Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506454 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-03-30 |
Strength: |
Strong |
Sex: |
Female |
Emaps: |
EMAPS:3152723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6513166 |
Age: |
embryonic day 15.5 |
Image: |
5 - Gata2 |
|
Specimen Label: |
5 - Gata2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506454 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-03-30 |
Strength: |
Strong |
Sex: |
Female |
Emaps: |
EMAPS:3152723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6513166 |
Age: |
embryonic day 15.5 |
Image: |
6 - Gata2 |
|
Specimen Label: |
6 - Gata2 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724457 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-03-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3152722 |
Pattern: |
Widespread |
Stage: |
TS22 |
Assay Id: |
MGI:6514163 |
Age: |
embryonic day 14.5 |
Image: |
8D - Gata2 |
|
Specimen Label: |
8D - Gata2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506454 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-03-30 |
Strength: |
Strong |
Sex: |
Female |
Emaps: |
EMAPS:2876523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:6513166 |
Age: |
embryonic day 15.5 |
Image: |
5 - Gata2 |
Note: |
Expression is seen in the upper third of the urethra. |
Specimen Label: |
5 - Gata2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506454 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-03-30 |
Strength: |
Strong |
Sex: |
Female |
Emaps: |
EMAPS:2875323 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:6513166 |
Age: |
embryonic day 15.5 |
Image: |
6 - Gata2 |
Note: |
Expression is seen in a banded pattern throughout the bladder neck and upper urethra. |
Specimen Label: |
6 - Gata2 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506454 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-03-30 |
Strength: |
Strong |
Sex: |
Female |
Emaps: |
EMAPS:3607823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:6513166 |
Age: |
embryonic day 15.5 |
Image: |
6 - Gata2 |
Note: |
Expression is seen in a banded pattern throughout the bladder neck and upper urethra. |
Specimen Label: |
6 - Gata2 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724457 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-03-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3607822 |
Pattern: |
Widespread |
Stage: |
TS22 |
Assay Id: |
MGI:6514163 |
Age: |
embryonic day 14.5 |
Image: |
8D - Gata2 |
|
Specimen Label: |
8D - Gata2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Onodera K |
Year: |
2016 |
Journal: |
Blood |
Title: |
GATA2 regulates dendritic cell differentiation. |
Volume: |
128 |
Issue: |
4 |
Pages: |
508-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Katayama S |
Year: |
2017 |
Journal: |
Blood |
Title: |
GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis. |
Volume: |
130 |
Issue: |
7 |
Pages: |
908-919 |
|
•
•
•
•
•
|
Publication |
First Author: |
You X |
Year: |
2021 |
Journal: |
Leukemia |
Title: |
Gata2 -77 enhancer regulates adult hematopoietic stem cell survival. |
Volume: |
35 |
Issue: |
3 |
Pages: |
901-905 |
|
•
•
•
•
•
|
Publication |
First Author: |
Soukup AA |
Year: |
2019 |
Journal: |
J Clin Invest |
Title: |
Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer. |
Volume: |
129 |
Issue: |
3 |
Pages: |
1180-1192 |
|
•
•
•
•
•
|
Publication |
First Author: |
Watanabe-Asaka T |
Year: |
2020 |
Journal: |
Genes Cells |
Title: |
GATA2 functions in adrenal chromaffin cells. |
Volume: |
25 |
Issue: |
9 |
Pages: |
607-614 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao X |
Year: |
2013 |
Journal: |
J Exp Med |
Title: |
Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo. |
Volume: |
210 |
Issue: |
13 |
Pages: |
2833-42 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724457 |
Assay Type: |
RNA in situ |
Annotation Date: |
2011-02-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684623 |
Pattern: |
Single cells |
Stage: |
TS23 |
Assay Id: |
MGI:4936866 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression is present in single cells in which the intercellular distance between stained cells is much larger than the cell diameter of an individual cell. A thumbnail photo of the staining is contained in the table. |
Specimen Label: |
Table S9 - Gata2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Harada N |
Year: |
2019 |
Journal: |
Cancer Sci |
Title: |
GATA2 hypomorphism induces chronic myelomonocytic leukemia in mice. |
Volume: |
110 |
Issue: |
4 |
Pages: |
1183-1193 |
|
•
•
•
•
•
|
Publication |
First Author: |
Katerndahl CDS |
Year: |
2021 |
Journal: |
