 
                    Expression was detected in the inferior olivary nucleus (ION) as in wild type, but the ION area was increased in the mutant. | 
                     
              
                |  Specimen Label: | 
                    6P Fgfr2 | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    2 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Warzecha CC | 
                     
              
                |  Year: | 
                    2009 | 
                     
              
                |  Journal: | 
                    Mol Cell | 
                     
              
                |  Title: | 
                    ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. | 
                     
              
                |  Volume: | 
                    33 | 
                     
              
                |  Issue: | 
                    5 | 
                     
              
                |  Pages: | 
                    591-601 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Mai S | 
                     
              
                |  Year: | 
                    2010 | 
                     
              
                |  Journal: | 
                    Dev Dyn | 
                     
              
                |  Title: | 
                    The missense mutation W290R in Fgfr2 causes developmental defects from aberrant IIIb and IIIc signaling. | 
                     
              
                |  Volume: | 
                    239 | 
                     
              
                |  Issue: | 
                    6 | 
                     
              
                |  Pages: | 
                    1888-900 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Wang Y | 
                     
              
                |  Year: | 
                    2012 | 
                     
              
                |  Journal: | 
                    J Clin Invest | 
                     
              
                |  Title: | 
                    p38 Inhibition ameliorates skin and skull abnormalities in Fgfr2 Beare-Stevenson mice. | 
                     
              
                |  Volume: | 
                    122 | 
                     
              
                |  Issue: | 
                    6 | 
                     
              
                |  Pages: | 
                    2153-64 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Leng S | 
                     
              
                |  Year: | 
                    2020 | 
                     
              
                |  Journal: | 
                    Nat Commun | 
                     
              
                |  Title: | 
                    β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis. | 
                     
              
                |  Volume: | 
                    11 | 
                     
              
                |  Issue: | 
                    1 | 
                     
              
                |  Pages: | 
                    1680 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Rigueur D | 
                     
              
                |  Year: | 
                    2019 | 
                     
              
                |  Journal: | 
                    Genesis | 
                     
              
                |  Title: | 
                    A requirement for Fgfr2 in middle ear development. | 
                     
              
                |  Volume: | 
                    57 | 
                     
              
                |  Issue: | 
                    1 | 
                     
              
                |  Pages: | 
                    e23252 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Sims-Lucas S | 
                     
              
                |  Year: | 
                    2011 | 
                     
              
                |  Journal: | 
                    Development | 
                     
              
                |  Title: | 
                    Independent roles of Fgfr2 and Frs2alpha in ureteric epithelium. | 
                     
              
                |  Volume: | 
                    138 | 
                     
              
                |  Issue: | 
                    7 | 
                     
              
                |  Pages: | 
                    1275-80 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Aldridge K | 
                     
              
                |  Year: | 
                    2010 | 
                     
              
                |  Journal: | 
                    Dev Dyn | 
                     
              
                |  Title: | 
                    Brain phenotypes in two FGFR2 mouse models for Apert syndrome. | 
                     
              
                |  Volume: | 
                    239 | 
                     
              
                |  Issue: | 
                    3 | 
                     
              
                |  Pages: | 
                    987-97 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Zingg D | 
                     
              
                |  Year: | 
                    2022 | 
                     
              
                |  Journal: | 
                    Nature | 
                     
              
                |  Title: | 
                    Truncated FGFR2 is a clinically actionable oncogene in multiple cancers. | 
                     
              
                |  Volume: | 
                    608 | 
                     
              
                |  Issue: | 
                    7923 | 
                     
              
                |  Pages: | 
                    609-617 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Guasti L | 
                     
              
                |  Year: | 
                    2013 | 
                     
              
                |  Journal: | 
                    Mol Cell Endocrinol | 
                     
              
                |  Title: | 
                    FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development. | 
                     
              
                |  Volume: | 
                    371 | 
                     
              
                |  Issue: | 
                    1-2 | 
                     
              
                |  Pages: | 
                    182-8 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Hosokawa R | 
                     
              
                |  Year: | 
                    2009 | 
                     
              
                |  Journal: | 
                    J Exp Zool B Mol Dev Evol | 
                     
              
                |  Title: | 
                    Epithelial-specific requirement of FGFR2 signaling during tooth and palate development. | 
                     
              
                |  Volume: | 
                    312B | 
                     
              
                |  Issue: | 
                    4 | 
                     
              
                |  Pages: | 
                    343-50 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Kim S | 
                     
              
                |  Year: | 
                    2013 | 
                     
              
                |  Journal: | 
                    PLoS One | 
                     
              
                |  Title: | 
                    FGFR2 promotes breast tumorigenicity through maintenance of breast tumor-initiating cells. | 
                     
              
                |  Volume: | 
                    8 | 
                     
              
                |  Issue: | 
                    1 | 
                     
              
                |  Pages: | 
                    e51671 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Chan KM | 
                     
              
                |  Year: | 
                    2012 | 
                     
              
                |  Journal: | 
                    Dev Cell | 
                     
              
                |  Title: | 
                    MT1-MMP inactivates ADAM9 to regulate FGFR2 signaling and calvarial osteogenesis. | 
                     
              
                |  Volume: | 
                    22 | 
                     
              
                |  Issue: | 
                    6 | 
                     
              
                |  Pages: | 
                    1176-90 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Gredler ML | 
                     
