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Search results 1 to 100 out of 1653 for Gata2

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
2624 | GATA2
Type: gene
Organism: human
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Gene
484626 | GATA2
Type: gene
Organism: dog, domestic
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Gene
506809 | GATA2
Type: gene
Organism: cattle
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Gene
416018 | GATA2
Type: gene
Organism: chicken
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Gene
705551 | GATA2
Type: gene
Organism: macaque, rhesus
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Gene
100487142 | gata2
Type: gene
Organism: frog, western clawed
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Gene
25159 | Gata2
Type: gene
Organism: rat
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Gene
460672 | GATA2
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:95662 | Gata2
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
101927167 | GATA2-AS1
Type: gene
Organism: human
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GXD Expression
GXD Expression
 
Probe: MGI:3506454
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Strong
Sex: Female
Emaps: EMAPS:3152723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6513166
Age: embryonic day 15.5
Image: 5 - Gata2
Specimen Label: 5 - Gata2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3724457
Assay Type: RNA in situ
Annotation Date: 2021-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3152722
Pattern: Widespread
Stage: TS22
Assay Id: MGI:6514163
Age: embryonic day 14.5
Image: 8D - Gata2
Specimen Label: 8D - Gata2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3506454
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Strong
Sex: Female
Emaps: EMAPS:3607823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6513166
Age: embryonic day 15.5
Image: 6 - Gata2
Note: Expression is seen in a banded pattern throughout the bladder neck and upper urethra.
Specimen Label: 6 - Gata2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3506454
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Strong
Sex: Female
Emaps: EMAPS:2875323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6513166
Age: embryonic day 15.5
Image: 6 - Gata2
Note: Expression is seen in a banded pattern throughout the bladder neck and upper urethra.
Specimen Label: 6 - Gata2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3506454
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Strong
Sex: Female
Emaps: EMAPS:3152723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6513166
Age: embryonic day 15.5
Image: 6 - Gata2
Specimen Label: 6 - Gata2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3724457
Assay Type: RNA in situ
Annotation Date: 2021-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3607822
Pattern: Widespread
Stage: TS22
Assay Id: MGI:6514163
Age: embryonic day 14.5
Image: 8D - Gata2
Specimen Label: 8D - Gata2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3506454
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Strong
Sex: Female
Emaps: EMAPS:2876523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6513166
Age: embryonic day 15.5
Image: 5 - Gata2
Note: Expression is seen in the upper third of the urethra.
Specimen Label: 5 - Gata2
Detected: true
Specimen Num: 1
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Publication
27259979 | J:236269
First Author: Onodera K
Year: 2016
Journal: Blood
Title: GATA2 regulates dendritic cell differentiation.
Volume: 128
Issue: 4
Pages: 508-18
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Publication
28630119 | J:244389
First Author: Katayama S
Year: 2017
Journal: Blood
Title: GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis.
Volume: 130
Issue: 7
Pages: 908-919
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Publication
32594099 | J:303661
First Author: You X
Year: 2021
Journal: Leukemia
Title: Gata2 -77 enhancer regulates adult hematopoietic stem cell survival.
Volume: 35
Issue: 3
Pages: 901-905
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Publication
30620726 | J:295045
First Author: Soukup AA
Year: 2019
Journal: J Clin Invest
Title: Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer.
Volume: 129
Issue: 3
Pages: 1180-1192
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Publication
32562431 | J:297686
First Author: Watanabe-Asaka T
Year: 2020
Journal: Genes Cells
Title: GATA2 functions in adrenal chromaffin cells.
Volume: 25
Issue: 9
Pages: 607-614
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Publication
24297994 | J:327395
First Author: Gao X
Year: 2013
Journal: J Exp Med
Title: Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo.
Volume: 210
Issue: 13
Pages: 2833-42
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GXD Expression
GXD Expression
 
