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Search results 1 to 98 out of 98 for Folr2

0.046s

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
2350 | FOLR2
Type: gene
Organism: human
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Gene
507672 | FOLR2
Type: gene
Organism: cattle
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Gene
100614013 | FOLR2
Type: gene
Organism: chimpanzee
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Gene
718405 | FOLR2
Type: gene
Organism: macaque, rhesus
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Gene
293154 | Folr2
Type: gene
Organism: rat
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Protein Domain
IPR032937 | FOLR2
Type: Family
Description: The folate receptors are involved in the transport and maintenance of intracellular levels of folate. Folate receptor alpha (FR-alpha, FOLR1) and beta (FR-beta, FOLR2) are glycosyl phosphatidylinositol (GPI)-anchored proteins that facilitate unidirectional transport of folates into cells via receptor-mediated endocytosis [, ].This entry represents folate receptor beta. FOLR2 is expressed on the proinflammatory subset of monocytes and can be targeted selectively with folate-linked drugs [].
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Protein Coding Gene
MGI:95569 | Folr2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25015955 | -
First Author: Shen J
Year: 2014
Journal: J Leukoc Biol
Title: Folate receptor-β constitutes a marker for human proinflammatory monocytes.
Volume: 96
Issue: 4
Pages: 563-70
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Publication
1310989 | -
First Author: Verma RS
Year: 1992
Journal: J Biol Chem
Title: Evidence that the hydrophobicity of isolated, in situ, and de novo-synthesized native human placental folate receptors is a function of glycosyl-phosphatidylinositol anchoring to membranes.
Volume: 267
Issue: 6
Pages: 4119-27
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Publication
7636392 | -
First Author: Henderson GI
Year: 1995
Journal: J Lab Clin Med
Title: Maternal-to-fetal transfer of 5-methyltetrahydrofolate by the perfused human placental cotyledon: evidence for a concentrative role by placental folate receptors in fetal folate delivery.
Volume: 126
Issue: 2
Pages: 184-203
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Protein
Q05685
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: false
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Protein
A0A1B0GQW7
Organism: Mus musculus/domesticus
Length: 87  
Fragment?: true
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Protein
A0A1B0GSV4
Organism: Mus musculus/domesticus
Length: 177  
Fragment?: true
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Publication
27122634 | J:319636
First Author: Meredith M
Year: 2016
Journal: Biol Reprod
Title: Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size.
Volume: 94
Issue: 6
Pages: 125
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Publication
23904512 | J:203885
First Author: Kooistra M
Year: 2013
Journal: Biol Reprod
Title: Folate transport in mouse cumulus-oocyte complexes and preimplantation embryos.
Volume: 89
Issue: 3
Pages: 63
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Protein Coding Gene
MGP_CAROLIEiJ_G0030067 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032589 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032565 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032501 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032576 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032290 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_95569 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033073 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031616 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032256 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032408 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032364 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032497 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032398 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033095 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031334 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031733 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013288 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031178 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
8307991 | J:16810
First Author: Brigle KE
Year: 1994
Journal: J Biol Chem
Title: Increased expression and genomic organization of a folate-binding protein homologous to the human placental isoform in L1210 murine leukemia cell lines with a defective reduced folate carrier.
Volume: 269
Issue: 6
Pages: 4267-72
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Publication
14745917 | J:87144
First Author: Spiegelstein O
Year: 2003
Journal: Birth Defects Res A Clin Mol Teratol
Title: Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice.
Volume: 67
Issue: 12
Pages: 974-8
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Publication
15282741 | J:91659
First Author: Kappen C
Year: 2004
Journal: Genesis
Title: Folate modulates Hox gene-controlled skeletal phenotypes.
Volume: 39
Issue: 3
Pages: 155-66
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Publication
31824505 | J:297955
 
First Author: Schniering J
Year: 2019
Journal: Front Immunol
Title: 18F-AzaFol for Detection of Folate Receptor-β Positive Macrophages in Experimental Interstitial Lung Disease-A Proof-of-Concept Study.
Volume: 10
Pages: 2724
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Publication
25375039 | J:318249
First Author: Han W
Year: 2015
Journal: Am J Respir Cell Mol Biol
Title: Molecular imaging of folate receptor β-positive macrophages during acute lung inflammation.
Volume: 53
Issue: 1
Pages: 50-9
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GXD Expression
GXD Expression
     
