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Search results 1 to 100 out of 799 for Gas1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
2619 | GAS1
Type: gene
Organism: human
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Gene
780149 | gas1
Type: gene
Organism: frog, western clawed
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Gene
607496 | GAS1
Type: gene
Organism: dog, domestic
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Gene
736324 | GAS1
Type: gene
Organism: chimpanzee
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Gene
683470 | Gas1
Type: gene
Organism: rat
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Gene
540336 | GAS1
Type: gene
Organism: cattle
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Gene
770168 | GAS1
Type: gene
Organism: chicken
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Gene
694650 | GAS1
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR039596 | GAS1
Type: Family
Description: Growth arrest-specific protein 1 (GAS1) is a glycosylphosphatidylinositol-anchored protein involved in growth suppression [, , ]. It inhibits cell proliferation when overexpressed in normal and transformed cell lines, and reduces tumour cell growth []. It also promotes apoptosis [], plays a role in mouse embryonic development [], and suppresses melanoma metastases [].
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Protein Coding Gene
MGI:95655 | Gas1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10996315 | J:64788
First Author: Stebel M
Year: 2000
Journal: FEBS Lett
Title: The growth suppressing gas1 product is a GPI-linked protein.
Volume: 481
Issue: 2
Pages: 152-8
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Publication
18981472 | J:140931
First Author: Gobeil S
Year: 2008
Journal: Genes Dev
Title: A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene.
Volume: 22
Issue: 21
Pages: 2932-40
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Protein
Q7TNT6
Organism: Mus musculus/domesticus
Length: 280  
Fragment?: true
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GXD Expression
GXD Expression
 
Probe: MGI:3724328
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2622022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826214
Age: embryonic day 14.5
Image: Additional file 4 Gas1
Specimen Label: Additional file 4 Gas1
Detected: true
Specimen Num: 1
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Gene
100506834 | GAS1RR
Type: gene
Organism: human
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Publication
1505026 | J:41311
First Author: Del Sal G
Year: 1992
Journal: Cell
Title: The growth arrest-specific gene, gas1, is involved in growth suppression.
Volume: 70
Issue: 4
Pages: 595-607
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Publication
26161998 | J:238379
First Author: Sacilotto N
Year: 2015
Journal: PLoS One
Title: Growth Arrest Specific 1 (Gas1) Gene Overexpression in Liver Reduces the In Vivo Progression of Murine Hepatocellular Carcinoma and Partially Restores Gene Expression Levels.
Volume: 10
Issue: 7
Pages: e0132477
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Publication
11356029 | J:69636
First Author: Lee KK
Year: 2001
Journal: Dev Biol
Title: Functions of the growth arrest specific 1 gene in the development of the mouse embryo.
Volume: 234
Issue: 1
Pages: 188-203
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Publication
12503088 | -
First Author: Zamorano A
Year: 2003
Journal: J Neurosci Res
Title: Transcriptionally mediated gene targeting of gas1 to glioma cells elicits growth arrest and apoptosis.
Volume: 71
Issue: 2
Pages: 256-63
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Publication
10996316 | J:180495
First Author: Ruaro ME
Year: 2000
Journal: FEBS Lett
Title: Analysis of the domain requirement in Gas1 growth suppressing activity.
Volume: 481
Issue: 2
Pages: 159-63
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Publication
11231094 | J:68155
First Author: Lee CS
Year: 2001
Journal: Mech Dev
Title: Embryonic expression patterns of the mouse and chick Gas1 genes.
Volume: 101
Issue: 1-2
Pages: 293-7
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Publication
11955608 | J:113995
First Author: Agostoni E
Year: 2002
Journal: Biochim Biophys Acta
Title: Cloning and characterization of the C. elegans gas1 homolog: phas-1.
Volume: 1574
Issue: 1
Pages: 1-9
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Publication
11906213 | J:75866
First Author: Mellström B
Year: 2002
Journal: Mol Cell Neurosci
Title: Gas1 is induced during and participates in excitotoxic neuronal death.
Volume: 19
Issue: 3
Pages: 417-29
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Protein
Q01721
Organism: Mus musculus/domesticus
Length: 343  
Fragment?: false
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Protein
A0A286YD87
Organism: Mus musculus/domesticus
Length: 384  
Fragment?: false
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Publication
17504940 | J:121554
First Author: Martinelli DC
Year: 2007
Journal: Genes Dev
Title: Gas1 extends the range of Hedgehog action by facilitating its signaling.
Volume: 21
Issue: 10
Pages: 1231-43
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Publication
15070677 | J:180480
First Author: Spagnuolo R
Year: 2004
Journal: Blood
Title: Gas1 is induced by VE-cadherin and vascular endothelial growth factor and inhibits endothelial cell apoptosis.
Volume: 103
Issue: 8
Pages: 3005-12
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Publication
25063195 | J:216223
First Author: Seppala M
Year: 2014
Journal: Biol Open
Title: Boc modifies the spectrum of holoprosencephaly in the absence of Gas1 function.
Volume: 3
Issue: 8
Pages: 728-40
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Publication
32021964 | J:314871
First Author: Li L
Year: 2019
Journal: Nat Metab
Title: Muscle stem cell renewal suppressed by Gas1 can be reversed by GDNF in mice.
Volume: 1
Issue: 10
Pages: 985-995
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Publication
25804736 | J:220461
First Author: Kann M
Year: 2015
Journal: Development
Title: WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals.
Volume: 142
Issue: 7
Pages: 1254-66
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Publication
23429478 | J:192870
First Author: Biau S
Year: 2013
Journal: Biol Open
Title: Gastrointestinal defects of the Gas1 mutant involve dysregulated Hedgehog and Ret signaling.
Volume: 2
Issue: 2
Pages: 144-55
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Publication
21858068 | -
First Author: Sacilotto N
Year: 2011
Journal: PLoS One
Title: Epigenetic transcriptional regulation of the growth arrest-specific gene 1 (Gas1) in hepatic cell proliferation at mononucleosomal resolution.
Volume: 6
Issue: 8
Pages: e23318
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Publication
8127893 | J:17106
First Author: Del Sal G
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Structure, function, and chromosome mapping of the growth-suppressing human homologue of the murine gas1 gene.
Volume: 91
Issue: 5
Pages: 1848-52
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Publication
17504941 | J:121553
First Author: Allen BL
Year: 2007
Journal: Genes Dev
Title: The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development.
Volume: 21
Issue: 10
Pages: 1244-57
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Publication
17525797 | J:122159
First Author: Seppala M
Year: 2007
Journal: J Clin Invest
Title: Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog.
Volume: 117
Issue: 6
Pages: 1575-84
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Publication
34698766 | J:314133
 
