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Search results 1 to 100 out of 121 for Fis1

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2.296s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Saccharomyces cerevisiae
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: Fis1 is an outer mitochondrial membrane protein that plays a role in mitochondrial membrane fission []. In Saccharomyces cerevisiae, it facilitates mitochondrial fission by forming protein complexes with Dnm1 and Mdv1 []. It contains tetratrico-peptide repeat (TPR)-like domain and a C-terminal transmembrane region [, ].
Publication
First Author: Suzuki M
Year: 2003
Journal: J Mol Biol
Title: The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle.
Volume: 334
Issue: 3
Pages: 445-58
Publication
First Author: Dohm JA
Year: 2004
Journal: Proteins
Title: Cytosolic domain of the human mitochondrial fission protein fis1 adopts a TPR fold.
Volume: 54
Issue: 1
Pages: 153-6
Publication
First Author: Stojanovski D
Year: 2004
Journal: J Cell Sci
Title: Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology.
Volume: 117
Issue: Pt 7
Pages: 1201-10
Protein
Organism: Mus musculus
Length: 152  
Fragment?: false
Publication
First Author: Mozdy AD
Year: 2000
Journal: J Cell Biol
Title: Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p.
Volume: 151
Issue: 2
Pages: 367-80
Publication
First Author: Kuravi K
Year: 2006
Journal: J Cell Sci
Title: Dynamin-related proteins Vps1p and Dnm1p control peroxisome abundance in Saccharomyces cerevisiae.
Volume: 119
Issue: Pt 19
Pages: 3994-4001
Protein
Organism: Mus musculus
Length: 145  
Fragment?: false
Protein
Organism: Mus musculus
Length: 102  
Fragment?: false
Publication
First Author: Kobayashi S
Year: 2007
Journal: Exp Cell Res
Title: Fis1, DLP1, and Pex11p coordinately regulate peroxisome morphogenesis.
Volume: 313
Issue: 8
Pages: 1675-86
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:5817597
Assay Type: Western blot
Annotation Date: 2017-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5817613
Age: postnatal adult
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5817597
Assay Type: Western blot
Annotation Date: 2017-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5817613
Age: postnatal adult
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5817597
Assay Type: Western blot
Annotation Date: 2017-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5817613
Age: postnatal adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5817597
Assay Type: Western blot
Annotation Date: 2017-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5817613
Age: postnatal adult
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5817597
Assay Type: Western blot
Annotation Date: 2017-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5817613
Age: postnatal adult
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5817597
Assay Type: Western blot
Annotation Date: 2017-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5817613
Age: postnatal adult
Detected: true
Specimen Num: 1
Publication  
First Author: Wang K
Year: 2012
Journal: Nat Commun
Title: miR-484 regulates mitochondrial network through targeting Fis1.
Volume: 3
Pages: 781
Publication
First Author: Otera H
Year: 2010
Journal: J Cell Biol
Title: Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells.
Volume: 191
Issue: 6
Pages: 1141-58
Publication
First Author: Ganapathy PS
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Homocysteine-mediated modulation of mitochondrial dynamics in retinal ganglion cells.
Volume: 52
Issue: 8
Pages: 5551-8
Publication
First Author: Losón OC
Year: 2013
Journal: Mol Biol Cell
Title: Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission.
Volume: 24
Issue: 5
Pages: 659-67
Publication
First Author: Niu J
Year: 2012
Journal: J Neurochem
Title: Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein.
Volume: 122
Issue: 3
Pages: 650-8
Publication
First Author: Karbowski M
Year: 2006
Journal: Nature
Title: Role of Bax and Bak in mitochondrial morphogenesis.
Volume: 443
Issue: 7112
Pages: 658-62
Publication
First Author: Ishihara N
Year: 2009
Journal: Nat Cell Biol
Title: Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice.
Volume: 11
Issue: 8
Pages: 958-66
Publication    
First Author: Rojansky R
Year: 2016
Journal: Elife
Title: Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1.
Volume: 5
Publication
First Author: Moriya M
Year: 2015
Journal: Hum Mol Genet
Title: Adult mice expressing a Braf Q241R mutation on an ICR/CD-1 background exhibit a cardio-facio-cutaneous syndrome phenotype.