Probe: MGI:3724457
Assay Type: RNA in situ
Annotation Date: 2011-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4936866
Age: embryonic day 14.5
Note: Expression is present in single cells in which the intercellular distance between stained cells is much larger than the cell diameter of an individual cell. A thumbnail photo of the staining is contained in the table.
Specimen Label: Table S9 - Gata2
Detected: true
Specimen Num: 1
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Publication
34125173 | J:314999
First Author: Katerndahl CDS
Year: 2021
Journal: Blood
Title: Tumor suppressor function of Gata2 in acute promyelocytic leukemia.
Volume: 138
Issue: 13
Pages: 1148-1161
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Publication
30710465 | J:284553
First Author: Harada N
Year: 2019
Journal: Cancer Sci
Title: GATA2 hypomorphism induces chronic myelomonocytic leukemia in mice.
Volume: 110
Issue: 4
Pages: 1183-1193
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Publication
37580379 | J:339095
First Author: Silvério-Alves R
Year: 2023
Journal: Nat Commun
Title: GATA2 mitotic bookmarking is required for definitive haematopoiesis.
Volume: 14
Issue: 1
Pages: 4645
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Publication
9021157 | J:37789
First Author: Ciciotte SL
Year: 1997
Journal: Mamm Genome
Title: Gata2 maps to mouse chromosome 6.
Volume: 8
Issue: 1
Pages: 69-70
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Publication
16082385 | J:100710
First Author: Tsai J
Year: 2005
Journal: EMBO Rep
Title: The transcription factor GATA2 regulates differentiation of brown adipocytes.
Volume: 6
Issue: 9
Pages: 879-84
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Publication
17166922 | J:122546
First Author: Lugus JJ
Year: 2007
Journal: Development
Title: GATA2 functions at multiple steps in hemangioblast development and differentiation.
Volume: 134
Issue: 2
Pages: 393-405
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Publication
17395646 | J:121242
First Author: Khandekar M
Year: 2007
Journal: Development
Title: A Gata2 intronic enhancer confers its pan-endothelia-specific regulation.
Volume: 134
Issue: 9
Pages: 1703-12
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Publication
14973276 | J:88591
First Author: Craven SE
Year: 2004
Journal: Development
Title: Gata2 specifies serotonergic neurons downstream of sonic hedgehog.
Volume: 131
Issue: 5
Pages: 1165-73
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Publication
10934027 | J:63686
First Author: Zhou Y
Year: 2000
Journal: Development
Title: GATA2 is required for the generation of V2 interneurons.
Volume: 127
Issue: 17
Pages: 3829-38
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Publication
22996665 | J:191750
First Author: Lim KC
Year: 2012
Journal: J Clin Invest
Title: Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning.
Volume: 122
Issue: 10
Pages: 3705-17
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Publication
16543408 | J:108963
First Author: Charles MA
Year: 2006
Journal: Mol Endocrinol
Title: Pituitary-specific Gata2 knockout: effects on gonadotrope and thyrotrope function.
Volume: 20
Issue: 6
Pages: 1366-77
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Publication
25848090 | J:224396
First Author: Malik J
Year: 2015
Journal: Mol Cell Biol
Title: Histone methyltransferase Setd8 represses Gata2 expression and regulates erythroid maturation.
Volume: 35
Issue: 12
Pages: 2059-72
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Publication
24297996 | J:225707
First Author: de Pater E
Year: 2013
Journal: J Exp Med
Title: Gata2 is required for HSC generation and survival.
Volume: 210
Issue: 13
Pages: 2843-50
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Publication
26214525 | J:225799
First Author: Kazenwadel J
Year: 2015
Journal: J Clin Invest
Title: GATA2 is required for lymphatic vessel valve development and maintenance.
Volume: 125
Issue: 8
Pages: 2979-94
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Publication
15542836 | J:95123
First Author: Khandekar M
Year: 2004
Journal: Mol Cell Biol
Title: Multiple, distant Gata2 enhancers specify temporally and tissue-specific patterning in the developing urogenital system.
Volume: 24
Issue: 23
Pages: 10263-76
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Publication
32649900 | J:313626
First Author: Ahmed N
Year: 2020
Journal: Stem Cell Reports
Title: A Novel GATA2 Protein Reporter Mouse Reveals Hematopoietic Progenitor Cell Types.
Volume: 15
Issue: 2
Pages: 326-339
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Publication
26812161 | J:233899
First Author: Li X
Year: 2016
Journal: Endocrinology
Title: Gata2 Is a Rheostat for Mesenchymal Stem Cell Fate in Male Mice.
Volume: 157
Issue: 3
Pages: 1021-8
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Publication
28866324 | J:313228
 
