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Search results 1 to 100 out of 118 for Fkbp4

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
2288 | FKBP4
Type: gene
Organism: human
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Gene
508535 | FKBP4
Type: gene
Organism: cattle
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Gene
418261 | FKBP4
Type: gene
Organism: chicken
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Gene
321795 | fkbp4
Type: gene
Organism: zebrafish
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Gene
708481 | FKBP4
Type: gene
Organism: macaque, rhesus
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Gene
100379681 | fkbp4
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR031212 | FKBP4
Type: Family
Description: FKBP4 (also known as FKBP52) is an immunophilin that binds immunosuppressive drugs such as FK506 []. It interacts with Hsp90 []and has been shown to have peptidyl prolyl cis/trans isomerase activity []. It controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening [].
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Gene
260321 | Fkbp4
Type: gene
Organism: rat
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Gene
477726 | FKBP4
Type: gene
Organism: dog, domestic
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Gene
451748 | FKBP4
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:95543 | Fkbp4
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
19945390 | J:155746
First Author: Shim S
Year: 2009
Journal: Neuron
Title: Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening.
Volume: 64
Issue: 4
Pages: 471-83
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GXD Expression
GXD Expression
 
Probe: MGI:1031942
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825689
Age: embryonic day 14.5
Image: Additional file 4 Fkbp4
Specimen Label: Additional file 4 Fkbp4
Detected: true
Specimen Num: 1
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Protein
P30416
Organism: Mus musculus/domesticus
Length: 458  
Fragment?: false
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Publication
20188096 | -
First Author: Shimamoto S
Year: 2010
Journal: FEBS Lett
Title: S100 proteins regulate the interaction of Hsp90 with Cyclophilin 40 and FKBP52 through their tetratricopeptide repeats.
Volume: 584
Issue: 6
Pages: 1119-25
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Publication
11350175 | -
First Author: Pirkl F
Year: 2001
Journal: J Mol Biol
Title: Functional analysis of the Hsp90-associated human peptidyl prolyl cis/trans isomerases FKBP51, FKBP52 and Cyp40.
Volume: 308
Issue: 4
Pages: 795-806
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Publication
18635947 | -
First Author: Kang CB
Year: 2008
Journal: Neurosignals
Title: FKBP family proteins: immunophilins with versatile biological functions.
Volume: 16
Issue: 4
Pages: 318-25
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Protein
F7CAT1
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
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Publication
7693550 | J:15654
First Author: Schmitt J
Year: 1993
Journal: Gene
Title: Cloning and expression of a mouse cDNA encoding p59, an immunophilin that associates with the glucocorticoid receptor.
Volume: 132
Issue: 2
Pages: 267-71
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Publication
8341706 | J:13203
First Author: Alnemri ES
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Overexpression, characterization, and purification of a recombinant mouse immunophilin FKBP-52 and identification of an associated phosphoprotein.
Volume: 90
Issue: 14
Pages: 6839-43
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Protein
F6S2D5
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: true
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Publication
11751894 | J:74637
First Author: Davies TH
Year: 2002
Journal: J Biol Chem
Title: A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins.
Volume: 277
Issue: 7
Pages: 4597-600
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Publication
30485818 | J:271066
First Author: Ruiz-Estevez M
Year: 2018
Journal: Cell Rep
Title: Promotion of Myoblast Differentiation by Fkbp5 via Cdk4 Isomerization.
Volume: 25
Issue: 9
Pages: 2537-2551.e8
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Protein Coding Gene
MGP_CAROLIEiJ_G0028910 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031327 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031298 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031226 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031305 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031029 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_95543 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031764 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030410 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030990 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031146 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031096 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031226 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031134 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031797 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030125 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030495 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022674 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029954 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16873445 | J:114715
First Author: Yang Z
Year: 2006
Journal: Mol Endocrinol
Title: FK506-binding protein 52 is essential to uterine reproductive physiology controlled by the progesterone receptor A isoform.
Volume: 20
Issue: 11
Pages: 2682-94
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Publication
15831525 | J:98554
First Author: Cheung-Flynn J
Year: 2005
Journal: Mol Endocrinol
Title: Physiological role for the cochaperone FKBP52 in androgen receptor signaling.
Volume: 19
Issue: 6
Pages: 1654-66
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Publication
17571166 | J:124192
First Author: Tranguch S
Year: 2007
Journal: J Clin Invest
Title: FKBP52 deficiency-conferred uterine progesterone resistance is genetic background and pregnancy stage specific.
Volume: 117
Issue: 7
Pages: 1824-34
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Publication
23999428 | J:203921
First Author: Blair LJ
Year: 2013
Journal: J Clin Invest
Title: Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.
Volume: 123
Issue: 10
Pages: 4158-69
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Publication
24850415 | J:215240
First Author: Haraguchi H
Year: 2014
Journal: Mol Endocrinol
Title: MicroRNA-200a locally attenuates progesterone signaling in the cervix, preventing embryo implantation.
Volume: 28
Issue: 7
Pages: 1108-17
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Publication
17307907 | J:118360
First Author: Hong J
Year: 2007
Journal: Reproduction
Title: Deficiency of co-chaperone immunophilin FKBP52 compromises sperm fertilizing capacity.
Volume: 133
Issue: 2
Pages: 395-403
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Publication
11514552 | J:72179
First Author: Goel M
Year: 2001
Journal: J Biol Chem
Title: Regulation of Drosophila TRPL channels by immunophilin FKBP59.
