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Search results 1 to 56 out of 56 for Fsbp

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
100861412 | FSBP
Type: gene
Organism: human
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Gene
100614373 | FSBP
Type: gene
Organism: chimpanzee
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Gene
100848732 | FSBP
Type: gene
Organism: cattle
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Gene
770634 | FSBP
Type: gene
Organism: chicken
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Gene
100429533 | FSBP
Type: gene
Organism: macaque, rhesus
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Gene
101884826 | fsbp
Type: gene
Organism: zebrafish
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Gene
102152707 | FSBP
Type: gene
Organism: dog, domestic
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Gene
102550523 | Fsbp
Type: gene
Organism: rat
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Gene
101733687 | fsbp
Type: gene
Organism: frog, western clawed
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Protein Coding Gene
MGI:5301008 | Fsbp
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR042383 | FSBP
Type: Family
Description: Fibrinogen silencer-binding protein (FSBP) is a transcription factor that interacts with the neuronal adaptor protein X11alpha. The X11alpha/FSBP complex has been shown to signal to the nucleus to repress glycogen synthase kinase-3beta promoter activity [].
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Publication
20531236 | -
First Author: Lau KF
Year: 2010
Journal: Neuroreport
Title: An X11alpha/FSBP complex represses transcription of the GSK3beta gene promoter.
Volume: 21
Issue: 11
Pages: 761-6
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Protein
Q8BKE5
Organism: Mus musculus/domesticus
Length: 299  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0025811 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028055 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028012 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0027978 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028024 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027754 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_5301008 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028467 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027208 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027729 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027870 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027836 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0027980 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027869 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028526 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0026929 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027287 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023934 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026759 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
- | J:193309
       
First Author: Mouse Genome Informatics Scientfic Curators
Year: 2013
Title: Curated associations of genes in MGI and UniProt sequence records
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
9753324 | J:49850
First Author: Butz S
Year: 1998
Journal: Cell
Title: A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.
Volume: 94
Issue: 6
Pages: 773-82
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Publication
20378958 | -
First Author: Mitchell JC
Year: 2010
Journal: J Alzheimers Dis
Title: Expression of the neuronal adaptor protein X11alpha protects against memory dysfunction in a transgenic mouse model of Alzheimer's disease.
Volume: 20
Issue: 1
Pages: 31-6
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Publication
12970358 | -
First Author: Lee JH
Year: 2003
Journal: J Biol Chem
Title: The neuronal adaptor protein X11alpha reduces Abeta levels in the brains of Alzheimer's APPswe Tg2576 transgenic mice.
Volume: 278
Issue: 47
Pages: 47025-9
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Publication
9952408 | -
First Author: Borg JP
Year: 1999
Journal: J Neurosci
Title: Molecular analysis of the X11-mLin-2/CASK complex in brain.
Volume: 19
Issue: 4
Pages: 1307-16
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Protein Domain
IPR030530 | Apba1
Type: Family
Description: Amyloid beta A4 precursor protein-binding family A member 1, also known as Mint1 or X11alpha, is a neuronal adaptor protein that binds to the intracellular domain of the amyloid precursor protein (APP) []. It belongs to the X11/Mint family of adaptor proteins []. It has been shown to modulate processing of APP and accumulation of Abeta (hallmark pathologies of Alzheimer's disease), making it a potential therapeutic target for Alzheimer's disease []. It may also affect Alzheimer's disease pathogenesis through its interaction with transcription factor FSBP (fibrinogen silencer binding protein), forming a complex that represses glycogen synthase kinase-3beta (GSK3beta) transcription. GSK3beta is a candidate kinase for the phosphorylation of tau in Alzheimer's disease [].X11alpha participates in a brain-specific heterotrimeric complex containing two other PDZ domain proteins, Lin-2/CASK and mLin-7, involved in synaptic vesicle exocytosis and synaptic junctions []. Additional proteins can bind, forming a neuronal multiprotein complex predicted to be involved in receptor localisation []. The X11/Mint family members are multidomain proteins typically composed of a conserved PTB domain and two C-terminal PDZ domains. They are adaptor proteins that possess several functions, such as trafficking and transport, synaptic function and regulation of ion channel []. Two of the family members, X11alpha and X11beta, are expressed primarily in neurones [].
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Publication
16764936 | -
First Author: Rogelj B
Year: 2006
Journal: Brain Res Rev
Title: The X11/Mint family of adaptor proteins.
Volume: 52
Issue: 2
Pages: 305-15
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Protein
B2RUJ5
Organism: Mus musculus/domesticus
Length: 842  
Fragment?: false
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Protein
Q3UH26
Organism: Mus musculus/domesticus
Length: 843  
Fragment?: false
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