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Search results 1 to 100 out of 225 for Gast

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0.068s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Gastrin is a hormonal regulator of various digestive processes and feeding behaviours. It induces gastric secretion, stimulates pancreatic secretion, increases blood circulation and water secretion in the stomach and intestine, and stimulates smooth muscle contraction. Originally found in the gut, it has since been shown to be present in various parts of the nervous system. Like many other active peptides gastrin is synthesized as a larger protein precursor that is enzymatically converted to its mature form. It is found in several molecular forms due to tissue-specific post-translational processing. The biological activity of gastrin is associated with the last five C-terminal residues. One or two positions downstream, there is a conserved sulphated tyrosine residue [, ]. Cionin, a neuropeptide from the protochordate Ciona intestinalis, belongs to this family.
GXD Expression  
Probe: MGI:3248217
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3565022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825901
Age: embryonic day 14.5
Image: Additional file 4 Gast
Specimen Label: Additional file 4 Gast
Detected: true
Specimen Num: 1
Publication
First Author: Gast M
Year: 2019
Journal: Cardiovasc Res
Title: Immune system-mediated atherosclerosis caused by deficiency of long non-coding RNA MALAT1 in ApoE-/-mice.
Volume: 115
Issue: 2
Pages: 302-314
GXD Expression    
Probe: MGI:6458510
Assay Type: Western blot
Annotation Date: 2020-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3537528
Stage: TS28
Assay Id: MGI:6458562
Age: postnatal adult
Image: 1
Specimen Label: GAST
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6727868
Assay Type: Western blot
Annotation Date: 2021-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3537528
Stage: TS28
Assay Id: MGI:6727920
Age: postnatal
Image: 3
Specimen Label: GAST
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6727868
Assay Type: Western blot
Annotation Date: 2021-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3537528
Stage: TS28
Assay Id: MGI:6727920
Age: postnatal
Image: 3
Specimen Label: GAST
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:6727868
Assay Type: Western blot
Annotation Date: 2021-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3537528
Stage: TS28
Assay Id: MGI:6727920
Age: postnatal
Image: 3
Specimen Label: GAST
Detected: true
Specimen Num: 9
Publication
First Author: Gast M
Year: 2019
Journal: Cardiovasc Res
Title: Long noncoding RNA NEAT1 modulates immune cell functions and is suppressed in early onset myocardial infarction patients.
Volume: 115
Issue: 13
Pages: 1886-1906
Protein
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 79  
Fragment?: true
Publication
First Author: Baldwin GS
Year: 2010
Journal: Curr Opin Endocrinol Diabetes Obes
Title: Evolution of gastrointestinal hormones: the cholecystokinin/gastrin family.
Volume: 17
Issue: 1
Pages: 77-88
Publication
First Author: Shulkes A
Year: 1997
Journal: Clin Exp Pharmacol Physiol
Title: Biology of gut cholecystokinin and gastrin receptors.
Volume: 24
Issue: 3-4
Pages: 209-16
Publication
First Author: Umar S
Year: 2009
Journal: J Biol Chem
Title: Functional cross-talk between beta-catenin and NFkappaB signaling pathways in colonic crypts of mice in response to progastrin.
Volume: 284
Issue: 33
Pages: 22274-84
Publication
First Author: Takaishi S
Year: 2011
Journal: Am J Physiol Gastrointest Liver Physiol
Title: In vivo analysis of mouse gastrin gene regulation in enhanced GFP-BAC transgenic mice.
Volume: 300
Issue: 2
Pages: G334-44
Publication
First Author: Jiang X
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: Gastrin stimulates renal dopamine production by increasing the renal tubular uptake of l-DOPA.
Volume: 312
Issue: 1
Pages: E1-E10
Publication
First Author: Pannequin J
Year: 2007
Journal: Gastroenterology
Title: Beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors.
