|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 374 for Fh1

<< First    < Previous  |  Next >    Last >>
0.038s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression  
Probe: MGI:3724701
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826253
Age: embryonic day 14.5
Image: Additional file 4 Fh1
Specimen Label: Additional file 4 Fh1
Detected: true
Specimen Num: 1
Publication
First Author: Pollard PJ
Year: 2007
Journal: Cancer Cell
Title: Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway.
Volume: 11
Issue: 4
Pages: 311-9
GO Term
Publication
First Author: Frezza C
Year: 2011
Journal: Nature
Title: Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
Volume: 477
Issue: 7363
Pages: 225-8
Publication  
First Author: Zheng L
Year: 2015
Journal: Nat Commun
Title: Fumarate induces redox-dependent senescence by modifying glutathione metabolism.
Volume: 6
Pages: 6001
Publication
First Author: Adam J
Year: 2013
Journal: Cell Rep
Title: A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia.
Volume: 3
Issue: 5
Pages: 1440-8
Publication
First Author: Guitart AV
Year: 2017
Journal: J Exp Med
Title: Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions.
Volume: 214
Issue: 3
Pages: 719-735
Publication
First Author: Adam J
Year: 2017
Journal: Cell Rep
Title: Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes.
Volume: 20
Issue: 13
Pages: 3135-3148
Publication
First Author: Ashrafian H
Year: 2012
Journal: Cell Metab
Title: Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway.
Volume: 15
Issue: 3
Pages: 361-71
Publication
First Author: Bardella C
Year: 2011
Journal: J Pathol
Title: Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status.
Volume: 225
Issue: 1
Pages: 4-11
Publication
First Author: Bardella C
Year: 2012
Journal: Mol Cell Biol
Title: Cells lacking the fumarase tumor suppressor are protected from apoptosis through a hypoxia-inducible factor-independent, AMPK-dependent mechanism.
Volume: 32
Issue: 15
Pages: 3081-94
Publication
First Author: Adam J
Year: 2011
Journal: Cancer Cell
Title: Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling.
Volume: 20
Issue: 4
Pages: 524-37
Publication  
First Author: Lepoutre-Lussey C
Year: 2016
Journal: Mol Cell Endocrinol
Title: From Nf1 to Sdhb knockout: Successes and failures in the quest for animal models of pheochromocytoma.
Volume: 421
Pages: 40-8
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Fu X
Year: 1997
Journal: Mol Cell Biol
Title: E2a-Pbx1 induces aberrant expression of tissue-specific and developmentally regulated genes when expressed in NIH 3T3 fibroblasts.
Volume: 17
Issue: 3
Pages: 1503-12
Publication
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Bochkis IM
Year: 2012
Journal: PLoS Genet
Title: Genome-wide location analysis reveals distinct transcriptional circuitry by paralogous regulators Foxa1 and Foxa2.
Volume: 8
Issue: 6
Pages: e1002770
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication    
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
Publication
First Author: Knudsen JG
Year: 2019
Journal: Cell Metab
Title: Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production.
Volume: 29
Issue: 2
Pages: 430-442.e4
Publication
First Author: Bulusu V
Year: 2017
Journal: Dev Cell
Title: Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Volume: 40
Issue: 4
Pages: 331-341.e4
Publication
First Author: Yang H
Year: 2016
Journal: Diabetes
Title: Adipose-Specific Deficiency of Fumarate Hydratase in Mice Protects Against Obesity, Hepatic Steatosis, and Insulin Resistance.
Volume: 65
Issue: 11
Pages: 3396-3409
Publication
First Author: Mayeuf-Louchart A
Year: 2019
Journal: Cell Rep
Title: Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation.
Volume: 29
Issue: 6
Pages: 1410-1418.e6
Publication
First Author: Wongkittichote P
Year: 2019
Journal: Mol Genet Metab
Title: Tricarboxylic acid cycle enzyme activities in a mouse model of methylmalonic aciduria.
Volume: 128
Issue: 4
Pages: 444-451
Publication
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication
First Author: O'Flaherty L
Year: 2010
Journal: Hum Mol Genet
Title: Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism.
Volume: 19
Issue: 19
Pages: 3844-51
Publication
First Author: Alam NA
Year: 2003
Journal: Hum Mol Genet
Title: Genetic and functional analyses of FH mutations in multiple cutaneous and uterine leiomyomatosis, hereditary leiomyomatosis and renal cancer, and fumarate hydratase deficiency.