              
                |  Year: | 
                    2015 | 
                     
              
                |  Journal: | 
                    Development | 
                     
              
                |  Title: | 
                    Tissue-specific roles of Fgfr2 in development of the external genitalia. | 
                     
              
                |  Volume: | 
                    142 | 
                     
              
                |  Issue: | 
                    12 | 
                     
              
                |  Pages: | 
                    2203-12 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Bagheri-Fam S | 
                     
              
                |  Year: | 
                    2008 | 
                     
              
                |  Journal: | 
                    Dev Biol | 
                     
              
                |  Title: | 
                    Loss of Fgfr2 leads to partial XY sex reversal. | 
                     
              
                |  Volume: | 
                    314 | 
                     
              
                |  Issue: | 
                    1 | 
                     
              
                |  Pages: | 
                    71-83 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Bagheri-Fam S | 
                     
              
                |  Year: | 
                    2017 | 
                     
              
                |  Journal: | 
                    Endocrinology | 
                     
              
                |  Title: | 
                    Testis Determination Requires a Specific FGFR2 Isoform to Repress FOXL2. | 
                     
              
                |  Volume: | 
                    158 | 
                     
              
                |  Issue: | 
                    11 | 
                     
              
                |  Pages: | 
                    3832-3843 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Ikeda Y | 
                     
              
                |  Year: | 
                    2017 | 
                     
              
                |  Journal: | 
                    Am J Physiol Renal Physiol | 
                     
              
                |  Title: | 
                    Fgfr2 is integral for bladder mesenchyme patterning and function. | 
                     
              
                |  Volume: | 
                    312 | 
                     
              
                |  Issue: | 
                    4 | 
                     
              
                |  Pages: | 
                    F607-F618 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Bagheri-Fam S | 
                     
              
                |  Year: | 
                    2015 | 
                     
              
                |  Journal: | 
                    Hum Mol Genet | 
                     
              
                |  Title: | 
                    FGFR2 mutation in 46,XY sex reversal with craniosynostosis. | 
                     
              
                |  Volume: | 
                    24 | 
                     
              
                |  Issue: | 
                    23 | 
                     
              
                |  Pages: | 
                    6699-710 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Balasooriya GI | 
                     
              
                |  Year: | 
                    2017 | 
                     
              
                |  Journal: | 
                    Development | 
                     
              
                |  Title: | 
                    FGFR2 is required for airway basal cell self-renewal and terminal differentiation. | 
                     
              
                |  Volume: | 
                    144 | 
                     
              
                |  Issue: | 
                    9 | 
                     
              
                |  Pages: | 
                    1600-1606 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6386982 | 
                     
              
                |  Assay Type: | 
                    RNase protection | 
                     
              
                |  Annotation Date: | 
                    2020-01-30 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Not Specified | 
                     
              
                |  Emaps: | 
                    EMAPS:1783828 | 
                     
              
                 | 
                    
                            
              
                |  Stage: | 
                    TS28 | 
                     
              
                |  Assay Id: | 
                    MGI:6386999 | 
                     
              
                |  Age: | 
                    postnatal adult | 
                     
              
                |  Image: | 
                    S2 | 
                     
              
                 | 
                    
                            
              
                |  Specimen Label: | 
                    Fgfr2 flox/flox +CRE | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    2 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6386982 | 
                     
              
                |  Assay Type: | 
                    RNase protection | 
                     
              
                |  Annotation Date: | 
                    2020-01-30 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Not Specified | 
                     
              
                |  Emaps: | 
                    EMAPS:1783828 | 
                     
              
                 | 
                    
                            
              
                |  Stage: | 
                    TS28 | 
                     
              
                |  Assay Id: | 
                    MGI:6386999 | 
                     
              
                |  Age: | 
                    postnatal adult | 
                     
              
                |  Image: | 
                    S2 | 
                     
              
                 | 
                    
                            
              
                |  Specimen Label: | 
                    FgfR2 +/+ +CRE | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    4 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6451697 | 
                     
              
                |  Assay Type: | 
                    Immunohistochemistry | 
                     
              
                |  Annotation Date: | 
                    2020-08-26 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Not Specified | 
                     
              
                |  Emaps: | 
                    EMAPS:3286620 | 
                     
              
                |  Pattern: | 
                    Not Specified | 
                     
              
                |  Stage: | 
                    TS20 | 
                     
              
                |  Assay Id: | 
                    MGI:6451702 | 
                     
              
                |  Age: | 
                    embryonic day 12.5 | 
                     
              
                 | 
                    
                            
              
                 | 
                    
                            
              
                |  Specimen Label: | 
                    S1 FGFR2 E12.5 | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    1 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6451697 | 
                     
              
                |  Assay Type: | 
                    Immunohistochemistry | 
                     
              
                |  Annotation Date: | 
                    2020-08-26 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Not Specified | 
                     
              
                |  Emaps: | 
                    EMAPS:3286621 | 
                     
              
                |  Pattern: | 
                    Not Specified | 
                     
              
                |  Stage: | 
                    TS21 | 
                     
              
                |  Assay Id: | 
                    MGI:6451702 | 
                     
              
                |  Age: | 
                    embryonic day 13.5 | 
                     
              
                 | 
                    
                            
              
                 | 
                    
                            
              
                |  Specimen Label: | 
                    S1 FGFR2 E13.5 | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    2 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6451697 | 
                     