Blood |
Title: |
Tumor suppressor function of Gata2 in acute promyelocytic leukemia. |
Volume: |
138 |
Issue: |
13 |
Pages: |
1148-1161 |
|
•
•
•
•
•
|
Publication |
First Author: |
Silvério-Alves R |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
GATA2 mitotic bookmarking is required for definitive haematopoiesis. |
Volume: |
14 |
Issue: |
1 |
Pages: |
4645 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ciciotte SL |
Year: |
1997 |
Journal: |
Mamm Genome |
Title: |
Gata2 maps to mouse chromosome 6. |
Volume: |
8 |
Issue: |
1 |
Pages: |
69-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lugus JJ |
Year: |
2007 |
Journal: |
Development |
Title: |
GATA2 functions at multiple steps in hemangioblast development and differentiation. |
Volume: |
134 |
Issue: |
2 |
Pages: |
393-405 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsai J |
Year: |
2005 |
Journal: |
EMBO Rep |
Title: |
The transcription factor GATA2 regulates differentiation of brown adipocytes. |
Volume: |
6 |
Issue: |
9 |
Pages: |
879-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khandekar M |
Year: |
2007 |
Journal: |
Development |
Title: |
A Gata2 intronic enhancer confers its pan-endothelia-specific regulation. |
Volume: |
134 |
Issue: |
9 |
Pages: |
1703-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Craven SE |
Year: |
2004 |
Journal: |
Development |
Title: |
Gata2 specifies serotonergic neurons downstream of sonic hedgehog. |
Volume: |
131 |
Issue: |
5 |
Pages: |
1165-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou Y |
Year: |
2000 |
Journal: |
Development |
Title: |
GATA2 is required for the generation of V2 interneurons. |
Volume: |
127 |
Issue: |
17 |
Pages: |
3829-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lim KC |
Year: |
2012 |
Journal: |
J Clin Invest |
Title: |
Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning. |
Volume: |
122 |
Issue: |
10 |
Pages: |
3705-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Charles MA |
Year: |
2006 |
Journal: |
Mol Endocrinol |
Title: |
Pituitary-specific Gata2 knockout: effects on gonadotrope and thyrotrope function. |
Volume: |
20 |
Issue: |
6 |
Pages: |
1366-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Malik J |
Year: |
2015 |
Journal: |
Mol Cell Biol |
Title: |
Histone methyltransferase Setd8 represses Gata2 expression and regulates erythroid maturation. |
Volume: |
35 |
Issue: |
12 |
Pages: |
2059-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
de Pater E |
Year: |
2013 |
Journal: |
J Exp Med |
Title: |
Gata2 is required for HSC generation and survival. |
Volume: |
210 |
Issue: |
13 |
Pages: |
2843-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kazenwadel J |
Year: |
2015 |
Journal: |
J Clin Invest |
Title: |
GATA2 is required for lymphatic vessel valve development and maintenance. |
Volume: |
125 |
Issue: |
8 |
Pages: |
2979-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khandekar M |
Year: |
2004 |
Journal: |
Mol Cell Biol |
Title: |
Multiple, distant Gata2 enhancers specify temporally and tissue-specific patterning in the developing urogenital system. |
Volume: |
24 |
Issue: |
23 |
Pages: |
10263-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li X |
Year: |
2016 |
Journal: |
Endocrinology |
Title: |
Gata2 Is a Rheostat for Mesenchymal Stem Cell Fate in Male Mice. |
Volume: |
157 |
Issue: |
3 |
Pages: |
1021-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ahmed N |
Year: |
2020 |
Journal: |
Stem Cell Reports |
Title: |
A Novel GATA2 Protein Reporter Mouse Reveals Hematopoietic Progenitor Cell Types. |
Volume: |
15 |
Issue: |
2 |
Pages: |
326-339 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takai J |
Year: |
2021 |
Journal: |
iScience |
Title: |
Gata2 heterozygous mutant mice exhibit reduced inflammatory responses and impaired bacterial clearance. |
Volume: |
24 |
Issue: |
8 |
Pages: |
102836 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hasegawa S |
Year: |
2017 |
Journal: |
Exp Hematol |
Title: |
Effects of in vivo deletion of GATA2 in bone marrow stromal cells. |
Volume: |
56 |
|
Pages: |
31-45.e2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar MS |
Year: |
2012 |
Journal: |
Cell |
Title: |
The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer. |
Volume: |
149 |
Issue: |
3 |
Pages: |
642-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kobayashi-Osaki M |
Year: |
2005 |
Journal: |
Mol Cell Biol |
Title: |
GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene. |
Volume: |
25 |
Issue: |
16 |
Pages: |
7005-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nozawa D |
Year: |
2009 |
Journal: |
Genes Cells |
Title: |