Probe: MGI:2652688
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:2652708
Age: embryonic day 16.0
Specimen Label: GD 16
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:2652688
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:2652708
Age: embryonic day 18.0
Specimen Label: GD 18
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:2652688
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2652708
Age: embryonic day 18.0
Specimen Label: Placenta
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:5556069
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Female
Emaps: EMAPS:3526728
Stage: TS28
Assay Id: MGI:5556231
Age: postnatal
Specimen Label: C
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5556069
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:5556231
Age: postnatal
Specimen Label: C
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5556069
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:5556231
Age: postnatal
Specimen Label: G
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5556069
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:5556231
Age: embryonic day 0.5
Specimen Label: 1
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5556069
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:5556231
Age: embryonic day 1.0
Specimen Label: 2
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:5556069
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:5556231
Age: embryonic day 2.0
Specimen Label: 4
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:5556069
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:5556231
Age: embryonic day 2.5
Specimen Label: 8
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:5556069
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:5556231
Age: embryonic day 3.0
Specimen Label: M
Detected: false
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:5556069
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5556231
Age: embryonic day 3.5
Specimen Label: B
Detected: false
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:5556069
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5556231
Age: postnatal
Specimen Label: +
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:5556069
Assay Type: RT-PCR
Annotation Date: 2014-04-09
Strength: Absent
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:5556231
Age: postnatal
Specimen Label: E
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2652688
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185812
Stage: TS12
Assay Id: MGI:2652708
Age: embryonic day 8.0
Specimen Label: GD 8
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2652688
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185814
Stage: TS14
Assay Id: MGI:2652708
Age: embryonic day 9.0
Specimen Label: GD 9
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2652688
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185816
Stage: TS16
Assay Id: MGI:2652708
Age: embryonic day 10.0
Specimen Label: GD 10
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2652688
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185820
Stage: TS20
Assay Id: MGI:2652708
Age: embryonic day 12.0
Specimen Label: GD 12
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2652688
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604226
Stage: TS26
Assay Id: MGI:2652713
Age: embryonic day 18.0
Specimen Label: Embryonic tissue 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2652688
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604226
Stage: TS26
Assay Id: MGI:2652713
Age: embryonic day 18.0
Specimen Label: Embryonic tissue 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2652688
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2652713
Age: postnatal adult
Specimen Label: Maternal tissue 1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2652688
Assay Type: RNase protection
Annotation Date: 2003-03-28
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2652713
Age: postnatal adult
Specimen Label: Maternal tissue 2
Detected: true
Specimen Num: 4
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Publication
33563975 | J:304543
First Author: Rodriguez-Garcia A
Year: 2021
Journal: Nat Commun
Title: CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy.
Volume: 12
Issue: 1
Pages: 877
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Publication
1894617 | J:11440
First Author: Brigle KE
Year: 1991
Journal: J Biol Chem
Title: Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement.
Volume: 266
Issue: 26
Pages: 17243-9
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Publication
10508523 | J:57765
First Author: Piedrahita JA
Year: 1999
Journal: Nat Genet
Title: Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development.
Volume: 23
Issue: 2
Pages: 228-32
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Publication
15703271 | J:110064
First Author: Birn H
Year: 2005
Journal: J Am Soc Nephrol
Title: Renal tubular reabsorption of folate mediated by folate binding protein 1.
Volume: 16
Issue: 3
Pages: 608-15
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Publication
15694460 | J:95928
First Author: Spiegelstein O
Year: 2005
Journal: Toxicol Appl Pharmacol
Title: Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies.
Volume: 203
Issue: 1
Pages: 18-26
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Publication
8304978 | J:16724
First Author: Brigle KE
Year: 1994
Journal: Biochem Pharmacol
Title: Increased expression and characterization of two distinct folate binding proteins in murine erythroleukemia cells.
Volume: 47
Issue: 2
Pages: 337-45
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Publication
9166787 | J:40506
First Author: Shen F
Year: 1997
Journal: Biochemistry
Title: Identification of amino acid residues that determine the differential ligand specificities of folate receptors alpha and beta.
Volume: 36
Issue: 20
Pages: 6157-63
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Publication
9973545 | J:53758
First Author: Barber RC
Year: 1999
Journal: Mol Genet Metab
Title: Expression patterns of folate binding proteins one and two in the developing mouse embryo.
Volume: 66
Issue: 1
Pages: 31-9
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Publication
11111049 | J:66219
First Author: Spiegelstein O
Year: 2000
Journal: Gene
Title: Identification of two putative novel folate receptor genes in humans and mouse.
Volume: 258
Issue: 1-2
Pages: 117-25
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Publication
34995099 | J:335290
First Author: Dick SA
Year: 2022
Journal: Sci Immunol
Title: Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles.
Volume: 7
Issue: 67
Pages: eabf7777
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Publication
22365888 | J:184371
First Author: Cherukad J
Year: 2012
Journal: Placenta
Title: Spatial and temporal expression of folate-related transporters and metabolic enzymes during mouse placental development.
Volume: 33
Issue: 5
Pages: 440-8
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Publication
17062627 | J:137511
First Author: Lin Q
Year: 2006
Journal: Nucleic Acids Res
Title: Mutagenesis of diploid mammalian genes by gene entrapment.
Volume: 34
Issue: 20
Pages: e139
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Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:346132
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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