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Search results 1 to 100 out of 645 for Furin

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein
Organism: Mus musculus
Length: 793  
Fragment?: false
Protein
Organism: Mus musculus
Length: 252  
Fragment?: true
Protein
Organism: Mus musculus
Length: 43  
Fragment?: true
Protein
Organism: Mus musculus
Length: 59  
Fragment?: true
Protein
Organism: Mus musculus
Length: 70  
Fragment?: true
Publication
First Author: Hatsuzawa K
Year: 1990
Journal: J Biol Chem
Title: Structure and expression of mouse furin, a yeast Kex2-related protease. Lack of processing of coexpressed prorenin in GH4C1 cells.
Volume: 265
Issue: 36
Pages: 22075-8
Publication
First Author: Liu G
Year: 1997
Journal: J Cell Biol
Title: Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.
Volume: 139
Issue: 7
Pages: 1719-33
Publication
First Author: Ortutay Z
Year: 2015
Journal: J Leukoc Biol
Title: Proprotein convertase FURIN regulates T cell receptor-induced transactivation.
Volume: 98
Issue: 1
Pages: 73-83
Publication
First Author: Roebroek AJ
Year: 2004
Journal: J Biol Chem
Title: Limited redundancy of the proprotein convertase furin in mouse liver.
Volume: 279
Issue: 51
Pages: 53442-50
Publication
First Author: Pesu M
Year: 2008
Journal: Nature
Title: T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance.
Volume: 455
Issue: 7210
Pages: 246-50
Publication
First Author: Kim W
Year: 2012
Journal: Mol Cell Biol
Title: Loss of endothelial furin leads to cardiac malformation and early postnatal death.
Volume: 32
Issue: 17
Pages: 3382-91
Publication  
First Author: He Z
Year: 2020
Journal: Cancer Lett
Title: Loss of the proprotein convertase Furin in T cells represses mammary tumorigenesis in oncogene-driven triple negative breast cancer.
Volume: 484
Pages: 40-49
Publication
First Author: Kayo T
Year: 1997
Journal: Diabetes
Title: Proprotein-processing endoprotease furin controls growth of pancreatic beta-cells.
Volume: 46
Issue: 8
Pages: 1296-304
Publication
First Author: Essalmani R
Year: 2011
Journal: J Biol Chem
Title: In vivo evidence that furin from hepatocytes inactivates PCSK9.
Volume: 286
Issue: 6
Pages: 4257-63
Publication
First Author: Meng TG
Year: 2017
Journal: Cell Death Dis
Title: Oocyte-specific deletion of furin leads to female infertility by causing early secondary follicle arrest in mice.
Volume: 8
Issue: 6
Pages: e2846
Publication
First Author: Al Rifai O
Year: 2017
Journal: J Clin Invest
Title: Proprotein convertase furin regulates osteocalcin and bone endocrine function.
Volume: 127
Issue: 11
Pages: 4104-4117
Publication
First Author: Thomas G
Year: 2002
Journal: Nat Rev Mol Cell Biol
Title: Furin at the cutting edge: from protein traffic to embryogenesis and disease.
Volume: 3
Issue: 10
Pages: 753-66
Publication
First Author: Louagie E
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate.
Volume: 105
Issue: 34
Pages: 12319-24
Publication
First Author: Farhadi H
Year: 1997
Journal: J Histochem Cytochem
Title: Prohormone convertases in mouse submandibular gland: co-localization of furin and nerve growth factor.
Volume: 45
Issue: 6
Pages: 795-804
Publication
First Author: Kayo T
Year: 1996
Journal: J Biol Chem
Title: Proprotein-processing endoprotease furin decreases regulated secretory pathway-specific proteins in the pancreatic beta cell line MIN6.
Volume: 271
Issue: 18
Pages: 10731-7
Publication
First Author: Li Y
Year: 2018
Journal: J Immunol
Title: STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells.
Volume: 201
Issue: 9
Pages: 2612-2623
Publication
First Author: Essalmani R
Year: 2013
Journal: J Biol Chem
Title: Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes.
Volume: 288
Issue: 37
Pages: 26410-8
Publication
First Author: Mesnard D
Year: 2011
Journal: Genes Dev
Title: The microenvironment patterns the pluripotent mouse epiblast through paracrine Furin and Pace4 proteolytic activities.
