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Search results 1 to 100 out of 467 for Fscn1

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0.055s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Fascins are actin cross-linking proteins that function in the organisation of two major forms of actin-based structures: dynamic, cortical cell protrusions and cytoplasmic microfilament bundles [].In humans there are three fascin isoforms identified: fascin1-3. Fruit flies only have one fascin, also known as protein singed, which links Btl/FGFR signalling to the actin cytoskeleton during Drosophila tracheal morphogenesis [].This entry represents fascin-1 (FSCN1) from mammals and its homologues from Xenopus laevis and Drosophila melanogaster. FSCN1 plays a role in stress fibre organisation and focal adhesion disassembly []. In humans, FSCN1 serves as a tumour marker that is highly expressed in numerous types of cancer, including lymphomas. It is important for migration and metastasis of tumour cells [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication  
First Author: Kashgari G
Year: 2021
Journal: JCI Insight
Title: GRHL3 activates FSCN1 to relax cell-cell adhesions between migrating keratinocytes during wound reepithelialization.
Volume: 6
Issue: 17
Publication
First Author: Elkhatib N
Year: 2014
Journal: Curr Biol
Title: Fascin plays a role in stress fiber organization and focal adhesion disassembly.
Volume: 24
Issue: 13
Pages: 1492-9
Publication  
First Author: Mohr CF
Year: 2014
Journal: Cell Commun Signal
Title: The tumor marker Fascin is induced by the Epstein-Barr virus-encoded oncoprotein LMP1 via NF-κB in lymphocytes and contributes to their invasive migration.
Volume: 12
Pages: 46
Publication
First Author: Okenve-Ramos P
Year: 2014
Journal: Development
Title: Fascin links Btl/FGFR signalling to the actin cytoskeleton during Drosophila tracheal morphogenesis.
Volume: 141
Issue: 4
Pages: 929-39
Protein
Organism: Mus musculus/domesticus
Length: 241  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 332  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
Publication
First Author: Kureishy N
Year: 2002
Journal: Bioessays
Title: Fascins, and their roles in cell structure and function.
Volume: 24
Issue: 4
Pages: 350-61
Publication
First Author: Tubb BE
Year: 2000
Journal: Genomics
Title: Characterization of human retinal fascin gene (FSCN2) at 17q25: close physical linkage of fascin and cytoplasmic actin genes.
Volume: 65
Issue: 2
Pages: 146-56
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Chen L
Year: 2010
Journal: Nature
Title: Migrastatin analogues target fascin to block tumour metastasis.
Volume: 464
Issue: 7291
Pages: 1062-6
Publication
First Author: Jansen S
Year: 2011
Journal: J Biol Chem
Title: Mechanism of actin filament bundling by fascin.
Volume: 286
Issue: 34
Pages: 30087-96
Publication
First Author: Matsumura F
Year: 2013
Journal: J Immunol
Title: Fascin confers resistance to Listeria infection in dendritic cells.
Volume: 191
Issue: 12
Pages: 6156-64
Publication  
First Author: Al-Khaldi S
Year: 2022
Journal: Dev Biol
Title: Fascin is essential for mammary gland lactogenesis.
Volume: 492
Pages: 25-36
Publication
First Author: Sonego M
Year: 2013
Journal: J Neurosci
Title: Fascin regulates the migration of subventricular zone-derived neuroblasts in the postnatal brain.
Volume: 33
Issue: 30
Pages: 12171-85
Publication
First Author: Yamakita Y
Year: 2011
Journal: J Immunol
Title: Fascin1 promotes cell migration of mature dendritic cells.
Volume: 186
Issue: 5
Pages: 2850-9
Publication
First Author: Aratyn YS
Year: 2007
Journal: Mol Biol Cell
Title: Intrinsic dynamic behavior of fascin in filopodia.
Volume: 18
Issue: 10
Pages: 3928-40
Publication
First Author: Mavrakis M
Year: 2014
Journal: Nat Cell Biol
Title: Septins promote F-actin ring formation by crosslinking actin filaments into curved bundles.
Volume: 16
Issue: 4
Pages: 322-34
Publication
First Author: Shonukan O
Year: 2003
Journal: Oncogene
Title: Neurotrophin-induced melanoma cell migration is mediated through the actin-bundling protein fascin.
Volume: 22
Issue: 23
Pages: 3616-23
Publication
First Author: Vignjevic D
Year: 2006
Journal: J Cell Biol
Title: Role of fascin in filopodial protrusion.