              
                |  Assay Type: | 
                    Immunohistochemistry | 
                     
              
                |  Annotation Date: | 
                    2020-08-26 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Not Specified | 
                     
              
                |  Emaps: | 
                    EMAPS:3286020 | 
                     
              
                |  Pattern: | 
                    Regionally restricted | 
                     
              
                |  Stage: | 
                    TS20 | 
                     
              
                |  Assay Id: | 
                    MGI:6451702 | 
                     
              
                |  Age: | 
                    embryonic day 12.5 | 
                     
              
                 | 
                    
                            
              
                |  Note: | 
                    Expression on basal surface of distal airway epithelium. | 
                     
              
                |  Specimen Label: | 
                    S1 FGFR2 E12.5 | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    1 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6451697 | 
                     
              
                |  Assay Type: | 
                    Immunohistochemistry | 
                     
              
                |  Annotation Date: | 
                    2020-08-26 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Not Specified | 
                     
              
                |  Emaps: | 
                    EMAPS:3286021 | 
                     
              
                |  Pattern: | 
                    Regionally restricted | 
                     
              
                |  Stage: | 
                    TS21 | 
                     
              
                |  Assay Id: | 
                    MGI:6451702 | 
                     
              
                |  Age: | 
                    embryonic day 13.5 | 
                     
              
                 | 
                    
                            
              
                |  Note: | 
                    Expression on basal surface of distal airway epithelium. | 
                     
              
                |  Specimen Label: | 
                    S1 FGFR2 E13.5 | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    2 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6363656 | 
                     
              
                |  Assay Type: | 
                    RNA in situ | 
                     
              
                |  Annotation Date: | 
                    2019-10-16 | 
                     
              
                |  Strength: | 
                    Strong | 
                     
              
                |  Sex: | 
                    Not Specified | 
                     
              
                |  Emaps: | 
                    EMAPS:3522328 | 
                     
              
                |  Pattern: | 
                    Not Specified | 
                     
              
                |  Stage: | 
                    TS28 | 
                     
              
                |  Assay Id: | 
                    MGI:6363685 | 
                     
              
                |  Age: | 
                    postnatal adult | 
                     
              
                 | 
                    
                            
              
                 | 
                    
                            
              
                |  Specimen Label: | 
                    Fgfr2 lox/lox not shown | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    1 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6386982 | 
                     
              
                |  Assay Type: | 
                    RNase protection | 
                     
              
                |  Annotation Date: | 
                    2020-01-30 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Not Specified | 
                     
              
                |  Emaps: | 
                    EMAPS:1783828 | 
                     
              
                 | 
                    
                            
              
                |  Stage: | 
                    TS28 | 
                     
              
                |  Assay Id: | 
                    MGI:6386999 | 
                     
              
                |  Age: | 
                    postnatal adult | 
                     
              
                |  Image: | 
                    S2 | 
                     
              
                 | 
                    
                            
              
                |  Specimen Label: | 
                    FgfR2 flox/+ +CRE | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    3 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Arman E | 
                     
              
                |  Year: | 
                    1999 | 
                     
              
                |  Journal: | 
                    Proc Natl Acad Sci U S A | 
                     
              
                |  Title: | 
                    Fgfr2 is required for limb outgrowth and lung-branching morphogenesis. | 
                     
              
                |  Volume: | 
                    96 | 
                     
              
                |  Issue: | 
                    21 | 
                     
              
                |  Pages: | 
                    11895-9 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Molotkov A | 
                     
              
                |  Year: | 
                    2017 | 
                     
              
                |  Journal: | 
                    Dev Cell | 
                     
              
                |  Title: | 
                    Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency. | 
                     
              
                |  Volume: | 
                    41 | 
                     
              
                |  Issue: | 
                    5 | 
                     
              
                |  Pages: | 
                    511-526.e4 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Clark JF | 
                     
              
                |  Year: | 
                    2023 | 
                     
              
                |  Journal: | 
                    Biol Open | 
                     
              
                |  Title: | 
                    FRS2-independent GRB2 interaction with FGFR2 is not required for embryonic development. | 
                     
              
                |  Volume: | 
                    12 | 
                     
              
                |  Issue: | 
                    7 | 
                     
              
                 | 
                    
                            
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Haffner-Krausz R | 
                     
              
                |  Year: | 
                    1999 | 
                     
              
                |  Journal: | 
                    Mech Dev | 
                     
              
                |  Title: | 
                    Expression of Fgfr2 in the early mouse embryo indicates its involvement in preimplantation development. | 
                     
              
                |  Volume: | 
                    85 | 
                     
              
                |  Issue: | 
                    1-2 | 
                     
              
                |  Pages: | 
                    167-72 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Coumoul X | 
                     
              
                |  Year: | 
                    2005 | 
                     
              
                |  Journal: | 
                    Nucleic Acids Res | 
                     
              
                |  Title: | 
                    Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference. | 
                     
              
                |  Volume: | 
                    33 | 
                     
              
                |  Issue: | 
                    11 | 
                     
              
                |  Pages: | 
                    e102 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Bird AD | 
                     
