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Search results 1 to 100 out of 349 for Fgr

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0.062s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Lee JH
Year: 2011
Journal: J Immunol
Title: The Src family kinase Fgr is critical for activation of mast cells and IgE-mediated anaphylaxis in mice.
Volume: 187
Issue: 4
Pages: 1807-15
Publication
First Author: Continolo S
Year: 2005
Journal: Exp Cell Res
Title: The proto-oncogene Fgr regulates cell migration and this requires its plasma membrane localization.
Volume: 302
Issue: 2
Pages: 253-69
Publication
First Author: Lowell CA
Year: 1994
Journal: Genes Dev
Title: Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity.
Volume: 8
Issue: 4
Pages: 387-98
Publication
First Author: Mócsai A
Year: 1999
Journal: J Immunol
Title: Adhesion-dependent degranulation of neutrophils requires the Src family kinases Fgr and Hck.
Volume: 162
Issue: 2
Pages: 1120-6
Publication
First Author: Vicentini L
Year: 2002
Journal: J Immunol
Title: Fgr deficiency results in defective eosinophil recruitment to the lung during allergic airway inflammation.
Volume: 168
Issue: 12
Pages: 6446-54
Publication
First Author: King FJ
Year: 1990
Journal: Oncogene
Title: Molecular cloning and sequencing of the murine c-fgr gene.
Volume: 5
Issue: 3
Pages: 337-44
Publication
First Author: Fumagalli L
Year: 2007
Journal: J Immunol
Title: The Src family kinases Hck and Fgr regulate neutrophil responses to N-formyl-methionyl-leucyl-phenylalanine.
Volume: 178
Issue: 6
Pages: 3874-85
Publication
First Author: Meng F
Year: 1998
Journal: EMBO J
Title: A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration.
Volume: 17
Issue: 15
Pages: 4391-403
Publication
First Author: Tronick SR
Year: 1985
Journal: Proc Natl Acad Sci U S A
Title: Isolation and chromosomal localization of the human fgr protooncogene, a distinct member of the tyrosine kinase gene family.
Volume: 82
Issue: 19
Pages: 6595-9
Publication
First Author: Wetzel DM
Year: 2016
Journal: J Cell Sci
Title: The Src kinases Hck, Fgr and Lyn activate Arg to facilitate IgG-mediated phagocytosis and Leishmania infection.
Volume: 129
Issue: 16
Pages: 3130-43
Publication
First Author: Lowell CA
Year: 1996
Journal: J Cell Biol
Title: Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions.
Volume: 133
Issue: 4
Pages: 895-910
Publication
First Author: Giagulli C
Year: 2006
Journal: J Immunol
Title: The Src family kinases Hck and Fgr are dispensable for inside-out, chemoattractant-induced signaling regulating beta 2 integrin affinity and valency in neutrophils, but are required for beta 2 integrin-mediated outside-in signaling involved in sustained adhesion.
Volume: 177
Issue: 1
Pages: 604-11
Publication
First Author: Acín-Pérez R
Year: 2014
Journal: Cell Metab
Title: ROS-triggered phosphorylation of complex II by Fgr kinase regulates cellular adaptation to fuel use.
Volume: 19
Issue: 6
Pages: 1020-33
Publication
First Author: Yi TL
Year: 1989
Journal: Oncogene
Title: Cloning of the murine c-fgr proto-oncogene cDNA and induction of c-fgr expression by proliferation and activation factors in normal bone marrow-derived monocytic cells.
Volume: 4
Issue: 9
Pages: 1081-7
Publication
First Author: Baruzzi A
Year: 2010
Journal: FEBS Lett
Title: c-Abl and Src-family kinases cross-talk in regulation of myeloid cell migration.
Volume: 584
Issue: 1
Pages: 15-21
Publication
First Author: Vines CM
Year: 2001
Journal: Immunity
Title: Inhibition of beta 2 integrin receptor and Syk kinase signaling in monocytes by the Src family kinase Fgr.
Volume: 15
Issue: 4
Pages: 507-19
Publication
First Author: Zhang H
Year: 2005
Journal: Immunity
Title: The Src family kinases Hck and Fgr negatively regulate neutrophil and dendritic cell chemokine signaling via PIR-B.
Volume: 22
Issue: 2
Pages: 235-46
Publication
First Author: Sasanuma H
Year: 2006
Journal: Blood
Title: Dual function for the adaptor MIST in IFN-gamma production by NK and CD4+NKT cells regulated by the Src kinase Fgr.
Volume: 107
Issue: 9
Pages: 3647-55
Publication
First Author: Zarbock A
Year: 2008
Journal: J Exp Med
Title: PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling.
Volume: 205
Issue: 10
Pages: 2339-47
Publication
First Author: Abe K
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Gain-of-function mutations in a member of the Src family kinases cause autoinflammatory bone disease in mice and humans.
Volume: 116
Issue: 24
Pages: 11872-11877
Publication
First Author: Abe K
Year: 2006
Journal: Mamm Genome
Title: New ENU-induced semidominant mutation, Ali18, causes inflammatory arthritis, dermatitis, and osteoporosis in the mouse.
