|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 1993 for Fgfr3

<< First    < Previous  |  Next >    Last >>
0.023s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein
Organism: Mus musculus
Length: 140  
Fragment?: false
Publication
First Author: Su N
Year: 2010
Journal: Int J Biol Sci
Title: Generation of Fgfr3 conditional knockout mice.
Volume: 6
Issue: 4
Pages: 327-32
Allele
Name: transgene insertion 4-2, William D Richardson
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Publication
First Author: Moldrich RX
Year: 2011
Journal: Dev Dyn
Title: Fgfr3 regulates development of the caudal telencephalon.
Volume: 240
Issue: 6
Pages: 1586-99
Strain
Attribute String: mutant stock, transgenic
Publication
First Author: Slezak M
Year: 2019
Journal: Curr Biol
Title: Distinct Mechanisms for Visual and Motor-Related Astrocyte Responses in Mouse Visual Cortex.
Volume: 29
Issue: 18
Pages: 3120-3127.e5
Publication
First Author: Xie Y
Year: 2017
Journal: Int J Biol Sci
Title: FGFR3 deficient mice have accelerated fracture repair.
Volume: 13
Issue: 8
Pages: 1029-1037
Publication  
First Author: Lee YC
Year: 2017
Journal: Sci Rep
Title: Knock-in human FGFR3 achondroplasia mutation as a mouse model for human skeletal dysplasia.
Volume: 7
Pages: 43220
Publication
First Author: Garcia S
Year: 2013
Journal: Sci Transl Med
Title: Postnatal soluble FGFR3 therapy rescues achondroplasia symptoms and restores bone growth in mice.
Volume: 5
Issue: 203
Pages: 203ra124
Publication
First Author: Shazeeb MS
Year: 2018
Journal: Sci Rep
Title: Skeletal Characterization of the Fgfr3 Mouse Model of Achondroplasia Using Micro-CT and MRI Volumetric Imaging.
Volume: 8
Issue: 1
Pages: 469
Publication
First Author: Zhou S
Year: 2015
Journal: PLoS Genet
Title: FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling.
Volume: 11
Issue: 6
Pages: e1005214
Publication
First Author: Foth M
Year: 2018
Journal: J Pathol
Title: FGFR3 mutation increases bladder tumourigenesis by suppressing acute inflammation.
Volume: 246
Issue: 3
Pages: 331-343
Publication
First Author: Wen X
Year: 2016
Journal: J Biol Chem
Title: Chondrocyte FGFR3 Regulates Bone Mass by Inhibiting Osteogenesis.
Volume: 291
Issue: 48
Pages: 24912-24921
Publication
First Author: Di Rocco F
Year: 2014
Journal: Hum Mol Genet
Title: FGFR3 mutation causes abnormal membranous ossification in achondroplasia.
Volume: 23
Issue: 11
Pages: 2914-25
Publication  
First Author: Anttonen T
Year: 2017
Journal: eNeuro
Title: Cytoskeletal Stability in the Auditory Organ In Vivo: RhoA Is Dispensable for Wound Healing but Essential for Hair Cell Development.
Volume: 4
Issue: 5
Publication
First Author: Liu S
Year: 2008
Journal: J Am Soc Nephrol
Title: FGFR3 and FGFR4 do not mediate renal effects of FGF23.
Volume: 19
Issue: 12
Pages: 2342-50
Publication
First Author: Huang JY
Year: 2020
Journal: Sci Rep
Title: Enhanced FGFR3 activity in postmitotic principal neurons during brain development results in cortical dysplasia and axonal tract abnormality.
Volume: 10
Issue: 1
Pages: 18508
Publication
First Author: Rivers LE
Year: 2008
Journal: Nat Neurosci
Title: PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice.
Volume: 11
Issue: 12
Pages: 1392-401
Publication
First Author: Kirjavainen A
Year: 2015
Journal: Biol Open
Title: The Rho GTPase Cdc42 regulates hair cell planar polarity and cellular patterning in the developing cochlea.
Volume: 4
Issue: 4
Pages: 516-26
Publication  
First Author: Anttonen T
Year: 2012
Journal: Sci Rep
Title: Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood.
Volume: 2
Pages: 978
Publication  
First Author: Osawa Y
Year: 2017
Journal: Bone
Title: Activated FGFR3 promotes bone formation via accelerating endochondral ossification in mouse model of distraction osteogenesis.
