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Search results 1 to 100 out of 384 for Folr1

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0.044s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Domain
Type: Family
Description: The folate receptors are involved in the transport and maintenance of intracellular levels of folate. Folate receptor alpha (FR-alpha, FOLR1) and beta (FR-beta, FOLR2) are glycosyl phosphatidylinositol (GPI)-anchored proteins that facilitate unidirectional transport of folates into cells via receptor-mediated endocytosis [, ].This entry represents the folate receptor alpha. Its structure has been revealed [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein
Organism: Mus musculus
Length: 206  
Fragment?: true
Protein
Organism: Mus musculus
Length: 203  
Fragment?: true
Publication
First Author: Zhu H
Year: 2007
Journal: Birth Defects Res A Clin Mol Teratol
Title: Cardiovascular abnormalities in Folr1 knockout mice and folate rescue.
Volume: 79
Issue: 4
Pages: 257-68
Publication  
First Author: Zhu H
Year: 2007
Journal: BMC Dev Biol
Title: Differentially expressed genes in embryonic cardiac tissues of mice lacking Folr1 gene activity.
Volume: 7
Pages: 128
Protein
Organism: Mus musculus
Length: 255  
Fragment?: false
Protein
Organism: Mus musculus
Length: 54  
Fragment?: true
Protein
Organism: Mus musculus
Length: 42  
Fragment?: true
Protein
Organism: Mus musculus
Length: 160  
Fragment?: true
Protein
Organism: Mus musculus
Length: 137  
Fragment?: true
Protein
Organism: Mus musculus
Length: 156  
Fragment?: true
Protein
Organism: Mus musculus
Length: 103  
Fragment?: true
Protein
Organism: Mus musculus
Length: 53  
Fragment?: true
Publication
First Author: Verma RS
Year: 1992
Journal: J Biol Chem
Title: Evidence that the hydrophobicity of isolated, in situ, and de novo-synthesized native human placental folate receptors is a function of glycosyl-phosphatidylinositol anchoring to membranes.
Volume: 267
Issue: 6
Pages: 4119-27
Publication
First Author: Henderson GI
Year: 1995
Journal: J Lab Clin Med
Title: Maternal-to-fetal transfer of 5-methyltetrahydrofolate by the perfused human placental cotyledon: evidence for a concentrative role by placental folate receptors in fetal folate delivery.
Volume: 126
Issue: 2
Pages: 184-203
Publication
First Author: Chen C
Year: 2013
Journal: Nature
Title: Structural basis for molecular recognition of folic acid by folate receptors.
Volume: 500
Issue: 7463
Pages: 486-9
Publication  
First Author: Della-Longa S
Year: 2013
Journal: J Mol Graph Model
Title: Structural and functional insights on folate receptor α (FRα) by homology modeling, ligand docking and molecular dynamics.
Volume: 44
Pages: 197-207
Publication
First Author: Alam C
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Upregulation of reduced folate carrier by vitamin D enhances brain folate uptake in mice lacking folate receptor alpha.
Volume: 116
Issue: 35
Pages: 17531-17540
Publication
First Author: Warner DR
Year: 2011
Journal: Cell Biol Int
Title: Altered signal transduction in Folr1-/- mouse embryo fibroblasts.
Volume: 35
Issue: 12
Pages: 1253-9
Publication
First Author: Iskandar BJ
Year: 2010
Journal: J Clin Invest
Title: Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation.
Volume: 120
Issue: 5
Pages: 1603-16
Publication
First Author: Kooistra M
Year: 2013
Journal: Biol Reprod
Title: Folate transport in mouse cumulus-oocyte complexes and preimplantation embryos.
Volume: 89
Issue: 3
Pages: 63
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Bolton JA
Year: 1999
Journal: Gene
Title: Retinoic acid-dependent upregulation of mouse folate receptor-alpha expression in embryonic stem cells, and conservation of alternative splicing patterns.
Volume: 230
Issue: 2
Pages: 215-24
Publication
First Author: Brigle KE
Year: 1992
Journal: J Biol Chem
Title: Insertion of an intracisternal A particle within the 5'-regulatory region of a gene encoding folate-binding protein in L1210 leukemia cells in response to low folate selection. Association with increased protein expression.
Volume: 267
Issue: 31
Pages: 22351-5
Publication
First Author: Tang LS
Year: 2003
Journal: Birth Defects Res A Clin Mol Teratol
Title: Neural and orofacial defects in Folp1 knockout mice [corrected].
Volume: 67
Issue: 4
Pages: 209-18
Publication
First Author: Finnell RH
Year: 2002
Journal: J Nutr
Title: DNA methylation in Folbp1 knockout mice supplemented with folic acid during gestation.
Volume: 132
Issue: 8 Suppl
Pages: 2457S-2461S
Publication
First Author: Spiegelstein O
Year: 2004
Journal: Dev Dyn
Title: Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation.