              
                |  Year: | 
                    2023 | 
                     
              
                |  Journal: | 
                    Endocrinology | 
                     
              
                |  Title: | 
                    Somatic FGFR2 is Required for Germ Cell Maintenance in the Mouse Ovary. | 
                     
              
                |  Volume: | 
                    164 | 
                     
              
                |  Issue: | 
                    5 | 
                     
              
                 | 
                    
                            
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Eswarakumar VP | 
                     
              
                |  Year: | 
                    2002 | 
                     
              
                |  Journal: | 
                    Development | 
                     
              
                |  Title: | 
                    The IIIc alternative of Fgfr2 is a positive regulator of bone formation. | 
                     
              
                |  Volume: | 
                    129 | 
                     
              
                |  Issue: | 
                    16 | 
                     
              
                |  Pages: | 
                    3783-93 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Häfner R | 
                     
              
                |  Year: | 
                    2015 | 
                     
              
                |  Journal: | 
                    Mol Cell Endocrinol | 
                     
              
                |  Title: | 
                    Fgfr2 is required for the expansion of the early adrenocortical primordium. | 
                     
              
                |  Volume: | 
                    413 | 
                     
              
                 | 
                    
                            
              
                |  Pages: | 
                    168-77 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Schmahl J | 
                     
              
                |  Year: | 
                    2004 | 
                     
              
                |  Journal: | 
                    Development | 
                     
              
                |  Title: | 
                    Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination. | 
                     
              
                |  Volume: | 
                    131 | 
                     
              
                |  Issue: | 
                    15 | 
                     
              
                |  Pages: | 
                    3627-36 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Meuser M | 
                     
              
                |  Year: | 
                    2022 | 
                     
              
                |  Journal: | 
                    Development | 
                     
              
                |  Title: | 
                    FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. | 
                     
              
                |  Volume: | 
                    149 | 
                     
              
                |  Issue: | 
                    1 | 
                     
              
                 | 
                    
                            
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Morita J | 
                     
              
                |  Year: | 
                    2014 | 
                     
              
                |  Journal: | 
                    Dev Dyn | 
                     
              
                |  Title: | 
                    Soluble form of FGFR2 with S252W partially prevents craniosynostosis of the apert mouse model. | 
                     
              
                |  Volume: | 
                    243 | 
                     
              
                |  Issue: | 
                    4 | 
                     
              
                |  Pages: | 
                    560-7 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Yokota M | 
                     
              
                |  Year: | 
                    2014 | 
                     
              
                |  Journal: | 
                    PLoS One | 
                     
              
                |  Title: | 
                    Therapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis. | 
                     
              
                |  Volume: | 
                    9 | 
                     
              
                |  Issue: | 
                    7 | 
                     
              
                |  Pages: | 
                    e101693 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Xu W | 
                     
              
                |  Year: | 
                    2017 | 
                     
              
                |  Journal: | 
                    J Bone Miner Res | 
                     
              
                |  Title: | 
                    Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation. | 
                     
              
                |  Volume: | 
                    32 | 
                     
              
                |  Issue: | 
                    11 | 
                     
              
                |  Pages: | 
                    2194-2206 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Suzuki H | 
                     
              
                |  Year: | 
                    2012 | 
                     
              
                |  Journal: | 
                    J Cell Physiol | 
                     
              
                |  Title: | 
                    Apert syndrome mutant FGFR2 and its soluble form reciprocally alter osteogenesis of primary calvarial osteoblasts. | 
                     
              
                |  Volume: | 
                    227 | 
                     
              
                |  Issue: | 
                    9 | 
                     
              
                |  Pages: | 
                    3267-77 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Thakur M | 
                     
              
                |  Year: | 
                    2024 | 
                     
              
                |  Journal: | 
                    J Invest Dermatol | 
                     
              
                |  Title: | 
                    Inducible Keratinocyte Specific FGFR2 Deficiency Inhibits UVB-Induced Signaling, Proliferation, Inflammation, and Skin Carcinogenesis. | 
                     
              
                |  Volume: | 
                    144 | 
                     
              
                |  Issue: | 
                    2 | 
                     
              
                |  Pages: | 
                    341-350.e7 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Motch Perrine SM | 
                     
              
                |  Year: | 
                    2014 | 
                     
              
                |  Journal: | 
                    BMC Dev Biol | 
                     
              
                |  Title: | 
                    Craniofacial divergence by distinct prenatal growth patterns in Fgfr2 mutant mice. | 
                     
              
                |  Volume: | 
                    14 | 
                     
              
                 | 
                    
                            
              
                |  Pages: | 
                    8 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Yeh E | 
                     
              
                |  Year: | 
                    2013 | 
                     
              
                |  Journal: | 
                    PLoS One | 
                     
              
                |  Title: | 
                    Novel molecular pathways elicited by mutant FGFR2 may account for brain abnormalities in Apert syndrome. | 
                     
              
                |  Volume: | 
                    8 | 
                     
              
                |  Issue: | 
                    4 | 
                     
              
                |  Pages: | 
                    e60439 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Dorry SJ | 
                     
              
                |  Year: | 
                    2020 | 
                     
              
                |  Journal: | 
                    Am J Respir Cell Mol Biol | 
                     
              
                |  Title: | 
                    FGFR2 Is Required for AEC2 Homeostasis and Survival after Bleomycin-induced Lung Injury. | 
                     