Volume: 105
Pages: 42-49
Publication
First Author: Zawadzka M
Year: 2010
Journal: Cell Stem Cell
Title: CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.
Volume: 6
Issue: 6
Pages: 578-90
Publication  
First Author: Maass JC
Year: 2015
Journal: Front Cell Neurosci
Title: Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea.
Volume: 9
Pages: 110
Publication
First Author: Kolla L
Year: 2020
Journal: Nat Commun
Title: Characterization of the development of the mouse cochlear epithelium at the single cell level.
Volume: 11
Issue: 1
Pages: 2389
Publication
First Author: Ellis K
Year: 2019
Journal: Dev Biol
Title: GSK3 regulates hair cell fate in the developing mammalian cochlea.
Volume: 453
Issue: 2
Pages: 191-205
Publication
First Author: Young KM
Year: 2010
Journal: Glia
Title: An Fgfr3-iCreER(T2) transgenic mouse line for studies of neural stem cells and astrocytes.
Volume: 58
Issue: 8
Pages: 943-53
Publication
First Author: Walters BJ
Year: 2017
Journal: Cell Rep
Title: In Vivo Interplay between p27Kip1, GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice.
Volume: 19
Issue: 2
Pages: 307-320
Publication
First Author: Liu Z
Year: 2012
Journal: J Neurosci
Title: Regulation of p27Kip1 by Sox2 maintains quiescence of inner pillar cells in the murine auditory sensory epithelium.
Volume: 32
Issue: 31
Pages: 10530-40
Publication
First Author: Xiong W
Year: 2019
Journal: J Neurosci
Title: Astrocytic Epoxyeicosatrienoic Acid Signaling in the Medial Prefrontal Cortex Modulates Depressive-like Behaviors.
Volume: 39
Issue: 23
Pages: 4606-4623
Publication  
First Author: Laos M
Year: 2017
Journal: Sci Rep
Title: Indispensable role of Mdm2/p53 interaction during the embryonic and postnatal inner ear development.
Volume: 7
Pages: 42216
Publication
First Author: Yamashita T
Year: 2018
Journal: PLoS Genet
Title: High-resolution transcriptional dissection of in vivo Atoh1-mediated hair cell conversion in mature cochleae identifies Isl1 as a co-reprogramming factor.
Volume: 14
Issue: 7
Pages: e1007552
Publication
First Author: Chrysostomou E
Year: 2020
Journal: J Neurosci
Title: The Notch Ligand Jagged1 Is Required for the Formation, Maintenance, and Survival of Hensen's Cells in the Mouse Cochlea.
Volume: 40
Issue: 49
Pages: 9401-9413
Publication
First Author: Leng L
Year: 2018
Journal: Neuron
Title: Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation.
Volume: 100
Issue: 3
Pages: 551-563.e7
Publication
First Author: Chen J
Year: 2005
Journal: Blood
Title: Constitutively activated FGFR3 mutants signal through PLCgamma-dependent and -independent pathways for hematopoietic transformation.
Volume: 106
Issue: 1
Pages: 328-37
Publication
First Author: Zhang J
Year: 2018
Journal: Eur J Neurosci
Title: ERBB2 signaling drives supporting cell proliferation in vitro and apparent supernumerary hair cell formation in vivo in the neonatal mouse cochlea.
Volume: 48
Issue: 10
Pages: 3299-3316
Publication  
First Author: Campbell DP
Year: 2016
Journal: Sci Rep
Title: Canonical Notch signaling plays an instructive role in auditory supporting cell development.
Volume: 6
Pages: 19484
Publication
First Author: Pannier S
Year: 2010
Journal: Bone
Title: Delayed bone age due to a dual effect of FGFR3 mutation in Achondroplasia.
Volume: 47
Issue: 5
Pages: 905-15
Publication  
First Author: Ghimire SR
Year: 2018
Journal: Development
Title: A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea.
Volume: 145
Issue: 12
Publication
First Author: Liu Z
Year: 2012
Journal: J Neurosci
Title: Age-dependent in vivo conversion of mouse cochlear pillar and Deiters' cells to immature hair cells by Atoh1 ectopic expression.
Volume: 32
Issue: 19
Pages: 6600-10
Publication
First Author: Su N
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Gain-of-function mutation of FGFR3 results in impaired fracture healing due to inhibition of chondrocyte differentiation.