Volume: 231
Issue: 1
Pages: 221-31
Publication
First Author: Spiegelstein O
Year: 2004
Journal: Neurochem Res
Title: Folate-regulated changes in gene expression in the anterior neural tube of folate binding protein-1 (Folbp1)-deficient murine embryos.
Volume: 29
Issue: 6
Pages: 1105-12
Publication
First Author: Smith SB
Year: 1999
Journal: Invest Ophthalmol Vis Sci
Title: Expression of folate receptor alpha in the mammalian retinol pigmented epithelium and retina.
Volume: 40
Issue: 5
Pages: 840-8
Publication
First Author: Saitsu H
Year: 2003
Journal: Dev Dyn
Title: Spatial and temporal expression of folate-binding protein 1 (Fbp1) is closely associated with anterior neural tube closure in mice.
Volume: 226
Issue: 1
Pages: 112-7
Publication
First Author: Xia W
Year: 2009
Journal: Blood
Title: A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages.
Volume: 113
Issue: 2
Pages: 438-46
Publication  
First Author: Boshnjaku V
Year: 2012
Journal: Sci Rep
Title: Nuclear localization of folate receptor alpha: a new role as a transcription factor.
Volume: 2
Pages: 980
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:5556234
Age: postnatal
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:5556242
Age: postnatal
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5556234
Age: postnatal
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:2652687
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2652701
Age: embryonic day 18.0
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2652687
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2652712
Age: postnatal adult
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2652687
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2652712
Age: postnatal adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6444299
Assay Type: RT-PCR
Annotation Date: 2020-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6445578
Age: postnatal week 5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6444299
Assay Type: RT-PCR
Annotation Date: 2020-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6445578
Age: postnatal week 5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:5556234
Age: embryonic day 1.0
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:5556242
Age: embryonic day 1.0
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:5556234
Age: embryonic day 2.0
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:5556242
Age: embryonic day 2.0
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:5556234
Age: embryonic day 2.5
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:5556242
Age: embryonic day 2.5
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:5556234
Age: embryonic day 3.0
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:5556242
Age: embryonic day 3.0
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:2652687
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604226
Stage: TS26
Assay Id: MGI:2652712
Age: embryonic day 18.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2652687
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604226
Stage: TS26
Assay Id: MGI:2652712
Age: embryonic day 18.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2652687
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185812
Stage: TS12
Assay Id: MGI:2652701
Age: embryonic day 8.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2652687
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185814
Stage: TS14
Assay Id: MGI:2652701
Age: embryonic day 9.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2652687
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185816
Stage: TS16
Assay Id: MGI:2652701
Age: embryonic day 10.0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2652687
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185820
Stage: TS20
Assay Id: MGI:2652701
Age: embryonic day 12.0
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:5556234
Age: embryonic day 0.5
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:5556242
Age: embryonic day 0.5
Detected: false
Specimen Num: 4
GXD Expression        
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Not Specified
Sex: Female
Emaps: EMAPS:3526728
Stage: TS28
Assay Id: MGI:5556234
Age: postnatal
Specimen Num: 2
GXD Expression        
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Not Specified
Sex: Female
Emaps: EMAPS:3526728
Stage: TS28
Assay Id: MGI:5556242
Age: postnatal
Specimen Num: 1
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5556234
Age: embryonic day 3.5
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5556242
Age: embryonic day 3.5
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:5556234
Age: postnatal
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:5556242
Age: postnatal
Detected: false
Specimen Num: 3
GXD Expression        
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Not Specified
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:5556234
Age: postnatal
Specimen Num: 2
GXD Expression        
Probe: MGI:5556068
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Not Specified
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:5556242
Age: postnatal
Specimen Num: 1
GXD Expression      
Probe: MGI:2652687
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:2652701
Age: embryonic day 16.0
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2652687
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:2652701
Age: embryonic day 18.0
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5310483
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5423806
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:988642
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2966328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5538796
Age: postnatal day 84
Image: GUDMAP:14886
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5310483
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716122
Stage: TS22
Assay Id: MGI:5423806
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310483
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691622
Stage: TS22
Assay Id: MGI:5423806
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:988642
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2835226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5538796
Age: embryonic day 17.5
Image: GUDMAP:14885
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:988642
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2835228
Stage: TS28
Assay Id: MGI:5538796
Age: postnatal day 84
Image: GUDMAP:14886
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:5310483
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1760622
Stage: TS22
Assay Id: MGI:5423806
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:988642
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:2813028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5538796
Age: postnatal day 84
Image: GUDMAP:14886
Specimen Num: 2
GXD Expression  
Probe: MGI:988642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1636323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824894
Age: embryonic day 14.5
Image: euxassay_000743_10
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:988642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1636323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824894
Age: embryonic day 14.5
Image: euxassay_000743_11
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:988642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1636323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824894
Age: embryonic day 14.5
Image: euxassay_000743_12
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:988642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1636323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824894
Age: embryonic day 14.5
Image: euxassay_000743_13
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:988642
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1636323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824894
Age: embryonic day 14.5
Image: euxassay_000743_14
Detected: true
Specimen Num: 12