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Search results 1 to 100 out of 724 for Flt4

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Type Details Score
Gene
2324 | FLT4
Type: gene
Organism: human
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Gene
338031 | FLT4
Type: gene
Organism: cattle
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Gene
395742 | FLT4
Type: gene
Organism: chicken
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Gene
30121 | flt4
Type: gene
Organism: zebrafish
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Gene
716412 | FLT4
Type: gene
Organism: macaque, rhesus
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Gene
100493801 | flt4
Type: gene
Organism: frog, western clawed
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Gene
114110 | Flt4
Type: gene
Organism: rat
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Gene
481464 | FLT4
Type: gene
Organism: dog, domestic
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Gene
462339 | FLT4
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:95561 | Flt4
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
9247316 | J:46616
First Author: Fitz LJ
Year: 1997
Journal: Oncogene
Title: Characterization of murine Flt4 ligand/VEGF-C.
Volume: 15
Issue: 5
Pages: 613-8
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GXD Expression
GXD Expression
   
Probe: MGI:1929295
Assay Type: RT-PCR
Annotation Date: 2001-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:1929452
Age: embryonic day 8.5
Image: 6
Specimen Label: +/- Flt4
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1929295
Assay Type: RT-PCR
Annotation Date: 2001-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:1929452
Age: embryonic day 8.5
Image: 6
Specimen Label: -/- Flt4
Detected: true
Specimen Num: 2
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Publication
7675451 | J:28962
First Author: Fournier E
Year: 1995
Journal: Oncogene
Title: Mutation at tyrosine residue 1337 abrogates ligand-dependent transforming capacity of the FLT4 receptor.
Volume: 11
Issue: 5
Pages: 921-31
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Publication
8386825 | J:4693
First Author: Galland F
Year: 1993
Journal: Oncogene
Title: The FLT4 gene encodes a transmembrane tyrosine kinase related to the vascular endothelial growth factor receptor.
Volume: 8
Issue: 5
Pages: 1233-40
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Publication
7687867 | J:12751
First Author: Armstrong E
Year: 1993
Journal: Genes Chromosomes Cancer
Title: FLT4 receptor tyrosine kinase gene mapping to chromosome band 5q35 in relation to the t(2;5), t(5;6), and t(3;5) translocations.
Volume: 7
Issue: 3
Pages: 144-51
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GXD Expression
GXD Expression
     
Probe: MGI:6172982
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190290
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Flt4
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6172982
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190290
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Flt4
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6172982
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190290
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Flt4
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6172982
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190290
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Flt4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6172982
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190290
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Flt4
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6172982
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190290
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Flt4
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6172982
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190290
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Flt4
Detected: true
Specimen Num: 7
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Publication
27942023 | J:254197
First Author: Huang JJ
Year: 2016
Journal: PLoS One
Title: Lymph Node Transplantation Decreases Swelling and Restores Immune Responses in a Transgenic Model of Lymphedema.
Volume: 11
Issue: 12
Pages: e0168259
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Publication
24469165 | J:264669
First Author: Aschen SZ
Year: 2014
Journal: Plast Reconstr Surg
Title: Lymph node transplantation results in spontaneous lymphatic reconnection and restoration of lymphatic flow.
Volume: 133
Issue: 2
Pages: 301-10
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Publication
8393164 | J:13199
First Author: Finnerty H
Year: 1993
Journal: Oncogene
Title: Molecular cloning of murine FLT and FLT4.
Volume: 8
Issue: 8
Pages: 2293-8
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Publication
1319394 | J:919
First Author: Galland F
Year: 1992
Journal: Genomics
Title: Chromosomal localization of FLT4, a novel receptor-type tyrosine kinase gene.
Volume: 13
Issue: 2
Pages: 475-8
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Publication
27699240 | J:259746
First Author: Gardenier JC
Year: 2016
Journal: JCI Insight
Title: Diphtheria toxin-mediated ablation of lymphatic endothelial cells results in progressive lymphedema.
Volume: 1
Issue: 15
Pages: e84095
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Publication
32941994 | J:329593
 