Volume: 25
Issue: 17
Pages: 1871-80
Publication
First Author: Bessonnard S
Year: 2015
Journal: J Cell Biol
Title: PC7 and the related proteases Furin and Pace4 regulate E-cadherin function during blastocyst formation.
Volume: 210
Issue: 7
Pages: 1185-97
Publication
First Author: Tellier E
Year: 2007
Journal: Mol Cell Biol
Title: Role for furin in tumor necrosis factor alpha-induced activation of the matrix metalloproteinase/sphingolipid mitogenic pathway.
Volume: 27
Issue: 8
Pages: 2997-3007
Publication
First Author: Blanchet MH
Year: 2008
Journal: EMBO J
Title: Cripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturation.
Volume: 27
Issue: 19
Pages: 2580-91
Publication
First Author: Torii S
Year: 1993
Journal: FEBS Lett
Title: Localization of Kex2-like processing endoproteases, furin and PC4, within mouse testis by in situ hybridization.
Volume: 316
Issue: 1
Pages: 12-6
Publication
First Author: Meyer A
Year: 1996
Journal: Brain Res
Title: Kainic acid increases the expression of the prohormone convertases furin and PC1 in the mouse hippocampus.
Volume: 732
Issue: 1-2
Pages: 121-32
Publication
First Author: Dey A
Year: 2004
Journal: Endocrinology
Title: Furin and prohormone convertase 1/3 are major convertases in the processing of mouse pro-growth hormone-releasing hormone.
Volume: 145
Issue: 4
Pages: 1961-71
Publication
First Author: Yakala GK
Year: 2019
Journal: Arterioscler Thromb Vasc Biol
Title: FURIN Inhibition Reduces Vascular Remodeling and Atherosclerotic Lesion Progression in Mice.
Volume: 39
Issue: 3
Pages: 387-401
Publication
First Author: Henrich S
Year: 2003
Journal: Nat Struct Biol
Title: The crystal structure of the proprotein processing proteinase furin explains its stringent specificity.
Volume: 10
Issue: 7
Pages: 520-6
Publication
First Author: Copeland NG
Year: 1992
Journal: Genomics
Title: Regional localization of three convertases, PC1 (Nec-1), PC2 (Nec-2), and furin (Fur), on mouse chromosomes.
Volume: 13
Issue: 4
Pages: 1356-8
Publication
First Author: Seidah NG
Year: 1991
Journal: Genomics
Title: Chromosomal assignments of the genes for neuroendocrine convertase PC1 (NEC1) to human 5q15-21, neuroendocrine convertase PC2 (NEC2) to human 20p11.1-11.2, and furin (mouse 7[D1-E2] region).
Volume: 11
Issue: 1
Pages: 103-7
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Drosophila melanogaster
Publication
First Author: De Vos L
Year: 2008
Journal: Int J Oncol
Title: MMTV-cre-mediated fur inactivation concomitant with PLAG1 proto-oncogene activation delays salivary gland tumorigenesis in mice.
Volume: 32
Issue: 5
Pages: 1073-83
Publication
First Author: Essalmani R
Year: 2017
Journal: J Biol Chem
Title: Thrombin activation of protein C requires prior processing by a liver proprotein convertase.
Volume: 292
Issue: 25
Pages: 10564-10573
Publication
First Author: Constam DB
Year: 2000
Journal: Development
Title: Tissue-specific requirements for the proprotein convertase furin/SPC1 during embryonic turning and heart looping.
Volume: 127
Issue: 2
Pages: 245-54
Publication
First Author: Robertson BJ
Year: 1993
Journal: J Biol Chem
Title: Defective processing of the insulin receptor in an endoprotease-deficient Chinese hamster cell strain is corrected by expression of mouse furin.
Volume: 268
Issue: 32
Pages: 24274-7
Publication
First Author: Roebroek AJ
Year: 1998
Journal: Development
Title: Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin.
Volume: 125
Issue: 24
Pages: 4863-76
Publication
First Author: Guzman-Ayala M
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment.
Volume: 101
Issue: 44
Pages: 15656-60
Publication
First Author: Mesnard D
Year: 2010
Journal: J Cell Biol
Title: Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst.
Volume: 191
Issue: 1
Pages: 129-39
Publication
First Author: Wetsel WC
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice.