First Author: Hasegawa S
Year: 2017
Journal: Exp Hematol
Title: Effects of in vivo deletion of GATA2 in bone marrow stromal cells.
Volume: 56
Pages: 31-45.e2
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Publication
22541434 | J:186195
First Author: Kumar MS
Year: 2012
Journal: Cell
Title: The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer.
Volume: 149
Issue: 3
Pages: 642-55
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Publication
16055713 | J:218152
First Author: Kobayashi-Osaki M
Year: 2005
Journal: Mol Cell Biol
Title: GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene.
Volume: 25
Issue: 16
Pages: 7005-20
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Publication
33193444 | J:313494
 
First Author: Yin C
Year: 2020
Journal: Front Immunol
Title: Efferocytic Defects in Early Atherosclerosis Are Driven by GATA2 Overexpression in Macrophages.
Volume: 11
Pages: 594136
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Publication
23911012 | J:215433
First Author: Suzuki M
Year: 2013
Journal: Genes Cells
Title: GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation.
Volume: 18
Issue: 11
Pages: 921-33
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Publication
19371385 | J:158265
First Author: Nozawa D
Year: 2009
Journal: Genes Cells
Title: GATA2-dependent and region-specific regulation of Gata2 transcription in the mouse midbrain.
Volume: 14
Issue: 5
Pages: 569-82
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Publication
33479210 | J:301256
First Author: Li Y
Year: 2021
Journal: Nat Commun
Title: GATA2 regulates mast cell identity and responsiveness to antigenic stimulation by promoting chromatin remodeling at super-enhancers.
Volume: 12
Issue: 1
Pages: 494
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Publication
31582413 | J:284120
 
First Author: Mahamud MR
Year: 2019
Journal: Development
Title: GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126.
Volume: 146
Issue: 21
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Publication
19088086 | J:143527
First Author: Kala K
Year: 2009
Journal: Development
Title: Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neurons.
Volume: 136
Issue: 2
Pages: 253-62
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Publication
31378673 | J:290781
First Author: Menendez-Gonzalez JB
Year: 2019
Journal: Stem Cell Reports
Title: Gata2 as a Crucial Regulator of Stem Cells in Adult Hematopoiesis and Acute Myeloid Leukemia.
Volume: 13
Issue: 2
Pages: 291-306
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Publication
16672344 | J:109529
First Author: El Wakil A
Year: 2006
Journal: Development
Title: The GATA2 transcription factor negatively regulates the proliferation of neuronal progenitors.
Volume: 133
Issue: 11
Pages: 2155-65
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Publication
15499560 | J:93820
First Author: Lilleväli K
Year: 2004
Journal: Dev Dyn
Title: Partially overlapping expression of Gata2 and Gata3 during inner ear development.
Volume: 231
Issue: 4
Pages: 775-81
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Publication
28807932 | J:248934
 
First Author: Yu L
Year: 2017
Journal: Mol Cell Biol
Title: Reducing Inflammatory Cytokine Production from Renal Collecting Duct Cells by Inhibiting GATA2 Ameliorates Acute Kidney Injury.
Volume: 37
Issue: 22
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Publication
35440757 | J:325406
First Author: Hasegawa A
Year: 2022
Journal: Commun Biol
Title: Heterozygous variants in GATA2 contribute to DCML deficiency in mice by disrupting tandem protein binding.
Volume: 5
Issue: 1
Pages: 376
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Publication
25907033 | J:230335
First Author: Nandakumar SK
Year: 2015
Journal: Exp Hematol
Title: Low-level GATA2 overexpression promotes myeloid progenitor self-renewal and blocks lymphoid differentiation in mice.
Volume: 43
Issue: 7
Pages: 565-77.e1-10
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Publication
28569748 | J:249574
 
First Author: Qiu C
Year: 2017
Journal: Nat Commun
Title: The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis.
Volume: 8
Pages: 15426
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Publication
16461905 | J:106045
First Author: Suzuki N
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Combinatorial Gata2 and Sca1 expression defines hematopoietic stem cells in the bone marrow niche.
Volume: 103
Issue: 7
Pages: 2202-7
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Publication
29217535 | J:257598
First Author: Eich C
Year: 2018
Journal: J Exp Med
Title: In vivo single cell analysis reveals Gata2 dynamics in cells transitioning to hematopoietic fate.
Volume: 215
Issue: 1
Pages: 233-248
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Publication
24636993 | J:215365
First Author: Yu L
Year: 2014
Journal: Mol Cell Biol
Title: GATA2 regulates body water homeostasis through maintaining aquaporin 2 expression in renal collecting ducts.
Volume: 34
Issue: 11
Pages: 1929-41
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Publication
22476030 | J:341511
First Author: Rubel CA
Year: 2012
Journal: Gene Expr Patterns
Title: GATA2 is expressed at critical times in the mouse uterus during pregnancy.
Volume: 12
Issue: 5-6
Pages: 196-203
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Publication
24583263 | J:209350
First Author: Shi X
Year: 2014
Journal: Dev Biol
Title: Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages.
Volume: 389
Issue: 2
Pages: 208-18
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Publication
20652952 | J:163272
First Author: Haugas M
Year: 2010
Journal: Dev Dyn
Title: Gata2 is required for the development of inner ear semicircular ducts and the surrounding perilymphatic space.
Volume: 239
Issue: 9
Pages: 2452-69
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Publication
29581184 | J:265280
     
