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Search results 1 to 100 out of 156 for Gab2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Zhang Y
Year: 2007
Journal: Blood
Title: Abnormal hematopoiesis in Gab2 mutant mice.
Volume: 110
Issue: 1
Pages: 116-24
Publication
First Author: Ke Y
Year: 2007
Journal: Oncogene
Title: Role of Gab2 in mammary tumorigenesis and metastasis.
Volume: 26
Issue: 34
Pages: 4951-60
Publication
First Author: Gu H
Year: 2001
Journal: Nature
Title: Essential role for Gab2 in the allergic response.
Volume: 412
Issue: 6843
Pages: 186-90
Publication
First Author: Nishida K
Year: 2002
Journal: Blood
Title: Requirement of Gab2 for mast cell development and KitL/c-Kit signaling.
Volume: 99
Issue: 5
Pages: 1866-9
Publication
First Author: Yi Q
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Docking protein Gab2 positively regulates glycoprotein VI-mediated platelet activation.
Volume: 337
Issue: 2
Pages: 446-51
Publication
First Author: Zhang X
Year: 2013
Journal: Mol Cell Biol
Title: Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility.
Volume: 33
Issue: 8
Pages: 1657-70
Publication
First Author: Spohr C
Year: 2022
Journal: Leukemia
Title: Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo.
Volume: 36
Issue: 4
Pages: 970-982
Publication
First Author: Yamada K
Year: 2001
Journal: Cytogenet Cell Genet
Title: Comparative FISH mapping of Gab1 and Gab2 genes in human, mouse and rat.
Volume: 94
Issue: 1-2
Pages: 39-42
Publication
First Author: Zhang X
Year: 2012
Journal: FASEB J
Title: Docking protein Gab2 regulates mucin expression and goblet cell hyperplasia through TYK2/STAT6 pathway.
Volume: 26
Issue: 11
Pages: 4603-13
Publication
First Author: Gu S
Year: 2016
Journal: Blood
Title: Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1.
Volume: 127
Issue: 14
Pages: 1803-13
Publication
First Author: Yamasaki S
Year: 2003
Journal: Mol Cell Biol
Title: Gads/Grb2-mediated association with LAT is critical for the inhibitory function of Gab2 in T cells.
Volume: 23
Issue: 7
Pages: 2515-29
Publication
First Author: Gu H
Year: 2003
Journal: J Cell Biol
Title: Critical role for scaffolding adapter Gab2 in Fc gamma R-mediated phagocytosis.
Volume: 161
Issue: 6
Pages: 1151-61
Publication
First Author: Li G
Year: 2010
Journal: PLoS One
Title: Gab2 promotes hematopoietic stem cell maintenance and self-renewal synergistically with STAT5.
Volume: 5
Issue: 2
Pages: e9152
Publication
First Author: Wada T
Year: 2005
Journal: Nat Med
Title: The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis.
Volume: 11
Issue: 4
Pages: 394-9
Publication
First Author: Lee AW
Year: 2011
Journal: Mol Cell Biol
Title: Gab2 promotes colony-stimulating factor 1-regulated macrophage expansion via alternate effectors at different stages of development.
Volume: 31
Issue: 22
Pages: 4563-81
Publication
First Author: Wang X
Year: 2021
Journal: Cell Death Dis
Title: Gab2 deficiency suppresses high-fat diet-induced obesity by reducing adipose tissue inflammation and increasing brown adipose function in mice.
Volume: 12
Issue: 2
Pages: 212
Publication
First Author: Sun J
Year: 2008
Journal: J Biol Chem
Title: Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit.
Volume: 283
Issue: 41
Pages: 27444-51
Publication
First Author: Yu WM
Year: 2002
Journal: Blood
Title: Role of the docking protein Gab2 in beta(1)-integrin signaling pathway-mediated hematopoietic cell adhesion and migration.
Volume: 99
Issue: 7
Pages: 2351-9
Publication
First Author: Kondreddy V
Year: 2021
Journal: Arterioscler Thromb Vasc Biol
Title: Gab2 (Grb2-Associated Binder2) Plays a Crucial Role in Inflammatory Signaling and Endothelial Dysfunction.
Volume: 41
Issue: 6
Pages: 1987-2005
Publication
First Author: Halbach S
Year: 2016
Journal: Leukemia
Title: Gab2 is essential for Bcr-Abl-mediated leukemic transformation and hydronephrosis in a chronic myeloid leukemia mouse model.
Volume: 30
Issue: 9
Pages: 1942-5
Publication
First Author: Chen S
Year: 2016
Journal: J Mol Cell Biol
Title: Deletion of Gab2 in mice protects against hepatic steatosis and steatohepatitis: a novel therapeutic target for fatty liver disease.
