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Search results 1 to 100 out of 1253 for Fgfr4

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Hits by Pathway

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Type Details Score
Gene
2264 | FGFR4
Type: gene
Organism: human
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Gene
317696 | FGFR4
Type: gene
Organism: cattle
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Gene
395603 | FGFR4
Type: gene
Organism: chicken
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Gene
100000160 | fgfr4
Type: gene
Organism: zebrafish
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Gene
698494 | FGFR4
Type: gene
Organism: macaque, rhesus
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Gene
549077 | fgfr4
Type: gene
Organism: frog, western clawed
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Gene
25114 | Fgfr4
Type: gene
Organism: rat
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Gene
489095 | FGFR4
Type: gene
Organism: dog, domestic
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Gene
462301 | FGFR4
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:95525 | Fgfr4
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
109279841 | LOC109279841
Type: gene
Organism: human
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GXD Expression
GXD Expression
     
Probe: MGI:5556220
Assay Type: Northern blot
Annotation Date: 2014-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737323
Stage: TS23
Assay Id: MGI:5556257
Age: embryonic day 15.5
Specimen Label: Fgfr4
Detected: true
Specimen Num: 4
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Publication
20018895 | J:159751
First Author: Wu X
Year: 2010
Journal: J Biol Chem
Title: FGF19-induced hepatocyte proliferation is mediated through FGFR4 activation.
Volume: 285
Issue: 8
Pages: 5165-70
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Publication
24625004 | J:214140
First Author: Nakano-Tateno T
Year: 2014
Journal: Mol Endocrinol
Title: FGFR4 polymorphic variants modulate phenotypic features of Cushing disease.
Volume: 28
Issue: 4
Pages: 525-33
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Publication
22615798 | J:187236
First Author: French DM
Year: 2012
Journal: PLoS One
Title: Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse models.
Volume: 7
Issue: 5
Pages: e36713
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Publication
31575945 | J:284629
First Author: Taylor A
Year: 2019
Journal: Sci Rep
Title: FGFR4 does not contribute to progression of chronic kidney disease.
Volume: 9
Issue: 1
Pages: 14023
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Publication
26675719 | J:228280
First Author: Ulaganathan VK
Year: 2015
Journal: Nature
Title: Germline variant FGFR4  p.G388R exposes a membrane-proximal STAT3 binding site.
Volume: 528
Issue: 7583
Pages: 570-4
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Publication
18753255 | J:293843
First Author: Liu S
Year: 2008
Journal: J Am Soc Nephrol
Title: FGFR3 and FGFR4 do not mediate renal effects of FGF23.
Volume: 19
Issue: 12
Pages: 2342-50
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Publication
17664243 | J:126527
First Author: Huang X
Year: 2007
Journal: Diabetes
Title: FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver.
Volume: 56
Issue: 10
Pages: 2501-10
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Publication
18186042 | J:132070
First Author: Kwiatkowski BA
Year: 2008
Journal: J Cell Physiol
Title: FGFR4 and its novel splice form in myogenic cells: Interplay of glycosylation and tyrosine phosphorylation.
Volume: 215
Issue: 3
Pages: 803-17
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Publication
30541128 | J:295120
First Author: Lutz SZ
Year: 2019
Journal: J Clin Endocrinol Metab
Title: The Gly385(388)Arg Polymorphism of the FGFR4 Receptor Regulates Hepatic Lipogenesis Under Healthy Diet.
Volume: 104
Issue: 6
Pages: 2041-2053
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Publication
16267055 | J:105668
First Author: Zhao P
Year: 2006
Journal: J Biol Chem
Title: Fgfr4 is required for effective muscle regeneration in vivo. Delineation of a MyoD-Tead2-Fgfr4 transcriptional pathway.
Volume: 281
Issue: 1
Pages: 429-38
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Publication
21139072 | J:172318
First Author: Li H
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype.
Volume: 300
Issue: 3
Pages: E508-17
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Publication
22442730 | J:187036
First Author: Yang C
Year: 2012
Journal: PLoS One
Title: Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB.
Volume: 7
Issue: 3
Pages: e33870
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Publication
19706524 | J:151994
First Author: Wu X
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice.
Volume: 106
Issue: 34
Pages: 14379-84
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Publication
31758962 | J:301901
 