First Author: Tolkachov A
Year: 2018
Journal: Mol Cell Biol
Title: Loss of the hematopoietic stem cell factor GATA2 in the osteogenic lineage impairs trabecularization and mechanical strength of bone.
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Publication
19136559 | J:148819
First Author: Schupp M
Year: 2009
Journal: J Biol Chem
Title: Re-expression of GATA2 cooperates with peroxisome proliferator-activated receptor-gamma depletion to revert the adipocyte phenotype.
Volume: 284
Issue: 14
Pages: 9458-64
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Publication
10367888 | J:70561
First Author: Dasen JS
Year: 1999
Journal: Cell
Title: Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types.
Volume: 97
Issue: 5
Pages: 587-98
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Publication
23840778 | J:204328
First Author: Tondeleir D
Year: 2013
Journal: PLoS One
Title: Beta-Actin Is Involved in Modulating Erythropoiesis during Development by Fine-Tuning Gata2 Expression Levels.
Volume: 8
Issue: 6
Pages: e67855
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Publication
31624376 | J:285744
First Author: Saida S
Year: 2020
Journal: Leukemia
Title: Gata2 deficiency delays leukemogenesis while contributing to aggressive leukemia phenotype in Cbfb-MYH11 knockin mice.
Volume: 34
Issue: 3
Pages: 759-770
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Publication
19528235 | J:151520
First Author: Yang Z
Year: 2009
Journal: Mol Cell Biol
Title: Increased c-Jun expression and reduced GATA2 expression promote aberrant monocytic differentiation induced by activating PTPN11 mutants.
Volume: 29
Issue: 16
Pages: 4376-93
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GXD Expression
GXD Expression
   
Probe: MGI:6173374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190373
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Gata2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6173374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190373
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Gata2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6173374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190373
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Gata2
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6173374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190373
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Gata2
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6173374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190373
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Gata2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6173374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190373
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Gata2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6173374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190373
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Gata2
Detected: true
Specimen Num: 7
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Publication
25870111 | J:316445
First Author: Marks-Bluth J
Year: 2015
Journal: Mol Cell Biol
Title: SMAD1 and SMAD5 Expression Is Coordinately Regulated by FLI1 and GATA2 during Endothelial Development.
Volume: 35
Issue: 12
Pages: 2165-72
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Publication
18211891 | J:135228
First Author: Brandt W
Year: 2008
Journal: J Biol Chem
Title: Defining the functional boundaries of the Gata2 locus by rescue with a linked bacterial artificial chromosome transgene.
Volume: 283
Issue: 14
Pages: 8976-83
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Publication
25369423 | J:237449
First Author: Francius C
Year: 2015
Journal: Dev Neurobiol
Title: Genetic dissection of Gata2 selective functions during specification of V2 interneurons in the developing spinal cord.
Volume: 75
Issue: 7
Pages: 721-37
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Publication
18233958 | J:138257
First Author: Hoshino T
Year: 2008
Journal: Genes Cells
Title: Reduced BMP4 abundance in Gata2 hypomorphic mutant mice result in uropathies resembling human CAKUT.
Volume: 13
Issue: 2
Pages: 159-70
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Publication
15689374 | J:97176
First Author: Robert-Moreno A
Year: 2005
Journal: Development
Title: RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.
Volume: 132
Issue: 5
Pages: 1117-26
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Publication
27789623 | J:237535
First Author: Haugas M
Year: 2016
Journal: Development
Title: Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe.
Volume: 143
Issue: 23
Pages: 4495-4508
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Publication
25855601 | J:222625
First Author: Ohmori S
Year: 2015
Journal: Blood
Title: GATA2 is critical for the maintenance of cellular identity in differentiated mast cells derived from mouse bone marrow.
Volume: 125
Issue: 21
Pages: 3306-15
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•
•
•
•
Publication
37386251 | J:342641
First Author: Tenney AP
Year: 2023
Journal: Nat Genet
Title: Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis.
Volume: 55
Issue: 7
Pages: 1149-1163
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Publication
31501274 | J:291300
 
