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Search results 1 to 100 out of 312 for Gcgr

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0.041s
Type Details Score
Gene
Type: gene
Organism: Not Specified
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Yu R
Year: 2020
Journal: Biochem J
Title: The V369M Gcgr knock-in mice are a precision medicine model of mild Mahvash disease.
Volume: 477
Issue: 15
Pages: 2873-2874
Publication  
First Author: Liu Q
Year: 2021
Journal: Biosci Rep
Title: Deleterious mutation V369M in the mouse GCGR gene causes abnormal plasma amino acid levels indicative of a possible liver-α-cell axis.
Volume: 41
Issue: 6
Publication
First Author: Maharaj A
Year: 2012
Journal: Diabetologia
Title: Ectopic expression of glucagon receptor in skeletal muscles improves glucose homeostasis in a mouse model of diabetes.
Volume: 55
Issue: 5
Pages: 1458-68
Publication
First Author: Lin G
Year: 2020
Journal: Biochem J
Title: Characterization of a naturally occurring mutation V368M in the human glucagon receptor and its association with metabolic disorders.
Volume: 477
Issue: 13
Pages: 2581-2594
Publication
First Author: Hinds CE
Year: 2021
Journal: Sci Rep
Title: A glucagon analogue decreases body weight in mice via signalling in the liver.
Volume: 11
Issue: 1
Pages: 22577
Publication  
First Author: Yuan H
Year: 2023
Journal: Biochem Biophys Res Commun
Title: Crispr-Cas9 mediated complete deletion of glucagon receptor in mice display hyperglucagonemia and α-cell hyperplasia.
Volume: 643
Pages: 121-128
Publication
First Author: Lee Y
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Metabolic manifestations of insulin deficiency do not occur without glucagon action.
Volume: 109
Issue: 37
Pages: 14972-6
Publication  
First Author: Rivero-Gutierrez B
Year: 2018
Journal: Mol Metab
Title: Deletion of the glucagon receptor gene before and after experimental diabetes reveals differential protection from hyperglycemia.
Volume: 17
Pages: 28-38
Publication
First Author: Longuet C
Year: 2013
Journal: Diabetes
Title: Liver-specific disruption of the murine glucagon receptor produces α-cell hyperplasia: evidence for a circulating α-cell growth factor.
Volume: 62
Issue: 4
Pages: 1196-205
Publication
First Author: Mu J
Year: 2011
Journal: Diabetologia
Title: Chronic treatment with a glucagon receptor antagonist lowers glucose and moderately raises circulating glucagon and glucagon-like peptide 1 without severe alpha cell hypertrophy in diet-induced obese mice.
Volume: 54
Issue: 9
Pages: 2381-91
Publication
First Author: Sinclair EM
Year: 2008
Journal: Gastroenterology
Title: Glucagon receptor signaling is essential for control of murine hepatocyte survival.
Volume: 135
Issue: 6
Pages: 2096-106
Publication
First Author: Mukharji A
Year: 2013
Journal: Physiol Rep
Title: Oxyntomodulin increases intrinsic heart rate through the glucagon receptor.
Volume: 1
Issue: 5
Pages: e00112
Publication
First Author: Gelling RW
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Pancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and mass.
Volume: 297
Issue: 3
Pages: E695-707
Publication
First Author: Longuet C
Year: 2008
Journal: Cell Metab
Title: The glucagon receptor is required for the adaptive metabolic response to fasting.
Volume: 8
Issue: 5
Pages: 359-71
Publication
First Author: Sekar R
Year: 2022
Journal: Cell Metab
Title: Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes.
Volume: 34
Issue: 11
Pages: 1824-1842.e9
Publication
First Author: Lee Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells.
Volume: 111
Issue: 36
Pages: 13217-22
Publication
First Author: Han S
Year: 2013
Journal: J Lipid Res
Title: Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice.
Volume: 54
Issue: 10
Pages: 2615-22
Publication
First Author: Svendsen B
Year: 2018
Journal: Cell Rep
Title: Insulin Secretion Depends on Intra-islet Glucagon Signaling.