First Author: Han X
Year: 2020
Journal: J Mol Cell Cardiol
Title: FGF23 induced left ventricular hypertrophy mediated by FGFR4 signaling in the myocardium is attenuated by soluble Klotho in mice.
Volume: 138
Pages: 66-74
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GXD Expression
GXD Expression
   
Probe: MGI:6172904
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190279
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Fgfr4
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6172904
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190279
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Fgfr4
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6172904
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190279
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Fgfr4
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6172904
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190279
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Fgfr4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6172904
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190279
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Fgfr4
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6172904
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190279
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Fgfr4
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6172904
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190279
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Fgfr4
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:9155
Assay Type: RNA in situ
Annotation Date: 2001-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1774322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:2149385
Age: embryonic day 14.5
Image: 5B
Note: Present in the developing skeletal muscles, here in the mouth and neck region. Fgfr4 is present in skeletal muscle in greater amounts and is more widely distributed than Fgf6.
Specimen Label: 5B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:9155
Assay Type: RNA in situ
Annotation Date: 2001-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1788322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:2149385
Age: embryonic day 14.5
Image: 5D, 5F
Note: Expression is widely distributed throughout the tongue, including in the fibers surrounding the tongue. Fgfr4 is present in skeletal muscle in greater amounts and is more widely distributed than Fgf6.
Specimen Label: 5D, 5F
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:9155
Assay Type: RNA in situ
Annotation Date: 2001-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1788322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:2149385
Age: embryonic day 14.5
Image: 6D
Note: Expression is widely distributed throughout the tongue, including in the fibers surrounding the tongue. Fgfr4 is present in skeletal muscle in greater amounts and is more widely distributed than Fgf6.
Specimen Label: 6D
Detected: true
Specimen Num: 3
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Publication
- | J:265097
     
