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Search results 1 to 58 out of 58 for G6pc

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Type

Details

Score

Gene

key_78990 | G6PC

Type:	gene
Organism:	pig, domestic

•

Gene

100857298 | G6PC

Type:	gene
Organism:	chicken

•

Publication

23856420 | J:205315

First Author:	Lee YM
Year:	2013
Journal:	Mol Genet Metab
Title:	The upstream enhancer elements of the G6PC promoter are critical for optimal G6PC expression in murine glycogen storage disease type Ia.
Volume:	110
Issue:	3
Pages:	275-80

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Publication

29428299 | J:320413

First Author:	Roseman DS
Year:	2018
Journal:	Mol Ther
Title:	G6PC mRNA Therapy Positively Regulates Fasting Blood Glucose and Decreases Liver Abnormalities in a Mouse Model of Glycogen Storage Disease 1a.
Volume:	26
Issue:	3
Pages:	814-821

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Protein

P35576

Organism:	Mus musculus/domesticus
Length:	357
Fragment?:	false

•

Protein Coding Gene

MGI:95607 | G6pc1

Type:	protein_coding_gene
Organism:	mouse, laboratory

•

Allele

G6pc1<em2Smoc> | MGI:7289783

Name:	glucose-6-phosphatase catalytic subunit 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Null/knockout

•

Strain

MGI:6770772 | C57BL/6JSmoc-G6pc<em2Smoc>/Smoc

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

•

Allele

G6pc1<tm1Jyc> | MGI:2387343

Name:	glucose-6-phosphatase catalytic subunit 1; targeted mutation 1, Janice Yang Chou
Allele Type:	Targeted
Attribute String:	Null/knockout

•

Allele

Slc37a4<tm1Jyc> | MGI:3046091

Name:	solute carrier family 37 (glucose-6-phosphate transporter), member 4; targeted mutation 1, Janice Yang Chou
Allele Type:	Targeted
Attribute String:	Null/knockout

•

Allele

G6pc1<tm2.2Jyc> | MGI:4418685

Name:	glucose-6-phosphatase catalytic subunit 1; targeted mutation 2.2, Janice Yang Chou
Allele Type:	Targeted
Attribute String:	Null/knockout

•

Allele

G6pc1<tm1.1Ics> | MGI:5478554

Name:	glucose-6-phosphatase catalytic subunit 1; targeted mutation 1.1, Mouse Clinical Institute
Allele Type:	Targeted
Attribute String:	Conditional ready, No functional change

•

Allele

G6pc1<em1Jyc> | MGI:7506302

Name:	glucose-6-phosphatase catalytic subunit 1; endonuclease-mediated mutation 1, Janice Yang Chou
Allele Type:	Endonuclease-mediated
Attribute String:	Humanized sequence

•

Gene

2538 | G6PC1

Type:	gene
Organism:	human

•

Allele

G6pc1<em1Smoc> | MGI:7289782

Name:	glucose-6-phosphatase catalytic subunit 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Conditional ready, No functional change

•

Protein Coding Gene

MGI:1316650 | Slc37a4

Type:	protein_coding_gene
Organism:	mouse, laboratory

•

Genotype

Symbol:	Slc37a4/Slc37a4
Background:	involves: 129S4/SvJae * C57BL/6
Zygosity:	hm
Has Mutant Allele:	true

•

Genotype

Symbol:	G6pc1/G6pc1
Background:	involves: 129S4/SvJae
Zygosity:	hm
Has Mutant Allele:	true

•

Genotype

Symbol:	G6pc1/G6pc1
Background:	involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6J * FVB/N
Zygosity:	hm
Has Mutant Allele:	true

•

Genotype

Symbol:	G6pc1/G6pc1 Alb/Alb<+>
Background:	involves: 129S2/SvPas * C57BL/6J
Zygosity:	cn
Has Mutant Allele:	true

•

Genotype

Symbol:	G6pc1/G6pc1 Tg(Kap-cre/ERT2)64.9Ics/?
Background:	involves: 129S2/SvPas * FVB/N
Zygosity:	cn
Has Mutant Allele:	true

•

DO Term

DOID:2749 | glycogen storage disease Ia

•

Genotype

Symbol:	G6pc1/G6pc1
Background:	involves: 129S4/SvJae * C57BL/6
Zygosity:	hm
Has Mutant Allele:	true

•

Strain

MGI:6428679 | C57BL/6JSmoc-G6pc<em1Smoc>/Smoc

Attribute String:

coisogenic, mutant strain, endonuclease-mediated mutation

•

Strain

MGI:7781345 | C57BL/6JSmoc-Alb<tm1(cre/ERT2)Smoc> G6pc1<em1Smoc>/Smoc

Attribute String:

coisogenic, mutant strain, targeted mutation

•

Publication

25009184 | J:212254

First Author:	Zhang P
Year:	2014
Journal:	Proc Natl Acad Sci U S A
Title:	Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion.
Volume:	111
Issue:	29
Pages:	10684-9

