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Search results 1 to 90 out of 90 for Fscb

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Hits by Category

Hits by Strain

Type Details Score
Gene
84075 | FSCB
Type: gene
Organism: human
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Gene
500659 | Fscb
Type: gene
Organism: rat
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Gene
467442 | FSCB
Type: gene
Organism: chimpanzee
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Gene
767821 | FSCB
Type: gene
Organism: cattle
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Gene
100684231 | FSCB
Type: gene
Organism: dog, domestic
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Gene
701592 | FSCB
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR043375 | FSCB
Type: Family
Description: Fibrous sheath CABYR (Calcium Binding Tyrosine-(Y)-Phosphorylation Regulated) binding protein (FSCB) is a testis- and sperm-specific protein that is expressed post-meiotically and localised in mouse sperm flagella. FSCB homologues are present in other mammals, including rat and human. Conserved motifs in FSCB include PXXP, proline-rich and extensin-like regions [].FSCB is regulated by protein kinase A (PKA)-mediated tryrosine phosphorylation. Its capacity of being phosphorylated and binding to calcium enhances the spermatozoa flagellar movement, spermatozoa capacitation and activation. FSCB phosphorylation activates spermatozoa motility and inhibits SUMOylation of two crucial proteins ROPN1/ROPN1L that are associated with PKA/A kinase activity and spermatozoa motility [].
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Protein Coding Gene
MGI:3646964 | Fscb
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
27398160 | J:243457
First Author: Zhang X
Year: 2016
Journal: Am J Transl Res
Title: FSCB phosphorylation regulates mouse spermatozoa capacitation through suppressing SUMOylation of ROPN1/ROPN1L.
Volume: 8
Issue: 6
Pages: 2776-82
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Publication
17855365 | J:128382
First Author: Li YF
Year: 2007
Journal: J Biol Chem
Title: FSCB, a novel protein kinase A-phosphorylated calcium-binding protein, is a CABYR-binding partner involved in late steps of fibrous sheath biogenesis.
Volume: 282
Issue: 47
Pages: 34104-19
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Protein
A1EGX6
Organism: Mus musculus/domesticus
Length: 1074  
Fragment?: false
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Protein
E9QJV1
Organism: Mus musculus/domesticus
Length: 1062  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0017785 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019774 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019733 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019708 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019713 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019518 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3646964 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020165 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019070 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019487 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019603 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019591 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019675 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019629 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020199 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018836 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019121 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029541 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018630 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:5649230
Assay Type: Northern blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5649233
Age: postnatal adult
Image: 4
Specimen Label: heart
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5649230
Assay Type: Northern blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5649233
Age: postnatal adult
Image: 4
Specimen Label: brain
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5649230
Assay Type: Northern blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5649233
Age: postnatal adult
Image: 4
Specimen Label: spleen
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5649230
Assay Type: Northern blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5649233
Age: postnatal adult
Image: 4
Specimen Label: lung
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5649230
Assay Type: Northern blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5649233
Age: postnatal adult
Image: 4
Specimen Label: liver
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5649230
Assay Type: Northern blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:5649233
Age: postnatal adult
Image: 4
Specimen Label: skeletal muscle
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5649230
Assay Type: Northern blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5649233
Age: postnatal adult
Image: 4
Specimen Label: kidney
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:5649230
Assay Type: Northern blot
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5649233
Age: postnatal adult
Image: 4
Specimen Label: testis
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148828
Stage: TS28
Assay Id: MGI:5649234
Age: postnatal adult
Image: 5
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: brain
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: heart
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: kidney
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: liver
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: lung
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: ovary
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: skeletal muscle
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: skin
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: spleen
Detected: false
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: testis
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: thymus
Detected: false
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Western blot
Annotation Date: 2015-08-19
Strength: Absent
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:5649235
Age: postnatal
Image: 6
Specimen Label: uterus
Detected: false
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:1929228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 8/A
Specimen Label: 8/A
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:1929328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Note: Expression is present in sperm located in the lumen of the epididymal duct.
Specimen Label: not shown
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Absent
Sex: Male
Emaps: EMAPS:3044528
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 8/A
Specimen Label: 8/A
Detected: false
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Absent
Sex: Male
Emaps: EMAPS:3148628
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7A
Note: No expression in round or elongating spermatids.
Specimen Label: 7A
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Pattern: Diffuse
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7B
Note: Expression present in elongating spermatids.
Specimen Label: 7B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7C
Specimen Label: 7C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7D
Specimen Label: 7D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7E
Specimen Label: 7E
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:1929128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Note: Expression is present in sperm located in the lumen of the epididymal duct.
Specimen Label: not shown
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Absent
Sex: Male
Emaps: EMAPS:3576128
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7A
Note: No expression in round or elongating spermatids.
Specimen Label: 7A
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3576128
Pattern: Diffuse
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7B
Note: Expression present in elongating spermatids.
Specimen Label: 7B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3576128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7C
Specimen Label: 7C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3576128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7D
Specimen Label: 7D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3576128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7E
Specimen Label: 7E
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3576128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7F
Specimen Label: 7F
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3576128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7G
Specimen Label: 7G
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3576128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7H
Note: Expression is present in the testicular sperm, present at the luminal surface of the seminiferous epithelium. It is not present in cells located apically in the seminiferous epithelium.
Specimen Label: 7H
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7F
Specimen Label: 7F
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7G
Specimen Label: 7G
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Male
Emaps: EMAPS:3148828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 7H
Note: Expression is present in the testicular sperm, present at the luminal surface of the seminiferous epithelium. It is not present in cells located apically in the seminiferous epithelium.
Specimen Label: 7H
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:5649232
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Strong
Sex: Male
Emaps: EMAPS:3148828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649236
Age: postnatal adult
Image: 8/A
Note: Expression is present in sperm located in the lumen of the epididymal duct.
Specimen Label: 8/A
Detected: true
Specimen Num: 9
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Publication
32588039 | J:293870
First Author: Sun J
Year: 2020
Journal: Biol Reprod
Title: CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction†.
Volume: 103
Issue: 2
Pages: 183-194
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
38355793 | J:345621
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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