|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 232 for Flcn

<< First    < Previous  |  Next >    Last >>
0.039s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Kennedy JC
Year: 2019
Journal: Hum Mol Genet
Title: Loss of FLCN inhibits canonical WNT signaling via TFE3.
Volume: 28
Issue: 19
Pages: 3270-3281
Publication
First Author: Isono Y
Year: 2020
Journal: Biochem Biophys Res Commun
Title: FLCN alteration drives metabolic reprogramming towards nucleotide synthesis and cyst formation in salivary gland.
Volume: 522
Issue: 4
Pages: 931-938
Publication
First Author: Yan M
Year: 2016
Journal: Genes Dev
Title: Chronic AMPK activation via loss of FLCN induces functional beige adipose tissue through PGC-1α/ERRα.
Volume: 30
Issue: 9
Pages: 1034-46
Publication
First Author: Chen J
Year: 2015
Journal: Kidney Int
Title: Disruption of tubular Flcn expression as a mouse model for renal tumor induction.
Volume: 88
Issue: 5
Pages: 1057-69
Publication
First Author: Possik E
Year: 2015
Journal: PLoS Genet
Title: FLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen Stores.
Volume: 11
Issue: 10
Pages: e1005520
Publication
First Author: Wada S
Year: 2016
Journal: Genes Dev
Title: The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue.
Volume: 30
Issue: 22
Pages: 2551-2564
Publication
First Author: Hong SB
Year: 2010
Journal: PLoS One
Title: Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization.
Volume: 5
Issue: 12
Pages: e15793
Publication
First Author: Tai-Nagara I
Year: 2020
Journal: Nat Commun
Title: Blood and lymphatic systems are segregated by the FLCN tumor suppressor.
Volume: 11
Issue: 1
Pages: 6314
Publication
First Author: Chen J
Year: 2008
Journal: PLoS One
Title: Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia.
Volume: 3
Issue: 10
Pages: e3581
Publication
First Author: Paquette M
Year: 2021
Journal: Sci Rep
Title: Loss of hepatic Flcn protects against fibrosis and inflammation by activating autophagy pathways.
Volume: 11
Issue: 1
Pages: 21268
Publication
First Author: El-Houjeiri L
Year: 2019
Journal: Cell Rep
Title: The Transcription Factors TFEB and TFE3 Link the FLCN-AMPK Signaling Axis to Innate Immune Response and Pathogen Resistance.
Volume: 26
Issue: 13
Pages: 3613-3628.e6
Publication
First Author: Goncharova EA
Year: 2014
Journal: Cell Rep
Title: Folliculin controls lung alveolar enlargement and epithelial cell survival through E-cadherin, LKB1, and AMPK.
Volume: 7
Issue: 2
Pages: 412-23
Publication  
First Author: Laviolette LA
Year: 2017
Journal: Nat Commun
Title: Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein.
Volume: 8
Pages: 15866
Publication
First Author: Endoh M
Year: 2020
Journal: Cell Rep
Title: A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity.
Volume: 30
Issue: 6
Pages: 1823-1834.e5
Publication
First Author: Wu M
Year: 2015
Journal: Oncotarget
Title: Flcn-deficient renal cells are tumorigenic and sensitive to mTOR suppression.
Volume: 6
Issue: 32
Pages: 32761-73
Publication
First Author: Petit CS
Year: 2013
Journal: J Cell Biol
Title: Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases.
Volume: 202
Issue: 7
Pages: 1107-22
Publication
First Author: Hasumi H
Year: 2017
Journal: Hum Mol Genet
Title: H255Y and K508R missense mutations in tumour suppressor folliculin (FLCN) promote kidney cell proliferation.
Volume: 26
Issue: 2
Pages: 354-366
Publication
First Author: Yan M
Year: 2014
Journal: J Clin Invest
Title: The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation.
Volume: 124
Issue: 6
Pages: 2640-50
Protein
Organism: Mus musculus/domesticus
Length: 43  
Fragment?: true
Publication    
First Author: Li J
Year: 2019
Journal: JCI Insight
Title: Myeloid Folliculin balances mTOR activation to maintain innate immunity homeostasis.
Volume: 5
Publication
First Author: Medvetz DA
Year: 2012
Journal: PLoS One
Title: Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion.
Volume: 7
Issue: 11
Pages: e47842
Publication
First Author: Nahorski MS
Year: 2012
Journal: Hum Mol Genet
Title: Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis.
Volume: 21
Issue: 24
Pages: 5268-79
Publication
First Author: Betschinger J
Year: 2013
Journal: Cell
Title: Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3.
Volume: 153
Issue: 2
Pages: 335-47
Publication
First Author: Hasumi Y
Year: 2014
Journal: Hum Mol Genet
Title: Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation.
Volume: 23
Issue: 21
Pages: 5706-19
Publication
First Author: Baba M
Year: 2016
Journal: Stem Cells
Title: Loss of Folliculin Disrupts Hematopoietic Stem Cell Quiescence and Homeostasis Resulting in Bone Marrow Failure.
Volume: 34
Issue: 4
Pages: 1068-82
Publication
First Author: Baba M
Year: 2012
Journal: Blood
Title: The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development.
Volume: 120
Issue: 6
Pages: 1254-61
Publication
First Author: Hasumi H
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn.
