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Search results 1 to 100 out of 455 for Fosb

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
2354 | FOSB
Type: gene
Organism: human
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Gene
107969757 | FOSB
Type: gene
Organism: chimpanzee
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Gene
484445 | FOSB
Type: gene
Organism: dog, domestic
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Gene
540819 | FOSB
Type: gene
Organism: cattle
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Gene
100360880 | Fosb
Type: gene
Organism: rat
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Gene
715896 | FOSB
Type: gene
Organism: macaque, rhesus
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Gene
100490871 | fosb
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR029813 | FosB
Type: Family
Description: Transcription factor activator protein (AP)-1, comprising Jun (c-Jun, JunB, and JunD) and Fos (c-Fos, FosB, Fra1, and Fra2) family members, plays a central role in regulating gene transcription in various biological processes []. Fos protein family members form stable heterodimerswith Jun proteins and thereby enhance their DNA-bindingactivity []. This entry reprsents FosB []. FosB-null mice display impaired adult hippocampal neurogenesis and spontaneous epilepsy with depressive behavior [].
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Gene
492346 | fosb
Type: gene
Organism: zebrafish
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Protein Coding Gene
MGI:95575 | Fosb
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
23303048 | J:264668
First Author: Yutsudo N
Year: 2013
Journal: Neuropsychopharmacology
Title: fosB-null mice display impaired adult hippocampal neurogenesis and spontaneous epilepsy with depressive behavior.
Volume: 38
Issue: 5
Pages: 895-906
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Publication
2498083 | J:15672
First Author: Zerial M
Year: 1989
Journal: EMBO J
Title: The product of a novel growth factor activated gene, fos B, interacts with JUN proteins enhancing their DNA binding activity.
Volume: 8
Issue: 3
Pages: 805-13
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Protein
P13346
Organism: Mus musculus/domesticus
Length: 338  
Fragment?: false
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Protein
I3PGL9
Organism: Mus musculus/domesticus
Length: 125  
Fragment?: true
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Protein
I3PGL7
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: true
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Protein
A0A140LHS3
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: false
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Protein
A0A140LJH0
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: false
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Protein
A0A140LIT4
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: false
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Protein
A0A140LHW0
Organism: Mus musculus/domesticus
Length: 299  
Fragment?: false
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Publication
1741260 | J:2957
First Author: Lazo PS
Year: 1992
Journal: Nucleic Acids Res
Title: Structure and mapping of the fosB gene. FosB downregulates the activity of the fosB promoter.
Volume: 20
Issue: 2
Pages: 343-50
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Publication
30902680 | J:276166
 
First Author: Manning CE
Year: 2019
Journal: Neuroscience
Title: Hippocampal Subgranular Zone FosB Expression Is Critical for Neurogenesis and Learning.
Volume: 406
Pages: 225-233
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Publication
18407360 | J:148647
First Author: Solecki W
Year: 2008
Journal: Behav Brain Res
Title: Role of fosB in behaviours related to morphine reward and spatial memory.
Volume: 190
Issue: 2
Pages: 212-7
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Publication
9294222 | J:42926
First Author: Hiroi N
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects.
Volume: 94
Issue: 19
Pages: 10397-402
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Publication
23904356 | -
First Author: Brenner DA
Year: 2014
Journal: Hepatology
Title: Fra, Fra away: the complex role of activator protein 1 in liver injury.
Volume: 59
Issue: 1
Pages: 19-20
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Publication
23319622 | J:193696
First Author: Grueter BA
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: ∆FosB differentially modulates nucleus accumbens direct and indirect pathway function.
Volume: 110
Issue: 5
Pages: 1923-8
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Protein
A2RSD4
Organism: Mus musculus/domesticus
Length: 338  
Fragment?: false
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Publication
12223567 | J:79140
First Author: Werme M
Year: 2002
Journal: J Neurosci
Title: Delta FosB regulates wheel running.
Volume: 22
Issue: 18
Pages: 8133-8
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Publication
20473292 | J:165057
First Author: Vialou V
Year: 2010
Journal: Nat Neurosci
Title: DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses.
Volume: 13
Issue: 6
Pages: 745-52
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Publication
- | J:276191
     
