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Search results 1 to 100 out of 792 for Gas1

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
2619 | GAS1
Type: gene
Organism: human
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Gene
683470 | Gas1
Type: gene
Organism: rat
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Gene
540336 | GAS1
Type: gene
Organism: cattle
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Gene
770168 | GAS1
Type: gene
Organism: chicken
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Gene
694650 | GAS1
Type: gene
Organism: macaque, rhesus
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Gene
780149 | gas1
Type: gene
Organism: frog, western clawed
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Gene
607496 | GAS1
Type: gene
Organism: dog, domestic
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Gene
736324 | GAS1
Type: gene
Organism: chimpanzee
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Protein Domain
IPR039596 | GAS1
Type: Family
Description: Growth arrest-specific protein 1 (GAS1) is a glycosylphosphatidylinositol-anchored protein involved in growth suppression [, , ]. It inhibits cell proliferation when overexpressed in normal and transformed cell lines, and reduces tumour cell growth []. It also promotes apoptosis [], plays a role in mouse embryonic development [], and suppresses melanoma metastases [].
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Protein Coding Gene
MGI:95655 | Gas1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10996315 | J:64788
First Author: Stebel M
Year: 2000
Journal: FEBS Lett
Title: The growth suppressing gas1 product is a GPI-linked protein.
Volume: 481
Issue: 2
Pages: 152-8
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Publication
18981472 | J:140931
First Author: Gobeil S
Year: 2008
Journal: Genes Dev
Title: A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene.
Volume: 22
Issue: 21
Pages: 2932-40
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Protein
Q7TNT6
Organism: Mus musculus/domesticus
Length: 280  
Fragment?: true
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GXD Expression
GXD Expression
 
Probe: MGI:3724328
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2622022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826214
Age: embryonic day 14.5
Image: Additional file 4 Gas1
Specimen Label: Additional file 4 Gas1
Detected: true
Specimen Num: 1
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Gene
100506834 | GAS1RR
Type: gene
Organism: human
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Publication
1505026 | J:41311
First Author: Del Sal G
Year: 1992
Journal: Cell
Title: The growth arrest-specific gene, gas1, is involved in growth suppression.
Volume: 70
Issue: 4
Pages: 595-607
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Publication
26161998 | J:238379
First Author: Sacilotto N
Year: 2015
Journal: PLoS One
Title: Growth Arrest Specific 1 (Gas1) Gene Overexpression in Liver Reduces the In Vivo Progression of Murine Hepatocellular Carcinoma and Partially Restores Gene Expression Levels.
Volume: 10
Issue: 7
Pages: e0132477
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Publication
11356029 | J:69636
First Author: Lee KK
Year: 2001
Journal: Dev Biol
Title: Functions of the growth arrest specific 1 gene in the development of the mouse embryo.
Volume: 234
Issue: 1
Pages: 188-203
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Publication
12503088 | -
First Author: Zamorano A
Year: 2003
Journal: J Neurosci Res
Title: Transcriptionally mediated gene targeting of gas1 to glioma cells elicits growth arrest and apoptosis.
Volume: 71
Issue: 2
Pages: 256-63
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Publication
10996316 | J:180495
First Author: Ruaro ME
Year: 2000
Journal: FEBS Lett
Title: Analysis of the domain requirement in Gas1 growth suppressing activity.
Volume: 481
Issue: 2
Pages: 159-63
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Publication
11955608 | J:113995
First Author: Agostoni E
Year: 2002
Journal: Biochim Biophys Acta
Title: Cloning and characterization of the C. elegans gas1 homolog: phas-1.
Volume: 1574
Issue: 1
Pages: 1-9
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Publication
11231094 | J:68155
First Author: Lee CS
Year: 2001
Journal: Mech Dev
Title: Embryonic expression patterns of the mouse and chick Gas1 genes.
Volume: 101
Issue: 1-2
Pages: 293-7
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Publication
11906213 | J:75866
First Author: Mellström B
Year: 2002
Journal: Mol Cell Neurosci
Title: Gas1 is induced during and participates in excitotoxic neuronal death.
Volume: 19
Issue: 3
Pages: 417-29
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Protein
Q01721
Organism: Mus musculus/domesticus
Length: 343  
Fragment?: false
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Protein
A0A286YD87
Organism: Mus musculus/domesticus
Length: 384  
Fragment?: false
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Publication
17504940 | J:121554
First Author: Martinelli DC
Year: 2007
Journal: Genes Dev
Title: Gas1 extends the range of Hedgehog action by facilitating its signaling.
Volume: 21
Issue: 10
Pages: 1231-43
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Publication
15070677 | J:180480
First Author: Spagnuolo R
Year: 2004
Journal: Blood
Title: Gas1 is induced by VE-cadherin and vascular endothelial growth factor and inhibits endothelial cell apoptosis.
Volume: 103
Issue: 8
Pages: 3005-12
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Publication
25063195 | J:216223
First Author: Seppala M
Year: 2014
Journal: Biol Open
Title: Boc modifies the spectrum of holoprosencephaly in the absence of Gas1 function.
Volume: 3
Issue: 8
Pages: 728-40
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Publication
32021964 | J:314871
First Author: Li L
Year: 2019
Journal: Nat Metab
Title: Muscle stem cell renewal suppressed by Gas1 can be reversed by GDNF in mice.
Volume: 1
Issue: 10
Pages: 985-995
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Publication
25804736 | J:220461
First Author: Kann M
Year: 2015
Journal: Development
Title: WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals.
Volume: 142
Issue: 7
Pages: 1254-66
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Publication
23429478 | J:192870
First Author: Biau S
Year: 2013
Journal: Biol Open
Title: Gastrointestinal defects of the Gas1 mutant involve dysregulated Hedgehog and Ret signaling.
Volume: 2
Issue: 2
Pages: 144-55
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Publication
21858068 | -
First Author: Sacilotto N
Year: 2011
Journal: PLoS One
Title: Epigenetic transcriptional regulation of the growth arrest-specific gene 1 (Gas1) in hepatic cell proliferation at mononucleosomal resolution.
Volume: 6
Issue: 8
Pages: e23318
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Publication
8127893 | J:17106
First Author: Del Sal G
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Structure, function, and chromosome mapping of the growth-suppressing human homologue of the murine gas1 gene.
Volume: 91
Issue: 5
Pages: 1848-52
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Publication
17504941 | J:121553
First Author: Allen BL
Year: 2007
Journal: Genes Dev
Title: The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development.
Volume: 21
Issue: 10
Pages: 1244-57
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Publication
17525797 | J:122159
First Author: Seppala M
Year: 2007
Journal: J Clin Invest
Title: Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog.
Volume: 117
Issue: 6
Pages: 1575-84
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Publication
34698766 | J:314133
 