Volume: 24
Issue: 25
Pages: 7349-60
Publication
First Author: Kikuchi M
Year: 2004
Journal: J Biol Chem
Title: Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease.
Volume: 279
Issue: 1
Pages: 421-8
Publication
First Author: Ishihara T
Year: 2015
Journal: Mol Cell Biol
Title: Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development.
Volume: 35
Issue: 1
Pages: 211-23
Publication
First Author: Gómez-Del Arco P
Year: 2016
Journal: Cell Metab
Title: The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis.
Volume: 23
Issue: 5
Pages: 881-92
Publication
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
Publication
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics, the Protein Information Resource and the Protein Ontology Consortium
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication
First Author: Suzuki M
Year: 2005
Journal: J Biol Chem
Title: Novel structure of the N terminus in yeast Fis1 correlates with a specialized function in mitochondrial fission.
Volume: 280
Issue: 22
Pages: 21444-52
Other Genome Feature
Type: sequence_feature
Organism: Mus musculus
Publication
First Author: Iwasawa R
Year: 2011
Journal: EMBO J
Title: Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction.
Volume: 30
Issue: 3
Pages: 556-68
Protein Domain
Type: Repeat
Description: The mitochondrial fission protein Fis1 consists of two tetratricopeptide repeats. This entry represents the N-terminal tetratricopeptide repeat [, ]. Fis1 is an outer mitochondrial membrane protein that plays a role in mitochondrial membrane fission [].
Protein Domain
Type: Repeat
Description: The mitochondrial fission protein Fis1 consists of two tetratricopeptide repeats. This entry represents the C-terminal tetratricopeptide repeat [, ]. Fis1 is an outer mitochondrial membrane protein that plays a role in mitochondrial membrane fission [].
Publication
First Author: Palmer CS
Year: 2013
Journal: J Biol Chem
Title: Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission.
Volume: 288
Issue: 38
Pages: 27584-93
Publication
First Author: Zhang Y
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Structural basis for recruitment of mitochondrial fission complexes by Fis1.
Volume: 104
Issue: 47
Pages: 18526-30
Publication  
First Author: Hoppins S
Year: 2007
Journal: Annu Rev Biochem
Title: The machines that divide and fuse mitochondria.
Volume: 76
Pages: 751-80
Publication
First Author: Guo Q
Year: 2012
Journal: PLoS One
Title: The mitochondrial fission adaptors Caf4 and Mdv1 are not functionally equivalent.
Volume: 7
Issue: 12
Pages: e53523
Protein Domain
Type: Domain
Description: Fis1, along with Dnm1 and Mdv1, is an essential protein in mediating mitochondrial fission. Dnm1 and Fis1 are highly conserved, with a common mechanism in disparate species. In mutants of these proteins, mitochondrial fission is impaired, resulting in networks of undivided mitochondria. Fis1 appears to act via the recruitment of division complexes to the mitochondrial outer membrane. Dnm1 is recruited to mitochondria via interactions with the adaptor proteins Caf4 and Mdv1, which bind directly to Fis1 [, ].The Fis1 N terminus is cytosolic and tethered to the mitochondrial outer membrane via a C-terminal transmembrane domain. The cytosolic domain of Fis1 forms a six-helix bundle, in which the central four helices consist of two tandem tetratricopeptide repeat (TPR)-like motifs, known to mediate protein-protein interactions [, , , ].
Publication
First Author: Liu HY
Year: 2001
Journal: J Biol Chem
Title: Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme.
Volume: 276
Issue: 10
Pages: 7541-8
Publication
First Author: Schauss AC
Year: 2006
Journal: J Cell Sci
Title: Fis1p and Caf4p, but not Mdv1p, determine the polar localization of Dnm1p clusters on the mitochondrial surface.
Volume: 119
Issue: Pt 15
Pages: 3098-106
Protein Domain
Type: Family
Description: Caf4 is a WD40 repeats containing protein involved in mitochondrial fission. It displays physical interactions with CCR4-NOT complex []. It has a paralogue, Mdv1. Both Caf4 and Mdv1 act as adapter proteins, binding to Fis1 on the mitochondrial outer membrane and recruiting the dynamin-like GTPase Dnm1 to form mitochondrial fission complexes []. However, Fis1 and Caf4, but not Mdv1, determine the polar localization of Dnm1 clusters on the mitochondrial surface [].