Volume: 25
Issue: 5
Pages: 1127-1134.e2
Publication
First Author: Umino Y
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: Partial rescue of retinal function in chronically hypoglycemic mice.
Volume: 53
Issue: 2
Pages: 915-23
Publication
First Author: Pocai A
Year: 2009
Journal: Diabetes
Title: Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice.
Volume: 58
Issue: 10
Pages: 2258-66
Publication
First Author: Du X
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: Differential effects of oxyntomodulin and GLP-1 on glucose metabolism.
Volume: 303
Issue: 2
Pages: E265-71
Publication
First Author: Ji L
Year: 2021
Journal: FEBS Lett
Title: The 14-3-3 protein YWHAB inhibits glucagon-induced hepatic gluconeogenesis through interacting with the glucagon receptor and FOXO1.
Volume: 595
Issue: 9
Pages: 1275-1288
Publication
First Author: Mu J
Year: 2012
Journal: PLoS One
Title: Anti-diabetic efficacy and impact on amino acid metabolism of GRA1, a novel small-molecule glucagon receptor antagonist.
Volume: 7
Issue: 11
Pages: e49572
Publication
First Author: Ali S
Year: 2015
Journal: Mol Metab
Title: Cardiomyocyte glucagon receptor signaling modulates outcomes in mice with experimental myocardial infarction.
Volume: 4
Issue: 2
Pages: 132-43
Publication
First Author: Malmgren S
Year: 2015
Journal: Diabetologia
Title: DPP-4 inhibition contributes to the prevention of hypoglycaemia through a GIP-glucagon counterregulatory axis in mice.
Volume: 58
Issue: 5
Pages: 1091-9
Publication
First Author: Ali S
Year: 2011
Journal: J Clin Invest
Title: Dual elimination of the glucagon and GLP-1 receptors in mice reveals plasticity in the incretin axis.
Volume: 121
Issue: 5
Pages: 1917-29
Publication
First Author: Mani BK
Year: 2017
Journal: Diabetes
Title: Hypoglycemic Effect of Combined Ghrelin and Glucagon Receptor Blockade.
Volume: 66
Issue: 7
Pages: 1847-1857
Publication
First Author: Neumann UH
Year: 2016
Journal: Mol Metab
Title: Glucagon receptor gene deletion in insulin knockout mice modestly reduces blood glucose and ketones but does not promote survival.
Volume: 5
Issue: 8
Pages: 731-736
Publication
First Author: Kim T
Year: 2018
Journal: Diabetes
Title: Hepatic Glucagon Receptor Signaling Enhances Insulin-Stimulated Glucose Disposal in Rodents.
Volume: 67
Issue: 11
Pages: 2157-2166
Publication
First Author: Kim T
Year: 2018
Journal: Diabetes
Title: Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21.
Volume: 67
Issue: 9
Pages: 1773-1782
Publication
First Author: Wang K
Year: 2023
Journal: Am J Physiol Endocrinol Metab
Title: Glucagon receptor blockage inhibits β-cell dedifferentiation through FoxO1.
Volume: 324
Issue: 1
Pages: E97-E113
Publication  
First Author: Nason SR
Year: 2020
Journal: Endocrinology
Title: Glucagon-Receptor Signaling Reverses Hepatic Steatosis Independent of Leptin Receptor Expression.
Volume: 161
Issue: 1
Publication
First Author: Habegger KM
Year: 2013
Journal: Diabetes
Title: Fibroblast growth factor 21 mediates specific glucagon actions.
Volume: 62
Issue: 5
Pages: 1453-63
Publication
First Author: Kedees MH
Year: 2009
Journal: Mol Cell Endocrinol
Title: Differential expression of glucagon and glucagon-like peptide 1 receptors in mouse pancreatic alpha and beta cells in two models of alpha cell hyperplasia.
Volume: 311
Issue: 1-2
Pages: 69-76
Publication  
First Author: Beaudry JL
Year: 2019
Journal: Mol Metab
Title: The brown adipose tissue glucagon receptor is functional but not essential for control of energy homeostasis in mice.