Volume: 133
Issue: 5
Pages: 1554-68
Publication
First Author: Liu P
Year: 1998
Journal: Genetics
Title: Embryonic lethality and tumorigenesis caused by segmental aneuploidy on mouse chromosome 11.
Volume: 150
Issue: 3
Pages: 1155-68
Publication
First Author: Saqui-Salces M
Year: 2012
Journal: PLoS One
Title: Inflammation and Gli2 suppress gastrin gene expression in a murine model of antral hyperplasia.
Volume: 7
Issue: 10
Pages: e48039
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Koh TJ
Year: 1995
Journal: Biochem Biophys Res Commun
Title: Molecular cloning and sequencing of the murine gastrin gene.
Volume: 216
Issue: 1
Pages: 34-41
Publication
First Author: Noh MJ
Year: 1995
Journal: Biochem Mol Biol Int
Title: Sequences responsible for transcription termination of the mouse gastrin gene.
Volume: 35
Issue: 6
Pages: 1205-13
Publication
First Author: Wang TC
Year: 1993
Journal: J Clin Invest
Title: Pancreatic gastrin stimulates islet differentiation of transforming growth factor alpha-induced ductular precursor cells.
Volume: 92
Issue: 3
Pages: 1349-56
Publication
First Author: Wang TC
Year: 2000
Journal: Gastroenterology
Title: Synergistic interaction between hypergastrinemia and Helicobacter infection in a mouse model of gastric cancer.
Volume: 118
Issue: 1
Pages: 36-47
Publication
First Author: Ottewell PD
Year: 2006
Journal: Gastroenterology
Title: Gastrin increases murine intestinal crypt regeneration following injury.
Volume: 130
Issue: 4
Pages: 1169-80
Publication
First Author: Takaishi S
Year: 2009
Journal: Am J Pathol
Title: Gastrin is an essential cofactor for helicobacter-associated gastric corpus carcinogenesis in C57BL/6 mice.
Volume: 175
Issue: 1
Pages: 365-75
Publication
First Author: Kirton CM
Year: 2002
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Regulation of parietal cell migration by gastrin in the mouse.
Volume: 283
Issue: 3
Pages: G787-93
Publication
First Author: Koh TJ
Year: 1997
Journal: Gastroenterology
Title: Gastrin deficiency results in altered gastric differentiation and decreased colonic proliferation in mice.
Volume: 113
Issue: 3
Pages: 1015-25
Publication
First Author: Ottewell PD
Year: 2005
Journal: Am J Physiol Gastrointest Liver Physiol
Title: COOH-terminal 26-amino acid residues of progastrin are sufficient for stimulation of mitosis in murine colonic epithelium in vivo.
Volume: 288
Issue: 3
Pages: G541-9
Publication
First Author: Chen D
Year: 2000
Journal: Gastroenterology
Title: Glycine-extended gastrin synergizes with gastrin 17 to stimulate acid secretion in gastrin-deficient mice.
Volume: 119
Issue: 3
Pages: 756-65
Publication
First Author: Boushey RP
Year: 2003
Journal: Gastroenterology
Title: Hypoglycemia, defective islet glucagon secretion, but normal islet mass in mice with a disruption of the gastrin gene.
Volume: 125
Issue: 4
Pages: 1164-74
Publication
First Author: Nomura S
Year: 2005
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Alterations in gastric mucosal lineages induced by acute oxyntic atrophy in wild-type and gastrin-deficient mice.
Volume: 288
Issue: 2
Pages: G362-75
Publication
First Author: Friis-Hansen L
Year: 1998
Journal: Am J Physiol
Title: Impaired gastric acid secretion in gastrin-deficient mice.
Volume: 274
Issue: 3 Pt 1
Pages: G561-8
Publication
First Author: Kang W
Year: 2005
Journal: Lab Invest
Title: Interferon gamma induction of gastric mucous neck cell hypertrophy.
