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Search results 1 to 100 out of 132 for Fpr3

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0.043s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Bufe B
Year: 2019
Journal: Nat Commun
Title: Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour.
Volume: 10
Issue: 1
Pages: 4889
Publication
First Author: Stempel H
Year: 2016
Journal: J Biol Chem
Title: Strain-specific Loss of Formyl Peptide Receptor 3 in the Murine Vomeronasal and Immune Systems.
Volume: 291
Issue: 18
Pages: 9762-75
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Gao JL
Year: 1998
Journal: Genomics
Title: Differential expansion of the N-formylpeptide receptor gene cluster in human and mouse.
Volume: 51
Issue: 2
Pages: 270-6
Publication
First Author: Rivière S
Year: 2009
Journal: Nature
Title: Formyl peptide receptor-like proteins are a novel family of vomeronasal chemosensors.
Volume: 459
Issue: 7246
Pages: 574-7
Publication
First Author: Liberles SD
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Formyl peptide receptors are candidate chemosensory receptors in the vomeronasal organ.
Volume: 106
Issue: 24
Pages: 9842-7
Publication
First Author: Vaughn MW
Year: 2002
Journal: J Immunol
Title: Identification, cloning, and functional characterization of a murine lipoxin A4 receptor homologue gene.
Volume: 169
Issue: 6
Pages: 3363-9
Publication
First Author: Kurosaka K
Year: 2005
Journal: J Immunol
Title: Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant.
Volume: 174
Issue: 10
Pages: 6257-65
Publication
First Author: Takano T
Year: 1997
Journal: J Exp Med
Title: Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors.
Volume: 185
Issue: 9
Pages: 1693-704
Publication
First Author: Wang ZG
Year: 2002
Journal: Gene
Title: Characterization of two new members of the formyl peptide receptor gene family from 129S6 mice.
Volume: 299
Issue: 1-2
Pages: 57-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Perniss A
Year: 2020
Journal: Immunity
Title: Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides.
Volume: 52
Issue: 4
Pages: 683-699.e11
Publication
First Author: Birkl D
Year: 2019
Journal: FASEB J
Title: Formyl peptide receptor 2 regulates monocyte recruitment to promote intestinal mucosal wound repair.
Volume: 33
Issue: 12
Pages: 13632-13643
Publication
First Author: Gobbetti T
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis.
Volume: 111
Issue: 52
Pages: 18685-90
Publication
First Author: Brancaleone V
Year: 2013
Journal: Blood
Title: A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation.
Volume: 122
Issue: 4
Pages: 608-17
Publication
First Author: Gavins FN
Year: 2003
Journal: Blood
Title: Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms.
Volume: 101
Issue: 10
Pages: 4140-7
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Bufe B
Year: 2012
Journal: J Biol Chem
Title: Formyl peptide receptors from immune and vomeronasal system exhibit distinct agonist properties.
Volume: 287
Issue: 40
Pages: 33644-55
Publication
First Author: Lavigne MC
Year: 2002
Journal: Cell Immunol
Title: The N-formylpeptide receptor (FPR) and a second G(i)-coupled receptor mediate fMet-Leu-Phe-stimulated activation of NADPH oxidase in murine neutrophils.
Volume: 218
Issue: 1-2
Pages: 7-12
Publication
First Author: Levy BD
Year: 2002
Journal: Nat Med
Title: Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4).
Volume: 8
Issue: 9
Pages: 1018-23
Publication
First Author: Coffelt SB
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells.
Volume: 106
Issue: 10
Pages: 3806-11
Publication
First Author: Wu J
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Lipoxin A4 inhibits the production of proinflammatory cytokines induced by β-amyloid in vitro and in vivo.
Volume: 408
Issue: 3
Pages: 382-7
Publication
First Author: Elias I
Year: 2016
Journal: Diabetes
Title: ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance.
Volume: 65
Issue: 8
Pages: 2139-50
Publication
First Author: Kang JW
Year: 2016
Journal: Biochim Biophys Acta
Title: Resolvin D1 protects the liver from ischemia/reperfusion injury by enhancing M2 macrophage polarization and efferocytosis.
Volume: 1861
Issue: 9 Pt A
Pages: 1025-1035
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Park SK
Year: 2014
Journal: Mol Genet Genomics
Title: Nuclear FKBPs, Fpr3 and Fpr4 affect genome-wide genes transcription.
Volume: 289
Issue: 2
Pages: 125-36
Publication
First Author: Wilson LK
Year: 1995
Journal: J Biol Chem
Title: The yeast immunophilin Fpr3 is a physiological substrate of the tyrosine-specific phosphoprotein phosphatase Ptp1.
Volume: 270
Issue: 42
Pages: 25185-93
Protein
Organism: Mus musculus/domesticus
Length: 351  
Fragment?: false
Publication
First Author: Yang D
Year: 2002
Journal: J Leukoc Biol
Title: Human dendritic cells express functional formyl peptide receptor-like-2 (FPRL2) throughout maturation.
