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Search results 1 to 100 out of 127 for G3bp2

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0.044s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Ras GTPase-activating protein-binding protein (also known as GAP SH3 domain-binding protein, G3BP) is involved in several cellular functions and is implicated in stress granule assembly RNA metabolism and hereby cell motility, nuclear transportation and NFkappaB, Ras and Wnt signaling [, ]. There are three human isoforms of G3BP: G3BP1, G3BP2a and G3BP2b. The main difference between the variants is found in the number of PxxP motifs in the central region of the protein []. G3BP contains the PxxP motifs, the glutamine- and glycine rich regions, an RNA recognition motif (RRM) and an N-terminal NTF2-like domain. The NTF2-like domain is the most highly conserved part of the G3BP sequence and it has been implicated in several G3BP functions []. This entry represents G3BP2, which is a cytoplasmic protein that interacts with both IkappaBalpha and IkappaBalpha/NF-kappaB complexes, indicating that G3BP2 may play a role in the control of nucleocytoplasmic distribution of IkappaBalpha and cytoplasmic anchoring of the IkappaBalpha/NF-kappaB complex []. It also contributes to stress granule formation [].
Publication
First Author: Kedersha N
Year: 2016
Journal: J Cell Biol
Title: G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits.
Volume: 212
Issue: 7
Pages: 845-60
Publication
First Author: Matsuki H
Year: 2013
Journal: Genes Cells
Title: Both G3BP1 and G3BP2 contribute to stress granule formation.
Volume: 18
Issue: 2
Pages: 135-46
Publication
First Author: Kristensen O
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Crystal structure of the G3BP2 NTF2-like domain in complex with a canonical FGDF motif peptide.
Volume: 467
Issue: 1
Pages: 53-7
Publication
First Author: Prigent M
Year: 2000
Journal: J Biol Chem
Title: IkappaBalpha and IkappaBalpha /NF-kappa B complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3-binding protein 2.
Volume: 275
Issue: 46
Pages: 36441-9
Protein
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 482  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 550  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 482  
Fragment?: false
Publication
First Author: Vognsen T
Year: 2013
Journal: PLoS One
Title: Crystal structures of the human G3BP1 NTF2-like domain visualize FxFG Nup repeat specificity.
Volume: 8
Issue: 12
Pages: e80947
Publication
First Author: Bikkavilli RK
Year: 2011
Journal: J Cell Sci
Title: Arginine methylation of G3BP1 in response to Wnt3a regulates β-catenin mRNA.
Volume: 124
Issue: Pt 13
Pages: 2310-20
Protein
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 448  
Fragment?: false
Publication
First Author: Bikkavilli RK
Year: 2012
Journal: J Cell Sci
Title: Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2.
Volume: 125
Issue: Pt 10
Pages: 2446-56
Publication  
First Author: Yun D
Year: 2022
Journal: PeerJ
Title: G3BP2, a stress granule assembly factor, is dispensable for spermatogenesis in mice.
Volume: 10
Pages: e13532
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication  
First Author: Kennedy D
Journal: Biomed Pept Proteins Nucleic Acids
Title: Identification of a mouse orthologue of the human ras-GAP-SH3-domain binding protein and structural confirmation that these proteins contain an RNA recognition motif.
Volume: 2
Issue: 3
Pages: 93-9
GXD Expression      
Probe: MGI:3614801
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3616552
Age: embryonic day 13.5
Specimen Label: RT-PCR E13.5 brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3614801
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3616552
Age: postnatal day 0
Specimen Label: RT-PCR P0 brain
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6690829
Assay Type: Western blot
Annotation Date: 2021-04-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1796224
Stage: TS24
Assay Id: MGI:6690876
Age: embryonic day 16.5
Image: 3
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6690829
Assay Type: Western blot
Annotation Date: 2021-04-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1796227
Stage: TS27
Assay Id: MGI:6690876
Age: postnatal day 0
Image: 3
Specimen Label: PD0
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6690829
Assay Type: Western blot
Annotation Date: 2021-04-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1796227
Stage: TS27
Assay Id: MGI:6690876
Age: postnatal day 3
Image: 3
Specimen Label: PD3
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3618129
Age: embryonic day 13.5
Image: E13.5
Note: Expression was detected in precortical tissue.
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1665821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3618129
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3618129
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3618129
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3618129
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3618129
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3618129
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3618129
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618129
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618129
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618129
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618129
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618129
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618129
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3290627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618129
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618129
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618129
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618129
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618129
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618129
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615582
Assay Type: RNA in situ
Annotation Date: 2006-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618129
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6098725
Assay Type: RNA in situ
Annotation Date: 2017-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Pattern: Ubiquitous
Stage: TS11
Assay Id: MGI:6098726
Age: embryonic day 7.5
Specimen Label: E7.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6098725
Assay Type: RNA in situ
Annotation Date: 2017-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Ubiquitous
Stage: TS13
Assay Id: MGI:6098726
Age: embryonic day 8.5
Specimen Label: E8.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6098725
Assay Type: RNA in situ
Annotation Date: 2017-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Ubiquitous
Stage: TS15
Assay Id: MGI:6098726
Age: embryonic day 9.5
Specimen Label: E9.5
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6690829
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1796524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6690859
Age: embryonic day 16.5
Image: 3B E16.5
Specimen Label: 3B E16.5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6690829
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1796527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6690859
Age: postnatal day 0
Image: 3B P0
Note: Mainly expressed at the early-follicle formation stage.
Specimen Label: 3B P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6690829
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1796527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6690859
Age: postnatal day 3
Image: 3B P3
Specimen Label: 3B P3
Detected: true
Specimen Num: 3
Publication
First Author: Wang JJ
Year: 2020
Journal: PLoS Biol
Title: Single-cell transcriptome landscape of ovarian cells during primordial follicle assembly in mice.
Volume: 18
Issue: 12
Pages: e3001025
Publication
First Author: Ryder E
Year: 2013
Journal: Mamm Genome
Title: Molecular characterization of mutant mouse strains generated from the EUCOMM/KOMP-CSD ES cell resource.
Volume: 24
Issue: 7-8
Pages: 286-94
Publication
First Author: Kato Y
Year: 2019
Journal: EMBO Rep
Title: ELAVL2-directed RNA regulatory network drives the formation of quiescent primordial follicles.
Volume: 20
Issue: 12
Pages: e48251
Publication
First Author: Shiina N
Year: 2010
Journal: J Neurosci
Title: RNG105 deficiency impairs the dendritic localization of mRNAs for Na+/K+ ATPase subunit isoforms and leads to the degeneration of neuronal networks.
Volume: 30
Issue: 38
Pages: 12816-30
Publication  
First Author: McKee AE
Year: 2005
Journal: BMC Dev Biol
Title: A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
Volume: 5
Pages: 14
Publication      
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
Publication
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
Publication
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use