Volume: 276
Issue: 42
Pages: 38762-73
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Publication
22641006 | J:318091
First Author: Hartmann J
Year: 2012
Journal: Psychoneuroendocrinology
Title: Fkbp52 heterozygosity alters behavioral, endocrine and neurogenetic parameters under basal and chronic stress conditions in mice.
Volume: 37
Issue: 12
Pages: 2009-21
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GXD Expression
GXD Expression
Probe: MGI:7496023
Assay Type: RNA in situ
Annotation Date: 2023-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:1898926
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7496026
Age: embryonic day 18.5
Image: 1a
Note: Expression in preputial epithelium.
Specimen Label: 1a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7496023
Assay Type: RNA in situ
Annotation Date: 2023-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:2916726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7496026
Age: embryonic day 18.5
Image: 1a
Note: Expression in genital mesenchyme.
Specimen Label: 1a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7496023
Assay Type: RNA in situ
Annotation Date: 2023-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:3094626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7496026
Age: embryonic day 18.5
Image: 1a
Note: Highest expression in ventral aspect of urethral epithelium compared with dorsal aspect. In unfused urethra, clear border separating high expressing cells from low expressing cells.
Specimen Label: 1a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7496023
Assay Type: RNA in situ
Annotation Date: 2023-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:3094626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7496026
Age: embryonic day 18.5
Image: 1b
Note: In fused urethra, expression also highest in ventral aspect compared to dorsal aspect.
Specimen Label: 1b
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7496023
Assay Type: RNA in situ
Annotation Date: 2023-07-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1868226
Stage: TS26
Assay Id: MGI:7496026
Age: embryonic day 18.5
Image: 1c
Specimen Label: 1c
Detected: false
Specimen Num: 3
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Publication
21935478 | J:177683
First Author: O'Leary JC 3rd
Year: 2011
Journal: PLoS One
Title: A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51.
Volume: 6
Issue: 9
Pages: e24840
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Publication
20796173 | J:165858
First Author: Quintá HR
Year: 2010
Journal: J Neurochem
Title: Subcellular rearrangement of hsp90-binding immunophilins accompanies neuronal differentiation and neurite outgrowth.
Volume: 115
Issue: 3
Pages: 716-34
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Gene
106998474 | LOC106998474
Type: gene
Organism: macaque, rhesus
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Publication
18988805 | J:141411
First Author: Hirota Y
Year: 2008
Journal: Am J Pathol
Title: Deficiency of immunophilin FKBP52 promotes endometriosis.
Volume: 173
Issue: 6
Pages: 1747-57
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Publication
2592022 | J:10145
First Author: Kuhner MK
Year: 1989
Journal: Immunogenetics
Title: DNA sequences of mouse H-2 and Qa genes.
Volume: 30
Issue: 6
Pages: 458-64
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Publication
20038533 | J:161739
First Author: Galigniana MD
Year: 2010
Journal: Mol Cell Biol
Title: The hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear events.
Volume: 30
Issue: 5
Pages: 1285-98
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Publication
7493967 | J:30020
First Author: Coss MC
Year: 1995
Journal: J Biol Chem
Title: Molecular cloning, DNA sequence analysis, and biochemical characterization of a novel 65-kDa FK506-binding protein (FKBP65).
Volume: 270
Issue: 49
Pages: 29336-41
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Publication
17142810 | J:120960
First Author: Yong W
Year: 2007
Journal: J Biol Chem
Title: Essential role for Co-chaperone Fkbp52 but not Fkbp51 in androgen receptor-mediated signaling and physiology.
Volume: 282
Issue: 7
Pages: 5026-36
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Publication
20713718 | J:163744
First Author: Hirota Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Uterine FK506-binding protein 52 (FKBP52)-peroxiredoxin-6 (PRDX6) signaling protects pregnancy from overt oxidative stress.
Volume: 107
Issue: 35
Pages: 15577-82
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Publication
22416080 | J:184984
First Author: Hirota Y
Year: 2012
Journal: Endocrinology
Title: Galectin-1 markedly reduces the incidence of resorptions in mice missing immunophilin FKBP52.
Volume: 153
Issue: 5
Pages: 2486-93
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Publication
20605780 | J:166178
First Author: Chen H
Year: 2010
Journal: J Biol Chem
Title: Fkbp52 regulates androgen receptor transactivation activity and male urethra morphogenesis.
Volume: 285
Issue: 36
Pages: 27776-84
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Publication
16176985 | J:101405
First Author: Tranguch S
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Cochaperone immunophilin FKBP52 is critical to uterine receptivity for embryo implantation.
Volume: 102
Issue: 40
Pages: 14326-31
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Publication
19581287 | J:152609
First Author: Echeverría PC
Year: 2009
Journal: Mol Cell Biol
Title: Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta.
Volume: 29
Issue: 17
Pages: 4788-97
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Publication
24880616 | J:226885
First Author: Tannour-Louet M
Year: 2014
Journal: Nat Med
Title: Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action.
Volume: 20
Issue: 7
Pages: 715-24
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Publication
23676498 | J:201437
First Author: Nagashima T
Year: 2013
Journal: J Clin Invest
Title: BMPR2 is required for postimplantation uterine function and pregnancy maintenance.
Volume: 123
Issue: 6
Pages: 2539-50
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Publication
26184908 | J:258557
First Author: Tu Z
Year: 2016
Journal: Cell Death Differ
Title: Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice.
Volume: 23
Issue: 1
Pages: 169-81
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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