Volume: 85
Issue: 5
Pages: 702-15
Publication
First Author: Zavros Y
Year: 2002
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hypergastrinemia in response to gastric inflammation suppresses somatostatin.
Volume: 282
Issue: 1
Pages: G175-83
Publication
First Author: van den Buuse M
Year: 2005
Journal: Neurosci Lett
Title: Reduced effects of amphetamine on prepulse inhibition of startle in gastrin-deficient mice.
Volume: 373
Issue: 3
Pages: 237-42
Publication
First Author: Franic TV
Year: 2004
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Growth factors associated with gastric mucosal hypertrophy in autoimmune gastritis.
Volume: 287
Issue: 4
Pages: G910-8
Publication
First Author: Zhao CM
Year: 2003
Journal: Regul Pept
Title: Chronic Helicobacter pylori infection results in gastric hypoacidity and hypergastrinemia in wild-type mice but vagally induced hypersecretion in gastrin-deficient mice.
Volume: 115
Issue: 3
Pages: 161-70
Publication
First Author: Friis-Hansen L
Year: 2006
Journal: Gastroenterology
Title: Gastric inflammation, metaplasia, and tumor development in gastrin-deficient mice.
Volume: 131
Issue: 1
Pages: 246-58
Publication
First Author: Hinkle KL
Year: 2003
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Enhanced calcium signaling and acid secretion in parietal cells isolated from gastrin-deficient mice.
Volume: 284
Issue: 1
Pages: G145-53
Publication
First Author: Lu YC
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Transgenic insulin released from G cells preferentially signals in the liver.
Volume: 355
Issue: 1
Pages: 23-7
Publication
First Author: Cobb S
Year: 2002
Journal: Gastroenterology
Title: Deletion of functional gastrin gene markedly increases colon carcinogenesis in response to azoxymethane in mice.
Volume: 123
Issue: 2
Pages: 516-30
Publication
First Author: Cowey SL
Year: 2005
Journal: Cancer
Title: Abdominal obesity, insulin resistance, and colon carcinogenesis are increased in mutant mice lacking gastrin gene expression.
Volume: 103
Issue: 12
Pages: 2643-53
Publication
First Author: Laval M
Year: 2015
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Increased gastrin gene expression provides a physiological advantage to mice under hypoxic conditions.
Volume: 308
Issue: 2
Pages: G76-84
Publication
First Author: Koh TJ
Year: 1999
Journal: J Clin Invest
Title: Overexpression of glycine-extended gastrin in transgenic mice results in increased colonic proliferation.
Volume: 103
Issue: 8
Pages: 1119-26
Publication
First Author: Wang TC
Year: 1999
Journal: Am J Physiol
Title: Lessons from genetically engineered animal models. I. Physiological studies with gastrin in transgenic mice.
Volume: 277
Issue: 1 Pt 1
Pages: G6-11
Publication  
First Author: Nakajima T
Year: 2002
Journal: Aliment Pharmacol Ther
Title: Gastrin interferes with the differentiation of gastric pit cells and parietal cells.