First Author: Ohmori S
Year: 2019
Journal: Mol Cell Biol
Title: GATA2 and PU.1 Collaborate To Activate the Expression of the Mouse Ms4a2 Gene, Encoding FcεRIβ, through Distinct Mechanisms.
Volume: 39
Issue: 22
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Publication
22493062 | J:185715
First Author: Ainoya K
Year: 2012
Journal: Mol Cell Biol
Title: UG4 enhancer-driven GATA-2 and bone morphogenetic protein 4 complementation remedies the CAKUT phenotype in Gata2 hypomorphic mutant mice.
Volume: 32
Issue: 12
Pages: 2312-22
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Publication
15837948 | J:109684
First Author: Menghini R
Year: 2005
Journal: Circulation
Title: Phosphorylation of GATA2 by Akt increases adipose tissue differentiation and reduces adipose tissue-related inflammation: a novel pathway linking obesity to atherosclerosis.
Volume: 111
Issue: 15
Pages: 1946-53
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Publication
35643321 | J:341697
First Author: Schang G
Year: 2022
Journal: J Biol Chem
Title: Transcription factor GATA2 may potentiate follicle-stimulating hormone production in mice via induction of the BMP antagonist gremlin in gonadotrope cells.
Volume: 298
Issue: 7
Pages: 102072
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Publication
28943250 | J:322348
First Author: Tsukada M
Year: 2017
Journal: Stem Cell Reports
Title: In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells by Gfi1b, c-Fos, and Gata2 Overexpression within Teratoma.
Volume: 9
Issue: 4
Pages: 1024-1033
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Publication
30615908 | J:273317
 
First Author: Ishijima Y
Year: 2019
Journal: Mol Cell Endocrinol
Title: The Gata2 repression during 3T3-L1 preadipocyte differentiation is dependent on a rapid decrease in histone acetylation in response to glucocorticoid receptor activation.
Volume: 483
Pages: 39-49
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Protein
Q3B845
Organism: Mus musculus/domesticus
Length: 447  
Fragment?: false
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Publication
29277702 | J:267856
First Author: Li Y
Year: 2018
Journal: J Allergy Clin Immunol
Title: The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis.
Volume: 142
Issue: 4
Pages: 1173-1184
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Publication
30916783 | J:279388
First Author: Weiss AC
Year: 2019
Journal: J Pathol
Title: Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme.
Volume: 248
Issue: 4
Pages: 452-463
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Allele
Rr249<em3Ebres> | MGI:7330394
Name: regulatory region 249; endonuclease-mediated mutation 3, Emery H Bresnick
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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GXD Expression
GXD Expression
Probe: MGI:1339608
Assay Type: RNA in situ
Annotation Date: 1999-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:1342722
Age: embryonic day 10.5
Image: 2.G
Note: Expression is detected in a ventrolateral column spanning the hindbrain and spinal cord. Isl1 expression domain overlaps the Gata2 expression domain, with more ventral cells expressing only Isl1 and more dorsal cells express Gata2 or both Isl1 and Gata2.
Specimen Label: 2.G
Detected: true
Specimen Num: 8
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Allele
Rr249<em1Ebres> | MGI:7330389
Name: regulatory region 249; endonuclease-mediated mutation 1, Emery H Bresnick
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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•
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Allele
Rr249<em2Ebres> | MGI:7330390
Name: regulatory region 249; endonuclease-mediated mutation 2, Emery H Bresnick
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Publication
22996659 | J:191756
First Author: Johnson KD
Year: 2012
Journal: J Clin Invest
Title: Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity.
Volume: 122
Issue: 10
Pages: 3692-704
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Publication
34890222 | J:316415
First Author: Soukup AA
Year: 2021
Journal: Sci Adv
Title: Conditionally pathogenic genetic variants of a hematopoietic disease-suppressing enhancer.
Volume: 7
Issue: 50
Pages: eabk3521
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Publication
26601269 | J:259078
First Author: Johnson KD
Year: 2015
Journal: Sci Adv
Title: Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Volume: 1
Issue: 8
Pages: e1500503
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