First Author: Ohnishi YN
Year: 2017
Journal: bioRxiv
Title: Generation and validation of a floxed FosB mouse line.
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Publication
12424143 | -
First Author: Reddy SP
Year: 2002
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Role and regulation of activator protein-1 in toxicant-induced responses of the lung.
Volume: 283
Issue: 6
Pages: L1161-78
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Publication
8668344 | J:33415
First Author: Gruda MC
Year: 1996
Journal: Oncogene
Title: Expression of FosB during mouse development: normal development of FosB knockout mice.
Volume: 12
Issue: 10
Pages: 2177-85
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Publication
15276803 | J:102266
First Author: Korkosz A
Year: 2004
Journal: Physiol Behav
Title: Dissociation of ethanol and saccharin preference in fosB knockout mice.
Volume: 82
Issue: 2-3
Pages: 391-5
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Publication
8706134 | J:34461
First Author: Brown JR
Year: 1996
Journal: Cell
Title: A defect in nurturing in mice lacking the immediate early gene fosB.
Volume: 86
Issue: 2
Pages: 297-309
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Publication
18753407 | J:220449
First Author: Ohnishi YN
Year: 2008
Journal: Mol Biol Cell
Title: Antagonistic regulation of cell-matrix adhesion by FosB and DeltaFosB/Delta2DeltaFosB encoded by alternatively spliced forms of fosB transcripts.
Volume: 19
Issue: 11
Pages: 4717-29
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Publication
21996678 | J:180070
First Author: Ramachandran A
Year: 2011
Journal: Am J Pathol
Title: FosB regulates stretch-induced expression of extracellular matrix proteins in smooth muscle.
Volume: 179
Issue: 6
Pages: 2977-89
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Publication
9712664 | J:110995
First Author: Hiroi N
Year: 1998
Journal: J Neurosci
Title: Essential role of the fosB gene in molecular, cellular, and behavioral actions of chronic electroconvulsive seizures.
Volume: 18
Issue: 17
Pages: 6952-62
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Publication
21679928 | J:220448
First Author: Ohnishi YN
Year: 2011
Journal: Biol Psychiatry
Title: FosB is essential for the enhancement of stress tolerance and antagonizes locomotor sensitization by ΔFosB.
Volume: 70
Issue: 5
Pages: 487-95
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Publication
17468183 | J:121766
First Author: Zhu H
Year: 2007
Journal: Hum Mol Genet
Title: Pleiotropic impact of constitutive fosB inactivation on nicotine-induced behavioral alterations and stress-related traits in mice.
Volume: 16
Issue: 7
Pages: 820-36
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Publication
16699069 | J:116440
First Author: Alfonso-Jaume MA
Year: 2006
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac ischemia-reperfusion injury induces matrix metalloproteinase-2 expression through the AP-1 components FosB and JunB.
Volume: 291
Issue: 4
Pages: H1838-46
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Publication
12376177 | J:79752
First Author: Mathieson WB
Year: 2002
Journal: Brain Res
Title: FOS and FOSB expression in the medial preoptic nucleus pars compacta of maternally active C57BL/6J and DBA/2J mice.
Volume: 952
Issue: 2
Pages: 170-5
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Publication
24771617 | J:211298
First Author: Nomaru H
Year: 2014
Journal: Glia
Title: Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia.
Volume: 62
Issue: 8
Pages: 1284-98
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Publication
28724635 | J:245973
First Author: Kotla S
Year: 2017
Journal: J Biol Chem
Title: Heterodimers of the transcriptional factors NFATc3 and FosB mediate tissue factor expression for 15(S)-hydroxyeicosatetraenoic acid-induced monocyte trafficking.
Volume: 292
Issue: 36
Pages: 14885-14901
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Publication
16380431 | J:104693
First Author: Levine AA
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum.
Volume: 102
Issue: 52
Pages: 19186-91
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Publication
9204924 | J:41381
First Author: Mandelzys A
Year: 1997
Journal: J Neurosci
Title: Absence of a persistently elevated 37 kDa fos-related antigen and AP-1-like DNA-binding activity in the brains of kainic acid-treated fosB null mice.
Volume: 17
Issue: 14
Pages: 5407-15
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Publication
27282087 | J:236496
 