              
                |  Volume: | 
                    62 | 
                     
              
                |  Issue: | 
                    5 | 
                     
              
                |  Pages: | 
                    608-621 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Aure MH | 
                     
              
                |  Year: | 
                    2023 | 
                     
              
                |  Journal: | 
                    Nat Commun | 
                     
              
                |  Title: | 
                    FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation. | 
                     
              
                |  Volume: | 
                    14 | 
                     
              
                |  Issue: | 
                    1 | 
                     
              
                |  Pages: | 
                    6485 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Hains DS | 
                     
              
                |  Year: | 
                    2010 | 
                     
              
                |  Journal: | 
                    J Urol | 
                     
              
                |  Title: | 
                    High incidence of vesicoureteral reflux in mice with Fgfr2 deletion in kidney mesenchyma. | 
                     
              
                |  Volume: | 
                    183 | 
                     
              
                |  Issue: | 
                    5 | 
                     
              
                |  Pages: | 
                    2077-84 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Iseki S | 
                     
              
                |  Year: | 
                    1999 | 
                     
              
                |  Journal: | 
                    Development | 
                     
              
                |  Title: | 
                    Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault. | 
                     
              
                |  Volume: | 
                    126 | 
                     
              
                |  Issue: | 
                    24 | 
                     
              
                |  Pages: | 
                    5611-20 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Siggers P | 
                     
              
                |  Year: | 
                    2014 | 
                     
              
                |  Journal: | 
                    PLoS One | 
                     
              
                |  Title: | 
                    A novel mouse Fgfr2 mutant, hobbyhorse (hob), exhibits complete XY gonadal sex reversal. | 
                     
              
                |  Volume: | 
                    9 | 
                     
              
                |  Issue: | 
                    6 | 
                     
              
                |  Pages: | 
                    e100447 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Müller Smith K | 
                     
              
                |  Year: | 
                    2012 | 
                     
              
                |  Journal: | 
                    Brain Res | 
                     
              
                |  Title: | 
                    Impaired motor coordination and disrupted cerebellar architecture in Fgfr1 and Fgfr2 double knockout mice. | 
                     
              
                |  Volume: | 
                    1460 | 
                     
              
                 | 
                    
                            
              
                |  Pages: | 
                    12-24 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Gorivodsky M | 
                     
              
                |  Year: | 
                    2003 | 
                     
              
                |  Journal: | 
                    Development | 
                     
              
                |  Title: | 
                    Novel roles of Fgfr2 in AER differentiation and positioning of the dorsoventral limb interface. | 
                     
              
                |  Volume: | 
                    130 | 
                     
              
                |  Issue: | 
                    22 | 
                     
              
                |  Pages: | 
                    5471-9 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Blak AA | 
                     
              
                |  Year: | 
                    2007 | 
                     
              
                |  Journal: | 
                    Dev Biol | 
                     
              
                |  Title: | 
                    Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain. | 
                     
              
                |  Volume: | 
                    303 | 
                     
              
                |  Issue: | 
                    1 | 
                     
              
                |  Pages: | 
                    231-43 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Candi E | 
                     
              
                |  Year: | 
                    2007 | 
                     
              
                |  Journal: | 
                    Proc Natl Acad Sci U S A | 
                     
              
                |  Title: | 
                    DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2. | 
                     
              
                |  Volume: | 
                    104 | 
                     
              
                |  Issue: | 
                    29 | 
                     
              
                |  Pages: | 
                    11999-2004 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Mukhopadhyay A | 
                     
              
                |  Year: | 
                    2013 | 
                     
              
                |  Journal: | 
                    Dev Biol | 
                     
              
                |  Title: | 
                    Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development. | 
                     
              
                |  Volume: | 
                    373 | 
                     
              
                |  Issue: | 
                    2 | 
                     
              
                |  Pages: | 
                    373-82 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Deuper L | 
                     
              
                |  Year: | 
                    2022 | 
                     
              
                |  Journal: | 
                    Development | 
                     
              
                |  Title: | 
                    Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. | 
                     
              
                |  Volume: | 
                    149 | 
                     
              
                |  Issue: | 
                    17 | 
                     
              
                 | 
                    
                            
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Wernlé KK | 
                     
              
                |  Year: | 
                    2023 | 
                     
              
                |  Journal: | 
                    Dev Dyn | 
                     
              
                |  Title: | 
                    Loss of Fgfr1 and Fgfr2 in Scleraxis-lineage cells leads to enlarged bone eminences and attachment cell death. | 
                     
              
                |  Volume: | 
                    252 | 
                     
              
                |  Issue: | 
                    9 | 
                     
              
                |  Pages: | 
                    1180-1188 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Iseki S | 
                     
              
                |  Year: | 
                    1997 | 
                     
              
                |  Journal: | 
                    Development | 
                     
              
                |  Title: | 
                    Fgfr2 and osteopontin domains in the developing skull vault are mutually exclusive and can be altered by locally applied FGF2. | 
                     
              
                |  Volume: | 
                    124 | 
                     
              
                |  Issue: | 
                    17 | 
                     
              
                |  Pages: | 
                    3375-84 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Kawane T | 
                     
