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Search results 1 to 99 out of 99 for G0s2

0.03s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: This group represents the G0/G1 switch protein 2 (G0S2) []. In humans, it promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers [].
Publication
First Author: Ma T
Year: 2014
Journal: Cancer Biol Ther
Title: Mice lacking G0S2 are lean and cold-tolerant.
Volume: 15
Issue: 5
Pages: 643-50
Publication  
First Author: Corbet AK
Year: 2023
Journal: Transl Oncol
Title: G0S2 promotes antiestrogenic and pro-migratory responses in ER+ and ER- breast cancer cells.
Volume: 33
Pages: 101676
Publication
First Author: Lee PH
Year: 2015
Journal: Immunol Cell Biol
Title: G0S2 modulates homeostatic proliferation of naïve CD8⁺ T cells and inhibits oxidative phosphorylation in mitochondria.
Volume: 93
Issue: 7
Pages: 605-15
Protein
Organism: Mus musculus/domesticus
Length: 103  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 103  
Fragment?: false
Publication
First Author: Russell L
Year: 1991
Journal: DNA Cell Biol
Title: A human putative lymphocyte G0/G1 switch gene containing a CpG-rich island encodes a small basic protein with the potential to be phosphorylated.
Volume: 10
Issue: 8
Pages: 581-91
Publication
First Author: Welch C
Year: 2009
Journal: Cancer Res
Title: Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2.
Volume: 69
Issue: 17
Pages: 6782-9
Publication
First Author: Zhang X
Year: 2014
Journal: Diabetes
Title: Targeted disruption of G0/G1 switch gene 2 enhances adipose lipolysis, alters hepatic energy balance, and alleviates high-fat diet-induced liver steatosis.
Volume: 63
Issue: 3
Pages: 934-46
Publication
First Author: Choi H
Year: 2014
Journal: Cell Death Differ
Title: G0/G1 switch gene 2 has a critical role in adipocyte differentiation.
Volume: 21
Issue: 7
Pages: 1071-80
Publication
First Author: Zhang X
Year: 2019
Journal: FASEB J
Title: Identification of an intrinsic lysophosphatidic acid acyltransferase activity in the lipolytic inhibitor G0/G1 switch gene 2 (G0S2).
Volume: 33
Issue: 5
Pages: 6655-6666
Publication
First Author: El-Assaad W
Year: 2015
Journal: Diabetologia
Title: Deletion of the gene encoding G0/G 1 switch protein 2 (G0s2) alleviates high-fat-diet-induced weight gain and insulin resistance, and promotes browning of white adipose tissue in mice.
Volume: 58
Issue: 1
Pages: 149-57
Publication
First Author: Heckmann BL
Year: 2014
Journal: J Biol Chem
Title: Defective adipose lipolysis and altered global energy metabolism in mice with adipose overexpression of the lipolytic inhibitor G0/G1 switch gene 2 (G0S2).
Volume: 289
Issue: 4
Pages: 1905-16
Publication  
First Author: Zagani R
Year: 2016
Journal: Leuk Res
Title: Deletion of the putative tumor suppressor gene, G0s2, does not affect progression of Eμ-Myc driven lymphomas in mice.
Volume: 40
Pages: 100-2
Publication
First Author: Yang X
Year: 2010
Journal: Cell Metab
Title: The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase.
Volume: 11
Issue: 3
Pages: 194-205
Publication
First Author: Heckmann BL
Year: 2016
Journal: PLoS One
Title: Regulation of G0/G1 Switch Gene 2 (G0S2) Protein Ubiquitination and Stability by Triglyceride Accumulation and ATGL Interaction.
Volume: 11
Issue: 6
Pages: e0156742
Publication
First Author: Zandbergen F
Year: 2005
Journal: Biochem J
Title: The G0/G1 switch gene 2 is a novel PPAR target gene.
Volume: 392
Issue: Pt 2
Pages: 313-24
Publication
First Author: Wueest S
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: Inverse regulation of basal lipolysis in perigonadal and mesenteric fat depots in mice.
Volume: 302
Issue: 1
Pages: E153-60
Publication
First Author: Cornaciu I
Year: 2011
Journal: PLoS One
Title: The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively.
Volume: 6
Issue: 10
Pages: e26349
Publication  
First Author: Ma Y
Year: 2019
Journal: Metabolism
Title: Activation of G0/G1 switch gene 2 by endoplasmic reticulum stress enhances hepatic steatosis.
Volume: 99
Pages: 32-44
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression  
Probe: MGI:1326784
Assay Type: RNA in situ
Annotation Date: 2004-06-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1684624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3042732
Age: embryonic day 16.5
Image: 5d
Specimen Label: 5d
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1326784
Assay Type: RNA in situ
Annotation Date: 2004-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1617724
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3042732
Age: embryonic day 16.5
Image: 5d
Note: Expression was detected in the brown adipose tisue.