First Author: Marczenke M
Year: 2021
Journal: Development
Title: GAS1 is required for NOTCH-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium.
Volume: 148
Issue: 21
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Publication
27811357 | J:310333
First Author: Xavier GM
Year: 2016
Journal: Oncotarget
Title: Genetic interactions between the hedgehog co-receptors Gas1 and Boc regulate cell proliferation during murine palatogenesis.
Volume: 7
Issue: 48
Pages: 79233-79246
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Publication
34796774 | J:335331
First Author: Seppala M
Year: 2022
Journal: J Dent Res
Title: Gas1 Regulates Patterning of the Murine and Human Dentitions through Sonic Hedgehog.
Volume: 101
Issue: 4
Pages: 473-482
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Publication
21664577 | J:173603
First Author: Izzi L
Year: 2011
Journal: Dev Cell
Title: Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation.
Volume: 20
Issue: 6
Pages: 788-801
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GXD Expression
GXD Expression
   
Probe: MGI:6173360
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190372
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Gas1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6173360
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190372
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Gas1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6173360
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190372
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Gas1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6173360
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190372
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Gas1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6173360
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190372
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Gas1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6173360
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190372
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Gas1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6173360
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190372
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Gas1
Detected: true
Specimen Num: 7
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Publication
25535338 | J:218163
First Author: Jin S
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Gas1 is a receptor for sonic hedgehog to repel enteric axons.
Volume: 112
Issue: 1
Pages: E73-80
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Publication
33028094 | J:318636
First Author: Chapouly C
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Desert Hedgehog-Driven Endothelium Integrity Is Enhanced by Gas1 (Growth Arrest-Specific 1) but Negatively Regulated by Cdon (Cell Adhesion Molecule-Related/Downregulated by Oncogenes).
Volume: 40
Issue: 12
Pages: e336-e349
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Publication
11456442 | J:70736
First Author: Liu Y
Year: 2001
Journal: Dev Biol
Title: Growth arrest specific gene 1 is a positive growth regulator for the cerebellum.
Volume: 236
Issue: 1
Pages: 30-45
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Publication
11572986 | J:71832
First Author: Lee CS
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite.
Volume: 98
Issue: 20
Pages: 11347-52
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Publication
19478089 | J:152270
First Author: Martinelli DC
Year: 2009
Journal: J Biol Chem
Title: A sonic hedgehog missense mutation associated with holoprosencephaly causes defective binding to GAS1.
Volume: 284
Issue: 29
Pages: 19169-72
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Publication
32332736 | J:291852
First Author: Kim Y
Year: 2020
Journal: Nat Commun
Title: Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration.
Volume: 11
Issue: 1
Pages: 1994
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Publication
26740594 | J:232348
First Author: Ren YA
Year: 2016
Journal: Biol Reprod
Title: Growth Arrest Specific-1 (GAS1) Is a C/EBP Target Gene That Functions in Ovulation and Corpus Luteum Formation in Mice.
Volume: 94
Issue: 2
Pages: 44
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Publication
16168717 | J:104154
First Author: Rice R
Year: 2006
Journal: Gene Expr Patterns
Title: Expression patterns of Hedgehog signalling pathway members during mouse palate development.
Volume: 6
Issue: 2
Pages: 206-12
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Publication
22898775 | J:187715
First Author: Xie L
Year: 2012
Journal: Dev Cell
Title: Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation.
Volume: 23
Issue: 2
Pages: 280-91
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Publication
29395133 | J:260965
First Author: Quezada-Ramírez MA
Year: 2018
Journal: Exp Cell Res
Title: The Growth arrest specific 1 (Gas1) gene is transcriptionally regulated by NeuroD1 via two distal E-boxes.
Volume: 363
Issue: 2
Pages: 332-341
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HT Experiment
E-MTAB-10207 | GAS1 is required for Notch-dependent facilitation of SHH signalling in forebrain development
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
15151988 | J:91052
First Author: Cobourne MT
Year: 2004
Journal: Development
Title: Restriction of sonic hedgehog signalling during early tooth development.
Volume: 131
Issue: 12
Pages: 2875-85
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Publication
28799057 | J:257526
First Author: Feuerstein M
Year: 2017
Journal: Cell Tissue Res
Title: Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line.
Volume: 370
Issue: 2
Pages: 211-225
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Publication
33060130 | J:300506
 