Volume: 8
Issue: 6
Pages: 492-504
Publication
First Author: Barbu EA
Year: 2010
Journal: J Biol Chem
Title: The limited contribution of Fyn and Gab2 to the high affinity IgE receptor signaling in mast cells.
Volume: 285
Issue: 21
Pages: 15761-8
Publication
First Author: Guo X
Year: 2017
Journal: J Biol Chem
Title: Increased levels of Gab1 and Gab2 adaptor proteins skew interleukin-4 (IL-4) signaling toward M2 macrophage-driven pulmonary fibrosis in mice.
Volume: 292
Issue: 34
Pages: 14003-14015
Publication  
First Author: Wang Z
Year: 2019
Journal: Front Immunol
Title: Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8+ T-Cell Activation.
Volume: 10
Pages: 486
Publication
First Author: Ni S
Year: 2007
Journal: Mol Cell Biol
Title: A novel Stat3 binding motif in Gab2 mediates transformation of primary hematopoietic cells by the Stk/Ron receptor tyrosine kinase in response to Friend virus infection.
Volume: 27
Issue: 10
Pages: 3708-15
Publication
First Author: Nishida K
Year: 2011
Journal: J Immunol
Title: Gab2, via PI-3K, regulates ARF1 in FcεRI-mediated granule translocation and mast cell degranulation.
Volume: 187
Issue: 2
Pages: 932-41
Publication
First Author: Nishida K
Year: 1999
Journal: Blood
Title: Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors.
Volume: 93
Issue: 6
Pages: 1809-16
Publication
First Author: Zompi S
Year: 2004
Journal: J Leukoc Biol
Title: The absence of Grb2-associated binder 2 (Gab2) does not disrupt NK cell development and functions.
Volume: 76
Issue: 4
Pages: 896-903
Publication
First Author: Li G
Year: 2010
Journal: Leukemia
Title: Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin.
Volume: 24
Issue: 8
Pages: 1397-405
Publication
First Author: Hu S
Year: 2014
Journal: Am J Respir Cell Mol Biol
Title: Growth factor receptor bound protein 2-associated binder 2, a scaffolding adaptor protein, negatively regulates host immunity against tuberculosis.
Volume: 51
Issue: 4
Pages: 575-85
Publication
First Author: Pyarajan S
Year: 2008
Journal: J Biol Chem
Title: Interleukin-3 (IL-3)-induced c-fos activation is modulated by Gab2-calcineurin interaction.
Volume: 283
Issue: 35
Pages: 23505-9
Publication
First Author: Shin YK
Year: 2014
Journal: J Neurosci
Title: Grb2-associated binder-1 is required for neuregulin-1-induced peripheral nerve myelination.
Volume: 34
Issue: 22
Pages: 7657-62
Publication
First Author: Mali RS
Year: 2012
Journal: Blood
Title: Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT.
Volume: 120
Issue: 13
Pages: 2669-78
Publication
First Author: Xu D
Year: 2010
Journal: Blood
Title: A germline gain-of-function mutation in Ptpn11 (Shp-2) phosphatase induces myeloproliferative disease by aberrant activation of hematopoietic stem cells.
Volume: 116
Issue: 18
Pages: 3611-21
Publication
First Author: Teal HE
Year: 2006
Journal: Oncogene
Title: GRB2-mediated recruitment of GAB2, but not GAB1, to SF-STK supports the expansion of Friend virus-infected erythroid progenitor cells.
Volume: 25
Issue: 17
Pages: 2433-43
Publication
First Author: Zhao C
Year: 2003
Journal: J Biol Chem
Title: GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2.
Volume: 278
Issue: 36
Pages: 34641-53
Publication
First Author: Shin YK
Year: 2017
Journal: Glia
Title: Cooperative interaction of hepatocyte growth factor and neuregulin regulates Schwann cell migration and proliferation through Grb2-associated binder-2 in peripheral nerve repair.
Volume: 65
Issue: 11
Pages: 1794-1808
Publication
First Author: Kim HJ
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo.
Volume: 106
Issue: 7
Pages: 2325-30
Publication
First Author: Yu M
Year: 2006
Journal: J Immunol
Title: Scaffolding adapter Grb2-associated binder 2 requires Syk to transmit signals from FcepsilonRI.
Volume: 176
Issue: 4
Pages: 2421-9
Publication
First Author: Mao D
Year: 2006
Journal: J Clin Invest
Title: PLCgamma2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2.