First Author: Turer E
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Modest.
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Protein
Q03142-2
Organism: Mus musculus/domesticus
Length: 753  
Fragment?: false
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Publication
16213224 | J:129677
First Author: Inagaki T
Year: 2005
Journal: Cell Metab
Title: Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis.
Volume: 2
Issue: 4
Pages: 217-25
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Publication
23747250 | J:199244
First Author: Ezzat S
Year: 2013
Journal: Cell Metab
Title: The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes.
Volume: 17
Issue: 6
Pages: 929-40
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Publication
7959747 | J:19349
First Author: Avraham KB
Year: 1994
Journal: Genomics
Title: Mapping of murine fibroblast growth factor receptors refines regions of homology between mouse and human chromosomes.
Volume: 21
Issue: 3
Pages: 656-8
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Publication
20068154 | J:156750
First Author: Seitzer N
Year: 2010
Journal: Cancer Res
Title: A single nucleotide change in the mouse genome accelerates breast cancer progression.
Volume: 70
Issue: 2
Pages: 802-12
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Publication
26437603 | J:235836
First Author: Grabner A
Year: 2015
Journal: Cell Metab
Title: Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy.
Volume: 22
Issue: 6
Pages: 1020-32
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Publication
12769260 | J:84134
First Author: Cool SM
Year: 2002
Journal: Histochem J
Title: Temporal and spatial expression of fibroblast growth factor receptor 4 isoforms in murine tissues.
Volume: 34
Issue: 6-7
Pages: 291-7
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Publication
25204652 | J:278698
First Author: Ge H
Year: 2014
Journal: J Biol Chem
Title: Fibroblast growth factor receptor 4 (FGFR4) deficiency improves insulin resistance and glucose metabolism under diet-induced obesity conditions.
Volume: 289
Issue: 44
Pages: 30470-80
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Publication
9690623 | J:48719
First Author: Olson DC
Year: 1998
Journal: Cell Growth Differ
Title: Fibroblast growth factor receptor 4, implicated in progression of islet cell carcinogenesis by its expression profile, does not contribute functionally.
Volume: 9
Issue: 7
Pages: 557-64
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Publication
29438108 | J:262861
First Author: Kogan D
Year: 2018
Journal: J Clin Invest
Title: STAT3-enhancing germline mutations contribute to tumor-extrinsic immune evasion.
Volume: 128
Issue: 5
Pages: 1867-1872
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Publication
21437243 | J:171687
First Author: Wu AL
Year: 2011
Journal: PLoS One
Title: FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways.
Volume: 6
Issue: 3
Pages: e17868
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Publication
8223280 | J:12606
First Author: deLapeyrière O
Year: 1993
Journal: Development
Title: Expression of the Fgf6 gene is restricted to developing skeletal muscle in the mouse embryo.
Volume: 118
Issue: 2
Pages: 601-11
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Publication
10809780 | J:62267
First Author: Yu C
Year: 2000
Journal: J Biol Chem
Title: Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4.
Volume: 275
Issue: 20
Pages: 15482-9
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Publication
22174695 | J:179809
First Author: Tateno T
Year: 2011
Journal: PLoS Genet
Title: The FGFR4-G388R polymorphism promotes mitochondrial STAT3 serine phosphorylation to facilitate pituitary growth hormone cell tumorigenesis.
Volume: 7
Issue: 12
Pages: e1002400
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Publication
12466116 | J:80535
First Author: Yu C
Year: 2002
Journal: Am J Pathol
Title: Increased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient mice.
Volume: 161
Issue: 6
Pages: 2003-10
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Publication
11027503 | J:64800
First Author: Becker M
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Identification and functional characterization of the human and murine fibroblast growth factor receptor 4 promoters.
Volume: 276
Issue: 2
Pages: 493-501
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Publication
29532565 | J:309031
First Author: Yamamoto M
Year: 2018
Journal: Cancer Sci
Title: Established gastric cancer cell lines transplantable into C57BL/6 mice show fibroblast growth factor receptor 4 promotion of tumor growth.
Volume: 109
Issue: 5
Pages: 1480-1492
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Publication
28512310 | J:274551
First Author: Grabner A
Year: 2017
Journal: Sci Rep
Title: FGF23/FGFR4-mediated left ventricular hypertrophy is reversible.
Volume: 7
Issue: 1
Pages: 1993
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Publication
15467729 | J:95146
First Author: Yu S
Year: 2004
Journal: Lab Invest
Title: Distinct transcriptional control and action of fibroblast growth factor receptor 4 in differentiating skeletal muscle cells.
Volume: 84
Issue: 12
Pages: 1571-80
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Publication
15750181 | J:99093
First Author: Yu C
Year: 2005
Journal: J Biol Chem
Title: Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids.
Volume: 280
Issue: 18
Pages: 17707-14
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Publication
17623664 | J:124949
First Author: Kurosu H
Year: 2007
Journal: J Biol Chem
Title: Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.
Volume: 282
Issue: 37
Pages: 26687-95
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Publication
25056539 | J:319133
First Author: Wang C
Year: 2014
Journal: Curr Mol Med
Title: Hepatocyte FRS2α is essential for the endocrine fibroblast growth factor to limit the amplitude of bile acid production induced by prandial activity.
Volume: 14
Issue: 6
Pages: 703-711
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Publication
20131355 | J:156926
First Author: Hayashi T
Year: 2010
Journal: Dev Dyn
Title: Expression patterns of FGF receptors in the developing mammalian cochlea.
Volume: 239
Issue: 3
Pages: 1019-26
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Publication
18593883 | J:137423
First Author: Lagha M
Year: 2008
Journal: Genes Dev
Title: Pax3 regulation of FGF signaling affects the progression of embryonic progenitor cells into the myogenic program.
Volume: 22
Issue: 13
Pages: 1828-37
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Publication
16284190 | J:118817
First Author: Gutierrez A
Year: 2006
Journal: Arterioscler Thromb Vasc Biol
Title: Bile acids decrease hepatic paraoxonase 1 expression and plasma high-density lipoprotein levels via FXR-mediated signaling of FGFR4.
Volume: 26
Issue: 2
Pages: 301-6
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Publication
19237543 | J:149773
First Author: Shin DJ
Year: 2009
Journal: J Biol Chem
Title: FGF15/FGFR4 integrates growth factor signaling with hepatic bile acid metabolism and insulin action.
Volume: 284
Issue: 17
Pages: 11110-20
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Publication
24259513 | J:206158
First Author: Gattineni J
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Regulation of renal phosphate transport by FGF23 is mediated by FGFR1 and FGFR4.
Volume: 306
Issue: 3
Pages: F351-8
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Publication
27457912 | J:324435
First Author: Singh S
Year: 2016
Journal: Kidney Int
Title: Fibroblast growth factor 23 directly targets hepatocytes to promote inflammation in chronic kidney disease.
Volume: 90
Issue: 5
Pages: 985-996
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Publication
29122839 | J:253669
First Author: Li R
Year: 2017
Journal: Development
Title: FGF receptors control alveolar elastogenesis.
Volume: 144
Issue: 24
Pages: 4563-4572
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Publication
27078042 | J:316613
First Author: Lai MS
Year: 2016
Journal: Organogenesis
Title: The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes.
Volume: 12
Issue: 2
Pages: 61-77
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Publication
16929488 | J:117979
First Author: Huang X
Year: 2006
Journal: Mol Carcinog
Title: Forced expression of hepatocyte-specific fibroblast growth factor 21 delays initiation of chemically induced hepatocarcinogenesis.
Volume: 45
Issue: 12
Pages: 934-42
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Publication
19515808 | J:150719
First Author: Gattineni J
Year: 2009
Journal: Am J Physiol Renal Physiol
Title: FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.
Volume: 297
Issue: 2
Pages: F282-91
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Publication
9664689 | J:48564
First Author: Kettunen P
Year: 1998
Journal: Dev Genet
Title: Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9.
Volume: 22
Issue: 4
Pages: 374-85
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Publication
12644244 | J:82654
First Author: Reid S
Year: 2003
Journal: Brain Res Dev Brain Res
Title: Differential expression of fibroblast growth factor receptors in the developing murine choroid plexus.
Volume: 141
Issue: 1-2
Pages: 15-24
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Publication
15788460 | J:98519
First Author: Grifone R
Year: 2005
Journal: Development
Title: Six1 and Six4 homeoproteins are required for Pax3 and Mrf expression during myogenesis in the mouse embryo.
Volume: 132
Issue: 9
Pages: 2235-49
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Publication
26074812 | J:242809
 