Volume: 110
Issue: 43
Pages: 17362-7
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:4947662
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:4947685
Age: embryonic day 1.0
Image: 2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4947662
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:4947685
Age: embryonic day 2.0
Image: 2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6382692
Assay Type: RT-PCR
Annotation Date: 2019-12-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:6382723
Age: embryonic day 9.5
Image: 5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6382692
Assay Type: RT-PCR
Annotation Date: 2019-12-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608517
Stage: TS17
Assay Id: MGI:6382723
Age: embryonic day 10.5
Image: 5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6382692
Assay Type: RT-PCR
Annotation Date: 2019-12-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608517
Stage: TS17
Assay Id: MGI:6382723
Age: embryonic day 10.5
Image: 5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6382692
Assay Type: RT-PCR
Annotation Date: 2019-12-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:6382725
Age: embryonic day 9.5
Image: 7
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6382692
Assay Type: RT-PCR
Annotation Date: 2019-12-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608517
Stage: TS17
Assay Id: MGI:6382725
Age: embryonic day 10.5
Image: 7
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6382692
Assay Type: RT-PCR
Annotation Date: 2019-12-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608517
Stage: TS17
Assay Id: MGI:6382725
Age: embryonic day 10.5
Image: 7
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1309868
Assay Type: RT-PCR
Annotation Date: 1999-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1329901
Age: embryonic day 9.5
Image: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1309868
Assay Type: RT-PCR
Annotation Date: 1999-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1329901
Age: embryonic day 9.5
Image: 2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1309868
Assay Type: RT-PCR
Annotation Date: 1999-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1329901
Age: embryonic day 9.5
Image: 2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1309868
Assay Type: RT-PCR
Annotation Date: 1999-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1329901
Age: embryonic day 9.5
Image: 2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1309868
Assay Type: RT-PCR
Annotation Date: 1999-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1329901
Age: embryonic day 9.5
Image: 2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:1309868
Assay Type: RT-PCR
Annotation Date: 1999-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1329901
Age: embryonic day 9.5
Image: 2
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:1309868
Assay Type: RT-PCR
Annotation Date: 1999-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1329901
Age: embryonic day 9.5
Image: 2
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:1309868
Assay Type: RT-PCR
Annotation Date: 1999-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1329901
Age: embryonic day 9.5
Image: 2
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:4947662
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:4947685
Age: embryonic day 3.0
Image: 2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:1309864
Assay Type: Northern blot
Annotation Date: 1999-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1329898
Age: postnatal adult
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1309864
Assay Type: Northern blot
Annotation Date: 1999-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1329898
Age: postnatal adult
Image: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1309864
Assay Type: Northern blot
Annotation Date: 1999-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1329898
Age: postnatal adult
Image: 2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1309864
Assay Type: Northern blot
Annotation Date: 1999-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1329898
Age: postnatal adult
Image: 2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1309864
Assay Type: Northern blot
Annotation Date: 1999-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1329898
Age: postnatal adult
Image: 2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1309864
Assay Type: Northern blot
Annotation Date: 1999-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1329898
Age: postnatal adult
Image: 2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:4947662
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:4947685
Age: embryonic day 0.5
Image: 2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4947662
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:4947685
Age: embryonic day 3.5
Image: 2
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:4947662
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:4947685
Age: postnatal
Image: 2
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693172
Age: postnatal adult
Image: MRC Harwell_218795
Detected: true
Specimen Num: 19
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693172
Age: postnatal adult
Image: MRC Harwell_218797
Detected: true
Specimen Num: 20
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693172
Age: postnatal adult
Image: MRC Harwell_218801
Note: kidney
Detected: true
Specimen Num: 22
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693172
Age: postnatal adult
Image: MRC Harwell_218781
Detected: true
Specimen Num: 12
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693172
Age: postnatal adult
Image: MRC Harwell_218809
Detected: true
Specimen Num: 26
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1666528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693172
Age: postnatal adult
Image: MRC Harwell_218765
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1619828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693172
Age: postnatal adult
Image: MRC Harwell_218767
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:358407
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824945
Age: embryonic day 14.5
Image: euxassay_002368_04
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:358407
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824945
Age: embryonic day 14.5
Image: euxassay_002368_05
Detected: true
Specimen Num: 2