Volume: 17
Issue: 9
Pages: 915-26
Publication      
First Author: Abe K
Year: 2017
Journal: EMBL Conference Mammalian Genetics and Genomics
Title: Novel Gain-of-Function Mutations in a Member of the Src Family Tyrosine Kinases Cause Autoinflammatory Bone Disease in the Mouse and Human.
Publication
First Author: Abe K
Year: 2009
Journal: Mamm Genome
Title: Genome-wide search for genes that modulate inflammatory arthritis caused by Ali18 mutation in mice.
Volume: 20
Issue: 3
Pages: 152-61
Publication  
First Author: Suen PW
Year: 1999
Journal: J Cell Sci
Title: Impaired integrin-mediated signal transduction, altered cytoskeletal structure and reduced motility in Hck/Fgr deficient macrophages.
Volume: 112 ( Pt 22)
Pages: 4067-78
Publication
First Author: Abe K
Year: 2008
Journal: Rheumatology (Oxford)
Title: Novel lymphocyte-independent mechanisms to initiate inflammatory arthritis via bone marrow-derived cells of Ali18 mutant mice.
Volume: 47
Issue: 3
Pages: 292-300
Publication
First Author: Jain M
Year: 2004
Journal: Circulation
Title: Increased myocardial dysfunction after ischemia-reperfusion in mice lacking glucose-6-phosphate dehydrogenase.
Volume: 109
Issue: 7
Pages: 898-903
Publication
First Author: Harrison MJ
Year: 2018
Journal: J Cell Mol Med
Title: Signalling through Src family kinase isoforms is not redundant in models of thrombo-inflammatory vascular disease.
Volume: 22
Issue: 9
Pages: 4317-4327
Publication
First Author: Medina I
Year: 2015
Journal: Circulation
Title: Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility.
Volume: 132
Issue: 6
Pages: 490-501
Publication
First Author: Scapini P
Year: 2004
Journal: J Immunol
Title: CXCL1/macrophage inflammatory protein-2-induced angiogenesis in vivo is mediated by neutrophil-derived vascular endothelial growth factor-A.
Volume: 172
Issue: 8
Pages: 5034-40
Publication
First Author: Caveggion E
Year: 2003
Journal: J Cell Physiol
Title: Expression and tyrosine phosphorylation of Cbl regulates macrophage chemokinetic and chemotactic movement.
Volume: 195
Issue: 2
Pages: 276-89
Publication
First Author: Lowell CA
Year: 1996
Journal: Blood
Title: Deficiency of the Hck and Src tyrosine kinases results in extreme levels of extramedullary hematopoiesis.
Volume: 87
Issue: 5
Pages: 1780-92
Publication
First Author: Hatakeyama S
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: The murine c-fgr gene product associated with Ly6C and p70 integral membrane protein is expressed in cells of a monocyte/macrophage lineage.
Volume: 91
Issue: 8
Pages: 3458-62
Publication
First Author: Meng F
Year: 1997
Journal: J Exp Med
Title: Lipopolysaccharide (LPS)-induced macrophage activation and signal transduction in the absence of Src-family kinases Hck, Fgr, and Lyn.
Volume: 185
Issue: 9
Pages: 1661-70
Publication
First Author: Baruzzi A
Year: 2012
Journal: Eur J Immunol
Title: The tyrosine kinase Abl is a component of macrophage podosomes and is required for podosome formation and function.
Volume: 42
Issue: 10
Pages: 2720-6
Publication
First Author: Sarantos MR
Year: 2008
Journal: J Immunol
Title: Transmigration of neutrophils across inflamed endothelium is signaled through LFA-1 and Src family kinase.
Volume: 181
Issue: 12
Pages: 8660-9
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Parker RC
Year: 1985
Journal: Mol Cell Biol
Title: Isolation of duplicated human c-src genes located on chromosomes 1 and 20.
Volume: 5
Issue: 4
Pages: 831-8
Publication
First Author: Podhipleux N
Year: 1995
Journal: Oncogene
Title: Isolation and characterization of the murine C-FGR genomic locus: exons IB-XII.
Volume: 11
Issue: 4
Pages: 781-4
GXD Expression    
Probe: MGI:7509352
Assay Type: RT-PCR
Annotation Date: 2023-07-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737319
Stage: TS19
Assay Id: MGI:7509382
Age: embryonic day 11.5
Image: 8
Specimen Label: E11.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7509352
Assay Type: RT-PCR
Annotation Date: 2023-07-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737321
Stage: TS21
Assay Id: MGI:7509382
Age: embryonic day 13.5
Image: 8
Specimen Label: E13.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7509352
Assay Type: RT-PCR
Annotation Date: 2023-07-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7509382
Age: postnatal adult
Image: 8
Specimen Label: Adult Kid
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1698120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5618255
Age: embryonic day 12.5
Specimen Label: not shown E12
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689517
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5618255
Age: embryonic day 10.5
Note: Expression was dorsal.
Specimen Label: not shown E10
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5618255
Age: embryonic day 11.5
Note: Expression was dorsal.