Volume: 174
Issue: 6
Pages: 863-75
Publication
First Author: Chae JI
Year: 2009
Journal: Proteomics
Title: Cytoskeleton-associated proteins are enriched in human embryonic-stem cell-derived neuroectodermal spheres.
Volume: 9
Issue: 5
Pages: 1128-41
Publication
First Author: Chittiprol S
Year: 2011
Journal: Am J Physiol Renal Physiol
Title: Marker expression, behaviors, and responses vary in different lines of conditionally immortalized cultured podocytes.
Volume: 301
Issue: 3
Pages: F660-71
Publication
First Author: Kliewe F
Year: 2017
Journal: Sci Rep
Title: Studying the role of fascin-1 in mechanically stressed podocytes.
Volume: 7
Issue: 1
Pages: 9916
GXD Expression    
Probe: MGI:3800425
Assay Type: Western blot
Annotation Date: 2008-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3800433
Age: postnatal adult
Image: 1
Specimen Label: BRAIN
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3800425
Assay Type: Western blot
Annotation Date: 2008-08-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3800433
Age: postnatal adult
Image: 1
Specimen Label: HEART
Specimen Num: 2
GXD Expression      
Probe: MGI:3800425
Assay Type: Western blot
Annotation Date: 2008-08-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3800433
Age: postnatal adult
Image: 1
Specimen Label: LUNG
Specimen Num: 3
GXD Expression    
Probe: MGI:3800425
Assay Type: Western blot
Annotation Date: 2008-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3800433
Age: postnatal adult
Image: 1
Specimen Label: SPLEEN
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3800425
Assay Type: Western blot
Annotation Date: 2008-08-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3800433
Age: postnatal adult
Image: 1
Specimen Label: LIVER
Specimen Num: 5
GXD Expression      
Probe: MGI:3800425
Assay Type: Western blot
Annotation Date: 2008-08-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3800433
Age: postnatal adult
Image: 1
Specimen Label: KIDNEY
Specimen Num: 6
GXD Expression    
Probe: MGI:3800425
Assay Type: Western blot
Annotation Date: 2008-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:3800433
Age: postnatal adult
Image: 1
Specimen Label: S. INT.
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3800425
Assay Type: Western blot
Annotation Date: 2008-08-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1925228
Stage: TS28
Assay Id: MGI:3800433
Age: postnatal adult
Image: 1
Specimen Label: L. INT.
Specimen Num: 8
GXD Expression    
Probe: MGI:3800425
Assay Type: Western blot
Annotation Date: 2008-08-05
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:3800433
Age: postnatal adult
Image: 1
Specimen Label: UTERUS
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:3800423
Assay Type: Northern blot
Annotation Date: 2008-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3800436
Age: postnatal adult
Specimen Label: not shown
Detected: true
Specimen Num: 1
GXD Expression        
Probe: MGI:3800423
Assay Type: Northern blot
Annotation Date: 2008-08-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3800436
Age: postnatal adult
Specimen Label: not shown
Specimen Num: 2
GXD Expression        
Probe: MGI:3800423
Assay Type: Northern blot
Annotation Date: 2008-08-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3800436
Age: postnatal adult
Specimen Label: not shown
Specimen Num: 3
GXD Expression        
Probe: MGI:3800423
Assay Type: Northern blot
Annotation Date: 2008-08-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3800436
Age: postnatal adult
Specimen Label: not shown
Specimen Num: 4
GXD Expression        
Probe: MGI:3800423
Assay Type: Northern blot
Annotation Date: 2008-08-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3800436
Age: postnatal adult
Specimen Label: not shown
Specimen Num: 5
GXD Expression        
Probe: MGI:3800423
Assay Type: Northern blot
Annotation Date: 2008-08-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3800436
Age: postnatal adult
Specimen Label: not shown
Specimen Num: 6
GXD Expression        
Probe: MGI:3800423
Assay Type: Northern blot
Annotation Date: 2008-08-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:3800436
Age: postnatal adult
Specimen Label: not shown
Specimen Num: 7
GXD Expression        
Probe: MGI:3800423
Assay Type: Northern blot
Annotation Date: 2008-08-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1925228
Stage: TS28
Assay Id: MGI:3800436
Age: postnatal adult
Specimen Label: not shown
Specimen Num: 8
GXD Expression        
Probe: MGI:3800423
Assay Type: Northern blot
Annotation Date: 2008-08-05
Strength: Not Specified
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:3800436
Age: postnatal adult
Specimen Label: not shown
Specimen Num: 9
GXD Expression      
Probe: MGI:5621135
Assay Type: Western blot
Annotation Date: 2015-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5621141
Age: postnatal adult
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5621135
Assay Type: Western blot
Annotation Date: 2015-04-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5621141
Age: postnatal adult
Specimen Label: 3
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:5621135
Assay Type: Western blot
Annotation Date: 2015-04-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5621141
Age: postnatal adult
Specimen Label: 4
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:5621135
Assay Type: Western blot
Annotation Date: 2015-04-08
Strength: Absent
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:5621141
Age: postnatal adult
Specimen Label: 6
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:5621135