First Author: Rehal S
Year: 2020
Journal: Mol Metab
Title: Regulation of lymphatic function and injury by nitrosative stress in obese mice.
Volume: 42
Pages: 101081
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Publication
11250889 | J:68138
First Author: Veikkola T
Year: 2001
Journal: EMBO J
Title: Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice.
Volume: 20
Issue: 6
Pages: 1223-31
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Publication
37454290 | J:339293
First Author: Jannaway M
Year: 2023
Journal: Cell Rep
Title: VEGFR3 is required for button junction formation in lymphatic vessels.
Volume: 42
Issue: 7
Pages: 112777
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Publication
36362253 | J:331094
 
First Author: Li CY
Year: 2022
Journal: Int J Mol Sci
Title: Tumor-Associated Lymphatics Upregulate MHC-II to Suppress Tumor-Infiltrating Lymphocytes.
Volume: 23
Issue: 21
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Publication
25643397 | J:269461
   
First Author: Baeyens N
Year: 2015
Journal: Elife
Title: Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point.
Volume: 4
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Publication
28356442 | J:265373
First Author: Hwangbo C
Year: 2017
Journal: Circulation
Title: Modulation of Endothelial Bone Morphogenetic Protein Receptor Type 2 Activity by Vascular Endothelial Growth Factor Receptor 3 in Pulmonary Arterial Hypertension.
Volume: 135
Issue: 23
Pages: 2288-2298
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Publication
26993803 | J:257380
First Author: Martinez-Corral I
Year: 2016
Journal: Angiogenesis
Title: Vegfr3-CreER (T2) mouse, a new genetic tool for targeting the lymphatic system.
Volume: 19
Issue: 3
Pages: 433-45
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Publication
7724599 | J:24352
First Author: Kaipainen A
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.
Volume: 92
Issue: 8
Pages: 3566-70
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Publication
31932457 | J:285839
First Author: Gloger M
Year: 2020
Journal: Cancer Res
Title: Lymphoma Angiogenesis Is Orchestrated by Noncanonical Signaling Pathways.
Volume: 80
Issue: 6
Pages: 1316-1329
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Publication
21498572 | J:171610
First Author: Calvo CF
Year: 2011
Journal: Genes Dev
Title: Vascular endothelial growth factor receptor 3 directly regulates murine neurogenesis.
Volume: 25
Issue: 8
Pages: 831-44
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Publication
25704818 | J:224173
First Author: Han J
Year: 2015
Journal: Cell Rep
Title: Vascular endothelial growth factor receptor 3 controls neural stem cell activation in mice and humans.
Volume: 10
Issue: 7
Pages: 1158-72
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Publication
36688917 | J:341130
 
First Author: Petkova M
Year: 2023
Journal: J Exp Med
Title: Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation.
Volume: 220
Issue: 4
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Publication
34613809 | J:332934
First Author: Delestre F
Year: 2021
Journal: Sci Transl Med
Title: Alpelisib administration reduced lymphatic malformations in a mouse model and in patients.
Volume: 13
Issue: 614
Pages: eabg0809
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Publication
26389677 | J:226391
First Author: Sabine A
Year: 2015
Journal: J Clin Invest
Title: FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature.
Volume: 125
Issue: 10
Pages: 3861-77
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Publication
28526302 | J:244040
First Author: Gousopoulos E
Year: 2017
Journal: J Invest Dermatol
Title: An Important Role of VEGF-C in Promoting Lymphedema Development.
Volume: 137
Issue: 9
Pages: 1995-2004
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Publication
28024299 | J:244845
First Author: Wong BW
Year: 2017
Journal: Nature
Title: The role of fatty acid β-oxidation in lymphangiogenesis.
Volume: 542
Issue: 7639
Pages: 49-54
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Publication
30582443 | J:292085
First Author: Trincot CE
Year: 2019
Journal: Circ Res
Title: Adrenomedullin Induces Cardiac Lymphangiogenesis After Myocardial Infarction and Regulates Cardiac Edema Via Connexin 43.
Volume: 124
Issue: 1
Pages: 101-113
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Publication
29361560 | J:257930
 