First Author: Marczenke M
Year: 2021
Journal: Development
Title: GAS1 is required for NOTCH-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium.
Volume: 148
Issue: 21
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Publication
27811357 | J:310333
First Author: Xavier GM
Year: 2016
Journal: Oncotarget
Title: Genetic interactions between the hedgehog co-receptors Gas1 and Boc regulate cell proliferation during murine palatogenesis.
Volume: 7
Issue: 48
Pages: 79233-79246
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Publication
34796774 | J:335331
First Author: Seppala M
Year: 2022
Journal: J Dent Res
Title: Gas1 Regulates Patterning of the Murine and Human Dentitions through Sonic Hedgehog.
Volume: 101
Issue: 4
Pages: 473-482
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Publication
21664577 | J:173603
First Author: Izzi L
Year: 2011
Journal: Dev Cell
Title: Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation.
Volume: 20
Issue: 6
Pages: 788-801
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GXD Expression
GXD Expression
   
Probe: MGI:6173360
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190372
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Gas1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6173360
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190372
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Gas1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6173360
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190372
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Gas1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6173360
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190372
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Gas1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6173360
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190372
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Gas1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6173360
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190372
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Gas1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6173360
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190372
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Gas1
Detected: true
Specimen Num: 7
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Publication
25535338 | J:218163
First Author: Jin S
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Gas1 is a receptor for sonic hedgehog to repel enteric axons.
Volume: 112
Issue: 1
Pages: E73-80
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Publication
33028094 | J:318636
First Author: Chapouly C
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Desert Hedgehog-Driven Endothelium Integrity Is Enhanced by Gas1 (Growth Arrest-Specific 1) but Negatively Regulated by Cdon (Cell Adhesion Molecule-Related/Downregulated by Oncogenes).
Volume: 40
Issue: 12
Pages: e336-e349
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Publication
11456442 | J:70736
First Author: Liu Y
Year: 2001
Journal: Dev Biol
Title: Growth arrest specific gene 1 is a positive growth regulator for the cerebellum.
Volume: 236
Issue: 1
Pages: 30-45
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Publication
11572986 | J:71832
First Author: Lee CS
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite.
Volume: 98
Issue: 20
Pages: 11347-52
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Publication
19478089 | J:152270
First Author: Martinelli DC
Year: 2009
Journal: J Biol Chem
Title: A sonic hedgehog missense mutation associated with holoprosencephaly causes defective binding to GAS1.
Volume: 284
Issue: 29
Pages: 19169-72
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Publication
32332736 | J:291852
First Author: Kim Y
Year: 2020
Journal: Nat Commun
Title: Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration.
Volume: 11
Issue: 1
Pages: 1994
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Publication
26740594 | J:232348
First Author: Ren YA
Year: 2016
Journal: Biol Reprod
Title: Growth Arrest Specific-1 (GAS1) Is a C/EBP Target Gene That Functions in Ovulation and Corpus Luteum Formation in Mice.
Volume: 94
Issue: 2
Pages: 44
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Publication
16168717 | J:104154
First Author: Rice R
Year: 2006
Journal: Gene Expr Patterns
Title: Expression patterns of Hedgehog signalling pathway members during mouse palate development.
Volume: 6
Issue: 2
Pages: 206-12
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Publication
22898775 | J:187715
First Author: Xie L
Year: 2012
Journal: Dev Cell
Title: Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation.
Volume: 23
Issue: 2
Pages: 280-91
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Publication
39629522 | J:361259
 