Specimen Label: 5d
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1326784
Assay Type: RNA in situ
Annotation Date: 2004-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1617726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3042732
Age: embryonic day 18.5
Image: 6b
Note: Expression was detected in brown adipose tissue.
Specimen Label: 6b
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:1326784
Assay Type: RNA in situ
Annotation Date: 2004-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1617726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3042732
Age: embryonic day 18.5
Image: 6d
Note: Expression was detected in brown and white adipose tissue.
Specimen Label: 6d
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:1326784
Assay Type: RNA in situ
Annotation Date: 2004-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1617726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3042732
Age: embryonic day 18.5
Image: 6f
Note: Expression was detected in white adipose tissue.
Specimen Label: 6f
Detected: true
Specimen Num: 4
Publication
First Author: Bächner D
Year: 1998
Journal: Dev Dyn
Title: Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T1/2).
Volume: 213
Issue: 4
Pages: 398-411
Publication
First Author: Chen Y
Year: 2005
Journal: J Immunol
Title: Several genes contribute to the production of autoreactive B and T cells in the murine lupus susceptibility locus Sle1c.
Volume: 175
Issue: 2
Pages: 1080-9
Publication  
First Author: Babochkina TI
Year: 2022
Journal: Int J Mol Sci
Title: Mother-Fetus Immune Cross-Talk Coordinates "Extrinsic"/"Intrinsic" Embryo Gene Expression Noise and Growth Stability.
Volume: 23
Issue: 20
Publication
First Author: Rana MS
Year: 2014
Journal: Circ Res
Title: Tbx1 coordinates addition of posterior second heart field progenitor cells to the arterial and venous poles of the heart.
Volume: 115
Issue: 9
Pages: 790-9
Publication    
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication  
First Author: Cremer J
Year: 2023
Journal: Cancer Lett
Title: Acidosis-induced regulation of adipocyte G0S2 promotes crosstalk between adipocytes and breast cancer cells as well as tumor progression.
Volume: 569
Pages: 216306
Allele
Name: G0/G1 switch gene 2; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Genotype
Symbol: G0s2/G0s2
Background: involves: C57BL/6NTac
Zygosity: hm
Has Mutant Allele: true
Publication  
First Author: Matsunaga N
Year: 2016
Journal: EBioMedicine
Title: Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease.
Volume: 13
Pages: 262-273
Publication
First Author: Bai X
Year: 2021
Journal: Cell Rep
Title: Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation.
Volume: 36
Issue: 10
Pages: 109659
Publication  
First Author: Zelows MM
Year: 2023
Journal: Mol Metab
Title: Loss of carnitine palmitoyltransferase 1a reduces docosahexaenoic acid-containing phospholipids and drives sexually dimorphic liver disease in mice.
Volume: 78
Pages: 101815
Publication
First Author: Ai K
Year: 2022
Journal: Cell Death Dis
Title: Methyl-CpG-binding domain protein 2 contributes to renal fibrosis through promoting polarized M1 macrophages.
Volume: 13
Issue: 2
Pages: 125
Publication
First Author: Yu Z
Year: 2022
Journal: Blood
Title: Endothelial cell-derived angiopoietin-like protein 2 supports hematopoietic stem cell activities in bone marrow niches.
Volume: 139
Issue: 10
Pages: 1529-1540
Publication
First Author: Wu JW
Year: 2017
Journal: PLoS Genet
Title: Epistatic interaction between the lipase-encoding genes Pnpla2 and Lipe causes liposarcoma in mice.
Volume: 13
Issue: 5
Pages: e1006716
Publication
First Author: Kobayashi S
Year: 2008
Journal: DNA Res
Title: Expression profiling of PBMC-based diagnostic gene markers isolated from vasculitis patients.
Volume: 15
Issue: 4
Pages: 253-65
Publication
First Author: Bednarski T
Year: 2016
Journal: Biochim Biophys Acta
Title: Stearoyl-CoA desaturase 1 deficiency reduces lipid accumulation in the heart by activating lipolysis independently of peroxisome proliferator-activated receptor α.
Volume: 1861
Issue: 12 Pt A
Pages: 2029-2037
Publication
First Author: Fujimoto Y
Year: 2013
Journal: Endocrinology
Title: TFE3 controls lipid metabolism in adipose tissue of male mice by suppressing lipolysis and thermogenesis.
Volume: 154
Issue: 10
Pages: 3577-88
Publication
First Author: Heier C
Year: 2015
Journal: J Biol Chem
Title: G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis.
Volume: 290
Issue: 43
Pages: 26141-50
Publication  
First Author: Hjelholt AJ
Year: 2019
Journal: Mol Metab
Title: Temporal patterns of lipolytic regulators in adipose tissue after acute growth hormone exposure in human subjects: A randomized controlled crossover trial.
Volume: 29
Pages: 65-75