First Author: Zhang Y
Year: 2018
Journal: Development
Title: Transient loss of venous integrity during developmental vascular remodeling leads to red blood cell extravasation and clearance by lymphatic vessels.
Volume: 145
Issue: 3
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Publication
32513927 | J:292002
First Author: Martinez-Corral I
Year: 2020
Journal: Nat Commun
Title: Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation.
Volume: 11
Issue: 1
Pages: 2869
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Publication
37154714 | J:337938
First Author: Tan C
Year: 2023
Journal: EMBO Rep
Title: Endothelial FOXC1 and FOXC2 promote intestinal regeneration after ischemia-reperfusion injury.
Volume: 24
Issue: 7
Pages: e56030
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Publication
29141865 | J:256206
First Author: Antila S
Year: 2017
Journal: J Exp Med
Title: Development and plasticity of meningeal lymphatic vessels.
Volume: 214
Issue: 12
Pages: 3645-3667
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Publication
35728595 | J:326790
First Author: Niec RE
Year: 2022
Journal: Cell Stem Cell
Title: Lymphatics act as a signaling hub to regulate intestinal stem cell activity.
Volume: 29
Issue: 7
Pages: 1067-1082.e18
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Publication
30102256 | J:266192
First Author: Wu H
Year: 2018
Journal: J Clin Invest
Title: Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes.
Volume: 128
Issue: 9
Pages: 4025-4043
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Publication
25314967 | J:244674
First Author: Liu X
Year: 2014
Journal: Sci Signal
Title: Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.
Volume: 7
Issue: 347
Pages: ra97
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Publication
33060128 | J:301556
 
First Author: Cha B
Year: 2020
Journal: Development
Title: YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling.
Volume: 147
Issue: 23
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Publication
20179099 | J:159024
First Author: Ichise T
Year: 2010
Journal: Development
Title: H-, N- and Kras cooperatively regulate lymphatic vessel growth by modulating VEGFR3 expression in lymphatic endothelial cells in mice.
Volume: 137
Issue: 6
Pages: 1003-13
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Protein Coding Gene
MGP_CAROLIEiJ_G0016275 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018234 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018202 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017985 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_95561 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018623 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017547 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017960 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018067 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018061 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018142 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018086 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018667 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017325 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017600 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017411 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017120 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
15536152 | J:98130
First Author: Sugaya M
Year: 2005
Journal: Blood
Title: Lymphatic dysfunction in transgenic mice expressing KSHV k-cyclin under the control of the VEGFR-3 promoter.
Volume: 105
Issue: 6
Pages: 2356-63
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Publication
22101523 | J:181796
First Author: Karlsen TV
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Minimally invasive quantification of lymph flow in mice and rats by imaging depot clearance of near-infrared albumin.
Volume: 302
Issue: 2
Pages: H391-401
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Publication
- | J:13981
 
First Author: Lyon MF
Year: 1984
Journal: Mouse News Lett
Title: Chylous ascites (Chy)
Volume: 71
Pages: 26
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Publication
20823159 | J:164204
First Author: Proulx ST
Year: 2010
Journal: Cancer Res
Title: Quantitative imaging of lymphatic function with liposomal indocyanine green.
Volume: 70
Issue: 18
Pages: 7053-62
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Publication
30621519 | J:339485
First Author: Yanev P
Year: 2020
Journal: J Cereb Blood Flow Metab
Title: Impaired meningeal lymphatic vessel development worsens stroke outcome.
Volume: 40
Issue: 2
Pages: 263-275
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Publication
27329584 | J:346515
First Author: Steinskog ES
Year: 2016
Journal: Oncotarget
Title: Impaired lymphatic function accelerates cancer growth.
Volume: 7
Issue: 29
Pages: 45789-45802
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Publication
31369756 | J:282116
First Author: Wagner M
Year: 2019
Journal: Am J Pathol
Title: Blockade of Lymphangiogenesis Shapes Tumor-Promoting Adipose Tissue Inflammation.
Volume: 189
Issue: 10
Pages: 2102-2114
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Publication
28935759 | J:269170
First Author: Karlsen TV
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Lymphangiogenesis Facilitates Initial Lymph Formation and Enhances the Dendritic Cell Mobilizing Chemokine CCL21 Without Affecting Migration.
Volume: 37
Issue: 11
Pages: 2128-2135
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Publication
27525437 | J:237244
First Author: Lund AW
Year: 2016
Journal: J Clin Invest
Title: Lymphatic vessels regulate immune microenvironments in human and murine melanoma.
Volume: 126
Issue: 9
Pages: 3389-402
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Publication
16675495 | J:134296
First Author: Karlsen TV
Year: 2006
Journal: J Physiol
Title: Transcapillary fluid balance consequences of missing initial lymphatics studied in a mouse model of primary lymphoedema.
Volume: 574
Issue: Pt 2
Pages: 583-96
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Publication
24656836 | J:209991
First Author: Zhang Y
Year: 2014
Journal: Immunity
Title: Activation of vascular endothelial growth factor receptor-3 in macrophages restrains TLR4-NF-κB signaling and protects against endotoxin shock.
Volume: 40
Issue: 4
Pages: 501-14
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Publication
34551997 | J:339431
First Author: Liu H
Year: 2021
Journal: J Am Soc Nephrol
Title: Heterozygous Mutation of Vegfr3 Reduces Renal Lymphatics without Renal Dysfunction.
Volume: 32
Issue: 12
Pages: 3099-3113
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Publication
20110415 | J:158516
First Author: Rutkowski JM
Year: 2010
Journal: Am J Pathol
Title: Dermal collagen and lipid deposition correlate with tissue swelling and hydraulic conductivity in murine primary lymphedema.
Volume: 176
Issue: 3
Pages: 1122-9
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Publication
30618798 | J:290407
 