First Author: Franks NE
Year: 2024
Journal: Development
Title: Hedgehog-dependent and hedgehog-independent roles for growth arrest specific 1 in mammalian kidney morphogenesis.
Volume: 151
Issue: 24
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Publication
29395133 | J:260965
First Author: Quezada-Ramírez MA
Year: 2018
Journal: Exp Cell Res
Title: The Growth arrest specific 1 (Gas1) gene is transcriptionally regulated by NeuroD1 via two distal E-boxes.
Volume: 363
Issue: 2
Pages: 332-341
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HT Experiment
E-MTAB-10207 | GAS1 is required for Notch-dependent facilitation of SHH signalling in forebrain development
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
15151988 | J:91052
First Author: Cobourne MT
Year: 2004
Journal: Development
Title: Restriction of sonic hedgehog signalling during early tooth development.
Volume: 131
Issue: 12
Pages: 2875-85
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Publication
28799057 | J:257526
First Author: Feuerstein M
Year: 2017
Journal: Cell Tissue Res
Title: Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line.
Volume: 370
Issue: 2
Pages: 211-225
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Publication
33060130 | J:300506
 
First Author: Echevarría-Andino ML
Year: 2020
Journal: Development
Title: The hedgehog co-receptor BOC differentially regulates SHH signaling during craniofacial development.
Volume: 147
Issue: 23
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Publication
19211681 | J:146634
First Author: Ohazama A
Year: 2009
Journal: Development
Title: Primary cilia regulate Shh activity in the control of molar tooth number.
Volume: 136
Issue: 6
Pages: 897-903
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Publication
36459481 | J:332136
   
First Author: Li X
Year: 2022
Journal: Elife
Title: Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis.
Volume: 11
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Publication
36971701 | J:335153
 
First Author: Qiu T
Year: 2023
Journal: Development
Title: Molecular profiling of the vestibular lamina highlights a key role for Hedgehog signalling.
Volume: 150
Issue: 7
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Publication
12399319 | J:79482
First Author: Liu Y
Year: 2002
Journal: Development
Title: Growth arrest specific gene 1 acts as a region-specific mediator of the Fgf10/Fgf8 regulatory loop in the limb.
Volume: 129
Issue: 22
Pages: 5289-300
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Publication
37516749 | J:338829
First Author: Lee J
Year: 2023
Journal: Sci Rep
Title: Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development.
Volume: 13
Issue: 1
Pages: 12309
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Publication
38848388 | J:351872
First Author: Kumari A
Year: 2024
Journal: PLoS One
Title: Distinct expression patterns of Hedgehog signaling components in mouse gustatory system during postnatal tongue development and adult homeostasis.
Volume: 19
Issue: 6
Pages: e0294835
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Publication
11456441 | J:70735
First Author: Lee CS
Year: 2001
Journal: Dev Biol
Title: Transdifferentiation of the ventral retinal pigmented epithelium to neural retina in the growth arrest specific gene 1 mutant.
Volume: 236
Issue: 1
Pages: 17-29
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Protein Coding Gene
MGP_CAROLIEiJ_G0018613 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020646 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020601 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020577 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020597 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020394 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_95655 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021031 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019910 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020354 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020478 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020456 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020554 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020486 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021074 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019665 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019972 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0019677 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019492 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1427878 | J:2678
First Author: Webb GC
Year: 1992
Journal: Genomics
Title: Assignment, by in situ hybridization, of the growth arrest-specific gene, Gas-1, to mouse chromosome 13, bands B3-C2.
Volume: 14
Issue: 2
Pages: 548-9
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Publication
8226788 | J:15275
First Author: de Martin R
Year: 1993
Journal: J Biol Chem
Title: Structure and regulation of the growth arrest-specific (gas-1) promoter.
Volume: 268
Issue: 30
Pages: 22788-93
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Publication
8307588 | J:16137
First Author: Evdokiou A
Year: 1993
Journal: Genomics
Title: Localization of the human growth arrest-specific gene (GAS1) to chromosome bands 9q21.3-q22, a region frequently deleted in myeloid malignancies.
Volume: 18
Issue: 3
Pages: 731-3
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Publication
9188486 | J:41211
First Author: Autry JM
Year: 1997
Journal: J Biol Chem
Title: Functional Co-expression of the canine cardiac Ca2+ pump and phospholamban in Spodoptera frugiperda (Sf21) cells reveals new insights on ATPase regulation.
Volume: 272
Issue: 25
Pages: 15872-80
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GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 9
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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