•

Publication

19548314 | J:155990

First Author:	Peng WT
Year:	2009
Journal:	Genesis
Title:	Generation of mice with a conditional allele for G6pc.
Volume:	47
Issue:	9
Pages:	590-4

•

Publication

34678143 | J:312448

First Author:	Liu Q
Year:	2021
Journal:	Cell
Title:	Glycogen accumulation and phase separation drives liver tumor initiation.
Volume:	184
Issue:	22
Pages:	5559-5576.e19

•

Publication

26615883 | J:274085

First Author:	Lee EY
Year:	2015
Journal:	Sci Rep
Title:	Unsuppressed lipolysis in adipocytes is linked with enhanced gluconeogenesis and altered bile acid physiology in Insr(P1195L/+) mice fed high-fat-diet.
Volume:	5

Pages:	17565

•

Publication

36707678 | J:340199

First Author:	Fang Z
Year:	2023
Journal:	Commun Biol
Title:	Downregulation of hepatic lncRNA Gm19619 improves gluconeogenesis and lipogenesis following vertical sleeve gastrectomy in mice.
Volume:	6
Issue:	1
Pages:	105

•

Publication

20484139 | J:169644

First Author:	Fukushima A
Year:	2010
Journal:	Diabetes
Title:	T-cell protein tyrosine phosphatase attenuates STAT3 and insulin signaling in the liver to regulate gluconeogenesis.
Volume:	59
Issue:	8
Pages:	1906-14

•

Publication

26232096 | J:226423

First Author:	Chung B
Year:	2015
Journal:	Diabetologia
Title:	The diabetes gene Zfp69 modulates hepatic insulin sensitivity in mice.
Volume:	58
Issue:	10
Pages:	2403-13

•

Publication

23995837 | J:204537

First Author:	Singh BK
Year:	2013
Journal:	J Biol Chem
Title:	FoxO1 deacetylation regulates thyroid hormone-induced transcription of key hepatic gluconeogenic genes.
Volume:	288
Issue:	42
Pages:	30365-72

•

Publication

21507897 | J:196866

First Author:	Morán-Salvador E
Year:	2011
Journal:	FASEB J
Title:	Role for PPARγ in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts.
Volume:	25
Issue:	8
Pages:	2538-50

•

Publication

35258009 | J:324928

First Author:	Oh GS
Year:	2022
Journal:	Mol Cells
Title:	Regulation of Hepatic Gluconeogenesis by Nuclear Receptor Coactivator 6.
Volume:	45
Issue:	4
Pages:	180-192

•

Publication

29530977 | J:263803

First Author:	Zhang Y
Year:	2018
Journal:	J Biol Chem
Title:	Regulation of hepatic gluconeogenesis by nuclear factor Y transcription factor in mice.
Volume:	293
Issue:	20
Pages:	7894-7904

•

Publication

21081708 | J:172321

First Author:	Wei D
Year:	2011
Journal:	Am J Physiol Endocrinol Metab
Title:	Feedback regulation of hepatic gluconeogenesis through modulation of SHP/Nr0b2 gene expression by Sirt1 and FoxO1.
Volume:	300
Issue:	2
Pages:	E312-20

•

Publication

16880515 | J:111407

First Author:	Beaudry JB
Year:	2006
Journal:	Mol Cell Biol
Title:	Threshold levels of hepatocyte nuclear factor 6 (HNF-6) acting in synergy with HNF-4 and PGC-1alpha are required for time-specific gene expression during liver development.
Volume:	26
Issue:	16
Pages:	6037-46

•

Publication

26089201 | J:225424

First Author:	Kim GY
Year:	2015
Journal:	Hum Mol Genet
Title:	Mice expressing reduced levels of hepatic glucose-6-phosphatase-α activity do not develop age-related insulin resistance or obesity.
Volume:	24
Issue:	18
Pages:	5115-25

•

Publication

32430177 | J:306074

First Author:	Zhang L
Year:	2020
Journal:	Biochem Biophys Res Commun
Title:	Gene therapy using a novel G6PC-S298C variant enhances the long-term efficacy for treating glycogen storage disease type Ia.
Volume:	527
Issue:	3
Pages:	824-830

•

Publication

33191271 | J:338705

First Author:	Hedman AC
Year:	2021
Journal:	J Biol Chem
Title:	IQGAP1 binds AMPK and is required for maximum AMPK activation.
Volume:	296

Pages:	100075

•

Publication

21109326 | J:195257

First Author:	Mutel E
Year:	2011
Journal:	J Hepatol
Title:	Targeted deletion of liver glucose-6 phosphatase mimics glycogen storage disease type 1a including development of multiple adenomas.
Volume:	54
Issue:	3
Pages:	529-37