              
                |  Year: | 
                    2018 | 
                     
              
                |  Journal: | 
                    Sci Rep | 
                     
              
                |  Title: | 
                    Runx2 is required for the proliferation of osteoblast progenitors and induces proliferation by regulating Fgfr2 and Fgfr3. | 
                     
              
                |  Volume: | 
                    8 | 
                     
              
                |  Issue: | 
                    1 | 
                     
              
                |  Pages: | 
                    13551 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Snyder-Warwick AK | 
                     
              
                |  Year: | 
                    2010 | 
                     
              
                |  Journal: | 
                    Proc Natl Acad Sci U S A | 
                     
              
                |  Title: | 
                    Analysis of a gain-of-function FGFR2 Crouzon mutation provides evidence of loss of function activity in the etiology of cleft palate. | 
                     
              
                |  Volume: | 
                    107 | 
                     
              
                |  Issue: | 
                    6 | 
                     
              
                |  Pages: | 
                    2515-20 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Stevens HE | 
                     
              
                |  Year: | 
                    2010 | 
                     
              
                |  Journal: | 
                    J Neurosci | 
                     
              
                |  Title: | 
                    Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits. | 
                     
              
                |  Volume: | 
                    30 | 
                     
              
                |  Issue: | 
                    16 | 
                     
              
                |  Pages: | 
                    5590-602 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Heuzé Y | 
                     
              
                |  Year: | 
                    2014 | 
                     
              
                |  Journal: | 
                    Bone | 
                     
              
                |  Title: | 
                    Morphological comparison of the craniofacial phenotypes of mouse models expressing the Apert FGFR2 S252W mutation in neural crest- or mesoderm-derived tissues. | 
                     
              
                |  Volume: | 
                    63 | 
                     
              
                 | 
                    
                            
              
                |  Pages: | 
                    101-9 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    De Langhe SP | 
                     
              
                |  Year: | 
                    2006 | 
                     
              
                |  Journal: | 
                    Dev Biol | 
                     
              
                |  Title: | 
                    Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung. | 
                     
              
                |  Volume: | 
                    299 | 
                     
              
                |  Issue: | 
                    1 | 
                     
              
                |  Pages: | 
                    52-62 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    MartÃnez-AbadÃas N | 
                     
              
                |  Year: | 
                    2010 | 
                     
              
                |  Journal: | 
                    Dev Dyn | 
                     
              
                |  Title: | 
                    Beyond the closed suture in apert syndrome mouse models: evidence of primary effects of FGFR2 signaling on facial shape at birth. | 
                     
              
                |  Volume: | 
                    239 | 
                     
              
                |  Issue: | 
                    11 | 
                     
              
                |  Pages: | 
                    3058-71 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6363656 | 
                     
              
                |  Assay Type: | 
                    RNA in situ | 
                     
              
                |  Annotation Date: | 
                    2019-10-16 | 
                     
              
                |  Strength: | 
                    Strong | 
                     
              
                |  Sex: | 
                    Not Specified | 
                     
              
                |  Emaps: | 
                    EMAPS:3522328 | 
                     
              
                |  Pattern: | 
                    Not Specified | 
                     
              
                |  Stage: | 
                    TS28 | 
                     
              
                |  Assay Id: | 
                    MGI:6363685 | 
                     
              
                |  Age: | 
                    postnatal adult | 
                     
              
                 | 
                    
                            
              
                |  Note: | 
                    Expression appeared normal compared to control. | 
                     
              
                |  Specimen Label: | 
                    En1 Cre/+ Fgfr2 lox/lox not shown | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    2 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6172900 | 
                     
              
                |  Assay Type: | 
                    RNA in situ | 
                     
              
                |  Annotation Date: | 
                    2018-07-25 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Not Specified | 
                     
              
                |  Emaps: | 
                    EMAPS:1689421 | 
                     
              
                |  Pattern: | 
                    Not Specified | 
                     
              
                |  Stage: | 
                    TS21 | 
                     
              
                |  Assay Id: | 
                    MGI:6190277 | 
                     
              
                |  Age: | 
                    embryonic day 13.5 | 
                     
              
                 | 
                    
                            
              
                 | 
                    
                            
              
                |  Specimen Label: | 
                    Table S2 - E13.5 - Fgfr2 | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    2 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6172900 | 
                     
              
                |  Assay Type: | 
                    RNA in situ | 
                     
              
                |  Annotation Date: | 
                    2018-07-25 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Male | 
                     
              
                |  Emaps: | 
                    EMAPS:1689424 | 
                     
              
                |  Pattern: | 
                    Not Specified | 
                     
              
                |  Stage: | 
                    TS24 | 
                     
              
                |  Assay Id: | 
                    MGI:6190277 | 
                     
              
                |  Age: | 
                    embryonic day 15.5 | 
                     
              
                 | 
                    
                            
              
                 | 
                    
                            
              
                |  Specimen Label: | 
                    Table S2 - E15.5 - Fgfr2 | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    3 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6172900 | 
                     
              
                |  Assay Type: | 
                    RNA in situ | 
                     
              
                |  Annotation Date: | 
                    2018-07-25 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Male | 
                     