Volume: 72
Issue: 3
Pages: 598-607
Publication
First Author: Migeotte I
Year: 2005
Journal: J Exp Med
Title: Identification and characterization of an endogenous chemotactic ligand specific for FPRL2.
Volume: 201
Issue: 1
Pages: 83-93
Protein Domain
Type: Family
Description: Formyl peptide receptors (FPR) are members of the rhodopsin-like G-protein coupled receptor family and are involved in chemotaxis [, ]. They were originally identified by their ability to bind N-formyl peptides (typified by fMet-Leu-Phe (fMLP)), produced by the degradation of either bacterial or host cells [, ]but subsequent ligands have been discovered, containing many microbial agonists derived from both bacteria and viruses [, ].FPRs were initially found on leukocytes, but they are expressed in other cells, for example, immature dendritic cells, platelets, microglial cells, astrocytes, fibroblasts and platelets [, ]. FPRs are expressed at high levels on polymorphonuclear and mononuclear phagocytes. Formyl peptide receptors are not only involved in mediating immune cell response to infection, but also act to suppress the immune system under certain conditions []. The main responses elicited upon ligation of formylated peptides, are those of morphological polarization, locomotion, production of reactive-oxygen species and release of proteolytic enzymes []. There are three formyl peptide receptor subtypes, FPR1, FPR2 and FPR3 [, ]. The sequence similarity between FPR1 and FPR2 is high (69%), and although there is a large sequence similarity also between FPR2 and FPR3 (83%), FPR3 can not bind formylated peptides [, ]. Formyl peptide receptor 3 (FPR3) is primarily a receptor of monocytes, macrophages and dendritic cells. It is also expressed on mouse, but not human, neutrophils [, , ]. Although FPR3 is found in human monocytes, studies have shown that approximately one third of individuals lack cell surface expression of this receptor [, ]. The functions of FPR3, other than directing cell migration, remain to be characterised [, ].
Publication
First Author: Gantz I
Year: 1996
Journal: Cytogenet Cell Genet
Title: Molecular cloning of a novel receptor (CMKLR1) with homology to the chemotactic factor receptors.
Volume: 74
Issue: 4
Pages: 286-90
Protein Domain
Type: Family
Description: Formyl peptide receptors (FPR) are members of the rhodopsin-like G-protein coupled receptor family and are involved in chemotaxis [, ]. They were originally identified by their ability to bind N-formyl peptides (typified by fMet-Leu-Phe (fMLP)), produced by the degradation of either bacterial or host cells [, ]but subsequent ligands have been discovered, containing many microbial agonists derived from both bacteria and viruses [, ].FPRs were initially found on leukocytes, but they are expressed in other cells, for example, immature dendritic cells, platelets, microglial cells, astrocytes, fibroblasts and platelets [, ]. FPRs are expressed at high levels on polymorphonuclear and mononuclear phagocytes. Formyl peptide receptors are not only involved in mediating immune cell response to infection, but also act to suppress the immune system under certain conditions []. The main responses elicited upon ligation of formylated peptides, are those of morphological polarization, locomotion, production of reactive-oxygen species and release of proteolytic enzymes []. There are three formyl peptide receptor subtypes, FPR1, FPR2 and FPR3 [, ]. The sequence similarity between FPR1 and FPR2 is high (69%), and although there is a large sequence similarity also between FPR2 and FPR3 (83%), FPR3 can not bind formylated peptides [, ]. This entry includes the formyl peptide receptors and other related receptors such as C3a and C5a anaphylatoxin chemotactic receptors []and G-protein-coupled receptor CMKlR1 [].
Publication
First Author: Stein B
Year: 2016
Journal: PLoS One
Title: Functional Overexpression of Vomeronasal Receptors Using a Herpes Simplex Virus Type 1 (HSV-1)-Derived Amplicon.
Volume: 11
Issue: 5
Pages: e0156092
Publication
First Author: Buss NA
Year: 2015
Journal: FASEB J
Title: Targeting the annexin 1-formyl peptide receptor 2/ALX pathway affords protection against bacterial LPS-induced pathologic changes in the murine adrenal cortex.
Volume: 29
Issue: 7
Pages: 2930-42
Publication
First Author: Cooray SN
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses.
Volume: 110
Issue: 45
Pages: 18232-7
Publication
First Author: Migeotte I
Year: 2006
Journal: Cytokine Growth Factor Rev
Title: Formyl peptide receptors: a promiscuous subfamily of G protein-coupled receptors controlling immune responses.
Volume: 17
Issue: 6
Pages: 501-19
Publication
First Author: Ye RD
Year: 2009
Journal: Pharmacol Rev
Title: International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family.
Volume: 61
Issue: 2
Pages: 119-61
Publication
First Author: Le Y
Year: 2002
Journal: Trends Immunol
Title: Formyl-peptide receptors revisited.
Volume: 23
Issue: 11
Pages: 541-8
Publication
First Author: Panaro MA
Year: 2006
Journal: Immunopharmacol Immunotoxicol
Title: Biological role of the N-formyl peptide receptors.