Assay Type: Western blot
Annotation Date: 2015-04-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5621141
Age: postnatal adult
Specimen Label: 7
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:5621136
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5621142
Age: postnatal adult
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5621136
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5621142
Age: postnatal adult
Specimen Label: 4
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:5621136
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:5621142
Age: postnatal adult
Specimen Label: 7
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5621136
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:5621142
Age: postnatal adult
Specimen Label: 10
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:5621136
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5621142
Age: postnatal adult
Specimen Label: 13
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5621136
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5621142
Age: postnatal adult
Specimen Label: 16
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:5621136
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:5621142
Age: embryonic day 16.0
Specimen Label: 19
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5621136
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:5621142
Age: embryonic day 16.0
Specimen Label: 22
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:5816564
Assay Type: Western blot
Annotation Date: 2017-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:5816596
Age: embryonic day 13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5816564
Assay Type: Western blot
Annotation Date: 2017-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:5816596
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5816564
Assay Type: Western blot
Annotation Date: 2017-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:5816596
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5816564
Assay Type: Western blot
Annotation Date: 2017-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5816596
Age: postnatal day 4
Specimen Label: P4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5816564
Assay Type: Western blot
Annotation Date: 2017-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5816596
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5816564
Assay Type: Western blot
Annotation Date: 2017-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5816596
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6444163
Assay Type: RT-PCR
Annotation Date: 2020-07-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603914
Stage: TS14
Assay Id: MGI:6444175
Age: embryonic day 8.75-9.0
Image: 4
Specimen Label: Control
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6444163
Assay Type: RT-PCR
Annotation Date: 2020-07-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603914
Stage: TS14
Assay Id: MGI:6444175
Age: embryonic day 8.75-9.0
Image: 4
Specimen Label: Srf flex1/flex1; T(s)::Cre
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3526169
Assay Type: RNA in situ
Annotation Date: 2005-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3526174
Age: embryonic day 9.5
Image: 1C
Specimen Label: 1C
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3526169
Assay Type: RNA in situ
Annotation Date: 2005-02-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1611817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3526174
Age: embryonic day 10.5
Image: 1G
Specimen Label: 1G
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3526169
Assay Type: RNA in situ
Annotation Date: 2005-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1667820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:3526175
Age: embryonic day 12.5
Note: Expression is in the optic nerve.
Specimen Label: Table 1
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:3843514
Assay Type: Immunohistochemistry
Annotation Date: 2009-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3843516
Age: embryonic day 15.5
Note: Expression mainly in the subventricular/ventricular zone.
Specimen Label: 6d
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3526169
Assay Type: RNA in situ
Annotation Date: 2005-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3526175
Age: embryonic day 12.5
Specimen Label: Table 1
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:3526169
Assay Type: RNA in situ
Annotation Date: 2005-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3526175
Age: embryonic day 14.5
Specimen Label: Table 1
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:3526169
Assay Type: RNA in situ
Annotation Date: 2005-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3526174
Age: embryonic day 10.5
Image: 1G
Specimen Label: 1G
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3526169
Assay Type: RNA in situ
Annotation Date: 2005-02-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3526175
Age: embryonic day 10.5
Specimen Label: Table 1
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:3526169
Assay Type: RNA in situ
Annotation Date: 2005-02-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691620
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3526175
Age: embryonic day 12.5
Specimen Label: Table 1
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:3526169
Assay Type: RNA in situ
Annotation Date: 2005-02-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3526175
Age: embryonic day 14.5
Specimen Label: Table 1
Detected: true
Specimen Num: 16