Volume: 22
Pages: 37-48
Publication
First Author: Vuguin PM
Year: 2006
Journal: Endocrinology
Title: Ablation of the glucagon receptor gene increases fetal lethality and produces alterations in islet development and maturation.
Volume: 147
Issue: 9
Pages: 3995-4006
Publication
First Author: Baggio LL
Year: 2017
Journal: Mol Metab
Title: The autonomic nervous system and cardiac GLP-1 receptors control heart rate in mice.
Volume: 6
Issue: 11
Pages: 1339-1349
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Burcelin R
Year: 1995
Journal: Gene
Title: Cloning and sequence analysis of the murine glucagon receptor-encoding gene.
Volume: 164
Issue: 2
Pages: 305-10
Publication
First Author: Gelling RW
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice.
Volume: 100
Issue: 3
Pages: 1438-43
Publication
First Author: Geiger A
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Structural and functional characterizations of the 5'-flanking region of the mouse glucagon receptor gene: comparison with the rat gene.
Volume: 272
Issue: 3
Pages: 912-21
Publication
First Author: Vasileva A
Year: 2022
Journal: Am J Physiol Endocrinol Metab
Title: Glucagon receptor signaling at white adipose tissue does not regulate lipolysis.
Volume: 323
Issue: 4
Pages: E389-E401
Publication
First Author: Shiao LL
Year: 1999
Journal: Transgenic Res
Title: Generation of mice expressing the human glucagon receptor with a direct replacement vector.
Volume: 8
Issue: 4
Pages: 295-302
Publication
First Author: Parker JC
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Glycemic control in mice with targeted disruption of the glucagon receptor gene.
Volume: 290
Issue: 2
Pages: 839-43
Publication  
First Author: Yang J
Year: 2011
Journal: BMC Genomics
Title: Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: implications on anti-glucagon therapies for diabetes.
Volume: 12
Pages: 281
Publication
First Author: Yu R
Year: 2012
Journal: Endocrinol Nutr
Title: Glucagon receptor is required for long-term survival: a natural history study of the Mahvash disease in a murine model.
Volume: 59
Issue: 9
Pages: 523-30
Publication
First Author: Yu R
Year: 2011
Journal: PLoS One
Title: Pancreatic neuroendocrine tumors in glucagon receptor-deficient mice.
Volume: 6
Issue: 8
Pages: e23397
Publication
First Author: Svendsen B
Year: 2021
Journal: Diabetologia
Title: Paracrine regulation of somatostatin secretion by insulin and glucagon in mouse pancreatic islets.
Volume: 64
Issue: 1
Pages: 142-151
Publication  
First Author: Hunt JE
Year: 2021
Journal: Front Endocrinol (Lausanne)
Title: Intestinal Growth in Glucagon Receptor Knockout Mice Is Not Associated With the Formation of AOM/DSS-Induced Tumors.
Volume: 12
Pages: 695145
Publication
First Author: Galsgaard KD
Year: 2020
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Glucagon receptor signaling is not required for N-carbamoyl glutamate- and l-citrulline-induced ureagenesis in mice.
Volume: 318
Issue: 5
Pages: G912-G927
Publication
First Author: Umino Y
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Hypoglycemia leads to age-related loss of vision.
Volume: 103
Issue: 51
Pages: 19541-5
Publication
First Author: Berglund ED
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: Glucagon and lipid interactions in the regulation of hepatic AMPK signaling and expression of PPARalpha and FGF21 transcripts in vivo.
Volume: 299
Issue: 4
Pages: E607-14
Publication
First Author: Lee Y
Year: 2011
Journal: Diabetes
Title: Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice.
Volume: 60
Issue: 2
Pages: 391-7
Publication
First Author: Townsend LK
Year: 2019
Journal: FASEB J
Title: Loss of glucagon signaling alters white adipose tissue browning.
Volume: 33
Issue: 4
Pages: 4824-4835
Publication
First Author: Sørensen H
Year: 2006
Journal: Diabetes
Title: Glucagon receptor knockout mice display increased insulin sensitivity and impaired beta-cell function.