Specimen Label: not shown E11
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5618255
Age: embryonic day 12.5
Note: Expression was low in the roof of the forebrain.
Specimen Label: not shown E12
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5618255
Age: embryonic day 10.5
Note: Expression was dorsal.
Specimen Label: not shown E10
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5618255
Age: embryonic day 11.5
Note: Expression was dorsal.
Specimen Label: not shown E11
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1698920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5618255
Age: embryonic day 12.5
Specimen Label: not shown E12
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607313
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:5618255
Age: embryonic day 8.5
Note: Expression was detected in the neural tube when it was partially closed.
Specimen Label: not shown E8
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:5618255
Age: embryonic day 3.5
Specimen Label: not shown blastocyst
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1727220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5618255
Age: embryonic day 12.5
Note: Expression was noted around the heart and respiratory tract.
Specimen Label: 2D
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5618255
Age: embryonic day 12.5
Specimen Label: not shown E12
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616413
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:5618255
Age: embryonic day 8.5
Specimen Label: not shown E8
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5618255
Age: embryonic day 10.5
Specimen Label: not shown E10
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609513
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:5618255
Age: embryonic day 8.5
Specimen Label: not shown E8
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3292120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5618255
Age: embryonic day 12.5
Specimen Label: not shown E12
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Not Specified
Stage: TS02
Assay Id: MGI:5618255
Age: embryonic day 1.0
Specimen Label: not shown 2 cell
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5618255
Age: embryonic day 12.5
Specimen Label: 2D
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5617771
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5618255
Age: embryonic day 10.5
Specimen Label: not shown E10
Detected: true
Specimen Num: 4
Publication
First Author: Mócsai A
Year: 2002
Journal: Immunity
Title: Syk is required for integrin signaling in neutrophils.
Volume: 16
Issue: 4
Pages: 547-58
Publication
First Author: Lee JY
Year: 2005
Journal: Biochem Pharmacol
Title: The regulation of the expression of inducible nitric oxide synthase by Src-family tyrosine kinases mediated through MyD88-independent signaling pathways of Toll-like receptor 4.
Volume: 70
Issue: 8
Pages: 1231-40
Publication
First Author: Borneo J
Year: 2007
Journal: Exp Hematol
Title: Src family kinase-mediated negative regulation of hematopoietic stem cell mobilization involves both intrinsic and microenvironmental factors.
Volume: 35
Issue: 7
Pages: 1026-37
Publication  
First Author: Futosi K
Year: 2023
Journal: Front Pharmacol
Title: Analysis of intracellular tyrosine phosphorylation in circulating neutrophils as a rapid assay for the in vivo effect of oral tyrosine kinase inhibitors.
Volume: 14
Pages: 1056154
Publication
First Author: Majeed M
Year: 2001
Journal: J Leukoc Biol
Title: Role of Src kinases and Syk in Fcgamma receptor-mediated phagocytosis and phagosome-lysosome fusion.
Volume: 70
Issue: 5
Pages: 801-11
Publication
First Author: Mermel CH
Year: 2006
Journal: Blood
Title: Src family kinases are important negative regulators of G-CSF-dependent granulopoiesis.
Volume: 108
Issue: 8
Pages: 2562-8
Publication
First Author: Orschell CM
Year: 2008
Journal: Exp Hematol
Title: Deficiency of Src family kinases compromises the repopulating ability of hematopoietic stem cells.
Volume: 36
Issue: 5
Pages: 655-66
Publication
First Author: Pereira S
Year: 2001
Journal: J Immunol
Title: Resting murine neutrophils express functional alpha 4 integrins that signal through Src family kinases.
Volume: 166
Issue: 6
Pages: 4115-23
Publication
First Author: Fitzer-Attas CJ
Year: 2000
Journal: J Exp Med
Title: Fcgamma receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn.
Volume: 191
Issue: 4
Pages: 669-82
Publication
First Author: Stadtmann A
Year: 2013
Journal: J Exp Med
Title: The PSGL-1-L-selectin signaling complex regulates neutrophil adhesion under flow.
Volume: 210
Issue: 11
Pages: 2171-80
Publication  
First Author: Zaleskas VM
Year: 2006
Journal: PLoS One
Title: Molecular pathogenesis and therapy of polycythemia induced in mice by JAK2 V617F.
Volume: 1
Pages: e18
Publication
First Author: Nelson MP
Year: 2011
Journal: J Immunol
Title: IL-33 and M2a alveolar macrophages promote lung defense against the atypical fungal pathogen Pneumocystis murina.
Volume: 186
Issue: 4
Pages: 2372-81
Publication
First Author: Fumagalli L
Year: 2013
Journal: J Immunol
Title: Class I phosphoinositide-3-kinases and SRC kinases play a nonredundant role in regulation of adhesion-independent and -dependent neutrophil reactive oxygen species generation.
Volume: 190
Issue: 7
Pages: 3648-60
Publication
First Author: Kamen LA
Year: 2011
Journal: J Immunol
Title: Pyk2 is required for neutrophil degranulation and host defense responses to bacterial infection.
Volume: 186
Issue: 3
Pages: 1656-65