First Author: Shew T
Year: 2018
Journal: Front Physiol
Title: VEGFR-3 Signaling Regulates Triglyceride Retention and Absorption in the Intestine.
Volume: 9
Pages: 1783
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Publication
26077718 | J:226354
First Author: Aspelund A
Year: 2015
Journal: J Exp Med
Title: A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules.
Volume: 212
Issue: 7
Pages: 991-9
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Publication
16877368 | J:111981
First Author: Karpanen T
Year: 2006
Journal: Am J Pathol
Title: Lymphangiogenic growth factor responsiveness is modulated by postnatal lymphatic vessel maturation.
Volume: 169
Issue: 2
Pages: 708-18
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Publication
25800053 | J:240164
First Author: Coon BG
Year: 2015
Journal: J Cell Biol
Title: Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex.
Volume: 208
Issue: 7
Pages: 975-86
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Publication
20837699 | J:269083
First Author: Huggenberger R
Year: 2010
Journal: J Exp Med
Title: Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation.
Volume: 207
Issue: 10
Pages: 2255-69
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Publication
12070340 | J:77349
First Author: Kubo H
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Blockade of vascular endothelial growth factor receptor-3 signaling inhibits fibroblast growth factor-2-induced lymphangiogenesis in mouse cornea.
Volume: 99
Issue: 13
Pages: 8868-73
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Publication
15632376 | J:95237
First Author: Pytowski B
Year: 2005
Journal: J Natl Cancer Inst
Title: Complete and specific inhibition of adult lymphatic regeneration by a novel VEGFR-3 neutralizing antibody.
Volume: 97
Issue: 1
Pages: 14-21
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Publication
16470183 | J:106840
First Author: Kajiya K
Year: 2006
Journal: J Invest Dermatol
Title: An important role of lymphatic vessels in the control of UVB-induced edema formation and inflammation.
Volume: 126
Issue: 4
Pages: 919-21
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Publication
19808642 | J:154707
First Author: Chung ES
Year: 2009
Journal: Am J Pathol
Title: Contribution of macrophages to angiogenesis induced by vascular endothelial growth factor receptor-3-specific ligands.
Volume: 175
Issue: 5
Pages: 1984-92
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Publication
24036251 | J:202474
First Author: Rutkowski JM
Year: 2013
Journal: Am J Pathol
Title: VEGFR-3 neutralization inhibits ovarian lymphangiogenesis, follicle maturation, and murine pregnancy.
Volume: 183
Issue: 5
Pages: 1596-607
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Publication
25597700 | J:219575
First Author: Harding J
Year: 2015
Journal: Am J Pathol
Title: Lymphangiogenesis is induced by mycobacterial granulomas via vascular endothelial growth factor receptor-3 and supports systemic T-cell responses against mycobacterial antigen.
Volume: 185
Issue: 2
Pages: 432-45
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GXD Expression
GXD Expression
   
Probe: MGI:1303391
Assay Type: RT-PCR
Annotation Date: 1998-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1314617
Age: embryonic day 9.5
Image: 6
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1303391
Assay Type: RT-PCR
Annotation Date: 1998-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1314617
Age: embryonic day 9.5
Image: 6
Specimen Label: -/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:1329000
Assay Type: RT-PCR
Annotation Date: 1999-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:1329056
Age: embryonic day 8.5
Image: 1
Specimen Label: -/-
Detected: true
Specimen Num: 2
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