              
                |  Emaps: | 
                    EMAPS:1689428 | 
                     
              
                |  Pattern: | 
                    Not Specified | 
                     
              
                |  Stage: | 
                    TS28 | 
                     
              
                |  Assay Id: | 
                    MGI:6190277 | 
                     
              
                |  Age: | 
                    postnatal day 4 | 
                     
              
                 | 
                    
                            
              
                 | 
                    
                            
              
                |  Specimen Label: | 
                    Table S2 - P4 - Fgfr2 | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    5 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6172900 | 
                     
              
                |  Assay Type: | 
                    RNA in situ | 
                     
              
                |  Annotation Date: | 
                    2018-07-25 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Male | 
                     
              
                |  Emaps: | 
                    EMAPS:1689428 | 
                     
              
                |  Pattern: | 
                    Not Specified | 
                     
              
                |  Stage: | 
                    TS28 | 
                     
              
                |  Assay Id: | 
                    MGI:6190277 | 
                     
              
                |  Age: | 
                    postnatal day 14 | 
                     
              
                 | 
                    
                            
              
                 | 
                    
                            
              
                |  Specimen Label: | 
                    Table S2 - P14 - Fgfr2 | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    6 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6172900 | 
                     
              
                |  Assay Type: | 
                    RNA in situ | 
                     
              
                |  Annotation Date: | 
                    2018-07-25 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Not Specified | 
                     
              
                |  Emaps: | 
                    EMAPS:1689419 | 
                     
              
                |  Pattern: | 
                    Not Specified | 
                     
              
                |  Stage: | 
                    TS19 | 
                     
              
                |  Assay Id: | 
                    MGI:6190277 | 
                     
              
                |  Age: | 
                    embryonic day 11.5 | 
                     
              
                 | 
                    
                            
              
                 | 
                    
                            
              
                |  Specimen Label: | 
                    Table S2 - E11.5 - Fgfr2 | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    1 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6172900 | 
                     
              
                |  Assay Type: | 
                    RNA in situ | 
                     
              
                |  Annotation Date: | 
                    2018-07-25 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Male | 
                     
              
                |  Emaps: | 
                    EMAPS:1689426 | 
                     
              
                |  Pattern: | 
                    Not Specified | 
                     
              
                |  Stage: | 
                    TS26 | 
                     
              
                |  Assay Id: | 
                    MGI:6190277 | 
                     
              
                |  Age: | 
                    embryonic day 18.5 | 
                     
              
                 | 
                    
                            
              
                 | 
                    
                            
              
                |  Specimen Label: | 
                    Table S2 - E18.5 - Fgfr2 | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    4 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | GXD Expression | 
              
                  
              
              
                |  Probe: | 
                    MGI:6172900 | 
                     
              
                |  Assay Type: | 
                    RNA in situ | 
                     
              
                |  Annotation Date: | 
                    2018-07-25 | 
                     
              
                |  Strength: | 
                    Present | 
                     
              
                |  Sex: | 
                    Male | 
                     
              
                |  Emaps: | 
                    EMAPS:1689428 | 
                     
              
                |  Pattern: | 
                    Not Specified | 
                     
              
                |  Stage: | 
                    TS28 | 
                     
              
                |  Assay Id: | 
                    MGI:6190277 | 
                     
              
                |  Age: | 
                    postnatal day 28 | 
                     
              
                 | 
                    
                            
              
                 | 
                    
                            
              
                |  Specimen Label: | 
                    Table S2 - P28 - Fgfr2 | 
                     
              
                |  Detected: | 
                    true | 
                     
              
                |  Specimen Num: | 
                    7 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Lin Y | 
                     
              
                |  Year: | 
                    2009 | 
                     
              
                |  Journal: | 
                    Dev Dyn | 
                     
              
                |  Title: | 
                    FGFR2 in the dental epithelium is essential for development and maintenance of the maxillary cervical loop, a stem cell niche in mouse incisors. | 
                     
              
                |  Volume: | 
                    238 | 
                     
              
                |  Issue: | 
                    2 | 
                     
              
                |  Pages: | 
                    324-30 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Ota S | 
                     
              
                |  Year: | 
                    2009 | 
                     
              
                |  Journal: | 
                    Hum Mol Genet | 
                     
              
                |  Title: | 
                    The role of senescence and prosurvival signaling in controlling the oncogenic activity of FGFR2 mutants associated with cancer and birth defects. | 
                     
              
                |  Volume: | 
                    18 | 
                     
              
                |  Issue: | 
                    14 | 
                     
              
                |  Pages: | 
                    2609-21 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Abler LL | 
                     
              
                |  Year: | 
                    2009 | 
                     
              
                |  Journal: | 
                    Dev Dyn | 
                     
              
                |  Title: | 
                    Conditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung. | 
                     
              
                |  Volume: | 
                    238 | 
                     
              
                |  Issue: | 
                    8 | 
                     
              
                |  Pages: | 
                    1999-2013 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Goissis MD | 
                     
              
                |  Year: | 
                    2023 | 
                     
              
                |  Journal: | 
                    PLoS One | 
                     
              
                |  Title: | 
                    Influence of FGF4 and BMP4 on FGFR2 dynamics during the segregation of epiblast and primitive endoderm cells in the pre-implantation mouse embryo. | 
                     