Volume: 112
Issue: 13
Pages: E1624-31
Publication
First Author: Zhou Q
Year: 2017
Journal: Biochim Biophys Acta
Title: Dihydromyricetin prevents obesity-induced slow-twitch-fiber reduction partially via FLCN/FNIP1/AMPK pathway.
Volume: 1863
Issue: 6
Pages: 1282-1291
Publication
First Author: Di Malta C
Year: 2023
Journal: EMBO Mol Med
Title: TFEB and TFE3 drive kidney cystogenesis and tumorigenesis.
Volume: 15
Issue: 5
Pages: e16877
Publication
First Author: Hasumi H
Year: 2012
Journal: J Natl Cancer Inst
Title: Regulation of mitochondrial oxidative metabolism by tumor suppressor FLCN.
Volume: 104
Issue: 22
Pages: 1750-64
Publication
First Author: Guo C
Year: 2023
Journal: Nature
Title: SLC38A2 and glutamine signalling in cDC1s dictate anti-tumour immunity.
Volume: 620
Issue: 7972
Pages: 200-208
Publication
First Author: Hudon V
Year: 2010
Journal: J Med Genet
Title: Renal tumour suppressor function of the Birt-Hogg-Dubé syndrome gene product folliculin.
Volume: 47
Issue: 3
Pages: 182-9
Publication
First Author: Zhang X
Year: 2023
Journal: Nature
Title: Reprogramming tumour-associated macrophages to outcompete cancer cells.
Volume: 619
Issue: 7970
Pages: 616-623
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Cash TP
Year: 2011
Journal: Oncogene
Title: Loss of the Birt-Hogg-Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription.
Volume: 30
Issue: 22
Pages: 2534-46
Publication
First Author: Hartman TR
Year: 2009
Journal: Oncogene
Title: The role of the Birt-Hogg-Dubé protein in mTOR activation and renal tumorigenesis.
Volume: 28
Issue: 13
Pages: 1594-604
GXD Expression    
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:5304192
Age: embryonic day 8.5
Image: S1
Specimen Label: e8.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5304192
Age: embryonic day 9.5
Image: S1
Specimen Label: e9.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:5304192
Age: embryonic day 12.5
Image: S1
Specimen Label: e12.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:5304192
Age: embryonic day 19.0
Image: S1
Specimen Label: e19
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Brain
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Heart
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Kidney
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Spleen
Specimen Num: 8
GXD Expression      
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Thymus
Specimen Num: 9
GXD Expression    
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Liver
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Stomach
Specimen Num: 11
GXD Expression      
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Sm. Intestine
Specimen Num: 12
GXD Expression      
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Muscle
Specimen Num: 13
GXD Expression    
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Lung
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Testis
Specimen Num: 15
GXD Expression      
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Skin
Specimen Num: 16
GXD Expression    
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Adrenal Gland
Detected: true
Specimen Num: 17
GXD Expression    
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Pancreas
Detected: true
Specimen Num: 18
GXD Expression    
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Uterus
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1928728
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Prostate Gland
Detected: true
Specimen Num: 20
GXD Expression    
Probe: MGI:5303061
Assay Type: RT-PCR
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:5304192
Age: postnatal
Image: S1
Specimen Label: Breast/Virgin
Detected: true
Specimen Num: 21
GXD Expression    
Probe: MGI:5303081
Assay Type: Western blot
Annotation Date: 2012-01-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5304302
Age: postnatal
Image: 3
Specimen Label: Normal kidney1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5303081
Assay Type: Western blot
Annotation Date: 2012-01-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5304302
Age: postnatal
Image: 3
Specimen Label: Normal kidney2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5303081
Assay Type: Western blot
Annotation Date: 2012-01-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5304302
Age: postnatal
Image: 3
Specimen Label: Normal kidney3
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5303081
Assay Type: Western blot
Annotation Date: 2012-01-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5304302
Age: postnatal
Image: 3
Specimen Label: Normal kidney4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5303083
Assay Type: Western blot
Annotation Date: 2012-01-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5304311
Age: postnatal
Specimen Label: Not shown
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5303081
Assay Type: Western blot
Annotation Date: 2012-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5304565
Age: postnatal
Image: 5
Specimen Label: Normal1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5303081
Assay Type: Western blot
Annotation Date: 2012-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5304565
Age: postnatal
Image: 5
Specimen Label: Normal2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5303081
Assay Type: Western blot
Annotation Date: 2012-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5304565
Age: postnatal
Image: 5
Specimen Label: Normal3
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5303081
Assay Type: Western blot
Annotation Date: 2012-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5304565
Age: postnatal
Image: 5
Specimen Label: Normal4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7334778
Assay Type: Northern blot
Annotation Date: 2022-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:7334800
Age: embryonic day 12.5
Specimen Label: E12.5 +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7334778
Assay Type: Northern blot
Annotation Date: 2022-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:7334800
Age: embryonic day 12.5
Specimen Label: E12.5 +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7334778
Assay Type: Northern blot
Annotation Date: 2022-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7334800
Age: postnatal adult
Specimen Label: Kidney +/+
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7334778
Assay Type: Northern blot
Annotation Date: 2022-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7334800
Age: postnatal adult
Specimen Label: Kidney +/-
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7334779
Assay Type: RT-PCR
Annotation Date: 2022-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:7334801
Age: embryonic day 12.5
Specimen Label: E12.5 +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7334779
Assay Type: RT-PCR
Annotation Date: 2022-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:7334801
Age: embryonic day 12.5
Specimen Label: E12.5 +/-
Detected: true
Specimen Num: 2