Volume: 376
Issue: 3
Pages: 454-9
Publication
First Author: Arnaud-Dabernat S
Year: 2007
Journal: Diabetes
Title: FGFR3 is a negative regulator of the expansion of pancreatic epithelial cells.
Volume: 56
Issue: 1
Pages: 96-106
Publication
First Author: Cox BC
Year: 2012
Journal: J Assoc Res Otolaryngol
Title: Conditional gene expression in the mouse inner ear using Cre-loxP.
Volume: 13
Issue: 3
Pages: 295-322
Publication
First Author: Mugniery E
Year: 2012
Journal: Hum Mol Genet
Title: An activating Fgfr3 mutation affects trabecular bone formation via a paracrine mechanism during growth.
Volume: 21
Issue: 11
Pages: 2503-13
Publication
First Author: Dunois-Lardé C
Year: 2005
Journal: Mol Carcinog
Title: Absence of FGFR3 mutations in urinary bladder tumours of rats and mice treated with N-butyl-N-(-4-hydroxybutyl)nitrosamine.
Volume: 42
Issue: 3
Pages: 142-9
Publication  
First Author: Zhou S
Year: 2016
Journal: Sci Rep
Title: Conditional Deletion of Fgfr3 in Chondrocytes leads to Osteoarthritis-like Defects in Temporomandibular Joint of Adult Mice.
Volume: 6
Pages: 24039
Publication
First Author: Iwata T
Year: 2001
Journal: Hum Mol Genet
Title: Highly activated Fgfr3 with the K644M mutation causes prolonged survival in severe dwarf mice.
Volume: 10
Issue: 12
Pages: 1255-64
Publication
First Author: Chen L
Year: 1999
Journal: J Clin Invest
Title: Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis.
Volume: 104
Issue: 11
Pages: 1517-25
Publication
First Author: Lorget F
Year: 2012
Journal: Am J Hum Genet
Title: Evaluation of the therapeutic potential of a CNP analog in a Fgfr3 mouse model recapitulating achondroplasia.
Volume: 91
Issue: 6
Pages: 1108-14
Publication
First Author: Usha AP
Year: 1997
Journal: Anim Genet
Title: Dwarfism in Dexter cattle is not caused by the mutations in FGFR3 responsible for achondroplasia in humans.
Volume: 28
Issue: 1
Pages: 55-7
Publication
First Author: Martin L
Year: 2018
Journal: Hum Mol Genet
Title: Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.
Volume: 27
Issue: 1
Pages: 1-13
Publication
First Author: Inglis-Broadgate SL
Year: 2005
Journal: Dev Biol
Title: FGFR3 regulates brain size by controlling progenitor cell proliferation and apoptosis during embryonic development.
Volume: 279
Issue: 1
Pages: 73-85
Publication
First Author: de Frutos CA
Year: 2007
Journal: Dev Cell
Title: Snail1 is a transcriptional effector of FGFR3 signaling during chondrogenesis and achondroplasias.
Volume: 13
Issue: 6
Pages: 872-83
Publication
First Author: Matsushita T
Year: 2009
Journal: Hum Mol Genet
Title: FGFR3 promotes synchondrosis closure and fusion of ossification centers through the MAPK pathway.
Volume: 18
Issue: 2
Pages: 227-40
Publication
First Author: Qi H
Year: 2014
Journal: Biochim Biophys Acta
Title: FGFR3 induces degradation of BMP type I receptor to regulate skeletal development.
Volume: 1843
Issue: 7
Pages: 1237-47
Publication
First Author: Li H
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype.
Volume: 300
Issue: 3
Pages: E508-17
Publication
First Author: Jin M
Year: 2012
Journal: Hum Mol Genet
Title: A novel FGFR3-binding peptide inhibits FGFR3 signaling and reverses the lethal phenotype of mice mimicking human thanatophoric dysplasia.
Volume: 21
Issue: 26
Pages: 5443-55
Publication
First Author: Wang Q
Year: 2001
Journal: Development
Title: Differential regulation of endochondral bone growth and joint development by FGFR1 and FGFR3 tyrosine kinase domains.
Volume: 128
Issue: 19
Pages: 3867-76
Publication
First Author: Kuang L
Year: 2020
Journal: Ann Rheum Dis
Title: FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice.
Volume: 79
Issue: 1
Pages: 112-122
Publication
First Author: Ota S
Year: 2016
Journal: Hum Mol Genet
Title: HDAC6 deficiency or inhibition blocks FGFR3 accumulation and improves bone growth in a model of achondroplasia.