Volume: 55
Issue: 12
Pages: 3463-9
Publication
First Author: Grigoryan M
Year: 2012
Journal: Endocrinology
Title: Regulation of mouse intestinal L cell progenitors proliferation by the glucagon family of peptides.
Volume: 153
Issue: 7
Pages: 3076-88
Publication
First Author: Omar BA
Year: 2014
Journal: Diabetes
Title: Fibroblast growth factor 21 (FGF21) and glucagon-like peptide 1 contribute to diabetes resistance in glucagon receptor-deficient mice.
Volume: 63
Issue: 1
Pages: 101-10
Publication
First Author: Elmelund E
Year: 2022
Journal: iScience
Title: Opposing effects of chronic glucagon receptor agonism and antagonism on amino acids, hepatic gene expression, and alpha cells.
Volume: 25
Issue: 11
Pages: 105296
Publication
First Author: Galsgaard KD
Year: 2018
Journal: Am J Physiol Endocrinol Metab
Title: Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis.
Volume: 314
Issue: 1
Pages: E93-E103
Publication
First Author: Berglund ED
Year: 2011
Journal: Diabetes
Title: Hepatic glucagon action is essential for exercise-induced reversal of mouse fatty liver.
Volume: 60
Issue: 11
Pages: 2720-9
Publication
First Author: Burcelin R
Year: 1998
Journal: J Biol Chem
Title: In vivo and in vitro regulation of hepatic glucagon receptor mRNA concentration by glucose metabolism.
Volume: 273
Issue: 14
Pages: 8088-93
Publication
First Author: Yu FX
Year: 2012
Journal: Cell
Title: Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling.
Volume: 150
Issue: 4
Pages: 780-91
GXD Expression      
Probe: MGI:2663031
Assay Type: Northern blot
Annotation Date: 2003-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2663041
Age: postnatal adult
Specimen Label: K
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2663033
Assay Type: RT-PCR
Annotation Date: 2003-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2663047
Age: postnatal week 2
Specimen Label: Kidney 2
Detected: true
Specimen Num: 23
GXD Expression      
Probe: MGI:2663033
Assay Type: RT-PCR
Annotation Date: 2003-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2663047
Age: postnatal week 5
Specimen Label: Kidney 5
Detected: true
Specimen Num: 24
GXD Expression      
Probe: MGI:2663033
Assay Type: RT-PCR
Annotation Date: 2003-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2663047
Age: postnatal week 12
Specimen Label: Kidney 12
Detected: true
Specimen Num: 25
GXD Expression      
Probe: MGI:2663033
Assay Type: RT-PCR
Annotation Date: 2003-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267826
Stage: TS26
Assay Id: MGI:2663052
Age: embryonic day 19.0
Specimen Label: Wildtype Fetal Day 19 B
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2663033
Assay Type: RT-PCR
Annotation Date: 2003-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Stage: TS28
Assay Id: MGI:2663052
Age: postnatal week 2
Specimen Label: Wildtype 2 weeks H
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:2663033
Assay Type: RT-PCR
Annotation Date: 2003-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Stage: TS28
Assay Id: MGI:2663052
Age: postnatal week 5
Specimen Label: Wildtype 5 weeks H
Detected: true
Specimen Num: 17
GXD Expression      
Probe: MGI:2663033
Assay Type: RT-PCR
Annotation Date: 2003-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Stage: TS28
Assay Id: MGI:2663052
Age: postnatal week 12
Specimen Label: Wildtype 12 weeks H
Detected: true
Specimen Num: 25
GXD Expression      
Probe: MGI:2663031
Assay Type: Northern blot
Annotation Date: 2003-06-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:2663041
Age: postnatal adult
Specimen Label: C
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:2663033
Assay Type: RT-PCR
Annotation Date: 2003-06-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1778726
Stage: TS26
Assay Id: MGI:2663052
Age: embryonic day 19.0
Specimen Label: Wildtype Fetal Day 19 CM
Detected: false
Specimen Num: 2