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Search results 1 to 94 out of 94 for Fscn2

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Hits by Category

Hits by Strain

Type Details Score
Gene
25794 | FSCN2
Type: gene
Organism: human
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Gene
100101745 | fscn2
Type: gene
Organism: frog, western clawed
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Gene
337926 | FSCN2
Type: gene
Organism: cattle
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Gene
107973378 | FSCN2
Type: gene
Organism: chimpanzee
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Gene
303741 | Fscn2
Type: gene
Organism: rat
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Gene
483362 | FSCN2
Type: gene
Organism: dog, domestic
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Gene
429198 | FSCN2
Type: gene
Organism: chicken
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Gene
713824 | FSCN2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2443337 | Fscn2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR030144 | FSCN2
Type: Family
Description: Fascins are actin cross-linking proteins that function in the organisation of two major forms of actin-based structures: dynamic, cortical cell protrusions and cytoplasmic microfilament bundles [].This entry represents fascin-2 (FSCN2), which cooperates with beta-actin to maintain the stereocilia length. Stereocilia are actin-based protrusions on auditory sensory hair cells [].
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Publication
23658152 | J:197137
First Author: Perrin BJ
Year: 2013
Journal: J Neurosci
Title: β-Actin and fascin-2 cooperate to maintain stereocilia length.
Volume: 33
Issue: 19
Pages: 8114-21
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Publication
16043865 | J:103713
First Author: Yokokura S
Year: 2005
Journal: Invest Ophthalmol Vis Sci
Title: Targeted disruption of FSCN2 gene induces retinopathy in mice.
Volume: 46
Issue: 8
Pages: 2905-15
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Publication
26092689 | J:227315
First Author: Johnson KR
Year: 2015
Journal: Mamm Genome
Title: A QTL on Chr 5 modifies hearing loss associated with the fascin-2 variant of DBA/2J mice.
Volume: 26
Issue: 7-8
Pages: 338-47
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Protein
Q32M02
Organism: Mus musculus/domesticus
Length: 492  
Fragment?: false
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Publication
11948621 | -
First Author: Kureishy N
Year: 2002
Journal: Bioessays
Title: Fascins, and their roles in cell structure and function.
Volume: 24
Issue: 4
Pages: 350-61
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Publication
20660251 | J:162868
First Author: Shin JB
Year: 2010
Journal: J Neurosci
Title: The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice.
Volume: 30
Issue: 29
Pages: 9683-94
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QTL
MGI:5828283 | M1fscn2
Type: QTL
Organism: mouse, laboratory
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QTL
MGI:5828286 | M2fscn2
Type: QTL
Organism: mouse, laboratory
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QTL
MGI:5828290 | M3fscn2
Type: QTL
Organism: mouse, laboratory
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Publication
30082328 | J:274170
First Author: Liu X
Year: 2018
Journal: G3 (Bethesda)
Title: Null Mutation of the Fascin2 Gene by TALEN Leading to Progressive Hearing Loss and Retinal Degeneration in C57BL/6J Mice.
Volume: 8
Issue: 10
Pages: 3221-3230
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Protein Coding Gene
MGP_CAROLIEiJ_G0017513 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019496 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019464 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019434 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019439 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019245 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2443337 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019887 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018799 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019216 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019328 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019320 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019400 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019353 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019927 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018565 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018851 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018639 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018357 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:5621137
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5621143
Age: postnatal adult
Specimen Label: 2
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5621137
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5621143
Age: postnatal adult
Specimen Label: 5
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5621137
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:5621143
Age: postnatal adult
Specimen Label: 8
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5621137
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:5621143
Age: postnatal adult
Specimen Label: 11
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5621137
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5621143
Age: postnatal adult
Specimen Label: 14
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5621137
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5621143
Age: postnatal adult
Specimen Label: 17
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:5621137
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:5621143
Age: embryonic day 16.0
Specimen Label: 20
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:5621137
Assay Type: RT-PCR
Annotation Date: 2015-04-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:5621143
Age: embryonic day 16.0
Specimen Label: 23
Detected: false
Specimen Num: 8
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Publication
27811163 | J:242628
First Author: Krey JF
Year: 2016
Journal: J Cell Biol
Title: Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid.
Volume: 215
Issue: 4
Pages: 467-482
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Publication
18662770 | J:139223
First Author: Johnson KR
Year: 2008
Journal: Genomics
Title: A locus on distal chromosome 11 (ahl8) and its interaction with Cdh23 ahl underlie the early onset, age-related hearing loss of DBA/2J mice.
Volume: 92
Issue: 4
Pages: 219-25
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Publication
28345280 | J:267808
First Author: Wang Q
Year: 2017
Journal: J Neurosci Res
Title: Otoprotective effects of mouse nerve growth factor in DBA/2J mice with early-onset progressive hearing loss.
Volume: 95
Issue: 10
Pages: 1937-1950
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Publication
23850281 | J:199812
First Author: Jaiswal R
Year: 2013
Journal: Curr Biol
Title: The formin Daam1 and fascin directly collaborate to promote filopodia formation.
Volume: 23
Issue: 14
Pages: 1373-9
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Publication
19343791 | J:205179
First Author: Yamakita Y
Year: 2009
Journal: Cell Motil Cytoskeleton
Title: Fascin1 is dispensable for mouse development but is favorable for neonatal survival.
Volume: 66
Issue: 8
Pages: 524-34
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Publication
25765874 | J:248161
First Author: Suzuki S
Year: 2015
Journal: Exp Anim
Title: Quantitative trait loci on chromosome 5 for susceptibility to frequency-specific effects on hearing in DBA/2J mice.
Volume: 64
Issue: 3
Pages: 241-51
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Publication
25757744 | J:230346
First Author: Omori Y
Year: 2015
Journal: Genes Cells
Title: Mef2d is essential for the maturation and integrity of retinal photoreceptor and bipolar cells.
Volume: 20
Issue: 5
Pages: 408-26
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Publication
32290105 | J:282558
 
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Fscn2<tm1Sykk> | MGI:3612337
Name: fascin actin-bundling protein 2; targeted mutation 1, Shunji Yokokura
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Fscn2<tm2Sykk> | MGI:3612338
Name: fascin actin-bundling protein 2; targeted mutation 2, Shinji Yokokura
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Fscn2/Fscn2<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fscn2/Fscn2<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0110406 | retinitis pigmentosa 30
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Allele
Tg(RP24-180N9)1Kjn | MGI:4821953
Name: transgene insertion 1, Kenneth R Johnson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(RP24-180N9)2Kjn | MGI:4821955
Name: transgene insertion 2, Kenneth R Johnson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:4821965 | DBA/2J-Tg(RP24-180N9)2Kjn/Kjn
Attribute String: coisogenic, mutant strain, transgenic
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Genotype
Genotype
Symbol: Tg(RP24-180N9)2Kjn/?
Background: DBA/2J-Tg(RP24-180N9)2Kjn/Kjn
Zygosity: ot
Has Mutant Allele: true
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Publication
10783262 | J:62105
First Author: Tubb BE
Year: 2000
Journal: Genomics
Title: Characterization of human retinal fascin gene (FSCN2) at 17q25: close physical linkage of fascin and cytoplasmic actin genes.
Volume: 65
Issue: 2
Pages: 146-56
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Publication
28216641 | J:276108
 
First Author: Lv JN
Year: 2017
Journal: Sci Rep
Title: Targeted RP9 ablation and mutagenesis in mouse photoreceptor cells by CRISPR-Cas9.
Volume: 7
Pages: 43062
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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