Volume: 25
Issue: 19
Pages: 4227-4243
Publication
First Author: Iwata T
Year: 2000
Journal: Hum Mol Genet
Title: A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos.
Volume: 9
Issue: 11
Pages: 1603-13
Publication
First Author: Hayashi T
Year: 2007
Journal: Dev Dyn
Title: Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti.
Volume: 236
Issue: 2
Pages: 525-33
Publication
First Author: Zhou ZQ
Year: 2015
Journal: Hum Mol Genet
Title: Mutant activated FGFR3 impairs endochondral bone growth by preventing SOX9 downregulation in differentiating chondrocytes.
Volume: 24
Issue: 6
Pages: 1764-73
Publication
First Author: Jonquoy A
Year: 2012
Journal: Hum Mol Genet
Title: A novel tyrosine kinase inhibitor restores chondrocyte differentiation and promotes bone growth in a gain-of-function Fgfr3 mouse model.
Volume: 21
Issue: 4
Pages: 841-51
Publication
First Author: Logié A
Year: 2005
Journal: Hum Mol Genet
Title: Activating mutations of the tyrosine kinase receptor FGFR3 are associated with benign skin tumors in mice and humans.
Volume: 14
Issue: 9
Pages: 1153-60
Publication
First Author: Pannier S
Year: 2009
Journal: Biochim Biophys Acta
Title: Activating Fgfr3 Y367C mutation causes hearing loss and inner ear defect in a mouse model of chondrodysplasia.
Volume: 1792
Issue: 2
Pages: 140-7
Publication
First Author: Blak AA
Year: 2007
Journal: Dev Biol
Title: Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain.
Volume: 303
Issue: 1
Pages: 231-43
Publication
First Author: Su N
Year: 2010
Journal: Hum Mol Genet
Title: Gain-of-function mutation in FGFR3 in mice leads to decreased bone mass by affecting both osteoblastogenesis and osteoclastogenesis.
Volume: 19
Issue: 7
Pages: 1199-210
Publication
First Author: Pringle NP
Year: 2003
Journal: Development
Title: Fgfr3 expression by astrocytes and their precursors: evidence that astrocytes and oligodendrocytes originate in distinct neuroepithelial domains.
Volume: 130
Issue: 1
Pages: 93-102
Publication
First Author: Kang W
Year: 2019
Journal: Stem Cell Reports
Title: Transient Redirection of SVZ Stem Cells to Oligodendrogenesis by FGFR3 Activation Promotes Remyelination.
Volume: 12
Issue: 6
Pages: 1223-1231
Publication
First Author: Perez-Castro AV
Year: 1997
Journal: Genomics
Title: Genomic organization of the human fibroblast growth factor receptor 3 (FGFR3) gene and comparative sequence analysis with the mouse Fgfr3 gene.
Volume: 41
Issue: 1
Pages: 10-6
Publication
First Author: Shung CY
Year: 2012
Journal: Hum Mol Genet
Title: Disruption of a Sox9-β-catenin circuit by mutant Fgfr3 in thanatophoric dysplasia type II.
Volume: 21
Issue: 21
Pages: 4628-44
Publication
First Author: Ahmad I
Year: 2011
Journal: Dis Model Mech
Title: K-Ras and β-catenin mutations cooperate with Fgfr3 mutations in mice to promote tumorigenesis in the skin and lung, but not in the bladder.
Volume: 4
Issue: 4
Pages: 548-55
Publication
First Author: Jungnickel J
Year: 2005
Journal: Neuroscience
Title: Regulation of neuronal death and calcitonin gene-related peptide by fibroblast growth factor-2 and FGFR3 after peripheral nerve injury: evidence from mouse mutants.
Volume: 134
Issue: 4
Pages: 1343-50
Publication      
First Author: Harris BS
Year: 2011
Journal: MGI Direct Data Submission
Title: A new spontaneous mutation in Fgfr3
Publication
First Author: Nakajima A
Year: 2003
Journal: Endocrinology
Title: Expression of fibroblast growth factor receptor-3 (FGFR3), signal transducer and activator of transcription-1, and cyclin-dependent kinase inhibitor p21 during endochondral ossification: differential role of FGFR3 in skeletal development and fracture repair.