GATA2-dependent and region-specific regulation of Gata2 transcription in the mouse midbrain. |
Volume: |
14 |
Issue: |
5 |
Pages: |
569-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki M |
Year: |
2013 |
Journal: |
Genes Cells |
Title: |
GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation. |
Volume: |
18 |
Issue: |
11 |
Pages: |
921-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yin C |
Year: |
2020 |
Journal: |
Front Immunol |
Title: |
Efferocytic Defects in Early Atherosclerosis Are Driven by GATA2 Overexpression in Macrophages. |
Volume: |
11 |
|
Pages: |
594136 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
GATA2 regulates mast cell identity and responsiveness to antigenic stimulation by promoting chromatin remodeling at super-enhancers. |
Volume: |
12 |
Issue: |
1 |
Pages: |
494 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mahamud MR |
Year: |
2019 |
Journal: |
Development |
Title: |
GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126. |
Volume: |
146 |
Issue: |
21 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kala K |
Year: |
2009 |
Journal: |
Development |
Title: |
Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neurons. |
Volume: |
136 |
Issue: |
2 |
Pages: |
253-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qiu C |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis. |
Volume: |
8 |
|
Pages: |
15426 |
|
•
•
•
•
•
|
Publication |
First Author: |
Menendez-Gonzalez JB |
Year: |
2019 |
Journal: |
Stem Cell Reports |
Title: |
Gata2 as a Crucial Regulator of Stem Cells in Adult Hematopoiesis and Acute Myeloid Leukemia. |
Volume: |
13 |
Issue: |
2 |
Pages: |
291-306 |
|
•
•
•
•
•
|
Publication |
First Author: |
El Wakil A |
Year: |
2006 |
Journal: |
Development |
Title: |
The GATA2 transcription factor negatively regulates the proliferation of neuronal progenitors. |
Volume: |
133 |
Issue: |
11 |
Pages: |
2155-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lilleväli K |
Year: |
2004 |
Journal: |
Dev Dyn |
Title: |
Partially overlapping expression of Gata2 and Gata3 during inner ear development. |
Volume: |
231 |
Issue: |
4 |
Pages: |
775-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hasegawa A |
Year: |
2022 |
Journal: |
Commun Biol |
Title: |
Heterozygous variants in GATA2 contribute to DCML deficiency in mice by disrupting tandem protein binding. |
Volume: |
5 |
Issue: |
1 |
Pages: |
376 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu L |
Year: |
2017 |
Journal: |
Mol Cell Biol |
Title: |
Reducing Inflammatory Cytokine Production from Renal Collecting Duct Cells by Inhibiting GATA2 Ameliorates Acute Kidney Injury. |
Volume: |
37 |
Issue: |
22 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Nandakumar SK |
Year: |
2015 |
Journal: |
Exp Hematol |
Title: |
Low-level GATA2 overexpression promotes myeloid progenitor self-renewal and blocks lymphoid differentiation in mice. |
Volume: |
43 |
Issue: |
7 |
Pages: |
565-77.e1-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki N |
Year: |
2006 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Combinatorial Gata2 and Sca1 expression defines hematopoietic stem cells in the bone marrow niche. |
Volume: |
103 |
Issue: |
7 |
Pages: |
2202-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eich C |
Year: |
2018 |
Journal: |
J Exp Med |
Title: |
In vivo single cell analysis reveals Gata2 dynamics in cells transitioning to hematopoietic fate. |
Volume: |
215 |
Issue: |
1 |
Pages: |
233-248 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu L |
Year: |
2014 |
Journal: |
Mol Cell Biol |
Title: |
GATA2 regulates body water homeostasis through maintaining aquaporin 2 expression in renal collecting ducts. |
Volume: |
34 |
Issue: |
11 |
Pages: |
1929-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rubel CA |
Year: |
2012 |
Journal: |
Gene Expr Patterns |
Title: |
GATA2 is expressed at critical times in the mouse uterus during pregnancy. |
Volume: |
12 |
Issue: |
5-6 |
Pages: |
196-203 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shi X |
Year: |
2014 |
Journal: |
Dev Biol |
Title: |
Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages. |
Volume: |
389 |
Issue: |
2 |
Pages: |
208-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Haugas M |
Year: |
2010 |
Journal: |
Dev Dyn |
Title: |
Gata2 is required for the development of inner ear semicircular ducts and the surrounding perilymphatic space. |
Volume: |
239 |
Issue: |
9 |
Pages: |
2452-69 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tolkachov A |
Year: |
2018 |
Journal: |
Mol Cell Biol |
Title: |