First Author: Yablonka-Reuveni Z
Year: 2015
Journal: Front Aging Neurosci
Title: Myogenic-specific ablation of Fgfr1 impairs FGF2-mediated proliferation of satellite cells at the myofiber niche but does not abolish the capacity for muscle regeneration.
Volume: 7
Pages: 85
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Publication
15576401 | J:94299
First Author: Serls AE
Year: 2005
Journal: Development
Title: Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung.
Volume: 132
Issue: 1
Pages: 35-47
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Publication
26595272 | J:228212
First Author: Cinque L
Year: 2015
Journal: Nature
Title: FGF signalling regulates bone growth through autophagy.
Volume: 528
Issue: 7581
Pages: 272-5
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Publication
20348033 | J:160766
First Author: Porntaveetus T
Year: 2010
Journal: Gene Expr Patterns
Title: Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse.
Volume: 10
Issue: 4-5
Pages: 193-8
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Publication
8901049 | J:32251
First Author: Rosenquist TA
Year: 1996
Journal: Dev Dyn
Title: Fibroblast growth factor signalling in the hair growth cycle: expression of the fibroblast growth factor receptor and ligand genes in the murine hair follicle.
Volume: 205
Issue: 4
Pages: 379-86
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Protein Coding Gene
MGP_CAROLIEiJ_G0018553 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020587 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020541 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020519 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020537 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020336 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_95525 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020971 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019850 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020296 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020419 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020398 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020495 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020427 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021014 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019606 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019912 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0019618 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019433 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1326315 | J:2028
First Author: Korhonen J
Year: 1992
Journal: Int J Dev Biol
Title: Expression of FGFR-4 mRNA in developing mouse tissues.
Volume: 36
Issue: 2
Pages: 323-9
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Publication
9324058 | J:42777
First Author: Puscheck EE
Year: 1997
Journal: Mol Cell Endocrinol
Title: Fibroblast growth factor receptor (FGFR)-4, but not FGFR-3 is expressed in the pregnant ovary.
Volume: 132
Issue: 1-2
Pages: 169-76
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GXD Expression
GXD Expression
     
Probe: MGI:2156155
Assay Type: Northern blot
Annotation Date: 2002-01-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2156282
Age: embryonic day 7.0
Specimen Label: 7 d.p.c.
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2156155
Assay Type: Northern blot
Annotation Date: 2002-01-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2156282
Age: embryonic day 11.0
Specimen Label: 11 d.p.c.
Detected: false
Specimen Num: 2
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