              
                |  Volume: | 
                    18 | 
                     
              
                |  Issue: | 
                    7 | 
                     
              
                |  Pages: | 
                    e0279515 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Yang J | 
                     
              
                |  Year: | 
                    2015 | 
                     
              
                |  Journal: | 
                    Cell Cycle | 
                     
              
                |  Title: | 
                    Binding of FGF2 to FGFR2 in an autocrine mode in trophectoderm cells is indispensable for mouse blastocyst formation through PKC-p38 pathway. | 
                     
              
                |  Volume: | 
                    14 | 
                     
              
                |  Issue: | 
                    20 | 
                     
              
                |  Pages: | 
                    3318-30 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Sims-Lucas S | 
                     
              
                |  Year: | 
                    2011 | 
                     
              
                |  Journal: | 
                    Dev Dyn | 
                     
              
                |  Title: | 
                    Fgfr1 and the IIIc isoform of Fgfr2 play critical roles in the metanephric mesenchyme mediating early inductive events in kidney development. | 
                     
              
                |  Volume: | 
                    240 | 
                     
              
                |  Issue: | 
                    1 | 
                     
              
                |  Pages: | 
                    240-9 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Kuslak SL | 
                     
              
                |  Year: | 
                    2007 | 
                     
              
                |  Journal: | 
                    Development | 
                     
              
                |  Title: | 
                    The mouse seminal vesicle shape mutation is allelic with Fgfr2. | 
                     
              
                |  Volume: | 
                    134 | 
                     
              
                |  Issue: | 
                    3 | 
                     
              
                |  Pages: | 
                    557-65 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Hibberd CE | 
                     
              
                |  Year: | 
                    2016 | 
                     
              
                |  Journal: | 
                    Am J Med Genet A | 
                     
              
                |  Title: | 
                    FGFR-associated craniosynostosis syndromes and gastrointestinal defects. | 
                     
              
                |  Volume: | 
                    170 | 
                     
              
                |  Issue: | 
                    12 | 
                     
              
                |  Pages: | 
                    3215-3221 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Molotkov A | 
                     
              
                |  Year: | 
                    2018 | 
                     
              
                |  Journal: | 
                    Dev Biol | 
                     
              
                |  Title: | 
                    Distinct mechanisms for PDGF and FGF signaling in primitive endoderm development. | 
                     
              
                |  Volume: | 
                    442 | 
                     
              
                |  Issue: | 
                    1 | 
                     
              
                |  Pages: | 
                    155-161 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Kurowski A | 
                     
              
                |  Year: | 
                    2019 | 
                     
              
                |  Journal: | 
                    Dev Biol | 
                     
              
                |  Title: | 
                    FGFR1 regulates trophectoderm development and facilitates blastocyst implantation. | 
                     
              
                |  Volume: | 
                    446 | 
                     
              
                |  Issue: | 
                    1 | 
                     
              
                |  Pages: | 
                    94-101 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Ray AT | 
                     
              
                |  Year: | 
                    2023 | 
                     
              
                |  Journal: | 
                    Development | 
                     
              
                |  Title: | 
                    FGF signaling regulates salivary gland branching morphogenesis by modulating cell adhesion. | 
                     
              
                |  Volume: | 
                    150 | 
                     
              
                |  Issue: | 
                    6 | 
                     
              
                 | 
                    
                            
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Nguyen MB | 
                     
              
                |  Year: | 
                    2018 | 
                     
              
                |  Journal: | 
                    Nat Commun | 
                     
              
                |  Title: | 
                    FGF signalling controls the specification of hair placode-derived SOX9 positive progenitors to Merkel cells. | 
                     
              
                |  Volume: | 
                    9 | 
                     
              
                |  Issue: | 
                    1 | 
                     
              
                |  Pages: | 
                    2333 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Ray AT | 
                     
              
                |  Year: | 
                    2020 | 
                     
              
                |  Journal: | 
                    Genes Dev | 
                     
              
                |  Title: | 
                    FGF signaling regulates development by processes beyond canonical pathways. | 
                     
              
                |  Volume: | 
                    34 | 
                     
              
                |  Issue: | 
                    23-24 | 
                     
              
                |  Pages: | 
                    1735-1752 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Aoyama E | 
                     
              
                |  Year: | 
                    2012 | 
                     
              
                |  Journal: | 
                    FEBS Lett | 
                     
              
                |  Title: | 
                    CCN2/CTGF binds to fibroblast growth factor receptor 2 and modulates its signaling. | 
                     
              
                |  Volume: | 
                    586 | 
                     
              
                |  Issue: | 
                    24 | 
                     
              
                |  Pages: | 
                    4270-5 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   | 
          
              | Publication | 
              
                  
              
              
                |  First Author: | 
                    Wilke TA | 
                     
              
                |  Year: | 
                    1997 | 
                     
              
                |  Journal: | 
                    Dev Dyn | 
                     
              
                |  Title: | 
                    Expression of fibroblast growth factor receptors (FGFR1, FGFR2, FGFR3) in the developing head and face. | 
                     
              
                |  Volume: | 
                    210 | 
                     
              
                |  Issue: | 
                    1 | 
                     
              
                |  Pages: | 
                    41-52 | 
                     
               
               | 
              
              
              
               • 
                  • 
                  • 
                  • 
                  • 
                   |