Volume: 16 Suppl 2
Pages: 3-9
GXD Expression    
Probe: MGI:3826382
Assay Type: RT-PCR
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706619
Stage: TS19
Assay Id: MGI:3826457
Age: embryonic day 11.5
Image: 4
Specimen Label: TS19
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3826382
Assay Type: RT-PCR
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750321
Stage: TS21
Assay Id: MGI:3826457
Age: embryonic day 13.5
Image: 4
Specimen Label: TS21
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3826382
Assay Type: RT-PCR
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750323
Stage: TS23
Assay Id: MGI:3826457
Age: embryonic day 15.5
Image: 4
Specimen Label: TS23
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3826382
Assay Type: RT-PCR
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:3826457
Age: embryonic day 18.5
Image: 4
Specimen Label: TS26
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3826382
Assay Type: RT-PCR
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3295228
Stage: TS28
Assay Id: MGI:3826457
Age: postnatal adult
Image: 4
Specimen Label: Ducts
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3826382
Assay Type: RT-PCR
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Stage: TS28
Assay Id: MGI:3826457
Age: postnatal adult
Image: 4
Specimen Label: Islets
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4357882
Assay Type: RT-PCR
Annotation Date: 2009-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702125
Stage: TS25
Assay Id: MGI:4358219
Age: embryonic day 17.5
Specimen Label: St
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4357882
Assay Type: RT-PCR
Annotation Date: 2009-09-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287425
Stage: TS25
Assay Id: MGI:4358219
Age: embryonic day 17.5
Specimen Label: Int
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:7448631
Assay Type: RT-PCR
Annotation Date: 2023-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702125
Stage: TS25
Assay Id: MGI:7448840
Age: embryonic day 17.5
Image: 3
Specimen Label: control stomach
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7448631
Assay Type: RT-PCR
Annotation Date: 2023-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287425
Stage: TS25
Assay Id: MGI:7448840
Age: embryonic day 17.5
Image: 3
Specimen Label: control intestine
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7448631
Assay Type: RT-PCR
Annotation Date: 2023-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287425
Stage: TS25
Assay Id: MGI:7448840
Age: embryonic day 17.5
Image: 3
Specimen Label: Int intestine
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5429356
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1789128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384669
Age: postnatal day 8
Note: Expression was detected in G cells.
Specimen Label: S7d Wt
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5429356
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1789128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384669
Age: postnatal day 8
Note: The number of Gastrin-expressing cells was reduced in the absence of Percc1.
Specimen Label: S7d delta ICR/delta ICR
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7462457
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2718128
Stage: TS28
Assay Id: MGI:7464004
Age: postnatal adult
Image: S8D - corpus
Specimen Label: S8D - corpus
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3616032
Assay Type: Immunohistochemistry
Annotation Date: 2006-03-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3616033
Age: postnatal adult
Image: S4B
Specimen Label: S4B
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3616032
Assay Type: Immunohistochemistry
Annotation Date: 2006-03-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3616033
Age: postnatal adult
Image: S4F
Note: The authors state that expression in this mutant is the same as in wild-type embryos.
Specimen Label: S4F
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3248217
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825001
Age: embryonic day 14.5
Image: euxassay_006638_08
Specimen Label: euxassay_006638_08
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3248217
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825001
Age: embryonic day 14.5
Image: euxassay_006638_09
Specimen Label: euxassay_006638_09
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3248217
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825001
Age: embryonic day 14.5
Image: euxassay_006638_10
Specimen Label: euxassay_006638_10
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3248217
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825001
Age: embryonic day 14.5
Image: euxassay_006638_11
Specimen Label: euxassay_006638_11
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3248217
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825001
Age: embryonic day 14.5
Image: euxassay_006638_12
Specimen Label: euxassay_006638_12
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3248217
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825001
Age: embryonic day 14.5
Image: euxassay_006638_13
Specimen Label: euxassay_006638_13
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:3248217
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825001
Age: embryonic day 14.5
Image: euxassay_006638_16
Specimen Label: euxassay_006638_16
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3248217
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825001
Age: embryonic day 14.5
Image: euxassay_006638_17
Specimen Label: euxassay_006638_17
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:7462457
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2721128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7464004
Age: postnatal adult
Image: S8D - antrum
Specimen Label: S8D - antrum
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5429356
Assay Type: Immunohistochemistry
Annotation Date: 2012-08-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5429965
Age: postnatal adult
Image: 2N
Note: Gastrin+/Isl1+ cells were found. However, the majority of gastrin+ cells are Isl1 negative.
Specimen Label: 2N
Detected: true
Specimen Num: 1
Publication
First Author: Nozaki K
Year: 2009
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Altered gastric chief cell lineage differentiation in histamine-deficient mice.
Volume: 296
Issue: 6
Pages: G1211-20