•

Publication

27669460 | J:239554

First Author:	Kim MS
Year:	2016
Journal:	J Clin Invest
Title:	ChREBP regulates fructose-induced glucose production independently of insulin signaling.
Volume:	126
Issue:	11
Pages:	4372-4386

•

Publication

28973635 | J:249892

First Author:	Kwon JH
Year:	2017
Journal:	Hum Mol Genet
Title:	Liver-directed gene therapy for murine glycogen storage disease type Ib.
Volume:	26
Issue:	22
Pages:	4395-4405

•

Publication

31813960 | J:285758

First Author:	Saeed A
Year:	2020
Journal:	Hum Mol Genet
Title:	Glycogen storage disease type 1a is associated with disturbed vitamin A metabolism and elevated serum retinol levels.
Volume:	29
Issue:	2
Pages:	264-273

•

Publication

26389569 | J:337197

First Author:	Wang HJ
Year:	2015
Journal:	Autophagy
Title:	Chronic HMGCR/HMG-CoA reductase inhibitor treatment contributes to dysglycemia by upregulating hepatic gluconeogenesis through autophagy induction.
Volume:	11
Issue:	11
Pages:	2089-2101

•

Publication

27436577 | J:237858

First Author:	Gjorgjieva M
Year:	2016
Journal:	Hum Mol Genet
Title:	Progressive development of renal cysts in glycogen storage disease type I.
Volume:	25
Issue:	17
Pages:	3784-3797

•

Publication

28743985 | J:250194

First Author:	Roepke TA
Year:	2017
Journal:	Sci Rep
Title:	Loss of ERα partially reverses the effects of maternal high-fat diet on energy homeostasis in female mice.
Volume:	7
Issue:	1
Pages:	6381

•

Publication

30959128 | J:289781

First Author:	Choi WI
Year:	2019
Journal:	Biochim Biophys Acta Gene Regul Mech
Title:	Zbtb7c is a critical gluconeogenic transcription factor that induces glucose-6-phosphatase and phosphoenylpyruvate carboxykinase 1 genes expression during mice fasting.
Volume:	1862
Issue:	6
Pages:	643-656

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Publication

25561689 | J:220598

First Author:	Clar J
Year:	2015
Journal:	Hum Mol Genet
Title:	Hepatic lentiviral gene transfer prevents the long-term onset of hepatic tumours of glycogen storage disease type 1a in mice.
Volume:	24
Issue:	8
Pages:	2287-96

•

Publication

24717294 | J:238264

First Author:	Clar J
Year:	2014
Journal:	Kidney Int
Title:	Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy.
Volume:	86
Issue:	4
Pages:	747-56

•

Publication

18563384 | J:138021

First Author:	Schilling MM
Year:	2008
Journal:	Diabetologia
Title:	Sequence variation between the mouse and human glucose-6-phosphatase catalytic subunit gene promoters results in differential activation by peroxisome proliferator activated receptor gamma coactivator-1alpha.
Volume:	51
Issue:	8
Pages:	1505-14

•

Publication

26603935 | J:233185

First Author:	Zhu X
Year:	2016
Journal:	Biochem Biophys Res Commun
Title:	Upregulation of lncRNA MEG3 promotes hepatic insulin resistance via increasing FoxO1 expression.
Volume:	469
Issue:	2
Pages:	319-25

•

Publication

31517956 | J:281723

First Author:	Inaba Y
Year:	2019
Journal:	Endocrinology
Title:	Hepatic Gluconeogenic Response to Single and Long-Term SGLT2 Inhibition in Lean/Obese Male Hepatic G6pc-Reporter Mice.
Volume:	160
Issue:	12
Pages:	2811-2824

•

Publication

20103705 | J:164330

First Author:	Charbonneau A
Year:	2010
Journal:	Diabetes
Title:	Inducible nitric oxide synthase induction underlies lipid-induced hepatic insulin resistance in mice: potential role of tyrosine nitration of insulin signaling proteins.
Volume:	59
Issue:	4
Pages:	861-71

•

Publication

33812059 | J:317472

First Author:	Youn DY
Year:	2021
Journal:	Mol Metab
Title:	The Mediator complex kinase module is necessary for fructose regulation of liver glycogen levels through induction of glucose-6-phosphatase catalytic subunit (G6pc).
Volume:	48

Pages:	101227

•

Publication

27656410 | J:277579

First Author:	Arora T
Year:	2016
Journal:	Mol Metab
Title:	Microbially produced glucagon-like peptide 1 improves glucose tolerance in mice.
Volume:	5
Issue:	8
Pages:	725-730

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Publication

- | J:238766

First Author:	Shanghai Model Organisms Center
Year:	2017
Journal:	MGI Direct Data Submission
Title:	Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China

•

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Search results 1 to 58 out of 58 for G6pc

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