Volume: 28
Issue: 1
Pages: 103-27
Publication
First Author: Braun MC
Year: 2001
Journal: Blood
Title: Activation of the formyl peptide receptor by the HIV-derived peptide T-20 suppresses interleukin-12 p70 production by human monocytes.
Volume: 97
Issue: 11
Pages: 3531-6
Publication
First Author: He HQ
Year: 2013
Journal: Mol Pharmacol
Title: Functional characterization of three mouse formyl peptide receptors.
Volume: 83
Issue: 2
Pages: 389-98
Publication
First Author: Fu H
Year: 2006
Journal: J Leukoc Biol
Title: Ligand recognition and activation of formyl peptide receptors in neutrophils.
Volume: 79
Issue: 2
Pages: 247-56
Publication  
First Author: Fanghänel J
Year: 2004
Journal: Front Biosci
Title: Insights into the catalytic mechanism of peptidyl prolyl cis/trans isomerases.
Volume: 9
Pages: 3453-78
Publication
First Author: Li H
Year: 2010
Journal: Cell Res
Title: AtFKBP53 is a histone chaperone required for repression of ribosomal RNA gene expression in Arabidopsis.
Volume: 20
Issue: 3
Pages: 357-66
Publication
First Author: Kuzuhara T
Year: 2004
Journal: Nat Struct Mol Biol
Title: A nuclear FK506-binding protein is a histone chaperone regulating rDNA silencing.
Volume: 11
Issue: 3
Pages: 275-83
Protein Domain
Type: Family
Description: FK506-binding proteins (FKBPs) are a particular class of peptidyl-prolyl cis-trans isomerases (PPIases) () []. This entry represents a group of nuclear FK506-binding proteins that act as histone chaperones. They each containing an extended acidic domain in addition to the conserved FK506-binding/peptidylprolyl isomerase (PPIase) domain. The PPIase domain has been shown to regulate histone H3 methylation, while the acidic domain has been shown to facilitate histone deposition and may regulate rDNA silencing [, ]. This entry includes Fpr3 and its paralogue, Fpr4, from budding yeasts. They have been shown to affect genome-wide genes transcription [].This entry also includes AtFKBP53 from Arabidopsis and SpFkbp39p from Schizosaccharomyces pombe. AtFKBP53 possesses histone chaperone activity and is required for repressing ribosomal gene expression in Arabidopsis []. SpFkbp39p is a histone chaperone regulating rDNA silencing [].
Publication
First Author: Crass T
Year: 1996
Journal: Eur J Immunol
Title: Expression cloning of the human C3a anaphylatoxin receptor (C3aR) from differentiated U-937 cells.
Volume: 26
Issue: 8
Pages: 1944-50
Publication
First Author: Su SB
Year: 1999
Journal: J Exp Med
Title: A seven-transmembrane, G protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells.
Volume: 189
Issue: 2
Pages: 395-402
Publication
First Author: Gao JL
Year: 1999
Journal: J Exp Med
Title: Impaired antibacterial host defense in mice lacking the N-formylpeptide receptor.
Volume: 189
Issue: 4
Pages: 657-62
Publication
First Author: Schiffmann E
Year: 1975
Journal: Proc Natl Acad Sci U S A
Title: N-formylmethionyl peptides as chemoattractants for leucocytes.
Volume: 72
Issue: 3
Pages: 1059-62
Publication
First Author: Kindzelskii AL
Year: 1994
Journal: J Struct Biol
Title: Imaging the spatial distribution of membrane receptors during neutrophil phagocytosis.
Volume: 113
Issue: 3
Pages: 191-8
Publication
First Author: Schepetkin IA
Year: 2008
Journal: Mol Pharmacol
Title: Identification of novel formyl peptide receptor-like 1 agonists that induce macrophage tumor necrosis factor alpha production.
Volume: 74
Issue: 2
Pages: 392-402
Publication
First Author: Browning DD
Year: 1997
Journal: J Biol Chem
Title: Cell type- and developmental stage-specific activation of NF-kappaB by fMet-Leu-Phe in myeloid cells.
Volume: 272
Issue: 12
Pages: 7995-8001
Publication
First Author: Zhou Y
Year: 2005
Journal: J Natl Cancer Inst
Title: Formylpeptide receptor FPR and the rapid growth of malignant human gliomas.
Volume: 97
Issue: 11
Pages: 823-35
Publication
First Author: Chen DL
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Downregulating FPR restrains xenograft tumors by impairing the angiogenic potential and invasive capability of malignant glioma cells.
Volume: 381
Issue: 3
Pages: 448-52
Publication
First Author: Karlsson J
Year: 2005
Journal: J Leukoc Biol
Title: Neutrophil NADPH-oxidase activation by an annexin AI peptide is transduced by the formyl peptide receptor (FPR), whereas an inhibitory signal is generated independently of the FPR family receptors.
Volume: 78
Issue: 3
Pages: 762-71