Loss of the hematopoietic stem cell factor GATA2 in the osteogenic lineage impairs trabecularization and mechanical strength of bone. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Schupp M |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Re-expression of GATA2 cooperates with peroxisome proliferator-activated receptor-gamma depletion to revert the adipocyte phenotype. |
Volume: |
284 |
Issue: |
14 |
Pages: |
9458-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dasen JS |
Year: |
1999 |
Journal: |
Cell |
Title: |
Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types. |
Volume: |
97 |
Issue: |
5 |
Pages: |
587-98 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6173374 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6190373 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Gata2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6173374 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6190373 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Gata2 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6173374 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6190373 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Gata2 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6173374 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6190373 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Gata2 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6173374 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190373 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Gata2 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6173374 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190373 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Gata2 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6173374 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190373 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Gata2 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tondeleir D |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Beta-Actin Is Involved in Modulating Erythropoiesis during Development by Fine-Tuning Gata2 Expression Levels. |
Volume: |
8 |
Issue: |
6 |
Pages: |
e67855 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saida S |
Year: |
2020 |
Journal: |
Leukemia |
Title: |
Gata2 deficiency delays leukemogenesis while contributing to aggressive leukemia phenotype in Cbfb-MYH11 knockin mice. |
Volume: |
34 |
Issue: |
3 |
Pages: |
759-770 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang Z |
Year: |
2009 |
Journal: |
Mol Cell Biol |
Title: |
Increased c-Jun expression and reduced GATA2 expression promote aberrant monocytic differentiation induced by activating PTPN11 mutants. |
Volume: |
29 |
Issue: |
16 |
Pages: |
4376-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marks-Bluth J |
Year: |
2015 |
Journal: |
Mol Cell Biol |
Title: |
SMAD1 and SMAD5 Expression Is Coordinately Regulated by FLI1 and GATA2 during Endothelial Development. |
Volume: |
35 |
Issue: |
12 |
Pages: |
2165-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brandt W |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
Defining the functional boundaries of the Gata2 locus by rescue with a linked bacterial artificial chromosome transgene. |
Volume: |
283 |
Issue: |
14 |
Pages: |
8976-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Francius C |
Year: |
2015 |
Journal: |
Dev Neurobiol |
Title: |
Genetic dissection of Gata2 selective functions during specification of V2 interneurons in the developing spinal cord. |
Volume: |
75 |
Issue: |
7 |
Pages: |
721-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hoshino T |
Year: |
2008 |
Journal: |
Genes Cells |
Title: |
Reduced BMP4 abundance in Gata2 hypomorphic mutant mice result in uropathies resembling human CAKUT. |
Volume: |
13 |
Issue: |
2 |
Pages: |
159-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Robert-Moreno A |
Year: |
2005 |
Journal: |
Development |
Title: |
RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells. |
Volume: |
132 |
Issue: |
5 |
Pages: |
1117-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Haugas M |
Year: |
2016 |
Journal: |
Development |
Title: |
Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe. |
Volume: |
143 |
Issue: |
23 |
Pages: |
4495-4508 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ohmori S |
Year: |
2015 |
Journal: |
Blood |
Title: |
GATA2 is critical for the maintenance of cellular identity in differentiated mast cells derived from mouse bone marrow. |
Volume: |
125 |
Issue: |
21 |
Pages: |
3306-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tenney AP |
Year: |
2023 |
Journal: |
Nat Genet |
Title: |
Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis. |