First Author: Kormos V
Year: 2016
Journal: Neuroscience
Title: Reduced response to chronic mild stress in PACAP mutant mice is associated with blunted FosB expression in limbic forebrain and brainstem centers.
Volume: 330
Pages: 335-58
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Publication
18433296 | J:150160
First Author: Sabatakos G
Year: 2008
Journal: J Bone Miner Res
Title: Doubly truncated FosB isoform (Delta2DeltaFosB) induces osteosclerosis in transgenic mice and modulates expression and phosphorylation of Smads in osteoblasts independent of intrinsic AP-1 activity.
Volume: 23
Issue: 5
Pages: 584-95
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Publication
25193242 | J:248411
First Author: Feyder M
Year: 2016
Journal: Biol Psychiatry
Title: A Role for Mitogen- and Stress-Activated Kinase 1 in L-DOPA-Induced Dyskinesia and ∆FosB Expression.
Volume: 79
Issue: 5
Pages: 362-71
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Publication
10973317 | J:64495
First Author: Sabatakos G
Year: 2000
Journal: Nat Med
Title: Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis.
Volume: 6
Issue: 9
Pages: 985-90
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Publication
25313003 | J:221455
 
First Author: Ohnishi YN
Year: 2015
Journal: Neuroscience
Title: Functional role of the N-terminal domain of ΔFosB in response to stress and drugs of abuse.
Volume: 284
Pages: 165-70
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Publication
22461201 | J:324969
First Author: Rowe GC
Year: 2012
Journal: J Bone Miner Res
Title: Energy expenditure and bone formation share a common sensitivity to AP-1 transcription in the hypothalamus.
Volume: 27
Issue: 8
Pages: 1649-58
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Publication
29408867 | J:259582
First Author: You JC
Year: 2018
Journal: PLoS One
Title: Genome-wide profiling reveals functional diversification of ∆FosB gene targets in the hippocampus of an Alzheimer's disease mouse model.
Volume: 13
Issue: 2
Pages: e0192508
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Protein
P13346-2
Organism: Mus musculus/domesticus
Length:  
Fragment?: false
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Publication
21962331 | J:283294
First Author: Muschamp JW
Year: 2012
Journal: Biol Psychiatry
Title: ΔFosB enhances the rewarding effects of cocaine while reducing the pro-depressive effects of the kappa-opioid receptor agonist U50488.
Volume: 71
Issue: 1
Pages: 44-50
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Publication
11006248 | J:64729
First Author: Kelz MB
Year: 2000
Journal: Invest Ophthalmol Vis Sci
Title: DeltaFosB-induced cataract.
Volume: 41
Issue: 11
Pages: 3523-38
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UniProt Feature
UniProt Feature
Begin: 1
Description: Protein FosB
Type: chain
End: 338
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Publication
29272704 | J:254428
First Author: Vierbuchen T
Year: 2017
Journal: Mol Cell
Title: AP-1 Transcription Factors and the BAF Complex Mediate Signal-Dependent Enhancer Selection.
Volume: 68
Issue: 6
Pages: 1067-1082.e12
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Publication
17707653 | J:126793
First Author: Kuroda KO
Year: 2007
Journal: Mol Cell Neurosci
Title: ERK-FosB signaling in dorsal MPOA neurons plays a major role in the initiation of parental behavior in mice.
Volume: 36
Issue: 2
Pages: 121-31
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Publication
25347353 | J:219418
First Author: Heller EA
Year: 2014
Journal: Nat Neurosci
Title: Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors.
Volume: 17
Issue: 12
Pages: 1720-7
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Publication
18423429 | J:136816
 
First Author: Kuroda KO
Year: 2008
Journal: Brain Res
Title: Neurobehavioral basis of the impaired nurturing in mice lacking the immediate early gene FosB.
Volume: 1211
Pages: 57-71
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Publication
24118411 | J:320509
First Author: Suzuki T
Year: 2013
Journal: Cancer Sci
Title: Genome-wide analysis of DNA methylation changes induced by gestational arsenic exposure in liver tumors.
Volume: 104
Issue: 12
Pages: 1575-85
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Publication
1900040 | -
First Author: Nakabeppu Y
Year: 1991
Journal: Cell
Title: A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity.
Volume: 64
Issue: 4
Pages: 751-9
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Publication
9710644 | J:111015
First Author: Brown JR
Year: 1998
Journal: Mol Cell Biol
Title: Fos family members induce cell cycle entry by activating cyclin D1.
Volume: 18
Issue: 9
Pages: 5609-19
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Publication
36359852 | J:331436
 