Volume: 144
Issue: 10
Pages: 4659-68
Publication
First Author: Gonçalves D
Year: 2020
Journal: PLoS One
Title: In vitro and in vivo characterization of Recifercept, a soluble fibroblast growth factor receptor 3, as treatment for achondroplasia.
Volume: 15
Issue: 12
Pages: e0244368
Publication
First Author: Yamashita A
Year: 2014
Journal: Nature
Title: Statin treatment rescues FGFR3 skeletal dysplasia phenotypes.
Volume: 513
Issue: 7519
Pages: 507-11
Publication
First Author: Segev O
Year: 2000
Journal: Hum Mol Genet
Title: Restrained chondrocyte proliferation and maturation with abnormal growth plate vascularization and ossification in human FGFR-3(G380R) transgenic mice.
Volume: 9
Issue: 2
Pages: 249-58
UniProt Feature
Begin: 529
Description: Phosphotyrosine; by FGFR3
Type: modified residue
End: 529
Publication
First Author: Wang Y
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: A mouse model for achondroplasia produced by targeting fibroblast growth factor receptor 3.
Volume: 96
Issue: 8
Pages: 4455-60
Publication
First Author: Naski MC
Year: 1998
Journal: Development
Title: Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3.
Volume: 125
Issue: 24
Pages: 4977-88
Publication
First Author: Davidson D
Year: 2005
Journal: J Biol Chem
Title: Fibroblast growth factor (FGF) 18 signals through FGF receptor 3 to promote chondrogenesis.
Volume: 280
Issue: 21
Pages: 20509-15
Publication
First Author: Colvin JS
Year: 1996
Journal: Nat Genet
Title: Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3.
Volume: 12
Issue: 4
Pages: 390-7
Publication
First Author: Twigg SR
Year: 2009
Journal: Dev Dyn
Title: Skeletal analysis of the Fgfr3(P244R) mouse, a genetic model for the Muenke craniosynostosis syndrome.
Volume: 238
Issue: 2
Pages: 331-42
Publication
First Author: Jungnickel J
Year: 2004
Journal: Mol Cell Neurosci
Title: Fibroblast growth factor receptor 3 signaling regulates injury-related effects in the peripheral nervous system.
Volume: 25
Issue: 1
Pages: 21-9
Publication
First Author: Cho JY
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia.
Volume: 101
Issue: 2
Pages: 609-14
Publication
First Author: Lin T
Year: 2003
Journal: Hum Mol Genet
Title: A central nervous system specific mouse model for thanatophoric dysplasia type II.
Volume: 12
Issue: 21
Pages: 2863-71
Publication
First Author: Perez-Castro AV
Year: 1995
Journal: Genomics
Title: Genomic organization of the mouse fibroblast growth factor receptor 3 (Fgfr3) gene.
Volume: 30
Issue: 2
Pages: 157-62
Publication
First Author: Wuechner C
Year: 1996
Journal: Int J Dev Biol
Title: Developmental expression of splicing variants of fibroblast growth factor receptor 3 (FGFR3) in mouse.
Volume: 40
Issue: 6
Pages: 1185-8
Publication  
First Author: Piombo V
Year: 2018
Journal: Bone
Title: Signaling systems affecting the severity of multiple osteochondromas.
Volume: 111
Pages: 71-81
Publication
First Author: Wilkie AO
Year: 1997
Journal: Hum Mol Genet
Title: Craniosynostosis: genes and mechanisms.
Volume: 6
Issue: 10
Pages: 1647-56
Publication
First Author: Jang JH
Year: 2001
Journal: Cancer Res
Title: Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers.
Volume: 61
Issue: 9
Pages: 3541-3
Publication
First Author: Chen L
Year: 2001
Journal: Hum Mol Genet
Title: A Ser(365)-->Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia.
Volume: 10
Issue: 5
Pages: 457-65
Publication
First Author: Oh LY
Year: 2003
Journal: J Neurosci
Title: Fibroblast growth factor receptor 3 signaling regulates the onset of oligodendrocyte terminal differentiation.
Volume: 23
Issue: 3
Pages: 883-94
Publication
First Author: Komla-Ebri D
Year: 2016
Journal: J Clin Invest
Title: Tyrosine kinase inhibitor NVP-BGJ398 functionally improves FGFR3-related dwarfism in mouse model.
Volume: 126
Issue: 5
Pages: 1871-84
Publication
First Author: Peters K
Year: 1993
Journal: Dev Biol
Title: Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis.
Volume: 155
Issue: 2
Pages: 423-30