Volume: 12
Issue: 11
Pages: 1241-52
Publication  
First Author: Cankaya M
Year: 2007
Journal: BMC Genomics
Title: An analysis of expression patterns of genes encoding proteins with catalytic activities.
Volume: 8
Pages: 232
Publication
First Author: Stylianou IM
Year: 2008
Journal: Genetics
Title: Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification.
Volume: 178
Issue: 3
Pages: 1795-805
Publication
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
Publication
First Author: Du JX
Year: 2008
Journal: J Biol Chem
Title: SUMOylation regulates nuclear localization of Krüppel-like factor 5.
Volume: 283
Issue: 46
Pages: 31991-2002
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication
First Author: Xiao M
Year: 2012
Journal: Genes Dev
Title: Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors.
Volume: 26
Issue: 12
Pages: 1326-38
Publication
First Author: Bowman CE
Year: 2016
Journal: Mol Cell Biol
Title: Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Volume: 36
Issue: 15
Pages: 2089-104
Publication
First Author: Sciacovelli M
Year: 2016
Journal: Nature
Title: Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition.
Volume: 537
Issue: 7621
Pages: 544-547
GXD Expression      
Probe: MGI:1289509
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2662834
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1289509
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2662834
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1289509
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2662834
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1289509
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2662834
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1289509
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2662834
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:1289509
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2662834
Age: postnatal adult
Specimen Label: Skeletal m.
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:1289509
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2662834
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:1289509
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2662834
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:1289509
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2662852
Age: embryonic day 7.0
Specimen Label: 7
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1289509
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2662852
Age: embryonic day 11.0
Specimen Label: 11
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1289509
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2662852
Age: embryonic day 15.0
Specimen Label: 15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1289509
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2662852
Age: embryonic day 17.0
Specimen Label: 17
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3826375
Assay Type: RT-PCR
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706619
Stage: TS19
Assay Id: MGI:3826449
Age: embryonic day 11.5
Image: 4
Specimen Label: TS19
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3826375
Assay Type: RT-PCR
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750321
Stage: TS21
Assay Id: MGI:3826449
Age: embryonic day 13.5
Image: 4
Specimen Label: TS21
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3826375
Assay Type: RT-PCR
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750323
Stage: TS23
Assay Id: MGI:3826449
Age: embryonic day 15.5
Image: 4
Specimen Label: TS23
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3826375
Assay Type: RT-PCR
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:3826449
Age: embryonic day 18.5
Image: 4
Specimen Label: TS26
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3826375
Assay Type: RT-PCR
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3295228
Stage: TS28
Assay Id: MGI:3826449
Age: postnatal adult
Image: 4
Specimen Label: Ducts
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3826375
Assay Type: RT-PCR
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Stage: TS28
Assay Id: MGI:3826449
Age: postnatal adult
Image: 4
Specimen Label: Islets
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7547452
Assay Type: RT-PCR
Annotation Date: 2023-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920922
Stage: TS22
Assay Id: MGI:7547501
Age: embryonic day 14.5
Image: S4
Specimen Label: E14.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7547452
Assay Type: RT-PCR
Annotation Date: 2023-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920923
Stage: TS23
Assay Id: MGI:7547501
Age: embryonic day 15.5
Image: S4
Specimen Label: E15.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7547452
Assay Type: RT-PCR
Annotation Date: 2023-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920924
Stage: TS24
Assay Id: MGI:7547501
Age: embryonic day 16.5
Image: S4
Specimen Label: E16.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7547452
Assay Type: RT-PCR
Annotation Date: 2023-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920925
Stage: TS25
Assay Id: MGI:7547501
Age: embryonic day 17.5
Image: S4
Specimen Label: E17.5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7547452
Assay Type: RT-PCR
Annotation Date: 2023-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920926
Stage: TS26
Assay Id: MGI:7547501
Age: embryonic day 18.5
Image: S4
Specimen Label: E18.5
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3724701
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3516422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421360
Age: embryonic day 14.5
Image: MH954; Specimen C1363
Specimen Label: MH954; Specimen C1363
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724701
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421360
Age: embryonic day 14.5
Image: MH954; Specimen C1363
Specimen Label: MH954; Specimen C1363
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724701
Assay Type: RNA in situ
Annotation Date: 2008-02-05
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3769877
Age: embryonic day 14.5
Image: 3B
Specimen Label: 3B
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724701
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421360
Age: embryonic day 14.5
Image: MH954; Specimen C1363
Specimen Label: MH954; Specimen C1363
Detected: true
Specimen Num: 1