First Author: Novo SG
Year: 2022
Journal: Cells
Title: The Immediate Early Response of Lens Epithelial Cells to Lens Injury.
Volume: 11
Issue: 21
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Publication
22950040 | J:275963
First Author: Chiavegatto S
Year: 2012
Journal: Brain Behav
Title: Hypothalamic expression of Peg3 gene is associated with maternal care differences between SM/J and LG/J mouse strains.
Volume: 2
Issue: 4
Pages: 365-76
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Publication
16313514 | J:103670
First Author: Qiang M
Year: 2005
Journal: J Neurochem
Title: Role of AP-1 in ethanol-induced N-methyl-D-aspartate receptor 2B subunit gene up-regulation in mouse cortical neurons.
Volume: 95
Issue: 5
Pages: 1332-41
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Protein Coding Gene
MGP_CAROLIEiJ_G0029283 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031770 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031746 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031672 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031751 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_95575 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032217 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030816 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031435 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031590 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031542 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031673 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031578 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032245 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030540 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030916 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021143 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030367 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
15652785 | J:101879
First Author: Malik MT
Year: 2005
Journal: Respir Physiol Neurobiol
Title: Impaired ventilatory acclimatization to hypoxia in mice lacking the immediate early gene fos B.
Volume: 145
Issue: 1
Pages: 23-31
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Publication
29891732 | J:263266
First Author: Aleyasin H
Year: 2018
Journal: J Neurosci
Title: Cell-Type-Specific Role of ΔFosB in Nucleus Accumbens In Modulating Intermale Aggression.
Volume: 38
Issue: 26
Pages: 5913-5924
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Publication
32901027 | J:296498
First Author: Eagle AL
Year: 2020
Journal: Nat Commun
Title: Circuit-specific hippocampal ΔFosB underlies resilience to stress-induced social avoidance.
Volume: 11
Issue: 1
Pages: 4484
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Publication
15024071 | J:89071
First Author: Kveiborg M
Year: 2004
Journal: Mol Cell Biol
Title: DeltaFosB induces osteosclerosis and decreases adipogenesis by two independent cell-autonomous mechanisms.
Volume: 24
Issue: 7
Pages: 2820-30
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Publication
19041372 | J:146079
First Author: Ulery-Reynolds PG
Year: 2009
Journal: Neuroscience
Title: Phosphorylation of DeltaFosB mediates its stability in vivo.
Volume: 158
Issue: 2
Pages: 369-72
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Publication
24623766 | J:209604
First Author: Vialou V
Year: 2014
Journal: J Neurosci
Title: Prefrontal cortical circuit for depression- and anxiety-related behaviors mediated by cholecystokinin: role of ΔFosB.
Volume: 34
Issue: 11
Pages: 3878-87
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GXD Expression
GXD Expression
     
Probe: MGI:3053794
Assay Type: Western blot
Annotation Date: 2004-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754926
Stage: TS26
Assay Id: MGI:3053803
Age: embryonic day 18.0
Specimen Label: S
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3053794
Assay Type: Western blot
Annotation Date: 2004-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754926
Stage: TS26
Assay Id: MGI:3053803
Age: embryonic day 18.0
Specimen Label: S
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3053794
Assay Type: Western blot
Annotation Date: 2004-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:3053803
Age: postnatal adult
Specimen Label: Ad
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3053794
Assay Type: Western blot
Annotation Date: 2004-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:3053803
Age: postnatal adult
Specimen Label: Ad
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3053794
Assay Type: Western blot
Annotation Date: 2004-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:3053803
Age: postnatal adult
Specimen Label: Ad
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3053794
Assay Type: Western blot
Annotation Date: 2004-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:3053803
Age: postnatal adult
Specimen Label: Ad
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3815741
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816545
Age: postnatal
Specimen Label: Metaphase II
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3815741
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816545
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3815741
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816545
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: false
Specimen Num: 3
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•
•
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GXD Expression
GXD Expression
     
Probe: MGI:3815741
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816545
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: false
Specimen Num: 4
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•
•
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