Volume: |
55 |
Issue: |
7 |
Pages: |
1149-1163 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ohmori S |
Year: |
2019 |
Journal: |
Mol Cell Biol |
Title: |
GATA2 and PU.1 Collaborate To Activate the Expression of the Mouse Ms4a2 Gene, Encoding FcεRIβ, through Distinct Mechanisms. |
Volume: |
39 |
Issue: |
22 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ainoya K |
Year: |
2012 |
Journal: |
Mol Cell Biol |
Title: |
UG4 enhancer-driven GATA-2 and bone morphogenetic protein 4 complementation remedies the CAKUT phenotype in Gata2 hypomorphic mutant mice. |
Volume: |
32 |
Issue: |
12 |
Pages: |
2312-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Menghini R |
Year: |
2005 |
Journal: |
Circulation |
Title: |
Phosphorylation of GATA2 by Akt increases adipose tissue differentiation and reduces adipose tissue-related inflammation: a novel pathway linking obesity to atherosclerosis. |
Volume: |
111 |
Issue: |
15 |
Pages: |
1946-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schang G |
Year: |
2022 |
Journal: |
J Biol Chem |
Title: |
Transcription factor GATA2 may potentiate follicle-stimulating hormone production in mice via induction of the BMP antagonist gremlin in gonadotrope cells. |
Volume: |
298 |
Issue: |
7 |
Pages: |
102072 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsukada M |
Year: |
2017 |
Journal: |
Stem Cell Reports |
Title: |
In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells by Gfi1b, c-Fos, and Gata2 Overexpression within Teratoma. |
Volume: |
9 |
Issue: |
4 |
Pages: |
1024-1033 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishijima Y |
Year: |
2019 |
Journal: |
Mol Cell Endocrinol |
Title: |
The Gata2 repression during 3T3-L1 preadipocyte differentiation is dependent on a rapid decrease in histone acetylation in response to glucocorticoid receptor activation. |
Volume: |
483 |
|
Pages: |
39-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Froese N |
Year: |
2022 |
Journal: |
Biology (Basel) |
Title: |
Endothelial Cell GATA2 Modulates the Cardiomyocyte Stress Response through the Regulation of Two Long Non-Coding RNAs. |
Volume: |
11 |
Issue: |
12 |
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
447
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
2018 |
Journal: |
J Allergy Clin Immunol |
Title: |
The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis. |
Volume: |
142 |
Issue: |
4 |
Pages: |
1173-1184 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weiss AC |
Year: |
2019 |
Journal: |
J Pathol |
Title: |
Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme. |
Volume: |
248 |
Issue: |
4 |
Pages: |
452-463 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7717807 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-09-17 |
Strength: |
Trace |
Sex: |
Not Specified |
Emaps: |
EMAPS:2771120 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:7717887 |
Age: |
embryonic day 12.5 |
|
Note: |
Tissue-specific inactivation of Gata2 was confirmed by severe downregulation of expression in the ureteric mesenchyme of Tbx18;Gata2 (Gata2cKO) embryos. |
Specimen Label: |
S2 E12.5 Gata2cKO |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7717807 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-09-17 |
Strength: |
Trace |
Sex: |
Not Specified |
Emaps: |
EMAPS:2771121 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:7717887 |
Age: |
embryonic day 13.5 |
|
Note: |
Tissue-specific inactivation of Gata2 was confirmed by severe downregulation of expression in the ureteric mesenchyme of Tbx18;Gata2 (Gata2cKO) embryos. |
Specimen Label: |
S2 E13.5 Gata2cKO |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
Allele |
Name: |
regulatory region 249; endonuclease-mediated mutation 3, Emery H Bresnick |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified regulatory region |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1339608 |
Assay Type: |
RNA in situ |
Annotation Date: |
1999-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1609217 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:1342722 |
Age: |
embryonic day 10.5 |
Image: |
2.G |
Note: |
Expression is detected in a ventrolateral column spanning the hindbrain and spinal cord. Isl1 expression domain overlaps the Gata2 expression domain, with more ventral cells expressing only Isl1 and more dorsal cells express Gata2 or both Isl1 and Gata2. |
Specimen Label: |
2.G |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
Allele |
Name: |
regulatory region 249; endonuclease-mediated mutation 1, Emery H Bresnick |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified regulatory region |
|
•
•
•
•
•
|