First Author: Echevarría-Andino ML
Year: 2020
Journal: Development
Title: The hedgehog co-receptor BOC differentially regulates SHH signaling during craniofacial development.
Volume: 147
Issue: 23
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Publication
19211681 | J:146634
First Author: Ohazama A
Year: 2009
Journal: Development
Title: Primary cilia regulate Shh activity in the control of molar tooth number.
Volume: 136
Issue: 6
Pages: 897-903
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Publication
36459481 | J:332136
   
First Author: Li X
Year: 2022
Journal: Elife
Title: Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis.
Volume: 11
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Publication
12399319 | J:79482
First Author: Liu Y
Year: 2002
Journal: Development
Title: Growth arrest specific gene 1 acts as a region-specific mediator of the Fgf10/Fgf8 regulatory loop in the limb.
Volume: 129
Issue: 22
Pages: 5289-300
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Publication
36971701 | J:335153
 
First Author: Qiu T
Year: 2023
Journal: Development
Title: Molecular profiling of the vestibular lamina highlights a key role for Hedgehog signalling.
Volume: 150
Issue: 7
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Publication
37516749 | J:338829
First Author: Lee J
Year: 2023
Journal: Sci Rep
Title: Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development.
Volume: 13
Issue: 1
Pages: 12309
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Publication
11456441 | J:70735
First Author: Lee CS
Year: 2001
Journal: Dev Biol
Title: Transdifferentiation of the ventral retinal pigmented epithelium to neural retina in the growth arrest specific gene 1 mutant.
Volume: 236
Issue: 1
Pages: 17-29
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Protein Coding Gene
MGP_CAROLIEiJ_G0018613 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020646 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020601 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020577 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020597 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020394 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_95655 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021031 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019910 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020354 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020478 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020456 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020554 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020486 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021074 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019665 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019972 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0019677 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019492 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1427878 | J:2678
First Author: Webb GC
Year: 1992
Journal: Genomics
Title: Assignment, by in situ hybridization, of the growth arrest-specific gene, Gas-1, to mouse chromosome 13, bands B3-C2.
Volume: 14
Issue: 2
Pages: 548-9
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Publication
8226788 | J:15275
First Author: de Martin R
Year: 1993
Journal: J Biol Chem
Title: Structure and regulation of the growth arrest-specific (gas-1) promoter.
Volume: 268
Issue: 30
Pages: 22788-93
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Publication
8307588 | J:16137
First Author: Evdokiou A
Year: 1993
Journal: Genomics
Title: Localization of the human growth arrest-specific gene (GAS1) to chromosome bands 9q21.3-q22, a region frequently deleted in myeloid malignancies.
Volume: 18
Issue: 3
Pages: 731-3
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Publication
9188486 | J:41211
First Author: Autry JM
Year: 1997
Journal: J Biol Chem
Title: Functional Co-expression of the canine cardiac Ca2+ pump and phospholamban in Spodoptera frugiperda (Sf21) cells reveals new insights on ATPase regulation.
Volume: 272
Issue: 25
Pages: 15872-80
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GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1204497
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1204499
Age: postnatal week 6-8
Image: st96_185
Specimen Label: None
Detected: true
Specimen Num: 11
•
•
•
•
•




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