Volume: 116
Issue: 11
Pages: 2869-79
Publication
First Author: Nakaoka Y
Year: 2007
Journal: J Clin Invest
Title: Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling.
Volume: 117
Issue: 7
Pages: 1771-81
Publication
First Author: Yu M
Year: 2006
Journal: J Biol Chem
Title: The scaffolding adapter Gab2, via Shp-2, regulates kit-evoked mast cell proliferation by activating the Rac/JNK pathway.
Volume: 281
Issue: 39
Pages: 28615-26
Publication
First Author: Kettner A
Year: 2010
Journal: Mol Immunol
Title: Insulin potentiates FcepsilonRI-mediated signaling in mouse bone marrow-derived mast cells.
Volume: 47
Issue: 5
Pages: 1039-46
Publication
First Author: Shioyama W
Year: 2011
Journal: Circ Res
Title: Docking protein Gab1 is an essential component of postnatal angiogenesis after ischemia via HGF/c-met signaling.
Volume: 108
Issue: 6
Pages: 664-75
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Gu H
Year: 1998
Journal: Mol Cell
Title: Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation.
Volume: 2
Issue: 6
Pages: 729-40
GXD Expression  
Probe: MGI:3759268
Assay Type: RNA in situ
Annotation Date: 2007-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3516422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3759270
Age: embryonic day 13.75
Image: 3C
Specimen Label: 3C
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3759268
Assay Type: RNA in situ
Annotation Date: 2007-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3759270
Age: embryonic day 13.75
Image: 3C
Specimen Label: 3C
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3759268
Assay Type: RNA in situ
Annotation Date: 2007-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3759270
Age: embryonic day 13.75
Image: 3C
Note: Expression is in the basal diencephalon.
Specimen Label: 3C
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4423460
Assay Type: RNA in situ
Annotation Date: 2019-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3806722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6381364
Age: embryonic day 14.5
Image: 1C32
Specimen Label: 1C32
Detected: true
Specimen Num: 1
Publication
First Author: Li H
Year: 2014
Journal: J Cell Sci
Title: Frs2α and Shp2 signal independently of Gab to mediate FGF signaling in lens development.
Volume: 127
Issue: Pt 3
Pages: 571-82
Publication
First Author: Hegde S
Year: 2009
Journal: Oncogene
Title: Stat3 promotes the development of erythroleukemia by inducing Pu.1 expression and inhibiting erythroid differentiation.
Volume: 28
Issue: 38
Pages: 3349-59
Publication
First Author: Jochner MCE
Year: 2019
Journal: Sci Rep
Title: Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress.
Volume: 9
Issue: 1
Pages: 3183
Publication
First Author: Wang Z
Year: 2009
Journal: Blood
Title: Conditional deletion of STAT5 in adult mouse hematopoietic stem cells causes loss of quiescence and permits efficient nonablative stem cell replacement.
Volume: 113
Issue: 20
Pages: 4856-65
Publication
First Author: Liu W
Year: 2017
Journal: Leukemia
Title: Inhibition of the Gab2/PI3K/mTOR signaling ameliorates myeloid malignancy caused by Ptpn11 (Shp2) gain-of-function mutations.
Volume: 31
Issue: 6
Pages: 1415-1422
Publication
First Author: Nishida K
Year: 2005
Journal: J Cell Biol
Title: Fc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane.
Volume: 170
Issue: 1
Pages: 115-26
Publication
First Author: Kohno M
Year: 2005
Journal: Blood
Title: Rapid and large amount of autocrine IL-3 production is responsible for mast cell survival by IgE in the absence of antigen.
Volume: 105
Issue: 5
Pages: 2059-65
Publication    
First Author: Zhou L
Year: 2020
Journal: Elife
Title: Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination.
Volume: 9
Publication
First Author: Choi HK
Year: 2013
Journal: Cell Res
Title: Early estrogen-induced gene 1, a novel RANK signaling component, is essential for osteoclastogenesis.
Volume: 23
Issue: 4
Pages: 524-36
Publication
First Author: Titz B
Year: 2010
Journal: Oncogene
Title: The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization.
Volume: 29
Issue: 44
Pages: 5895-910
Publication
First Author: Higuchi T
Year: 2004
Journal: Mol Cell Biol
Title: MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.
Volume: 24
Issue: 17
Pages: 7456-68
Publication      
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
Publication  
First Author: Koutelou E
Year: 2019
Journal: Development
Title: USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta.
Volume: 146
Issue: 4
Publication
First Author: Gurdziel K
Year: 2016
Journal: Dev Dyn
Title: Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.
Volume: 245
Issue: 5
Pages: 614-26
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42